Site-specific phosphorylation and microtubule dynamics control Pyrin inflammasome activation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 33, 2016, Pages E4857-E4866

  Gao, Wenqing ^a,b   Yang, Jieling ^b   Liu, Wang ^b   Wang, Yupeng ^b   Shao, Feng ^b  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES   (China)

Author keywords

FMF; Inflammasome; Phosphorylation; Pyrin; Rho toxins

Indexed keywords

COLCHICINE; INFLAMMASOME; INTERLEUKIN 1BETA CONVERTING ENZYME; PROTEIN 14 3 3; PYRIN INFLAMMASOME; SERINE; SERINE 205; SERINE 241; UNCLASSIFIED DRUG; BACTERIAL TOXIN; ENTEROTOXIN; PYRIN; TCDA PROTEIN, CLOSTRIDIUM DIFFICILE; TUBULIN MODULATOR;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BACTERIAL INFECTION; BACTERIAL VIRULENCE; BONE MARROW DERIVED DENDRITIC CELL; BONE MARROW DERIVED MACROPHAGE; CONTROLLED STUDY; FAMILIAL MEDITERRANEAN FEVER; HUMAN; INNATE IMMUNITY; MICROTUBULE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; SITE DIRECTED MUTAGENESIS; ANIMAL; C57BL MOUSE; HEK293 CELL LINE; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

14-3-3 PROTEINS; ANIMALS; BACTERIAL TOXINS; ENTEROTOXINS; HEK293 CELLS; HUMANS; INFLAMMASOMES; MICE; MICE, INBRED C57BL; MICROTUBULES; PHOSPHORYLATION; PYRIN; TUBULIN MODULATORS;

EID: 84982091531     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1601700113     Document Type: Article

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