YopJ-induced caspase-1 activation in yersinia-infected macrophages: Independent of apoptosis, linked to necrosis, dispensable for innate host defense

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Zheng, Ying ^a   Lilo, Sarit ^a   Mena, Patricio ^a   Bliska, James B ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CASPASE 3; CASPASE 7; CATHEPSIN B; CATHEPSIN B INHIBITOR; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NUCLEAR RECEPTOR COACTIVATOR 2; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; YERSINIA OUTER PROTEIN J; CASPASE 8; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; HIGH MOBILITY GROUP B1 PROTEIN; ISOPROTEIN; PROTEIN BAK; PROTEIN BAX; PROTEINASE INHIBITOR; RALBP1 PROTEIN, MOUSE; YOPP PROTEIN, YERSINIA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOKINE RESPONSE; CYTOTOXICITY; ENZYME ACTIVATION; FEMALE; GENE INACTIVATION; HOST PATHOGEN INTERACTION; HOST RESISTANCE; INNATE IMMUNITY; INTRACELLULAR SIGNALING; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN PROTEIN INTERACTION; YERSINIA INFECTION; YERSINIA PESTIS; YERSINIA PSEUDOTUBERCULOSIS; ANIMAL; C57BL MOUSE; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; MICROBIOLOGY; MITOCHONDRION; MOUSE MUTANT; NECROSIS; PATHOGENICITY; PATHOLOGY; PROTEIN BINDING; YERSINIA; YERSINIA ENTEROCOLITICA;

MURINAE; MUS; YERSINIA; YERSINIA ENTEROCOLITICA; YERSINIA PESTIS; YERSINIA PESTIS KIM; YERSINIA PSEUDOTUBERCULOSIS;

ANIMALS; APOPTOSIS; BACTERIAL PROTEINS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; CASPASE 1; CASPASE 3; CASPASE 7; CASPASE 8; CATHEPSIN B; CELLS, CULTURED; ENZYME ACTIVATION; FEMALE; GTPASE-ACTIVATING PROTEINS; HMGB1 PROTEIN; IMMUNITY, INNATE; INTERLEUKIN-1BETA; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; NECROSIS; PROTEASE INHIBITORS; PROTEIN BINDING; PROTEIN ISOFORMS; REACTIVE OXYGEN SPECIES; YERSINIA; YERSINIA ENTEROCOLITICA; YERSINIA INFECTIONS; YERSINIA PESTIS; YERSINIA PSEUDOTUBERCULOSIS;

EID: 84860354862     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0036019     Document Type: Article

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