Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of cdk2: Role of a caspase cascade

Molecular Cell

Volumn 1, Issue 4, 1998, Pages 553-563

  Levkau, Bodo ^a   Koyama, Hidenori ^a   Raines, Elaine W ^a   Clurman, Bruce E ^c   Herren, Barbara ^a   Orth, Kim ^b   Roberts, James M ^c   Ross, Russell ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c Fred Hutchinson Cancer Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASP3 PROTEIN, HUMAN; CASPASE; CASPASE 3; CDK2 PROTEIN, HUMAN; CDKN1A PROTEIN, HUMAN; CELL CYCLE PROTEIN; CYCLIN A; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN E; CYCLINE; CYSTEINE PROTEINASE; ENZYME INHIBITOR; ENZYME PRECURSOR; MICROTUBULE ASSOCIATED PROTEIN; PEPTIDE FRAGMENT; PROTEIN SERINE THREONINE KINASE; RECOMBINANT PROTEIN; TUMOR SUPPRESSOR PROTEIN;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL NUCLEUS; CHEMISTRY; CYTOLOGY; ENZYME ACTIVATION; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; MUTAGENESIS; PHYSIOLOGY; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

APOPTOSIS; CASPASE 3; CASPASES; CDC2-CDC28 KINASES; CELL CYCLE PROTEINS; CELL NUCLEUS; CELLS, CULTURED; CYCLIN A; CYCLIN E; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASES; CYCLINS; CYSTEINE ENDOPEPTIDASES; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; ENZYME INHIBITORS; ENZYME PRECURSORS; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; MUTAGENESIS; PEPTIDE FRAGMENTS; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; TRANSFECTION; TUMOR SUPPRESSOR PROTEINS; UMBILICAL VEINS;

EID: 0032012062     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80055-6     Document Type: Article

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