Black tea polyphenols induce human leukemic cell cycle arrest by inhibiting Akt signaling: Possible involvement of Hsp90, Wnt /β -catenin signaling and FOXO1

FEBS Journal

Volumn 279, Issue 16, 2012, Pages 2876-2891

  Halder, Babli ^a   Das Gupta, Shubho ^a   Gomes, Aparna ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

Akt signaling; FOXO1; Hsp90; TF and TR; Wnt catenin signaling

Indexed keywords

BETA CATENIN; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; GLYCOGEN SYNTHASE KINASE 3BETA; HEAT SHOCK PROTEIN 90; POLYPHENOL; PROTEIN KINASE B; PROTEIN P19; PROTEIN P21; PROTEIN P27; THEAFLAVIN DERIVATIVE; THEARUBIGIN DERIVATIVE; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG; WNT PROTEIN;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE REGULATION; CELL VIABILITY; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; HUMAN; HUMAN CELL; LEUKEMIA CELL; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TEA; THEA NIGRA; UPREGULATION;

APOPTOSIS; BETA CATENIN; BIFLAVONOIDS; CAMELLIA SINENSIS; CATECHIN; CELL CYCLE CHECKPOINTS; CYCLIN-DEPENDENT KINASES; FORKHEAD TRANSCRIPTION FACTORS; G1 PHASE; HSP90 HEAT-SHOCK PROTEINS; HUMANS; K562 CELLS; PHENOLS; POLYPHENOLS; PROTO-ONCOGENE PROTEINS C-AKT; U937 CELLS; WNT PROTEINS;

CAMELLIA SINENSIS;

EID: 84864411435     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2012.08668.x     Document Type: Article

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