-
1
-
-
85006741530
-
Necroptosis in development, inflammation and disease
-
Weinlich R, Oberst A, Beere HM, Green DR. Necroptosis in development, inflammation and disease. Nat Rev Mol Cell Biol. 2016;18:127-136.
-
(2016)
Nat Rev Mol Cell Biol
, vol.18
, pp. 127-136
-
-
Weinlich, R.1
Oberst, A.2
Beere, H.M.3
Green, D.R.4
-
2
-
-
84894550453
-
Regulated necrosis: The expanding network of non-apoptotic cell death pathways
-
Vanden Berghe T, Linkermann A, Jouan-Lanhouet S, Walczak H, Vandenabeele P. Regulated necrosis: The expanding network of non-apoptotic cell death pathways. Nat Rev Mol Cell Biol. 2014;15:135-147.
-
(2014)
Nat Rev Mol Cell Biol
, vol.15
, pp. 135-147
-
-
Vanden Berghe, T.1
Linkermann, A.2
Jouan-Lanhouet, S.3
Walczak, H.4
Vandenabeele, P.5
-
3
-
-
84952630550
-
Converging roles of caspases in inflammasome activation, cell death and innate immunity
-
Man SM, Kanneganti TD. Converging roles of caspases in inflammasome activation, cell death and innate immunity. Nat Rev Immunol. 2016;16:7-21.
-
(2016)
Nat Rev Immunol
, vol.16
, pp. 7-21
-
-
Man, S.M.1
Kanneganti, T.D.2
-
4
-
-
84927671957
-
Programmed necrosis in the cross talk of cell death and inflammation
-
Chan FK, Luz NF, Moriwaki K. Programmed necrosis in the cross talk of cell death and inflammation. Annu Rev Immunol. 2015;33:79-106.
-
(2015)
Annu Rev Immunol
, vol.33
, pp. 79-106
-
-
Chan, F.K.1
Luz, N.F.2
Moriwaki, K.3
-
5
-
-
84906535354
-
A long-awaited merger of the pathways mediating host defence and programmed cell death
-
Blander JM. A long-awaited merger of the pathways mediating host defence and programmed cell death. Nat Rev Immunol. 2014;14:601-618.
-
(2014)
Nat Rev Immunol
, vol.14
, pp. 601-618
-
-
Blander, J.M.1
-
8
-
-
84923880478
-
Inflammatory outcomes of apoptosis, necrosis and necroptosis
-
Davidovich P, Kearney CJ, Martin SJ. Inflammatory outcomes of apoptosis, necrosis and necroptosis. Biol Chem. 2014;395:1163-1171.
-
(2014)
Biol Chem
, vol.395
, pp. 1163-1171
-
-
Davidovich, P.1
Kearney, C.J.2
Martin, S.J.3
-
9
-
-
84915805120
-
Caspase crosstalk: Integration of apoptotic and innate immune signalling pathways
-
Creagh EM. Caspase crosstalk: Integration of apoptotic and innate immune signalling pathways. Trends Immunol. 2014;35:631-640.
-
(2014)
Trends Immunol
, vol.35
, pp. 631-640
-
-
Creagh, E.M.1
-
10
-
-
0032482169
-
Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor
-
Vercammen D, Beyaert R, Denecker G, et al. Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor. J Exp Med. 1998;187:1477-1485.
-
(1998)
J Exp Med
, vol.187
, pp. 1477-1485
-
-
Vercammen, D.1
Beyaert, R.2
Denecker, G.3
-
11
-
-
5944233768
-
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule
-
Holler N, Zaru R, Micheau O, et al. Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat Immunol. 2000;1:489-495.
-
(2000)
Nat Immunol
, vol.1
, pp. 489-495
-
-
Holler, N.1
Zaru, R.2
Micheau, O.3
-
13
-
-
15644374367
-
Shigella-induced apoptosis is dependent on caspase-1 which binds to IpaB
-
Hilbi H, Moss JE, Hersh D, et al. Shigella-induced apoptosis is dependent on caspase-1 which binds to IpaB. J Biol Chem. 1998;273:32895-32900.
-
(1998)
J Biol Chem
, vol.273
, pp. 32895-32900
-
-
Hilbi, H.1
Moss, J.E.2
Hersh, D.3
-
14
-
-
0033515032
-
The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1
-
Hersh D, Monack DM, Smith MR, Ghori N, Falkow S, Zychlinsky A. The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1. Proc Natl Acad Sci USA. 1999;96:2396-2401.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 2396-2401
-
-
Hersh, D.1
Monack, D.M.2
Smith, M.R.3
Ghori, N.4
Falkow, S.5
Zychlinsky, A.6
-
15
-
-
0002928890
-
Identification of a monocyte specific pre-interleukin 1 beta convertase activity
-
Kostura MJ, Tocci MJ, Limjuco G, et al. Identification of a monocyte specific pre-interleukin 1 beta convertase activity. Proc Natl Acad Sci USA. 1989;86:5227-5231.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 5227-5231
-
-
Kostura, M.J.1
Tocci, M.J.2
Limjuco, G.3
-
16
-
-
0024510020
-
Activation of interleukin-1 beta by a co-induced protease
-
Black RA, Kronheim SR, Sleath PR. Activation of interleukin-1 beta by a co-induced protease. FEBS Lett. 1989;247:386-390.
-
(1989)
FEBS Lett
, vol.247
, pp. 386-390
-
-
Black, R.A.1
Kronheim, S.R.2
Sleath, P.R.3
-
17
-
-
0031004174
-
Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production
-
Ghayur T, Banerjee S, Hugunin M, et al. Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production. Nature. 1997;386:619-623.
-
(1997)
Nature
, vol.386
, pp. 619-623
-
-
Ghayur, T.1
Banerjee, S.2
Hugunin, M.3
-
18
-
-
0026507126
-
A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes
-
Thornberry NA, Bull HG, Calaycay JR, et al. A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes. Nature. 1992;356:768-774.
-
(1992)
Nature
, vol.356
, pp. 768-774
-
-
Thornberry, N.A.1
Bull, H.G.2
Calaycay, J.R.3
-
19
-
-
0035283318
-
Pro-inflammatory programmed cell death
-
Cookson BT, Brennan MA. Pro-inflammatory programmed cell death. Trends Microbiol. 2001;9:113-114.
-
(2001)
Trends Microbiol
, vol.9
, pp. 113-114
-
-
Cookson, B.T.1
Brennan, M.A.2
-
20
-
-
84927732725
-
Regulation of inflammasome activation
-
Man SM, Kanneganti TD. Regulation of inflammasome activation. Immunol Rev. 2015;265:6-21.
-
(2015)
Immunol Rev
, vol.265
, pp. 6-21
-
-
Man, S.M.1
Kanneganti, T.D.2
-
21
-
-
84965107840
-
Inflammasome complexes: Emerging mechanisms and effector functions
-
Rathinam VA, Fitzgerald KA. Inflammasome complexes: Emerging mechanisms and effector functions. Cell. 2016;165:792-800.
-
(2016)
Cell
, vol.165
, pp. 792-800
-
-
Rathinam, V.A.1
Fitzgerald, K.A.2
-
22
-
-
84901310586
-
Mechanisms and functions of inflammasomes
-
Lamkanfi M, Dixit VM. Mechanisms and functions of inflammasomes. Cell. 2014;157:1013-1022.
-
(2014)
Cell
, vol.157
, pp. 1013-1022
-
-
Lamkanfi, M.1
Dixit, V.M.2
-
23
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
Martinon F, Burns K, Tschopp J. The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell. 2002;10:417-426.
-
(2002)
Mol Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
24
-
-
84942892037
-
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
-
Shi J, Zhao Y, Wang K, et al. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death. Nature. 2015;526:660-665.
-
(2015)
Nature
, vol.526
, pp. 660-665
-
-
Shi, J.1
Zhao, Y.2
Wang, K.3
-
25
-
-
84942856523
-
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signaling
-
Kayagaki N, Stowe IB, Lee BL, et al. Caspase-11 cleaves gasdermin D for non-canonical inflammasome signaling. Nature. 2015;526:666-671.
-
(2015)
Nature
, vol.526
, pp. 666-671
-
-
Kayagaki, N.1
Stowe, I.B.2
Lee, B.L.3
-
26
-
-
84949091051
-
Gasdermin D is an executor of pyroptosis and required for interleukin-1beta secretion
-
He WT, Wan H, Hu L, et al. Gasdermin D is an executor of pyroptosis and required for interleukin-1beta secretion. Cell Res. 2015;25:1285-1298.
-
(2015)
Cell Res
, vol.25
, pp. 1285-1298
-
-
He, W.T.1
Wan, H.2
Hu, L.3
-
27
-
-
84978419608
-
Pore-forming activity and structural autoinhibition of the gasdermin family
-
Ding J, Wang K, Liu W, et al. Pore-forming activity and structural autoinhibition of the gasdermin family. Nature. 2016;535:111-116.
-
(2016)
Nature
, vol.535
, pp. 111-116
-
-
Ding, J.1
Wang, K.2
Liu, W.3
-
28
-
-
84978128481
-
GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes
-
Aglietti RA, Estevez A, Gupta A, et al. GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes. Proc Natl Acad Sci USA. 2016;113:7858-7863.
-
(2016)
Proc Natl Acad Sci USA
, vol.113
, pp. 7858-7863
-
-
Aglietti, R.A.1
Estevez, A.2
Gupta, A.3
-
29
-
-
84978374487
-
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
-
Liu X, Zhang Z, Ruan J, et al. Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores. Nature. 2016;535:153-158.
-
(2016)
Nature
, vol.535
, pp. 153-158
-
-
Liu, X.1
Zhang, Z.2
Ruan, J.3
-
30
-
-
84982102736
-
GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death
-
Sborgi L, Ruhl S, Mulvihill E, et al. GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death. EMBO J. 2016;35:1766-1778.
-
(2016)
EMBO J
, vol.35
, pp. 1766-1778
-
-
Sborgi, L.1
Ruhl, S.2
Mulvihill, E.3
-
31
-
-
84984822442
-
Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis
-
Chen X, He WT, Hu L, et al. Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis. Cell Res. 2016;26:1007-1020.
-
(2016)
Cell Res
, vol.26
, pp. 1007-1020
-
-
Chen, X.1
He, W.T.2
Hu, L.3
-
32
-
-
80455176839
-
Non-canonical inflammasome activation targets caspase-11
-
Kayagaki N, Warming S, Lamkanfi M, et al. Non-canonical inflammasome activation targets caspase-11. Nature. 2011;479:117-121.
-
(2011)
Nature
, vol.479
, pp. 117-121
-
-
Kayagaki, N.1
Warming, S.2
Lamkanfi, M.3
-
33
-
-
0034192466
-
Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions
-
Kang SJ, Wang S, Hara H, et al. Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions. J Cell Biol. 2000;149:613-622.
-
(2000)
J Cell Biol
, vol.149
, pp. 613-622
-
-
Kang, S.J.1
Wang, S.2
Hara, H.3
-
34
-
-
0028920863
-
Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme
-
Kuida K, Lippke JA, Ku G, et al. Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme. Science. 1995;267:2000-2003.
-
(1995)
Science
, vol.267
, pp. 2000-2003
-
-
Kuida, K.1
Lippke, J.A.2
Ku, G.3
-
35
-
-
0028984948
-
Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock
-
Li P, Allen H, Banerjee S, et al. Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock. Cell. 1995;80:401-411.
-
(1995)
Cell
, vol.80
, pp. 401-411
-
-
Li, P.1
Allen, H.2
Banerjee, S.3
-
36
-
-
85018952918
-
Generation of a caspase-1-deficient mouse line to study the differential roles of caspase-1 and caspase-11 inflammasomes
-
Man SM, Karki R, Briard B, et al. Generation of a caspase-1-deficient mouse line to study the differential roles of caspase-1 and caspase-11 inflammasomes. Sci Rep. 2017; https://doi.org/10.1038/srep45126.
-
(2017)
Sci Rep
-
-
Man, S.M.1
Karki, R.2
Briard, B.3
-
37
-
-
84873202976
-
Caspase-11 stimulates rapid flagellin-independent pyroptosis in response to Legionella pneumophila
-
Case CL, Kohler LJ, Lima JB, et al. Caspase-11 stimulates rapid flagellin-independent pyroptosis in response to Legionella pneumophila. Proc Natl Acad Sci USA. 2013;110:1851-1856.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 1851-1856
-
-
Case, C.L.1
Kohler, L.J.2
Lima, J.B.3
-
38
-
-
84994507182
-
The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury
-
Hu B, Jin C, Li HB, et al. The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury. Science. 2016;354:765-768.
-
(2016)
Science
, vol.354
, pp. 765-768
-
-
Hu, B.1
Jin, C.2
Li, H.B.3
-
39
-
-
84927732727
-
Caspase-11: Arming the guards against bacterial infection
-
Stowe I, Lee B, Kayagaki N. Caspase-11: Arming the guards against bacterial infection. Immunol Rev. 2015;265:75-84.
-
(2015)
Immunol Rev
, vol.265
, pp. 75-84
-
-
Stowe, I.1
Lee, B.2
Kayagaki, N.3
-
40
-
-
41949127121
-
Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms
-
Fink SL, Bergsbaken T, Cookson BT. Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms. Proc Natl Acad Sci USA. 2008;105:4312-4317.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 4312-4317
-
-
Fink, S.L.1
Bergsbaken, T.2
Cookson, B.T.3
-
41
-
-
33749576792
-
Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages
-
Fink SL, Cookson BT. Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages. Cell Microbiol. 2006;8:1812-1825.
-
(2006)
Cell Microbiol
, vol.8
, pp. 1812-1825
-
-
Fink, S.L.1
Cookson, B.T.2
-
42
-
-
34548031870
-
The pyroptosome: A supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
-
Fernandes-Alnemri T, Wu J, Yu JW, et al. The pyroptosome: A supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation. Cell Death Differ. 2007;14:1590-1604.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1590-1604
-
-
Fernandes-Alnemri, T.1
Wu, J.2
Yu, J.W.3
-
43
-
-
84975453384
-
The cell biology of inflammasomes: Mechanisms of inflammasome activation and regulation
-
Sharma D, Kanneganti TD. The cell biology of inflammasomes: Mechanisms of inflammasome activation and regulation. J Cell Biol. 2016;213:617-629.
-
(2016)
J Cell Biol
, vol.213
, pp. 617-629
-
-
Sharma, D.1
Kanneganti, T.D.2
-
44
-
-
84862777872
-
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis
-
Shimada K, Crother TR, Karlin J, et al. Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. Immunity. 2012;36:401-414.
-
(2012)
Immunity
, vol.36
, pp. 401-414
-
-
Shimada, K.1
Crother, T.R.2
Karlin, J.3
-
45
-
-
3142654767
-
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
-
Mariathasan S, Newton K, Monack DM, et al. Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature. 2004;430:213-218.
-
(2004)
Nature
, vol.430
, pp. 213-218
-
-
Mariathasan, S.1
Newton, K.2
Monack, D.M.3
-
46
-
-
84902142180
-
Release of interleukin-1alpha or interleukin-1beta depends on mechanism of cell death
-
England H, Summersgill HR, Edye ME, Rothwell NJ, Brough D. Release of interleukin-1alpha or interleukin-1beta depends on mechanism of cell death. J Biol Chem. 2014;289:15942-15950.
-
(2014)
J Biol Chem
, vol.289
, pp. 15942-15950
-
-
England, H.1
Summersgill, H.R.2
Edye, M.E.3
Rothwell, N.J.4
Brough, D.5
-
47
-
-
77958125448
-
Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia
-
Lamkanfi M, Sarkar A, Vande Walle L, et al. Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia. J Immunol. 2010;185:4385-4392.
-
(2010)
J Immunol
, vol.185
, pp. 4385-4392
-
-
Lamkanfi, M.1
Sarkar, A.2
Vande Walle, L.3
-
48
-
-
58849151813
-
Cutting edge: Critical role for mesothelial cells in necrosis-induced inflammation through the recognition of IL-1 alpha released from dying cells
-
Eigenbrod T, Park JH, Harder J, Iwakura Y, Nunez G. Cutting edge: Critical role for mesothelial cells in necrosis-induced inflammation through the recognition of IL-1 alpha released from dying cells. J Immunol. 2008;181:8194-8198.
-
(2008)
J Immunol
, vol.181
, pp. 8194-8198
-
-
Eigenbrod, T.1
Park, J.H.2
Harder, J.3
Iwakura, Y.4
Nunez, G.5
-
49
-
-
34447116244
-
Identification of a key pathway required for the sterile inflammatory response triggered by dying cells
-
Chen CJ, Kono H, Golenbock D, Reed G, Akira S, Rock KL. Identification of a key pathway required for the sterile inflammatory response triggered by dying cells. Nat Med. 2007;13:851-856.
-
(2007)
Nat Med
, vol.13
, pp. 851-856
-
-
Chen, C.J.1
Kono, H.2
Golenbock, D.3
Reed, G.4
Akira, S.5
Rock, K.L.6
-
50
-
-
79955897768
-
Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions
-
Dombrowski Y, Peric M, Koglin S, et al. Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions. Sci Transl Med. 2011;3:82ra38.
-
(2011)
Sci Transl Med
, vol.3
, pp. 82
-
-
Dombrowski, Y.1
Peric, M.2
Koglin, S.3
-
51
-
-
84892852797
-
Interleukin-1beta in innate inflammation, autophagy and immunity
-
Joosten LA, Netea MG, Dinarello CA. Interleukin-1beta in innate inflammation, autophagy and immunity. Semin Immunol. 2013;25:416-424.
-
(2013)
Semin Immunol
, vol.25
, pp. 416-424
-
-
Joosten, L.A.1
Netea, M.G.2
Dinarello, C.A.3
-
53
-
-
84904692363
-
The adaptor ASC has extracellular and ‘prionoid’ activities that propagate inflammation
-
Franklin BS, Bossaller L, De Nardo D, et al. The adaptor ASC has extracellular and ‘prionoid’ activities that propagate inflammation. Nat Immunol. 2014;15:727-737.
-
(2014)
Nat Immunol
, vol.15
, pp. 727-737
-
-
Franklin, B.S.1
Bossaller, L.2
De Nardo, D.3
-
54
-
-
84904646033
-
The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response
-
Baroja-Mazo A, Martin-Sanchez F, Gomez AI, et al. The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response. Nat Immunol. 2014;15:738-748.
-
(2014)
Nat Immunol
, vol.15
, pp. 738-748
-
-
Baroja-Mazo, A.1
Martin-Sanchez, F.2
Gomez, A.I.3
-
55
-
-
84861214708
-
Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome
-
Levinsohn JL, Newman ZL, Hellmich KA, et al. Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome. PLoS Pathog. 2012;8:e1002638.
-
(2012)
PLoS Pathog
, vol.8
-
-
Levinsohn, J.L.1
Newman, Z.L.2
Hellmich, K.A.3
-
56
-
-
84869073837
-
Anthrax lethal factor cleaves mouse nlrp1b in both toxin-sensitive and toxin-resistant macrophages
-
Hellmich KA, Levinsohn JL, Fattah R, et al. Anthrax lethal factor cleaves mouse nlrp1b in both toxin-sensitive and toxin-resistant macrophages. PLoS ONE. 2012;7:e49741.
-
(2012)
PLoS ONE
, vol.7
-
-
Hellmich, K.A.1
Levinsohn, J.L.2
Fattah, R.3
-
57
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariathasan S, Weiss DS, Newton K, et al. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature. 2006;440:228-232.
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
-
58
-
-
32944462834
-
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
-
Kanneganti TD, Ozoren N, Body-Malapel M, et al. Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature. 2006;440:233-236.
-
(2006)
Nature
, vol.440
, pp. 233-236
-
-
Kanneganti, T.D.1
Ozoren, N.2
Body-Malapel, M.3
-
59
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature. 2006;440:237-241.
-
(2006)
Nature
, vol.440
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
60
-
-
84958971929
-
NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux
-
He Y, Zeng MY, Yang D, Motro B, Nunez G. NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux. Nature. 2016;530:354-357.
-
(2016)
Nature
, vol.530
, pp. 354-357
-
-
He, Y.1
Zeng, M.Y.2
Yang, D.3
Motro, B.4
Nunez, G.5
-
61
-
-
84949595485
-
NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component
-
Shi H, Wang Y, Li X, et al. NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component. Nat Immunol. 2016;17:250-258.
-
(2016)
Nat Immunol
, vol.17
, pp. 250-258
-
-
Shi, H.1
Wang, Y.2
Li, X.3
-
62
-
-
84952931119
-
A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) screen identifies NEK7 as an essential component of NLRP3 inflammasome activation
-
Schmid-Burgk JL, Chauhan D, Schmidt T, et al. A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) screen identifies NEK7 as an essential component of NLRP3 inflammasome activation. J Biol Chem. 2016;291:103-109.
-
(2016)
J Biol Chem
, vol.291
, pp. 103-109
-
-
Schmid-Burgk, J.L.1
Chauhan, D.2
Schmidt, T.3
-
63
-
-
80053379974
-
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
-
Kofoed EM, Vance RE. Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity. Nature. 2011;477:592-595.
-
(2011)
Nature
, vol.477
, pp. 592-595
-
-
Kofoed, E.M.1
Vance, R.E.2
-
64
-
-
80053349020
-
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
-
Zhao Y, Yang J, Shi J, et al. The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Nature. 2011;477:596-600.
-
(2011)
Nature
, vol.477
, pp. 596-600
-
-
Zhao, Y.1
Yang, J.2
Shi, J.3
-
65
-
-
84883329029
-
Human NAIP and mouse NAIP1 recognize bacterial type III secretion needle protein for inflammasome activation
-
Yang J, Zhao Y, Shi J, Shao F. Human NAIP and mouse NAIP1 recognize bacterial type III secretion needle protein for inflammasome activation. Proc Natl Acad Sci USA. 2013;110:14408-14413.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 14408-14413
-
-
Yang, J.1
Zhao, Y.2
Shi, J.3
Shao, F.4
-
66
-
-
84885439494
-
Cutting edge: Mouse NAIP1 detects the type III secretion system needle protein
-
Rayamajhi M, Zak DE, Chavarria-Smith J, Vance RE, Miao EA. Cutting edge: Mouse NAIP1 detects the type III secretion system needle protein. J Immunol. 2013;191:3986-3989.
-
(2013)
J Immunol
, vol.191
, pp. 3986-3989
-
-
Rayamajhi, M.1
Zak, D.E.2
Chavarria-Smith, J.3
Vance, R.E.4
Miao, E.A.5
-
67
-
-
33744464740
-
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages
-
Franchi L, Amer A, Body-Malapel M, et al. Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages. Nat Immunol. 2006;7:576-582.
-
(2006)
Nat Immunol
, vol.7
, pp. 576-582
-
-
Franchi, L.1
Amer, A.2
Body-Malapel, M.3
-
68
-
-
33744493091
-
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf
-
Miao EA, Alpuche-Aranda CM, Dors M, et al. Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf. Nat Immunol. 2006;7:569-575.
-
(2006)
Nat Immunol
, vol.7
, pp. 569-575
-
-
Miao, E.A.1
Alpuche-Aranda, C.M.2
Dors, M.3
-
69
-
-
77649241461
-
Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome
-
Miao EA, Mao DP, Yudkovsky N, et al. Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome. Proc Natl Acad Sci USA. 2010;107:3076-3080.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 3076-3080
-
-
Miao, E.A.1
Mao, D.P.2
Yudkovsky, N.3
-
70
-
-
84937706079
-
Cutting edge: Inflammasome activation in primary human macrophages is dependent on flagellin
-
Kortmann J, Brubaker SW, Monack DM. Cutting edge: Inflammasome activation in primary human macrophages is dependent on flagellin. J Immunol. 2015;195:815-819.
-
(2015)
J Immunol
, vol.195
, pp. 815-819
-
-
Kortmann, J.1
Brubaker, S.W.2
Monack, D.M.3
-
71
-
-
84898031590
-
Molecular basis for specific recognition of bacterial ligands by NAIP/NLRC4 inflammasomes
-
Tenthorey JL, Kofoed EM, Daugherty MD, Malik HS, Vance RE. Molecular basis for specific recognition of bacterial ligands by NAIP/NLRC4 inflammasomes. Mol Cell. 2014;54:17-29.
-
(2014)
Mol Cell
, vol.54
, pp. 17-29
-
-
Tenthorey, J.L.1
Kofoed, E.M.2
Daugherty, M.D.3
Malik, H.S.4
Vance, R.E.5
-
72
-
-
63649133278
-
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
-
Hornung V, Ablasser A, Charrel-Dennis M, et al. AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature. 2009;458:514-518.
-
(2009)
Nature
, vol.458
, pp. 514-518
-
-
Hornung, V.1
Ablasser, A.2
Charrel-Dennis, M.3
-
73
-
-
63649145255
-
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
-
Fernandes-Alnemri T, Yu JW, Datta P, Wu J, Alnemri ES. AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature. 2009;458:509-513.
-
(2009)
Nature
, vol.458
, pp. 509-513
-
-
Fernandes-Alnemri, T.1
Yu, J.W.2
Datta, P.3
Wu, J.4
Alnemri, E.S.5
-
74
-
-
60749136484
-
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
-
Burckstummer T, Baumann C, Bluml S, et al. An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. Nat Immunol. 2009;10:266-272.
-
(2009)
Nat Immunol
, vol.10
, pp. 266-272
-
-
Burckstummer, T.1
Baumann, C.2
Bluml, S.3
-
75
-
-
60749104535
-
HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA
-
Roberts TL, Idris A, Dunn JA, et al. HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA. Science. 2009;323:1057-1060.
-
(2009)
Science
, vol.323
, pp. 1057-1060
-
-
Roberts, T.L.1
Idris, A.2
Dunn, J.A.3
-
76
-
-
84859403876
-
Activation of the pyrin inflammasome by intracellular Burkholderia cenocepacia
-
Gavrilin MA, Abdelaziz DH, Mostafa M, et al. Activation of the pyrin inflammasome by intracellular Burkholderia cenocepacia. J Immunol. 2012;188:3469-3477.
-
(2012)
J Immunol
, vol.188
, pp. 3469-3477
-
-
Gavrilin, M.A.1
Abdelaziz, D.H.2
Mostafa, M.3
-
77
-
-
84907270863
-
Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome
-
Xu H, Yang J, Gao W, et al. Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome. Nature. 2014;513:237-241.
-
(2014)
Nature
, vol.513
, pp. 237-241
-
-
Xu, H.1
Yang, J.2
Gao, W.3
-
78
-
-
84964664672
-
A Burkholderia type VI effector deamidates Rho GTPases to activate the pyrin inflammasome and trigger inflammation
-
Aubert DF, Xu H, Yang J, et al. A Burkholderia type VI effector deamidates Rho GTPases to activate the pyrin inflammasome and trigger inflammation. Cell Host Microbe. 2016;19:664-674.
-
(2016)
Cell Host Microbe
, vol.19
, pp. 664-674
-
-
Aubert, D.F.1
Xu, H.2
Yang, J.3
-
79
-
-
85005992585
-
Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation
-
Van Gorp H, Saavedra PH, de Vasconcelos NM, et al. Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation. Proc Natl Acad Sci USA. 2016;113:14384-14389.
-
(2016)
Proc Natl Acad Sci USA
, vol.113
, pp. 14384-14389
-
-
Van Gorp, H.1
Saavedra, P.H.2
de Vasconcelos, N.M.3
-
80
-
-
84976329660
-
Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS
-
Park YH, Wood G, Kastner DL, Chae JJ. Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS. Nat Immunol. 2016;17:914-921.
-
(2016)
Nat Immunol
, vol.17
, pp. 914-921
-
-
Park, Y.H.1
Wood, G.2
Kastner, D.L.3
Chae, J.J.4
-
81
-
-
84962744592
-
Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation
-
Masters SL, Lagou V, Jeru I, et al. Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation. Sci Transl Med. 2016;8:332ra345.
-
(2016)
Sci Transl Med
, vol.8
, pp. 332
-
-
Masters, S.L.1
Lagou, V.2
Jeru, I.3
-
82
-
-
84982091531
-
Site-specific phosphorylation and microtubule dynamics control Pyrin inflammasome activation
-
Gao W, Yang J, Liu W, Wang Y, Shao F. Site-specific phosphorylation and microtubule dynamics control Pyrin inflammasome activation. Proc Natl Acad Sci USA. 2016;113:E4857-E4866.
-
(2016)
Proc Natl Acad Sci USA
, vol.113
, pp. 4857-4866
-
-
Gao, W.1
Yang, J.2
Liu, W.3
Wang, Y.4
Shao, F.5
-
83
-
-
0000814155
-
Nucleotide sequence of human monocyte interleukin 1 precursor cDNA
-
Auron PE, Webb AC, Rosenwasser LJ, et al. Nucleotide sequence of human monocyte interleukin 1 precursor cDNA. Proc Natl Acad Sci USA. 1984;81:7907-7911.
-
(1984)
Proc Natl Acad Sci USA
, vol.81
, pp. 7907-7911
-
-
Auron, P.E.1
Webb, A.C.2
Rosenwasser, L.J.3
-
84
-
-
0022364132
-
Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs
-
March CJ, Mosley B, Larsen A, et al. Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs. Nature. 1985;315:641-647.
-
(1985)
Nature
, vol.315
, pp. 641-647
-
-
March, C.J.1
Mosley, B.2
Larsen, A.3
-
85
-
-
15844367093
-
Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein
-
Ushio S, Namba M, Okura T, et al. Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein. J Immunol. 1996;156:4274-4279.
-
(1996)
J Immunol
, vol.156
, pp. 4274-4279
-
-
Ushio, S.1
Namba, M.2
Okura, T.3
-
86
-
-
0028845730
-
Cloning of a new cytokine that induces IFN-gamma production by T cells
-
Okamura H, Tsutsi H, Komatsu T, et al. Cloning of a new cytokine that induces IFN-gamma production by T cells. Nature. 1995;378:88-91.
-
(1995)
Nature
, vol.378
, pp. 88-91
-
-
Okamura, H.1
Tsutsi, H.2
Komatsu, T.3
-
87
-
-
15644369352
-
Activation of interferon-gamma inducing factor mediated by interleukin-1 beta converting enzyme
-
Gu Y, Kuida K, Tsutsui H, et al. Activation of interferon-gamma inducing factor mediated by interleukin-1 beta converting enzyme. Science. 1997;275:206-209.
-
(1997)
Science
, vol.275
, pp. 206-209
-
-
Gu, Y.1
Kuida, K.2
Tsutsui, H.3
-
88
-
-
84883790050
-
Cytoplasmic LPS activates caspase-11: Implications in TLR4-independent endotoxic shock
-
Hagar JA, Powell DA, Aachoui Y, Ernst RK, Miao EA. Cytoplasmic LPS activates caspase-11: Implications in TLR4-independent endotoxic shock. Science. 2013;341:1250-1253.
-
(2013)
Science
, vol.341
, pp. 1250-1253
-
-
Hagar, J.A.1
Powell, D.A.2
Aachoui, Y.3
Ernst, R.K.4
Miao, E.A.5
-
89
-
-
84883775365
-
Noncanonical inflammasome activation by intracellular LPS independent of TLR4
-
Kayagaki N, Wong MT, Stowe IB, et al. Noncanonical inflammasome activation by intracellular LPS independent of TLR4. Science. 2013;341:1246-1249.
-
(2013)
Science
, vol.341
, pp. 1246-1249
-
-
Kayagaki, N.1
Wong, M.T.2
Stowe, I.B.3
-
90
-
-
84906571225
-
Inflammatory caspases are innate immune receptors for intracellular LPS
-
Shi J, Zhao Y, Wang Y, et al. Inflammatory caspases are innate immune receptors for intracellular LPS. Nature. 2014;514:187-192.
-
(2014)
Nature
, vol.514
, pp. 187-192
-
-
Shi, J.1
Zhao, Y.2
Wang, Y.3
-
91
-
-
7144255525
-
Enzymatic activity of two caspases related to interleukin-1beta-converting enzyme
-
Fassy F, Krebs O, Rey H, et al. Enzymatic activity of two caspases related to interleukin-1beta-converting enzyme. Eur J Biochem. 1998;253:76-83.
-
(1998)
Eur J Biochem
, vol.253
, pp. 76-83
-
-
Fassy, F.1
Krebs, O.2
Rey, H.3
-
92
-
-
84911992879
-
Noncanonical inflammasome activation of caspase-4/caspase-11 mediates epithelial defenses against enteric bacterial pathogens
-
Knodler LA, Crowley SM, Sham HP, et al. Noncanonical inflammasome activation of caspase-4/caspase-11 mediates epithelial defenses against enteric bacterial pathogens. Cell Host Microbe. 2014;16:249-256.
-
(2014)
Cell Host Microbe
, vol.16
, pp. 249-256
-
-
Knodler, L.A.1
Crowley, S.M.2
Sham, H.P.3
-
93
-
-
0029808205
-
Identification and characterization of Ich-3, a member of the interleukin-1beta converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE
-
Wang S, Miura M, Jung Y, et al. Identification and characterization of Ich-3, a member of the interleukin-1beta converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE. J Biol Chem. 1996;271:20580-20587.
-
(1996)
J Biol Chem
, vol.271
, pp. 20580-20587
-
-
Wang, S.1
Miura, M.2
Jung, Y.3
-
94
-
-
77951805919
-
Inflammatory stimuli regulate caspase substrate profiles
-
Agard NJ, Maltby D, Wells JA. Inflammatory stimuli regulate caspase substrate profiles. Mol Cell Proteomics. 2010;9:880-893.
-
(2010)
Mol Cell Proteomics
, vol.9
, pp. 880-893
-
-
Agard, N.J.1
Maltby, D.2
Wells, J.A.3
-
95
-
-
84943200249
-
Caspase-11 activates a canonical NLRP3 inflammasome by promoting K(+) efflux
-
Ruhl S, Broz P. Caspase-11 activates a canonical NLRP3 inflammasome by promoting K(+) efflux. Eur J Immunol. 2015;45:2927-2936.
-
(2015)
Eur J Immunol
, vol.45
, pp. 2927-2936
-
-
Ruhl, S.1
Broz, P.2
-
96
-
-
84934938651
-
Loss of conserved Gsdma3 self-regulation causes autophagy and cell death
-
Shi P, Tang A, Xian L, et al. Loss of conserved Gsdma3 self-regulation causes autophagy and cell death. Biochem J. 2015;468:325-336.
-
(2015)
Biochem J
, vol.468
, pp. 325-336
-
-
Shi, P.1
Tang, A.2
Xian, L.3
-
97
-
-
84935031669
-
N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting
-
Lin PH, Lin HY, Kuo CC, Yang LT. N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting. J Biomed Sci. 2015;22:44.
-
(2015)
J Biomed Sci
, vol.22
, pp. 44
-
-
Lin, P.H.1
Lin, H.Y.2
Kuo, C.C.3
Yang, L.T.4
-
98
-
-
85008419254
-
Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death
-
Rogers C, Fernandes-Alnemri T, Mayes L, Alnemri D, Cingolani G, Alnemri ES. Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death. Nat Commun. 2017;8:14128.
-
(2017)
Nat Commun
, vol.8
, pp. 14128
-
-
Rogers, C.1
Fernandes-Alnemri, T.2
Mayes, L.3
Alnemri, D.4
Cingolani, G.5
Alnemri, E.S.6
-
99
-
-
33746583965
-
Caspase-1-mediated activation of interleukin-1beta (IL-1beta) and IL-18 contributes to innate immune defenses against Salmonella enterica serovar Typhimurium infection
-
Raupach B, Peuschel SK, Monack DM, Zychlinsky A. Caspase-1-mediated activation of interleukin-1beta (IL-1beta) and IL-18 contributes to innate immune defenses against Salmonella enterica serovar Typhimurium infection. Infect Immun. 2006;74:4922-4926.
-
(2006)
Infect Immun
, vol.74
, pp. 4922-4926
-
-
Raupach, B.1
Peuschel, S.K.2
Monack, D.M.3
Zychlinsky, A.4
-
100
-
-
84859911615
-
NLRC4-driven production of IL-1beta discriminates between pathogenic and commensal bacteria and promotes host intestinal defense
-
Franchi L, Kamada N, Nakamura Y, et al. NLRC4-driven production of IL-1beta discriminates between pathogenic and commensal bacteria and promotes host intestinal defense. Nat Immunol. 2012;13:449-456.
-
(2012)
Nat Immunol
, vol.13
, pp. 449-456
-
-
Franchi, L.1
Kamada, N.2
Nakamura, Y.3
-
101
-
-
33745012076
-
Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis
-
Lara-Tejero M, Sutterwala FS, Ogura Y, et al. Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis. J Exp Med. 2006;203:1407-1412.
-
(2006)
J Exp Med
, vol.203
, pp. 1407-1412
-
-
Lara-Tejero, M.1
Sutterwala, F.S.2
Ogura, Y.3
-
102
-
-
84867333450
-
Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1
-
Broz P, Ruby T, Belhocine K, et al. Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1. Nature. 2012;490:288-291.
-
(2012)
Nature
, vol.490
, pp. 288-291
-
-
Broz, P.1
Ruby, T.2
Belhocine, K.3
-
103
-
-
84901008921
-
Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex
-
Man SM, Hopkins LJ, Nugent E, et al. Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex. Proc Natl Acad Sci USA. 2014;111:7403-7408.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 7403-7408
-
-
Man, S.M.1
Hopkins, L.J.2
Nugent, E.3
-
104
-
-
84874189388
-
Caspase-11 protects against bacteria that escape the vacuole
-
Aachoui Y, Leaf IA, Hagar JA, et al. Caspase-11 protects against bacteria that escape the vacuole. Science. 2013;339:975-978.
-
(2013)
Science
, vol.339
, pp. 975-978
-
-
Aachoui, Y.1
Leaf, I.A.2
Hagar, J.A.3
-
105
-
-
20144389060
-
Identification and functional characterization of chicken toll-like receptor 5 reveals a fundamental role in the biology of infection with Salmonella enterica serovar typhimurium
-
Iqbal M, Philbin VJ, Withanage GS, et al. Identification and functional characterization of chicken toll-like receptor 5 reveals a fundamental role in the biology of infection with Salmonella enterica serovar typhimurium. Infect Immun. 2005;73:2344-2350.
-
(2005)
Infect Immun
, vol.73
, pp. 2344-2350
-
-
Iqbal, M.1
Philbin, V.J.2
Withanage, G.S.3
-
106
-
-
0034874499
-
Absence of all components of the flagellar export and synthesis machinery differentially alters virulence of Salmonella enterica serovar Typhimurium in models of typhoid fever, survival in macrophages, tissue culture invasiveness, and calf enterocolitis
-
Schmitt CK, Ikeda JS, Darnell SC, et al. Absence of all components of the flagellar export and synthesis machinery differentially alters virulence of Salmonella enterica serovar Typhimurium in models of typhoid fever, survival in macrophages, tissue culture invasiveness, and calf enterocolitis. Infect Immun. 2001;69:5619-5625.
-
(2001)
Infect Immun
, vol.69
, pp. 5619-5625
-
-
Schmitt, C.K.1
Ikeda, J.S.2
Darnell, S.C.3
-
107
-
-
3042546218
-
Flagella and chemotaxis are required for efficient induction of Salmonella enterica serovar Typhimurium colitis in streptomycin-pretreated mice
-
Stecher B, Hapfelmeier S, Muller C, Kremer M, Stallmach T, Hardt WD. Flagella and chemotaxis are required for efficient induction of Salmonella enterica serovar Typhimurium colitis in streptomycin-pretreated mice. Infect Immun. 2004;72:4138-4150.
-
(2004)
Infect Immun
, vol.72
, pp. 4138-4150
-
-
Stecher, B.1
Hapfelmeier, S.2
Muller, C.3
Kremer, M.4
Stallmach, T.5
Hardt, W.D.6
-
108
-
-
34248385381
-
Flagellin suppresses epithelial apoptosis and limits disease during enteric infection
-
Vijay-Kumar M, Wu H, Jones R, et al. Flagellin suppresses epithelial apoptosis and limits disease during enteric infection. Am J Pathol. 2006;169:1686-1700.
-
(2006)
Am J Pathol
, vol.169
, pp. 1686-1700
-
-
Vijay-Kumar, M.1
Wu, H.2
Jones, R.3
-
109
-
-
84855493990
-
Regulation of phenotypic heterogeneity permits Salmonella evasion of the host caspase-1 inflammatory response
-
Stewart MK, Cummings LA, Johnson ML, Berezow AB, Cookson BT. Regulation of phenotypic heterogeneity permits Salmonella evasion of the host caspase-1 inflammatory response. Proc Natl Acad Sci USA. 2011;108:20742-20747.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 20742-20747
-
-
Stewart, M.K.1
Cummings, L.A.2
Johnson, M.L.3
Berezow, A.B.4
Cookson, B.T.5
-
110
-
-
78449269290
-
Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria
-
Miao EA, Leaf IA, Treuting PM, et al. Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria. Nat Immunol. 2010;11:1136-1142.
-
(2010)
Nat Immunol
, vol.11
, pp. 1136-1142
-
-
Miao, E.A.1
Leaf, I.A.2
Treuting, P.M.3
-
111
-
-
84908024529
-
Epithelium-intrinsic NAIP/NLRC4 inflammasome drives infected enterocyte expulsion to restrict Salmonella replication in the intestinal mucosa
-
Sellin ME, Muller AA, Felmy B, et al. Epithelium-intrinsic NAIP/NLRC4 inflammasome drives infected enterocyte expulsion to restrict Salmonella replication in the intestinal mucosa. Cell Host Microbe. 2014;16:237-248.
-
(2014)
Cell Host Microbe
, vol.16
, pp. 237-248
-
-
Sellin, M.E.1
Muller, A.A.2
Felmy, B.3
-
112
-
-
84988813074
-
Pyroptosis triggers pore-induced intracellular traps (PITs) that capture bacteria and lead to their clearance by efferocytosis
-
Jorgensen I, Zhang Y, Krantz BA, Miao EA. Pyroptosis triggers pore-induced intracellular traps (PITs) that capture bacteria and lead to their clearance by efferocytosis. J Exp Med. 2016;213:2113-2128.
-
(2016)
J Exp Med
, vol.213
, pp. 2113-2128
-
-
Jorgensen, I.1
Zhang, Y.2
Krantz, B.A.3
Miao, E.A.4
-
113
-
-
84904792729
-
The neutrophil NLRC4 inflammasome selectively promotes IL-1beta maturation without pyroptosis during acute Salmonella challenge
-
Chen KW, Gross CJ, Sotomayor FV, et al. The neutrophil NLRC4 inflammasome selectively promotes IL-1beta maturation without pyroptosis during acute Salmonella challenge. Cell Rep. 2014;8:570-582.
-
(2014)
Cell Rep
, vol.8
, pp. 570-582
-
-
Chen, K.W.1
Gross, C.J.2
Sotomayor, F.V.3
-
114
-
-
85019864393
-
Neutrophil pyroptosis mediates pathology of P. aeruginosa lung infection in the absence of the NADPH oxidase NOX2
-
Ryu JC, Kim MJ, Kwon Y, et al. Neutrophil pyroptosis mediates pathology of P. aeruginosa lung infection in the absence of the NADPH oxidase NOX2. Mucosal Immunol. 2016; https://doi.org/10.1038/mi.2016.73.
-
(2016)
Mucosal Immunol
-
-
Ryu, J.C.1
Kim, M.J.2
Kwon, Y.3
-
115
-
-
84947416929
-
Inflammasomes coordinate pyroptosis and natural killer cell cytotoxicity to clear infection by a ubiquitous environmental bacterium
-
Maltez VI, Tubbs AL, Cook KD, et al. Inflammasomes coordinate pyroptosis and natural killer cell cytotoxicity to clear infection by a ubiquitous environmental bacterium. Immunity. 2015;43:987-997.
-
(2015)
Immunity
, vol.43
, pp. 987-997
-
-
Maltez, V.I.1
Tubbs, A.L.2
Cook, K.D.3
-
116
-
-
84941317034
-
Canonical inflammasomes drive IFN-gamma to prime caspase-11 in defense against a cytosol-invasive bacterium
-
Aachoui Y, Kajiwara Y, Leaf IA, et al. Canonical inflammasomes drive IFN-gamma to prime caspase-11 in defense against a cytosol-invasive bacterium. Cell Host Microbe. 2015;18:320-332.
-
(2015)
Cell Host Microbe
, vol.18
, pp. 320-332
-
-
Aachoui, Y.1
Kajiwara, Y.2
Leaf, I.A.3
-
117
-
-
84875850500
-
Activation of inflammasome signaling mediates pathology of acute P. aeruginosa pneumonia
-
Cohen TS, Prince AS. Activation of inflammasome signaling mediates pathology of acute P. aeruginosa pneumonia. J Clin Invest. 2013;123:1630-1637.
-
(2013)
J Clin Invest
, vol.123
, pp. 1630-1637
-
-
Cohen, T.S.1
Prince, A.S.2
-
118
-
-
84897447822
-
Pseudomonas aeruginosa type-3 secretion system dampens host defense by exploiting the NLRC4-coupled inflammasome
-
Faure E, Mear JB, Faure K, et al. Pseudomonas aeruginosa type-3 secretion system dampens host defense by exploiting the NLRC4-coupled inflammasome. Am J Respir Crit Care Med. 2014;189:799-811.
-
(2014)
Am J Respir Crit Care Med
, vol.189
, pp. 799-811
-
-
Faure, E.1
Mear, J.B.2
Faure, K.3
-
119
-
-
85009127185
-
Listeria monocytogenes-induced cell death inhibits the generation of cell-mediated immunity
-
Theisen E, Sauer JD. Listeria monocytogenes-induced cell death inhibits the generation of cell-mediated immunity. Infect Immun. 2017;85:e00733-16.
-
(2017)
Infect Immun
, vol.85
, pp. 716-733
-
-
Theisen, E.1
Sauer, J.D.2
-
120
-
-
84943199941
-
NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5
-
Baker PJ, Boucher D, Bierschenk D, et al. NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5. Eur J Immunol. 2015;45:2918-2926.
-
(2015)
Eur J Immunol
, vol.45
, pp. 2918-2926
-
-
Baker, P.J.1
Boucher, D.2
Bierschenk, D.3
-
121
-
-
84943198707
-
Caspase-4 mediates non-canonical activation of the NLRP3 inflammasome in human myeloid cells
-
Schmid-Burgk JL, Gaidt MM, Schmidt T, Ebert TS, Bartok E, Hornung V. Caspase-4 mediates non-canonical activation of the NLRP3 inflammasome in human myeloid cells. Eur J Immunol. 2015;45:2911-2917.
-
(2015)
Eur J Immunol
, vol.45
, pp. 2911-2917
-
-
Schmid-Burgk, J.L.1
Gaidt, M.M.2
Schmidt, T.3
Ebert, T.S.4
Bartok, E.5
Hornung, V.6
-
122
-
-
84903555072
-
Gama Sosa MA, Elder G, Bozdagi O, Buxbaum JD. A critical role for human caspase-4 in endotoxin sensitivity
-
Kajiwara Y, Schiff T, Voloudakis G. Gama Sosa MA, Elder G, Bozdagi O, Buxbaum JD. A critical role for human caspase-4 in endotoxin sensitivity. J Immunol. 2014;193:335-343.
-
(2014)
J Immunol
, vol.193
, pp. 335-343
-
-
Kajiwara, Y.1
Schiff, T.2
Voloudakis, G.3
-
123
-
-
84930225289
-
Human caspase-4 mediates noncanonical inflammasome activation against gram-negative bacterial pathogens
-
Casson CN, Yu J, Reyes VM, et al. Human caspase-4 mediates noncanonical inflammasome activation against gram-negative bacterial pathogens. Proc Natl Acad Sci USA. 2015;112:6688-6693.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. 6688-6693
-
-
Casson, C.N.1
Yu, J.2
Reyes, V.M.3
-
124
-
-
84945542875
-
Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes
-
Vigano E, Diamond CE, Spreafico R, Balachander A, Sobota RM, Mortellaro A. Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes. Nat Commun. 2015;6:8761.
-
(2015)
Nat Commun
, vol.6
, pp. 8761
-
-
Vigano, E.1
Diamond, C.E.2
Spreafico, R.3
Balachander, A.4
Sobota, R.M.5
Mortellaro, A.6
-
125
-
-
84864292536
-
Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization
-
Akhter A, Caution K, Abu Khweek A, et al. Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization. Immunity. 2012;37:35-47.
-
(2012)
Immunity
, vol.37
, pp. 35-47
-
-
Akhter, A.1
Caution, K.2
Abu Khweek, A.3
-
126
-
-
85019838573
-
Bacterial virulence factor inhibits caspase-4/11 activation in intestinal epithelial cells
-
Pallett MA, Crepin VF, Serafini N, et al. Bacterial virulence factor inhibits caspase-4/11 activation in intestinal epithelial cells. Mucosal Immunol. 2016; https://doi.org/10.1038/mi.2016.77.
-
(2016)
Mucosal Immunol
-
-
Pallett, M.A.1
Crepin, V.F.2
Serafini, N.3
-
127
-
-
84884137769
-
A type III effector antagonizes death receptor signalling during bacterial gut infection
-
Pearson JS, Giogha C, Ong SY, et al. A type III effector antagonizes death receptor signalling during bacterial gut infection. Nature. 2013;501:247-251.
-
(2013)
Nature
, vol.501
, pp. 247-251
-
-
Pearson, J.S.1
Giogha, C.2
Ong, S.Y.3
-
128
-
-
84884140839
-
Pathogen blocks host death receptor signalling by arginine GlcNAcylation of death domains
-
Li S, Zhang L, Yao Q, et al. Pathogen blocks host death receptor signalling by arginine GlcNAcylation of death domains. Nature. 2013;501:242-246.
-
(2013)
Nature
, vol.501
, pp. 242-246
-
-
Li, S.1
Zhang, L.2
Yao, Q.3
-
129
-
-
77649260428
-
NleH effectors interact with Bax inhibitor-1 to block apoptosis during enteropathogenic Escherichia coli infection
-
Hemrajani C, Berger CN, Robinson KS, Marches O, Mousnier A, Frankel G. NleH effectors interact with Bax inhibitor-1 to block apoptosis during enteropathogenic Escherichia coli infection. Proc Natl Acad Sci USA. 2010;107:3129-3134.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 3129-3134
-
-
Hemrajani, C.1
Berger, C.N.2
Robinson, K.S.3
Marches, O.4
Mousnier, A.5
Frankel, G.6
-
130
-
-
33846024748
-
Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf
-
Amer A, Franchi L, Kanneganti TD, et al. Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf. J Biol Chem. 2006;281:35217-35223.
-
(2006)
J Biol Chem
, vol.281
, pp. 35217-35223
-
-
Amer, A.1
Franchi, L.2
Kanneganti, T.D.3
-
131
-
-
84878245034
-
Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function
-
Sokolovska A, Becker CE, Ip WK, et al. Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function. Nat Immunol. 2013;14:543-553.
-
(2013)
Nat Immunol
, vol.14
, pp. 543-553
-
-
Sokolovska, A.1
Becker, C.E.2
Ip, W.K.3
-
132
-
-
84916215920
-
Actin polymerization as a key innate immune effector mechanism to control Salmonella infection
-
Man SM, Ekpenyong A, Tourlomousis P, et al. Actin polymerization as a key innate immune effector mechanism to control Salmonella infection. Proc Natl Acad Sci USA. 2014;111:17588-17593.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 17588-17593
-
-
Man, S.M.1
Ekpenyong, A.2
Tourlomousis, P.3
-
133
-
-
84994274907
-
Growth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death
-
Thurston TL, Matthews SA, Jennings E, et al. Growth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death. Nat Commun. 2016;7:13292.
-
(2016)
Nat Commun
, vol.7
, pp. 13292
-
-
Thurston, T.L.1
Matthews, S.A.2
Jennings, E.3
-
134
-
-
84956825823
-
AIM2 inflammasome in infection, cancer, and autoimmunity: Role in DNA sensing, inflammation, and innate immunity
-
Man SM, Karki R, Kanneganti TD. AIM2 inflammasome in infection, cancer, and autoimmunity: Role in DNA sensing, inflammation, and innate immunity. Eur J Immunol. 2016;46:269-280.
-
(2016)
Eur J Immunol
, vol.46
, pp. 269-280
-
-
Man, S.M.1
Karki, R.2
Kanneganti, T.D.3
-
135
-
-
84881627553
-
The expanding role of NLRs in antiviral immunity
-
Lupfer C, Kanneganti TD. The expanding role of NLRs in antiviral immunity. Immunol Rev. 2013;255:13-24.
-
(2013)
Immunol Rev
, vol.255
, pp. 13-24
-
-
Lupfer, C.1
Kanneganti, T.D.2
-
136
-
-
84888002403
-
IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication
-
Jakobsen MR, Bak RO, Andersen A, et al. IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication. Proc Natl Acad Sci USA. 2013;110:E4571-E4580.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 4571-4580
-
-
Jakobsen, M.R.1
Bak, R.O.2
Andersen, A.3
-
137
-
-
84892946076
-
IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV
-
Monroe KM, Yang Z, Johnson JR, et al. IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV. Science. 2014;343:428-432.
-
(2014)
Science
, vol.343
, pp. 428-432
-
-
Monroe, K.M.1
Yang, Z.2
Johnson, J.R.3
-
138
-
-
84892739389
-
Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection
-
Doitsh G, Galloway NL, Geng X, et al. Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection. Nature. 2014;505:509-514.
-
(2014)
Nature
, vol.505
, pp. 509-514
-
-
Doitsh, G.1
Galloway, N.L.2
Geng, X.3
-
139
-
-
84941182496
-
Cell-to-cell transmission of HIV-1 is required to trigger pyroptotic death of lymphoid-tissue-derived CD4 T cells
-
Galloway NL, Doitsh G, Monroe KM, et al. Cell-to-cell transmission of HIV-1 is required to trigger pyroptotic death of lymphoid-tissue-derived CD4 T cells. Cell Rep. 2015;12:1555-1563.
-
(2015)
Cell Rep
, vol.12
, pp. 1555-1563
-
-
Galloway, N.L.1
Doitsh, G.2
Monroe, K.M.3
-
140
-
-
84944196767
-
Blood-derived CD4 T cells naturally resist pyroptosis during abortive HIV-1 infection
-
Munoz-Arias I, Doitsh G, Yang Z, Sowinski S, Ruelas D, Greene WC. Blood-derived CD4 T cells naturally resist pyroptosis during abortive HIV-1 infection. Cell Host Microbe. 2015;18:463-470.
-
(2015)
Cell Host Microbe
, vol.18
, pp. 463-470
-
-
Munoz-Arias, I.1
Doitsh, G.2
Yang, Z.3
Sowinski, S.4
Ruelas, D.5
Greene, W.C.6
-
141
-
-
85006086042
-
Hepatitis C virus infection of cultured human hepatoma cells causes apoptosis and pyroptosis in both infected and bystander cells
-
Kofahi HM, Taylor NG, Hirasawa K, Grant MD, Russell RS. Hepatitis C virus infection of cultured human hepatoma cells causes apoptosis and pyroptosis in both infected and bystander cells. Sci Rep. 2016;6:37433.
-
(2016)
Sci Rep
, vol.6
, pp. 37433
-
-
Kofahi, H.M.1
Taylor, N.G.2
Hirasawa, K.3
Grant, M.D.4
Russell, R.S.5
-
142
-
-
84870793191
-
IL-1beta signaling promotes CNS-intrinsic immune control of West Nile virus infection
-
Ramos HJ, Lanteri MC, Blahnik G, et al. IL-1beta signaling promotes CNS-intrinsic immune control of West Nile virus infection. PLoS Pathog. 2012;8:e1003039.
-
(2012)
PLoS Pathog
, vol.8
-
-
Ramos, H.J.1
Lanteri, M.C.2
Blahnik, G.3
-
143
-
-
64049096334
-
The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1
-
Thomas PG, Dash P, Aldridge JR Jr, et al. The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1. Immunity. 2009;30:566-575.
-
(2009)
Immunity
, vol.30
, pp. 566-575
-
-
Thomas, P.G.1
Dash, P.2
Aldridge, J.R.3
-
144
-
-
64049111768
-
The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA
-
Allen IC, Scull MA, Moore CB, et al. The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity. 2009;30:556-565.
-
(2009)
Immunity
, vol.30
, pp. 556-565
-
-
Allen, I.C.1
Scull, M.A.2
Moore, C.B.3
-
145
-
-
33846014297
-
Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA
-
Kanneganti TD, Body-Malapel M, Amer A, et al. Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA. J Biol Chem. 2006;281:36560-36568.
-
(2006)
J Biol Chem
, vol.281
, pp. 36560-36568
-
-
Kanneganti, T.D.1
Body-Malapel, M.2
Amer, A.3
-
146
-
-
85022040336
-
ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways
-
Kuriakose T, Man SM, Malireddi RK, et al. ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways. Sci Immunol. 2016;1:pii:aag2045.
-
(2016)
Sci Immunol
, vol.1
-
-
Kuriakose, T.1
Man, S.M.2
Malireddi, R.K.3
-
147
-
-
60549112774
-
Inflammasome recognition of influenza virus is essential for adaptive immune responses
-
Ichinohe T, Lee HK, Ogura Y, Flavell R, Iwasaki A. Inflammasome recognition of influenza virus is essential for adaptive immune responses. J Exp Med. 2009;206:79-87.
-
(2009)
J Exp Med
, vol.206
, pp. 79-87
-
-
Ichinohe, T.1
Lee, H.K.2
Ogura, Y.3
Flavell, R.4
Iwasaki, A.5
-
148
-
-
84964798222
-
Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease
-
Pillai PS, Molony RD, Martinod K, et al. Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease. Science. 2016;352:463-466.
-
(2016)
Science
, vol.352
, pp. 463-466
-
-
Pillai, P.S.1
Molony, R.D.2
Martinod, K.3
-
149
-
-
84926164932
-
Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against Aspergillus infection
-
Karki R, Man SM, Malireddi RK, et al. Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against Aspergillus infection. Cell Host Microbe. 2015;17:357-368.
-
(2015)
Cell Host Microbe
, vol.17
, pp. 357-368
-
-
Karki, R.1
Man, S.M.2
Malireddi, R.K.3
-
150
-
-
77954958602
-
Aspergillus fumigatus stimulates the NLRP3 inflammasome through a pathway requiring ROS production and the Syk tyrosine kinase
-
Said-Sadier N, Padilla E, Langsley G, Ojcius DM. Aspergillus fumigatus stimulates the NLRP3 inflammasome through a pathway requiring ROS production and the Syk tyrosine kinase. PLoS ONE. 2010;5:e10008.
-
(2010)
PLoS ONE
, vol.5
-
-
Said-Sadier, N.1
Padilla, E.2
Langsley, G.3
Ojcius, D.M.4
-
151
-
-
84951933158
-
Caspase-11 and caspase-1 differentially modulate actin polymerization via RhoA and Slingshot proteins to promote bacterial clearance
-
Caution K, Gavrilin MA, Tazi M, et al. Caspase-11 and caspase-1 differentially modulate actin polymerization via RhoA and Slingshot proteins to promote bacterial clearance. Sci Rep-UK. 2015; https://doi.org/10.1038/srep18479.
-
(2015)
Sci Rep-UK
-
-
Caution, K.1
Gavrilin, M.A.2
Tazi, M.3
-
152
-
-
84964434465
-
An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells
-
Zanoni I, Tan Y, Di Gioia M, et al. An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells. Science. 2016;352:1232-1236.
-
(2016)
Science
, vol.352
, pp. 1232-1236
-
-
Zanoni, I.1
Tan, Y.2
Di Gioia, M.3
-
153
-
-
79960714886
-
The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis
-
van de Veerdonk FL, Joosten LA, Shaw PJ, et al. The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis. Eur J Immunol. 2011;41:2260-2268.
-
(2011)
Eur J Immunol
, vol.41
, pp. 2260-2268
-
-
van de Veerdonk, F.L.1
Joosten, L.A.2
Shaw, P.J.3
-
154
-
-
65549154784
-
An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans
-
Hise AG, Tomalka J, Ganesan S, et al. An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans. Cell Host Microbe. 2009;5:487-497.
-
(2009)
Cell Host Microbe
, vol.5
, pp. 487-497
-
-
Hise, A.G.1
Tomalka, J.2
Ganesan, S.3
-
155
-
-
0033863092
-
Interleukin 18 restores defective Th1 immunity to Candida albicans in caspase 1-deficient mice
-
Mencacci A, Bacci A, Cenci E, et al. Interleukin 18 restores defective Th1 immunity to Candida albicans in caspase 1-deficient mice. Infect Immun. 2000;68:5126-5131.
-
(2000)
Infect Immun
, vol.68
, pp. 5126-5131
-
-
Mencacci, A.1
Bacci, A.2
Cenci, E.3
-
156
-
-
84928485670
-
IL-18 triggered by the Nlrp3 inflammasome induces host innate resistance in a pulmonary model of fungal infection
-
Ketelut-Carneiro N, Silva GK, Rocha FA, et al. IL-18 triggered by the Nlrp3 inflammasome induces host innate resistance in a pulmonary model of fungal infection. J Immunol. 2015;194:4507-4517.
-
(2015)
J Immunol
, vol.194
, pp. 4507-4517
-
-
Ketelut-Carneiro, N.1
Silva, G.K.2
Rocha, F.A.3
-
157
-
-
84899731243
-
The pathogen Candida albicans hijacks pyroptosis for escape from macrophages
-
Uwamahoro N, Verma-Gaur J, Shen HH, et al. The pathogen Candida albicans hijacks pyroptosis for escape from macrophages. MBio. 2014;5:e00003-e00014.
-
(2014)
MBio
, vol.5
, pp. 3-14
-
-
Uwamahoro, N.1
Verma-Gaur, J.2
Shen, H.H.3
-
158
-
-
85011068475
-
Phagosomal neutralization by the fungal pathogen Candida albicans induces macrophage pyroptosis
-
Vylkova S, Lorenz MC. Phagosomal neutralization by the fungal pathogen Candida albicans induces macrophage pyroptosis. Infect Immun. 2017;85:e00832-16.
-
(2017)
Infect Immun
, vol.85
, pp. 816-832
-
-
Vylkova, S.1
Lorenz, M.C.2
-
159
-
-
84880255426
-
Inflammasome-derived IL-1beta production induces nitric oxide-mediated resistance to Leishmania
-
Lima-Junior DS, Costa DL, Carregaro V, et al. Inflammasome-derived IL-1beta production induces nitric oxide-mediated resistance to Leishmania. Nat Med. 2013;19:909-915.
-
(2013)
Nat Med
, vol.19
, pp. 909-915
-
-
Lima-Junior, D.S.1
Costa, D.L.2
Carregaro, V.3
-
160
-
-
84924087828
-
An NLRP3 inflammasome-triggered Th2-biased adaptive immune response promotes leishmaniasis
-
Gurung P, Karki R, Vogel P, et al. An NLRP3 inflammasome-triggered Th2-biased adaptive immune response promotes leishmaniasis. J Clin Invest. 2015;125:1329-1338.
-
(2015)
J Clin Invest
, vol.125
, pp. 1329-1338
-
-
Gurung, P.1
Karki, R.2
Vogel, P.3
-
161
-
-
84903369192
-
Dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii
-
Gorfu G, Cirelli KM, Melo MB, et al. Dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii. MBio. 2014;5:e01117-13.
-
(2014)
MBio
, vol.5
, pp. 1113-1117
-
-
Gorfu, G.1
Cirelli, K.M.2
Melo, M.B.3
-
162
-
-
84884230791
-
Apoptosis-associated speck-like protein containing a caspase recruitment domain inflammasomes mediate IL-1beta response and host resistance to Trypanosoma cruzi infection
-
Silva GK, Costa RS, Silveira TN, et al. Apoptosis-associated speck-like protein containing a caspase recruitment domain inflammasomes mediate IL-1beta response and host resistance to Trypanosoma cruzi infection. J Immunol. 2013;191:3373-3383.
-
(2013)
J Immunol
, vol.191
, pp. 3373-3383
-
-
Silva, G.K.1
Costa, R.S.2
Silveira, T.N.3
-
163
-
-
84887269515
-
NLRP3 controls Trypanosoma cruzi infection through a caspase-1-dependent IL-1R-independent NO production
-
Goncalves VM, Matteucci KC, Buzzo CL, et al. NLRP3 controls Trypanosoma cruzi infection through a caspase-1-dependent IL-1R-independent NO production. PLoS Negl Trop Dis. 2013;7:e2469.
-
(2013)
PLoS Negl Trop Dis
, vol.7
-
-
Goncalves, V.M.1
Matteucci, K.C.2
Buzzo, C.L.3
-
164
-
-
84976558046
-
Caspase-11 modulates inflammation and attenuates Toxoplasma gondii pathogenesis
-
Coutermarsh-Ott SL, Doran JT, Campbell C, Williams TM, Lindsay DS, Allen IC. Caspase-11 modulates inflammation and attenuates Toxoplasma gondii pathogenesis. Mediators Inflamm. 2016;2016:9848263.
-
(2016)
Mediators Inflamm
, vol.2016
, pp. 9848263
-
-
Coutermarsh-Ott, S.L.1
Doran, J.T.2
Campbell, C.3
Williams, T.M.4
Lindsay, D.S.5
Allen, I.C.6
-
165
-
-
85008476077
-
Interferon-inducible guanylate-binding proteins at the interface of cell-autonomous immunity and inflammasome activation
-
Man SM, Place DE, Kuriakose T, Kanneganti TD. Interferon-inducible guanylate-binding proteins at the interface of cell-autonomous immunity and inflammasome activation. J Leukoc Biol. 2016;101:143-150.
-
(2016)
J Leukoc Biol
, vol.101
, pp. 143-150
-
-
Man, S.M.1
Place, D.E.2
Kuriakose, T.3
Kanneganti, T.D.4
-
166
-
-
84867241369
-
Toll or interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-beta (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4) protein- and Nlrp3 inflammasome-mediated host defense against enteropathogens
-
Gurung P, Malireddi RK, Anand PK, et al. Toll or interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-beta (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4) protein- and Nlrp3 inflammasome-mediated host defense against enteropathogens. J Biol Chem. 2012;287:34474-34483.
-
(2012)
J Biol Chem
, vol.287
, pp. 34474-34483
-
-
Gurung, P.1
Malireddi, R.K.2
Anand, P.K.3
-
167
-
-
84864600268
-
TRIF Licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria
-
Rathinam VA, Vanaja SK, Waggoner L, et al. TRIF Licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria. Cell. 2012;150:606-619.
-
(2012)
Cell
, vol.150
, pp. 606-619
-
-
Rathinam, V.A.1
Vanaja, S.K.2
Waggoner, L.3
-
168
-
-
0036829675
-
Caspase-11 gene expression in response to lipopolysaccharide and interferon-gamma requires nuclear factor-kappa B and signal transducer and activator of transcription (STAT) 1
-
Schauvliege R, Vanrobaeys J, Schotte P, Beyaert R. Caspase-11 gene expression in response to lipopolysaccharide and interferon-gamma requires nuclear factor-kappa B and signal transducer and activator of transcription (STAT) 1. J Biol Chem. 2002;277:41624-41630.
-
(2002)
J Biol Chem
, vol.277
, pp. 41624-41630
-
-
Schauvliege, R.1
Vanrobaeys, J.2
Schotte, P.3
Beyaert, R.4
-
169
-
-
79959242498
-
Detection of prokaryotic mRNA signifies microbial viability and promotes immunity
-
Sander LE, Davis MJ, Boekschoten MV, et al. Detection of prokaryotic mRNA signifies microbial viability and promotes immunity. Nature. 2011;474:385-389.
-
(2011)
Nature
, vol.474
, pp. 385-389
-
-
Sander, L.E.1
Davis, M.J.2
Boekschoten, M.V.3
-
170
-
-
84907584408
-
Reactive oxygen species regulate caspase-11 expression and activation of the non-canonical NLRP3 inflammasome during enteric pathogen infection
-
Lupfer CR, Anand PK, Liu Z, et al. Reactive oxygen species regulate caspase-11 expression and activation of the non-canonical NLRP3 inflammasome during enteric pathogen infection. PLoS Pathog. 2014;10:e1004410.
-
(2014)
PLoS Pathog
, vol.10
-
-
Lupfer, C.R.1
Anand, P.K.2
Liu, Z.3
-
171
-
-
84994490206
-
Complement pathway amplifies caspase-11-dependent cell death and endotoxin-induced sepsis severity
-
Napier BA, Brubaker SW, Sweeney TE, et al. Complement pathway amplifies caspase-11-dependent cell death and endotoxin-induced sepsis severity. J Exp Med. 2016;213:2365-2382.
-
(2016)
J Exp Med
, vol.213
, pp. 2365-2382
-
-
Napier, B.A.1
Brubaker, S.W.2
Sweeney, T.E.3
-
172
-
-
84900564237
-
Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases
-
Meunier E, Dick MS, Dreier RF, et al. Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases. Nature. 2014;509:366-370.
-
(2014)
Nature
, vol.509
, pp. 366-370
-
-
Meunier, E.1
Dick, M.S.2
Dreier, R.F.3
-
173
-
-
84899098318
-
Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS
-
Pilla DM, Hagar JA, Haldar AK, et al. Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS. Proc Natl Acad Sci USA. 2014;111:6046-6051.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 6046-6051
-
-
Pilla, D.M.1
Hagar, J.A.2
Haldar, A.K.3
-
174
-
-
84949652170
-
Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages
-
Finethy R, Jorgensen I, Haldar AK, et al. Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages. Infect Immun. 2015;83:4740-4749.
-
(2015)
Infect Immun
, vol.83
, pp. 4740-4749
-
-
Finethy, R.1
Jorgensen, I.2
Haldar, A.K.3
-
175
-
-
84990856288
-
IRGB10 liberates bacterial ligands for sensing by the AIM2 and caspase-11-NLRP3 inflammasomes
-
e317
-
Man SM, Karki R, Sasai M, et al. IRGB10 liberates bacterial ligands for sensing by the AIM2 and caspase-11-NLRP3 inflammasomes. Cell. 2016;167:382-396 e317.
-
(2016)
Cell
, vol.167
, pp. 382-396
-
-
Man, S.M.1
Karki, R.2
Sasai, M.3
-
176
-
-
84964956157
-
Bacterial outer membrane vesicles mediate cytosolic localization of LPS and caspase-11 activation
-
Vanaja SK, Russo AJ, Behl B, et al. Bacterial outer membrane vesicles mediate cytosolic localization of LPS and caspase-11 activation. Cell. 2016;165:1106-1119.
-
(2016)
Cell
, vol.165
, pp. 1106-1119
-
-
Vanaja, S.K.1
Russo, A.J.2
Behl, B.3
-
177
-
-
84928545520
-
The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection
-
Man SM, Karki R, Malireddi RK, et al. The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection. Nat Immunol. 2015;16:467-475.
-
(2015)
Nat Immunol
, vol.16
, pp. 467-475
-
-
Man, S.M.1
Karki, R.2
Malireddi, R.K.3
-
178
-
-
84928538482
-
Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida
-
Meunier E, Wallet P, Dreier RF, et al. Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida. Nat Immunol. 2015;16:476-484.
-
(2015)
Nat Immunol
, vol.16
, pp. 476-484
-
-
Meunier, E.1
Wallet, P.2
Dreier, R.F.3
-
179
-
-
34249044447
-
Type I interferon signaling is required for activation of the inflammasome during Francisella infection
-
Henry T, Brotcke A, Weiss DS, Thompson LJ, Monack DM. Type I interferon signaling is required for activation of the inflammasome during Francisella infection. J Exp Med. 2007;204:987-994.
-
(2007)
J Exp Med
, vol.204
, pp. 987-994
-
-
Henry, T.1
Brotcke, A.2
Weiss, D.S.3
Thompson, L.J.4
Monack, D.M.5
-
180
-
-
77951263260
-
The AIM2 inflammasome is critical for innate immunity to Francisella tularensis
-
Fernandes-Alnemri T, Yu JW, Juliana C, et al. The AIM2 inflammasome is critical for innate immunity to Francisella tularensis. Nat Immunol. 2010;11:385-393.
-
(2010)
Nat Immunol
, vol.11
, pp. 385-393
-
-
Fernandes-Alnemri, T.1
Yu, J.W.2
Juliana, C.3
-
181
-
-
45549087455
-
Macrophage proinflammatory response to Francisella tularensis live vaccine strain requires coordination of multiple signaling pathways
-
Cole LE, Santiago A, Barry E, et al. Macrophage proinflammatory response to Francisella tularensis live vaccine strain requires coordination of multiple signaling pathways. J Immunol. 2008;180:6885-6891.
-
(2008)
J Immunol
, vol.180
, pp. 6885-6891
-
-
Cole, L.E.1
Santiago, A.2
Barry, E.3
-
182
-
-
77951269392
-
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
-
Rathinam VA, Jiang Z, Waggoner SN, et al. The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses. Nat Immunol. 2010;11:395-402.
-
(2010)
Nat Immunol
, vol.11
, pp. 395-402
-
-
Rathinam, V.A.1
Jiang, Z.2
Waggoner, S.N.3
-
183
-
-
77953116282
-
Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis
-
Jones JW, Kayagaki N, Broz P, et al. Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis. Proc Natl Acad Sci USA. 2010;107:9771-9776.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 9771-9776
-
-
Jones, J.W.1
Kayagaki, N.2
Broz, P.3
-
184
-
-
84925841637
-
cGAS and Ifi204 cooperate to produce type I IFNs in response to Francisella infection
-
Storek KM, Gertsvolf NA, Ohlson MB, Monack DM. cGAS and Ifi204 cooperate to produce type I IFNs in response to Francisella infection. J Immunol. 2015;194:3236-3245.
-
(2015)
J Immunol
, vol.194
, pp. 3236-3245
-
-
Storek, K.M.1
Gertsvolf, N.A.2
Ohlson, M.B.3
Monack, D.M.4
-
185
-
-
84994731750
-
DAI senses influenza A virus genomic RNA and activates RIPK3-dependent cell death
-
Thapa RJ, Ingram JP, Ragan KB, et al. DAI senses influenza A virus genomic RNA and activates RIPK3-dependent cell death. Cell Host Microbe. 2016;20:674-681.
-
(2016)
Cell Host Microbe
, vol.20
, pp. 674-681
-
-
Thapa, R.J.1
Ingram, J.P.2
Ragan, K.B.3
-
186
-
-
84978648026
-
RIPK3 activates parallel pathways of MLKL-driven necroptosis and FADD-mediated apoptosis to protect against influenza A virus
-
Nogusa S, Thapa RJ, Dillon CP, et al. RIPK3 activates parallel pathways of MLKL-driven necroptosis and FADD-mediated apoptosis to protect against influenza A virus. Cell Host Microbe. 2016;20:13-24.
-
(2016)
Cell Host Microbe
, vol.20
, pp. 13-24
-
-
Nogusa, S.1
Thapa, R.J.2
Dillon, C.P.3
-
187
-
-
84921486975
-
Protective role for caspase-11 during acute experimental murine colitis
-
Oficjalska K, Raverdeau M, Aviello G, et al. Protective role for caspase-11 during acute experimental murine colitis. J Immunol. 2014;194:1252-1260.
-
(2014)
J Immunol
, vol.194
, pp. 1252-1260
-
-
Oficjalska, K.1
Raverdeau, M.2
Aviello, G.3
-
188
-
-
85011281099
-
NLRP3 inflammasome mediates IL-1beta production in immune cells in response to Acinetobacter baumannii and contributes to pulmonary inflammation in mice
-
Kang MJ, Jo SG, Kim DJ, Park JH. NLRP3 inflammasome mediates IL-1beta production in immune cells in response to Acinetobacter baumannii and contributes to pulmonary inflammation in mice. Immunology. 2016;150:495-505.
-
(2016)
Immunology
, vol.150
, pp. 495-505
-
-
Kang, M.J.1
Jo, S.G.2
Kim, D.J.3
Park, J.H.4
-
189
-
-
84855272667
-
Inflammasome-dependent pyroptosis and IL-18 protect against Burkholderia pseudomallei lung infection while IL-1beta is deleterious
-
Ceballos-Olvera I, Sahoo M, Miller MA, Del Barrio L, Re F. Inflammasome-dependent pyroptosis and IL-18 protect against Burkholderia pseudomallei lung infection while IL-1beta is deleterious. PLoS Pathog. 2011;7:e1002452.
-
(2011)
PLoS Pathog
, vol.7
-
-
Ceballos-Olvera, I.1
Sahoo, M.2
Miller, M.A.3
Del Barrio, L.4
Re, F.5
-
190
-
-
63149157468
-
Caspase-1 mediates resistance in murine melioidosis
-
Breitbach K, Sun GW, Kohler J, et al. Caspase-1 mediates resistance in murine melioidosis. Infect Immun. 2009;77:1589-1595.
-
(2009)
Infect Immun
, vol.77
, pp. 1589-1595
-
-
Breitbach, K.1
Sun, G.W.2
Kohler, J.3
-
191
-
-
84860859210
-
Role of inflammasomes in host defense against Citrobacter rodentium infection
-
Liu Z, Zaki MH, Vogel P, et al. Role of inflammasomes in host defense against Citrobacter rodentium infection. J Biol Chem. 2012;287:16955-16964.
-
(2012)
J Biol Chem
, vol.287
, pp. 16955-16964
-
-
Liu, Z.1
Zaki, M.H.2
Vogel, P.3
-
192
-
-
84922333666
-
Type I interferon contributes to noncanonical inflammasome activation, mediates immunopathology, and impairs protective immunity during fatal infection with lipopolysaccharide-negative ehrlichiae
-
Yang Q, Stevenson HL, Scott MJ, Ismail N. Type I interferon contributes to noncanonical inflammasome activation, mediates immunopathology, and impairs protective immunity during fatal infection with lipopolysaccharide-negative ehrlichiae. Am J Pathol. 2015;185:446-461.
-
(2015)
Am J Pathol
, vol.185
, pp. 446-461
-
-
Yang, Q.1
Stevenson, H.L.2
Scott, M.J.3
Ismail, N.4
-
193
-
-
26844452231
-
Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis
-
Mariathasan S, Weiss DS, Dixit VM, Monack DM. Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis. J Exp Med. 2005;202:1043-1049.
-
(2005)
J Exp Med
, vol.202
, pp. 1043-1049
-
-
Mariathasan, S.1
Weiss, D.S.2
Dixit, V.M.3
Monack, D.M.4
-
194
-
-
85007579447
-
Inflammasome-independent NLRP3 restriction of a protective early neutrophil response to pulmonary tularemia
-
Periasamy S, Le HT, Duffy EB, Chin H, Harton JA. Inflammasome-independent NLRP3 restriction of a protective early neutrophil response to pulmonary tularemia. PLoS Pathog. 2016;12:e1006059.
-
(2016)
PLoS Pathog
, vol.12
-
-
Periasamy, S.1
Le, H.T.2
Duffy, E.B.3
Chin, H.4
Harton, J.A.5
-
195
-
-
83755183815
-
Activation of NLRC4 by flagellated bacteria triggers caspase-1-dependent and -independent responses to restrict Legionella pneumophila replication in macrophages and in vivo
-
Pereira MS, Morgantetti GF, Massis LM, Horta CV, Hori JI, Zamboni DS. Activation of NLRC4 by flagellated bacteria triggers caspase-1-dependent and -independent responses to restrict Legionella pneumophila replication in macrophages and in vivo. J Immunol. 2011;187:6447-6455.
-
(2011)
J Immunol
, vol.187
, pp. 6447-6455
-
-
Pereira, M.S.1
Morgantetti, G.F.2
Massis, L.M.3
Horta, C.V.4
Hori, J.I.5
Zamboni, D.S.6
-
196
-
-
84940118670
-
Caspase-1 but not caspase-11 is required for NLRC4-mediated pyroptosis and restriction of infection by flagellated Legionella species in mouse macrophages and in vivo
-
Cerqueira DM, Pereira MS, Silva AL, Cunha LD, Zamboni DS. Caspase-1 but not caspase-11 is required for NLRC4-mediated pyroptosis and restriction of infection by flagellated Legionella species in mouse macrophages and in vivo. J Immunol. 2015;195:2303-2311.
-
(2015)
J Immunol
, vol.195
, pp. 2303-2311
-
-
Cerqueira, D.M.1
Pereira, M.S.2
Silva, A.L.3
Cunha, L.D.4
Zamboni, D.S.5
-
197
-
-
77955390094
-
Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella
-
Broz P, Newton K, Lamkanfi M, Mariathasan S, Dixit VM, Monack DM. Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella. J Exp Med. 2010;207:1745-1755.
-
(2010)
J Exp Med
, vol.207
, pp. 1745-1755
-
-
Broz, P.1
Newton, K.2
Lamkanfi, M.3
Mariathasan, S.4
Dixit, V.M.5
Monack, D.M.6
-
198
-
-
0033679111
-
Caspase-1 activation of IL-1beta and IL-18 are essential for Shigella flexneri-induced inflammation
-
Sansonetti PJ, Phalipon A, Arondel J, et al. Caspase-1 activation of IL-1beta and IL-18 are essential for Shigella flexneri-induced inflammation. Immunity. 2000;12:581-590.
-
(2000)
Immunity
, vol.12
, pp. 581-590
-
-
Sansonetti, P.J.1
Phalipon, A.2
Arondel, J.3
-
199
-
-
77954521853
-
Pathogenic Vibrio activate NLRP3 inflammasome via cytotoxins and TLR/nucleotide-binding oligomerization domain-mediated NF-kappa B signaling
-
Toma C, Higa N, Koizumi Y, et al. Pathogenic Vibrio activate NLRP3 inflammasome via cytotoxins and TLR/nucleotide-binding oligomerization domain-mediated NF-kappa B signaling. J Immunol. 2010;184:5287-5297.
-
(2010)
J Immunol
, vol.184
, pp. 5287-5297
-
-
Toma, C.1
Higa, N.2
Koizumi, Y.3
-
200
-
-
84926489979
-
Yersinia pestis activates both IL-1beta and IL-1 receptor antagonist to modulate lung inflammation during pneumonic plague
-
Sivaraman V, Pechous RD, Stasulli NM, Eichelberger KR, Miao EA, Goldman WE. Yersinia pestis activates both IL-1beta and IL-1 receptor antagonist to modulate lung inflammation during pneumonic plague. PLoS Pathog. 2015;11:e1004688.
-
(2015)
PLoS Pathog
, vol.11
-
-
Sivaraman, V.1
Pechous, R.D.2
Stasulli, N.M.3
Eichelberger, K.R.4
Miao, E.A.5
Goldman, W.E.6
-
201
-
-
84871001488
-
The Yersinia virulence effector YopM binds caspase-1 to arrest inflammasome assembly and processing
-
LaRock CN, Cookson BT. The Yersinia virulence effector YopM binds caspase-1 to arrest inflammasome assembly and processing. Cell Host Microbe. 2012;12:799-805.
-
(2012)
Cell Host Microbe
, vol.12
, pp. 799-805
-
-
LaRock, C.N.1
Cookson, B.T.2
-
202
-
-
84860354862
-
YopJ-induced caspase-1 activation in Yersinia-infected macrophages: Independent of apoptosis, linked to necrosis, dispensable for innate host defense
-
Zheng Y, Lilo S, Mena P, Bliska JB. YopJ-induced caspase-1 activation in Yersinia-infected macrophages: Independent of apoptosis, linked to necrosis, dispensable for innate host defense. PLoS ONE. 2012;7:e36019.
-
(2012)
PLoS ONE
, vol.7
-
-
Zheng, Y.1
Lilo, S.2
Mena, P.3
Bliska, J.B.4
-
203
-
-
0034163325
-
Neutralization of IL-18 reduces neutrophil tissue accumulation and protects mice against lethal Escherichia coli and Salmonella Typhimurium endotoxemia
-
Netea MG, Fantuzzi G, Kullberg BJ, et al. Neutralization of IL-18 reduces neutrophil tissue accumulation and protects mice against lethal Escherichia coli and Salmonella Typhimurium endotoxemia. J Immunol. 2000;164:2644-2649.
-
(2000)
J Immunol
, vol.164
, pp. 2644-2649
-
-
Netea, M.G.1
Fantuzzi, G.2
Kullberg, B.J.3
-
204
-
-
84951933158
-
Caspase-11 and caspase-1 differentially modulate actin polymerization via RhoA and Slingshot proteins to promote bacterial clearance
-
Caution K, Gavrilin MA, Tazi M, et al. Caspase-11 and caspase-1 differentially modulate actin polymerization via RhoA and Slingshot proteins to promote bacterial clearance. Sci Rep. 2015;5:18479.
-
(2015)
Sci Rep
, vol.5
, pp. 18479
-
-
Caution, K.1
Gavrilin, M.A.2
Tazi, M.3
-
205
-
-
0036120378
-
Listeria monocytogenes infection in caspase-11-deficient mice
-
Mueller NJ, Wilkinson RA, Fishman JA. Listeria monocytogenes infection in caspase-11-deficient mice. Infect Immun. 2002;70:2657-2664.
-
(2002)
Infect Immun
, vol.70
, pp. 2657-2664
-
-
Mueller, N.J.1
Wilkinson, R.A.2
Fishman, J.A.3
-
206
-
-
0032548919
-
Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE
-
Wang S, Miura M, Jung YK, Zhu H, Li E, Yuan J. Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE. Cell. 1998;92:501-509.
-
(1998)
Cell
, vol.92
, pp. 501-509
-
-
Wang, S.1
Miura, M.2
Jung, Y.K.3
Zhu, H.4
Li, E.5
Yuan, J.6
-
207
-
-
78651258397
-
Inflammasome sensor Nlrp1b-dependent resistance to anthrax is mediated by caspase-1, IL-1 signaling and neutrophil recruitment
-
Moayeri M, Crown D, Newman ZL, et al. Inflammasome sensor Nlrp1b-dependent resistance to anthrax is mediated by caspase-1, IL-1 signaling and neutrophil recruitment. PLoS Pathog. 2010;6:e1001222.
-
(2010)
PLoS Pathog
, vol.6
-
-
Moayeri, M.1
Crown, D.2
Newman, Z.L.3
-
208
-
-
1042292574
-
Roles of caspase-1 in Listeria infection in mice
-
Tsuji NM, Tsutsui H, Seki E, et al. Roles of caspase-1 in Listeria infection in mice. Int Immunol. 2004;16:335-343.
-
(2004)
Int Immunol
, vol.16
, pp. 335-343
-
-
Tsuji, N.M.1
Tsutsui, H.2
Seki, E.3
-
209
-
-
84899474093
-
Critical role for the AIM2 inflammasome during acute CNS bacterial infection
-
Hanamsagar R, Aldrich A, Kielian T. Critical role for the AIM2 inflammasome during acute CNS bacterial infection. J Neurochem. 2014;129:704-711.
-
(2014)
J Neurochem
, vol.129
, pp. 704-711
-
-
Hanamsagar, R.1
Aldrich, A.2
Kielian, T.3
-
210
-
-
84856901248
-
Activation of the NLRP3 inflammasome by group B streptococci
-
Costa A, Gupta R, Signorino G, et al. Activation of the NLRP3 inflammasome by group B streptococci. J Immunol. 2012;188:1953-1960.
-
(2012)
J Immunol
, vol.188
, pp. 1953-1960
-
-
Costa, A.1
Gupta, R.2
Signorino, G.3
-
211
-
-
33846898975
-
Toll-like receptor 9 acts at an early stage in host defence against pneumococcal infection
-
Albiger B, Dahlberg S, Sandgren A, et al. Toll-like receptor 9 acts at an early stage in host defence against pneumococcal infection. Cell Microbiol. 2007;9:633-644.
-
(2007)
Cell Microbiol
, vol.9
, pp. 633-644
-
-
Albiger, B.1
Dahlberg, S.2
Sandgren, A.3
-
212
-
-
77957908944
-
Granuloma formation and host defense in chronic Mycobacterium tuberculosis infection requires PYCARD/ASC but not NLRP3 or caspase-1
-
McElvania Tekippe E, Allen IC, Hulseberg PD, et al. Granuloma formation and host defense in chronic Mycobacterium tuberculosis infection requires PYCARD/ASC but not NLRP3 or caspase-1. PLoS ONE. 2010;5:e12320.
-
(2010)
PLoS ONE
, vol.5
-
-
McElvania Tekippe, E.1
Allen, I.C.2
Hulseberg, P.D.3
-
213
-
-
77951628300
-
Caspase-1 independent IL-1beta production is critical for host resistance to Mycobacterium tuberculosis and does not require TLR signaling in vivo
-
Mayer-Barber KD, Barber DL, Shenderov K, et al. Caspase-1 independent IL-1beta production is critical for host resistance to Mycobacterium tuberculosis and does not require TLR signaling in vivo. J Immunol. 2010;184:3326-3330.
-
(2010)
J Immunol
, vol.184
, pp. 3326-3330
-
-
Mayer-Barber, K.D.1
Barber, D.L.2
Shenderov, K.3
-
214
-
-
79955370281
-
The NLRP3 inflammasome detects encephalomyocarditis virus and vesicular stomatitis virus infection
-
Rajan JV, Rodriguez D, Miao EA, Aderem A. The NLRP3 inflammasome detects encephalomyocarditis virus and vesicular stomatitis virus infection. J Virol. 2011;85:4167-4172.
-
(2011)
J Virol
, vol.85
, pp. 4167-4172
-
-
Rajan, J.V.1
Rodriguez, D.2
Miao, E.A.3
Aderem, A.4
-
215
-
-
84930892258
-
Murine gammaherpesvirus 68 pathogenesis is independent of caspase-1 and caspase-11 in mice and impairs interleukin-1beta production upon extrinsic stimulation in culture
-
Cieniewicz B, Dong Q, Li G, et al. Murine gammaherpesvirus 68 pathogenesis is independent of caspase-1 and caspase-11 in mice and impairs interleukin-1beta production upon extrinsic stimulation in culture. J Virol. 2015;89:6562-6574.
-
(2015)
J Virol
, vol.89
, pp. 6562-6574
-
-
Cieniewicz, B.1
Dong, Q.2
Li, G.3
-
216
-
-
84954472942
-
The Nlrp3 inflammasome, IL-1beta, and neutrophil recruitment are required for susceptibility to a nonhealing strain of Leishmania major in C57BL/6 mice
-
Charmoy M, Hurrell BP, Romano A, et al. The Nlrp3 inflammasome, IL-1beta, and neutrophil recruitment are required for susceptibility to a nonhealing strain of Leishmania major in C57BL/6 mice. Eur J Immunol. 2016;46:897-911.
-
(2016)
Eur J Immunol
, vol.46
, pp. 897-911
-
-
Charmoy, M.1
Hurrell, B.P.2
Romano, A.3
-
217
-
-
80052341059
-
Caspase-1 activation of interleukin-1beta (IL-1beta) and IL-18 is dispensable for induction of experimental cerebral malaria
-
Kordes M, Matuschewski K, Hafalla JC. Caspase-1 activation of interleukin-1beta (IL-1beta) and IL-18 is dispensable for induction of experimental cerebral malaria. Infect Immun. 2011;79:3633-3641.
-
(2011)
Infect Immun
, vol.79
, pp. 3633-3641
-
-
Kordes, M.1
Matuschewski, K.2
Hafalla, J.C.3
-
218
-
-
77749260601
-
Experimental cerebral malaria progresses independently of the Nlrp3 inflammasome
-
Reimer T, Shaw MH, Franchi L, et al. Experimental cerebral malaria progresses independently of the Nlrp3 inflammasome. Eur J Immunol. 2010;40:764-769.
-
(2010)
Eur J Immunol
, vol.40
, pp. 764-769
-
-
Reimer, T.1
Shaw, M.H.2
Franchi, L.3
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