p21 contains independent binding sites for cyclin and cdk2: Both sites are required to inhibit cdk2 kinase activity

Oncogene

Volumn 12, Issue 10, 1996, Pages 2155-2164

  Fotedar, Rati ^a   Fitzgerald, Patrick ^b   Rousselle, Tristan ^a   Cannella, Dominique ^a   Dorée, Marcel ^c   Messier, Helen ^b   Fotedar, Arun ^b  

^a INSTITUT DE BIOLOGIE STRUCTURALE   (France)

^b LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^c Centre National de la Recherche Scientifique   (France)

Author keywords

Cell cycle; Cyclin dependent kinase; Cyclin dependent kinase inhibitor; Domains of p21

Indexed keywords

CYCLIN DEPENDENT KINASE; CYCLINE; MUTANT PROTEIN; PROTEIN P21; RAS PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CONTROLLED STUDY; DELETION MUTANT; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; BACULOVIRIDAE; BINDING SITES; BURKITT LYMPHOMA; CDC2-CDC28 KINASES; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASES; CYCLINS; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDE MAPPING; PROTEIN-SERINE-THREONINE KINASES; SPODOPTERA; TUMOR CELLS, CULTURED;

EUKARYOTA;

EID: 0029948612     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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