Epithelium-intrinsic NAIP/NLRC4 inflammasome drives infected enterocyte expulsion to restrict salmonella replication in the intestinal mucosa

Cell Host and Microbe

Volumn 16, Issue 2, 2014, Pages 237-248

  Sellin, Mikael E ^a   Müller, Anna A ^a   Felmy, Boas ^a   Dolowschiak, Tamas ^a   Diard, Médéric ^a   Tardivel, Aubry ^b   Maslowski, Kendle M ^b,c   Hardt, Wolf Dietrich ^a  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c RIKEN Center for Integrative Medical Sciences   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 11; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; NAIP 1 PROTEIN; NAIP 2 PROTEIN; NAIP 3 PROTEIN; NAIP 4 PROTEIN; NAIP 5 PROTEIN; NAIP 6 PROTEIN; NEURONAL APOPTOSIS INHIBITORY PROTEIN; NLRC4 PROTEIN; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; CALCIUM BINDING PROTEIN; IPAF PROTEIN, MOUSE; NAIP1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL GROWTH; BACTERIAL LOAD; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENTEROCOLITIS; GENE DELETION; INFECTIOUS DIARRHEA; INTESTINE CELL; INTESTINE EPITHELIUM; INTESTINE FLORA; INTESTINE MUCOSA; LYMPH NODE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SALMONELLA ENTEROCOLITIS; SALMONELLA TYPHIMURIUM; SALMONELLOSIS; ANIMAL; C57BL MOUSE; CECUM; HOST PATHOGEN INTERACTION; IMMUNOLOGY; KNOCKOUT MOUSE; MICROBIOLOGY; PATHOLOGY; PHYSIOLOGY; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CALCIUM-BINDING PROTEINS; CECUM; ENTEROCYTES; HOST-PATHOGEN INTERACTIONS; INFLAMMASOMES; INTESTINAL MUCOSA; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONAL APOPTOSIS-INHIBITORY PROTEIN; SALMONELLA INFECTIONS; SALMONELLA TYPHIMURIUM;

EID: 84908024529     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2014.07.001     Document Type: Article

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