-
1
-
-
77954990444
-
Leishmaniasis vaccine where are we today?
-
Kedzierski L. Leishmaniasis vaccine: where are we today? J Glob Infect Dis. 2010;2(2):177-185.
-
(2010)
J Glob Infect Dis.
, vol.2
, Issue.2
, pp. 177-185
-
-
Kedzierski, L.1
-
2
-
-
84924046263
-
-
Center for Disease Control and Prevention. CDC Web site. Updated January 10, 2013. Accessed January 20
-
Center for Disease Control and Prevention. Parasites-Leishma niasis: Epidemiology and Risk Factors. CDC Web site. http://www.cdc.gov/parasites/leishmaniasis/epi.html. Updated January 10, 2013. Accessed January 20, 2014.
-
(2014)
Parasites-Leishma Niasis: Epidemiology and Risk Factors
-
-
-
3
-
-
56149121336
-
Complexities of assessing the disease burden attributable to leishmaniasis
-
Bern C, Maguire JH, Alvar J. Complexities of assessing the disease burden attributable to leishmaniasis. PLoS Negl Trop Dis. 2008;2(10):e313.
-
(2008)
PLoS Negl Trop Dis.
, vol.2
, Issue.10
, pp. e313
-
-
Bern, C.1
Maguire, J.H.2
Alvar, J.3
-
4
-
-
79951919391
-
Cell biology and immunology of leishmania
-
Mougneau E, Bihl F, Gl aichenhaus N. Cell biology and immunology of Leishmania. Immunol Rev. 2011;240(1):286-296.
-
(2011)
Immunol Rev.
, vol.240
, Issue.1
, pp. 286-296
-
-
Mougneau, E.1
Bihl, F.2
Glaichenhaus, N.3
-
5
-
-
0024236111
-
Immunoregulation of cutaneous leishmania sis. T cell lines that transfer protective immunity or exacerbation belong to different t helper subsets and respond to distinct parasite antigens
-
Scott P, Natovitz P, Coffman RL, Pearce E, Sher A. Immunoregulation of cutaneous leishmania sis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens. J Exp Med. 1988;168(5):1675-1684.
-
(1988)
J Exp Med.
, vol.168
, Issue.5
, pp. 1675-1684
-
-
Scott, P.1
Natovitz, P.2
Coffman, R.L.3
Pearce, E.4
Sher, A.5
-
6
-
-
0024540908
-
Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper t cell subsets
-
Heinzel FP, Sadick MD, Holaday BJ, Coffman RL, Locksley RM. Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets. J Exp Med. 1989;169(1):59-72.
-
(1989)
J Exp Med.
, vol.169
, Issue.1
, pp. 59-72
-
-
Heinzel, F.P.1
Sadick, M.D.2
Holaday, B.J.3
Coffman, R.L.4
Locksley, R.M.5
-
7
-
-
0025768733
-
Production of interferon gamma, interleukin 2, interleukin 4, and interleukin 10 by cd4+ lymphocytes in vivo during healing and p rogressive murine leishmaniasis
-
Heinzel FP, Sadick MD, Mutha SS, Locksley RM. Production of interferon gamma, interleukin 2, interleukin 4, and interleukin 10 by CD4+ lymphocytes in vivo during healing and p rogressive murine leishmaniasis. Proc Natl Acad Sci U S A. 1991;88(16):7011-7015.
-
(1991)
Proc Natl Acad Sci U S A.
, vol.88
, Issue.16
, pp. 7011-7015
-
-
Heinzel, F.P.1
Sadick, M.D.2
Mutha, S.S.3
Locksley, R.M.4
-
9
-
-
79953046719
-
The inflammasome nlrs in immunity, inflammation, and associated diseases
-
Davis BK, Wen H, Ting JP. The inflammasome NLRs in immunity, inflammation, and associated diseases. Annu Rev Immunol. 2011;29:707-735.
-
(2011)
Annu Rev Immunol.
, vol.29
, pp. 707-735
-
-
Davis, B.K.1
Wen, H.2
Ting, J.P.3
-
10
-
-
0037108346
-
Cutting edge: Caterpiller: A large family of mammalian genes containing card, pyrin, nucleotide-binding, and leucine-rich repeat domains
-
Harton JA, Linh off MW, Zhang J, Ting JP. Cutting edge: CATERPILLER: a large family of mammalian genes containing CARD, pyrin, nucleotide-binding, and leucine-rich repeat domains. J Immunol. 2002;169(8):4088-4093.
-
(2002)
J Immunol.
, vol.169
, Issue.8
, pp. 4088-4093
-
-
Harton, J.A.1
Linhoff, M.W.2
Zhang, J.3
Ting, J.P.4
-
11
-
-
0035474227
-
The nod: A signaling module that regulates apoptosis and host defense against pathogens
-
Inohara N, Nunez G. The NOD: a signaling module that regulates apoptosis and host defense against pathogens. Oncogene. 2001;20(44):6473-6481.
-
(2001)
Oncogene.
, vol.20
, Issue.44
, pp. 6473-6481
-
-
Inohara, N.1
Nunez, G.2
-
12
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proil-?
-
Martinon F,Burns K,Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-? Mol Cell. 2002 10 2 417-426.
-
(2002)
Mol Cell.
, vol.10
, Issue.2
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
13
-
-
1642285783
-
Nalp3 forms an il-1?-processing inflammasome with increased activity in muckle-wells autoinflammatory disorder
-
Agostini L, Martinon F, Burns K, McDermott MF, Hawkins PN, Tschopp J. NALP3 forms an IL-1?-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity. 2004;20(3):319-325.
-
(2004)
Immunity.
, vol.20
, Issue.3
, pp. 319-325
-
-
Agostini, L.1
Martinon, F.2
Burns, K.3
McDermott, M.F.4
Hawkins, P.N.5
Tschopp, J.6
-
14
-
-
32944462834
-
Bacterial rna and small antiviral compounds activate caspase-1 through cryopyrin/nalp3
-
Kanneganti TD, et al. Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature. 2006;440(7081):233-236.
-
(2006)
Nature.
, vol.440
, Issue.7081
, pp. 233-236
-
-
Kanneganti, T.D.1
-
15
-
-
77957228318
-
Central roles of nlrs and inflammasomes in viral infection
-
Kanneganti TD. Central roles of NLRs and inflammasomes in viral infection. Nat Rev Immunol. 2010;10(10):688-698.
-
(2010)
Nat Rev Immunol.
, vol.10
, Issue.10
, pp. 688-698
-
-
Kanneganti, T.D.1
-
16
-
-
84894271641
-
Fadd and caspase-8 mediate priming and activation of the canonical and noncanonical nlrp3 inflammasomes
-
Gurung P, et al. FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes. J Immunol. 2014;192(4):1835-1846.
-
(2014)
J Immunol.
, vol.192
, Issue.4
, pp. 1835-1846
-
-
Gurung, P.1
-
17
-
-
84867241369
-
Toll or interleukin-1 receptor (tir) domain-containing adaptor inducing interferon-? (trif)-mediated caspase-11 protease production integrates toll-like receptor 4 (tlr4) protein-And nlrp3 inflammasome-mediated host defense against enteropathogens
-
Gurung P, et al. Toll or interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-? (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4) protein-And Nlrp3 inflammasome-mediated host defense against enteropathogens. J Biol Chem. 2012;287(41):34474-34483.
-
(2012)
J Biol Chem.
, vol.287
, Issue.41
, pp. 34474-34483
-
-
Gurung, P.1
-
18
-
-
64049096334
-
The intracellular sensor nlrp3 mediates key innate and healing responses to influenza a virus via the regulation of caspase-1
-
Thomas PG, et al. The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1. Immunity. 2009;30(4):566-575.
-
(2009)
Immunity.
, vol.30
, Issue.4
, pp. 566-575
-
-
Thomas, P.G.1
-
19
-
-
2542457495
-
Inflammatory caspases: Linking an intracellular innate immune system to autoinflammatory diseases
-
Martinon F, Tschopp J. Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases. Cell. 2004;117(5):561-574.
-
(2004)
Cell.
, vol.117
, Issue.5
, pp. 561-574
-
-
Martinon, F.1
Tschopp, J.2
-
21
-
-
0024352297
-
Macrophage activation by interferon-? from host-protective t cells is inhibited by interleukin (il)3 and il4 produced by disease-promoting t cells in leishmaniasis
-
Liew FY, Millott S, Li Y, Lelchuk R, Chan WL, Ziltener H. Macrophage activation by interferon-? from host-protective T cells is inhibited by interleukin (IL)3 and IL4 produced by disease-promoting T cells in leishmaniasis. Eur J Immun ol. 1989;19(7):1227-1232.
-
(1989)
Eur J Immun Ol.
, vol.19
, Issue.7
, pp. 1227-1232
-
-
Liew, F.Y.1
Millott, S.2
Li, Y.3
Lelchuk, R.4
Chan, W.L.5
Ziltener, H.6
-
22
-
-
0024460107
-
Il-4 inhibits h2o2 production and antileishmanial capacity of human cultured monocytes mediated by ifn-?
-
Lehn M, Weiser WY, Engelhorn S, Gillis S, Remold HG. IL-4 inhibits H2O2 production and antileishmanial capacity of human cultured monocytes mediated by IFN-?. J Immunol. 1989;143(9):3020-3024.
-
(1989)
J Immunol.
, vol.143
, Issue.9
, pp. 3020-3024
-
-
Lehn, M.1
Weiser, W.Y.2
Engelhorn, S.3
Gillis, S.4
Remold, H.G.5
-
23
-
-
0032433126
-
Genetic regulation of commitment to interleukin 4 production by a cd4(+) t cell-intrinsic mechanism
-
Bix M, Wang ZE, Thiel B, Schork NJ, Locksley RM. Genetic regulation of commitment to interleukin 4 production by a CD4(+) T cell-intrinsic mechanism. J Exp Med. 1998;188(12):2289-2299.
-
(1998)
J Exp Med.
, vol.188
, Issue.12
, pp. 2289-2299
-
-
Bix, M.1
Wang, Z.E.2
Thiel, B.3
Schork, N.J.4
Locksley, R.M.5
-
24
-
-
64849086164
-
Il-17 promotes progression of cutaneous leishmaniasis in susceptible mic e
-
Lopez Kostka S, Dinges S, Griewank K, Iwakura Y, Udey MC, von Stebut E. IL-17 promotes progression of cutaneous leishmaniasis in susceptible mic e. J Immunol. 2009;182(5):3039-3046.
-
(2009)
J Immunol.
, vol.182
, Issue.5
, pp. 3039-3046
-
-
Lopez Kostka, S.1
Dinges, S.2
Griewank, K.3
Iwakura, Y.4
Udey, M.C.5
Von Stebut, E.6
-
25
-
-
64049089798
-
Critical regulation of early th17 cell differentiation by interleukin-1 signaling
-
Chung Y, et al. Critical regulation of early Th17 cell differentiation by interleukin-1 signaling. Immunity. 2009;30(4):576-587.
-
(2009)
Immunity.
, vol.30
, Issue.4
, pp. 576-587
-
-
Chung, Y.1
-
26
-
-
0024589297
-
Functional heterogeneity of cd4 + t cells in leishmaniasis
-
Liew FY. Functional heterogeneity of CD4 + T cells in leishmaniasis. Immunol Today. 1989;10(2):40-45.
-
(1989)
Immunol Today.
, vol.10
, Issue.2
, pp. 40-45
-
-
Liew, F.Y.1
-
27
-
-
0025661887
-
Tumour necrosis factor (tnf-?) in leishmaniasis. Ii. Tnf-?-induced macrophage leishmanicidal activity i s mediated by nitric oxide from l-Arginine
-
Liew FY, Li Y, Millott S. Tumour necrosis factor (TNF-?) in leishmaniasis. II. TNF-?-induced macrophage leishmanicidal activity i s mediated by nitric oxide from L-Arginine. Immunology. 1990;71(4):556-559.
-
(1990)
Immunology.
, vol.71
, Issue.4
, pp. 556-559
-
-
Liew, F.Y.1
Li, Y.2
Millott, S.3
-
28
-
-
0025300228
-
Macrophage killing of leishmania parasite in vivo is med iated by nitric oxide from l-Arginine
-
Liew FY, Millott S, Parkinson C, Palmer RM, Moncada S. Macrophage killing of Leishmania parasite in vivo is med iated by nitric oxide from L-Arginine. J Immunol. 1990;144(12):4794-4797.
-
(1990)
J Immunol.
, vol.144
, Issue.12
, pp. 4794-4797
-
-
Liew, F.Y.1
Millott, S.2
Parkinson, C.3
Palmer, R.M.4
Moncada, S.5
-
29
-
-
0025309606
-
Tumour necrosis factor (tnf?) in leishmaniasis. i . Tnf? Mediates host protection against cutaneous leishmaniasis
-
Liew FY, Parkinson C, Millott S, Severn A, Carrier M. Tumour necrosis factor (TNF?) in leishmaniasis. I . TNF? mediates host protection against cutaneous leishmaniasis. Immunology. 1990;69(4):570-573.
-
(1990)
Immunology.
, vol.69
, Issue.4
, pp. 570-573
-
-
Liew, F.Y.1
Parkinson, C.2
Millott, S.3
Severn, A.4
Carrier, M.5
-
30
-
-
0030810155
-
The transcription factor gata-3 is necessary and sufficient for th2 cytokine gene expression in cd4 t cells
-
Zheng W, Flavell RA. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell. 1997;89(4):587-596.
-
(1997)
Cell.
, vol.89
, Issue.4
, pp. 587-596
-
-
Zheng, W.1
Flavell, R.A.2
-
31
-
-
0030604714
-
The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4
-
Ho IC, Hodge MR, Rooney JW, Glimcher LH. The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4. Cell. 1996;85(7):973-983.
-
(1996)
Cell.
, vol.85
, Issue.7
, pp. 973-983
-
-
Ho, I.C.1
Hodge, M.R.2
Rooney, J.W.3
Glimcher, L.H.4
-
32
-
-
0032212793
-
Inhibition of th1 development mediated by gata-3 through an il-4-independent mechanism
-
Ouyang W, et al. Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism. Immunity. 1998;9(5):745-755.
-
(1998)
Immunity.
, vol.9
, Issue.5
, pp. 745-755
-
-
Ouyang, W.1
-
33
-
-
0035809309
-
An instructive component in t helper cell type 2 (th2) development mediated by gata-3
-
Farrar JD,et al An instructive component in T helper cell type 2 (Th2) development mediated by GATA-3 J Exp Med. 2001 193 5, 643-650.
-
(2001)
J Exp Med.
, vol.193
, Issue.5
, pp. 643-650
-
-
Farrar, J.D.1
-
34
-
-
79960392640
-
Leishmaniasis: Complexity at the host-pathogen interface
-
Kaye P, Scott P. Leishmaniasis: complexity at the host-pathogen interface. Nat Rev Microbiol. 2011;9(8):604-615.
-
(2011)
Nat Rev Microbiol.
, vol.9
, Issue.8
, pp. 604-615
-
-
Kaye, P.1
Scott, P.2
-
35
-
-
80052397027
-
A current perspective on leishmaniasis
-
Clem A. A current perspective on leishmaniasis. J Glob Infect Dis. 2010;2(2):124-126.
-
(2010)
J Glob Infect Dis.
, vol.2
, Issue.2
, pp. 124-126
-
-
Clem, A.1
-
36
-
-
0020056077
-
Experimental cutaneous leishmaniasis: Disseminated leishmaniasis in genetically susceptible and resistant mice
-
Scott PA, Farrell JP. Experimental cutaneous leishmaniasis: disseminated leishmaniasis in genetically susceptible and resistant mice. Am J Trop Med Hyg. 1982;31(2):230-238.
-
(1982)
Am J Trop Med Hyg.
, vol.31
, Issue.2
, pp. 230-238
-
-
Scott, P.A.1
Farrell, J.P.2
-
37
-
-
84880255426
-
Inflammasome-derived il-1? Production induces nitric oxide-mediated resistance to leishmania
-
Lima-Junior DS, et al. Inflammasome-derived IL-1? production induces nitric oxide-mediated resistance to Leishmania. Nat Med. 2013;19(7):909-915.
-
(2013)
Nat Med.
, vol.19
, Issue.7
, pp. 909-915
-
-
Lima-Junior, D.S.1
-
38
-
-
0021368067
-
Inbred mice as model hosts for cutaneous leishmaniasis. I. Resistance and susceptibility to infection with leishmania braziliensis, l. Mexicana, and l. Aethiopica
-
Childs GE, Lightner LK, McKinney L, Groves MG, Price EE, Hendricks LD. Inbred mice as model hosts for cutaneous leishmaniasis. I. Resistance and susceptibility to infection with Leishmania braziliensis, L. mexicana, and L. aethiopica. Ann Trop Med Parasitol. 1984;78(1):25-34.
-
(1984)
Ann Trop Med Parasitol.
, vol.78
, Issue.1
, pp. 25-34
-
-
Childs, G.E.1
Lightner, L.K.2
McKinney, L.3
Groves, M.G.4
Price, E.E.5
Hendricks, L.D.6
-
39
-
-
0036831673
-
The immunology of susceptibility and resistance to leishmania major in mice
-
Sacks D, Noben-Trauth N. The immunology of susceptibility and resistance to Leishmania major in mice. Nat Rev Immunol. 2002;2(11):845-858.
-
(2002)
Nat Rev Immunol.
, vol.2
, Issue.11
, pp. 845-858
-
-
Sacks, D.1
Noben-Trauth, N.2
-
40
-
-
0020585973
-
Susceptibility of inbred mice to leishmania tropica i nfection: Correlation of susceptibility with in vitro defective macrophage microbicidal activities
-
Nacy CA, Fortier AH, Pappas MG, Henry RR. Susceptibility of inbred mice to Leishmania tropica i nfection: correlation of susceptibility with in vitro defective macrophage microbicidal activities. Cell Immunol. 1983;77(2):298-307.
-
(1983)
Cell Immunol.
, vol.77
, Issue.2
, pp. 298-307
-
-
Nacy, C.A.1
Fortier, A.H.2
Pappas, M.G.3
Henry, R.R.4
-
41
-
-
2942720427
-
Il-18 gene therapy develops th1-type immune res ponses in leishmania major-infected balb/c mice: Is the effect mediated by the cpg signaling tlr9?
-
Li Y, et al. IL-18 gene therapy develops Th1-type immune res ponses in Leishmania major-infected BALB/c mice: is the effect mediated by the CpG signaling TLR9? Gene Ther. 2004;11(11):941-948.
-
(2004)
Gene Ther.
, vol.11
, Issue.11
, pp. 941-948
-
-
Li, Y.1
-
42
-
-
45849094044
-
Interleukin-18 enhances a th2 bi ased response and susceptibility to leishmania mexicana in balb/c mice
-
Bryson KJ, Wei XQ, Alexander J. Interleukin-18 enhances a Th2 bi ased response and susceptibility to Leishmania mexicana in BALB/c mice. Microbes Infect. 2008;10(7):834-839.
-
(2008)
Microbes Infect.
, vol.10
, Issue.7
, pp. 834-839
-
-
Bryson, K.J.1
Wei, X.Q.2
Alexander, J.3
-
43
-
-
3242665088
-
Host genetic background determines whether il-18 deficiency results in increased susceptibility or resistance to murine leishmania major infection
-
Wei XQ, Niedbala W, Xu D, Luo ZX, Pollock KG, Brewer JM. Host genetic background determines whether IL-18 deficiency results in increased susceptibility or resistance to murine Leishmania major infection. Immunol Lett. 2004;94(1):35-37.
-
(2004)
Immunol Lett.
, vol.94
, Issue.1
, pp. 35-37
-
-
Wei, X.Q.1
Niedbala, W.2
Xu, D.3
Luo, Z.X.4
Pollock, K.G.5
Brewer, J.M.6
-
44
-
-
0033730039
-
Il-18 induces the differentiation of th1 or th2 cells depending upon cytokine milieu and genetic background
-
Xu D, et al. IL-18 induces the differentiation of Th1 or Th2 cells depending upon cytokine milieu and genetic background. Eur J Immunol. 2000;30(11):3147-3156.
-
(2000)
Eur J Immunol.
, vol.30
, Issue.11
, pp. 3147-3156
-
-
Xu, D.1
-
45
-
-
8944226108
-
Interferon-?-inducing factor enhances t helper 1 cytokine production by stimulated human t cells: Synergism with interleukin-12 for interferon-? Production
-
Micallef MJ, et al. Interferon-?-inducing factor enhances T helper 1 cytokine production by stimulated human T cells: synergism with interleukin-12 for interferon-? production. Eur J Immunol. 1996;26(7):1647-1651.
-
(1996)
Eur J Immunol.
, vol.26
, Issue.7
, pp. 1647-1651
-
-
Micallef, M.J.1
-
46
-
-
0031568526
-
Ifn-?-inducing factor (igif) is a costimulatory factor on the activation of th1 but not th2 cells and exerts its effect independently of il-12
-
Kohno K, et al. IFN-?-inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12. J Immunol. 1997;158(4):1541-1550.
-
(1997)
J Immunol.
, vol.158
, Issue.4
, pp. 1541-1550
-
-
Kohno, K.1
-
47
-
-
0028845730
-
Cloning of a new cytokine that induces ifn-? Production by t cells
-
Okamura H, et al. Cloning of a new cytokine that induces IFN-? production by T cells. Nature. 1995;378(6552):88-91.
-
(1995)
Nature.
, vol.378
, Issue.6552
, pp. 88-91
-
-
Okamura, H.1
-
48
-
-
3142654767
-
Differe ntial activation of the inflammasome by caspase-1 adaptors asc and ipaf
-
Mariathasan S, et al. Differe ntial activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature. 2004;430(6996):213-218.
-
(2004)
Nature.
, vol.430
, Issue.6996
, pp. 213-218
-
-
Mariathasan, S.1
-
49
-
-
80455176839
-
Non-canonical inflammasome activation targets caspase-11
-
Kayagaki N, et al. Non-canonical inflammasome activation targets caspase-11. Nature. 2011;479(7371):117-121.
-
(2011)
Nature.
, vol.479
, Issue.7371
, pp. 117-121
-
-
Kayagaki, N.1
-
50
-
-
11844288876
-
A leishmania major response locus identified by interval-specific congenic mapping of a t helper type 2 cell bias-controlling quantitati ve trait locus
-
Baguet A, Epler J, Wen KW, Bix M. A Leishmania major response locus identified by interval-specific congenic mapping of a T helper type 2 cell bias-controlling quantitati ve trait locus. J Exp Med. 2004;200(12):1605-1612.
-
(2004)
J Exp Med.
, vol.200
, Issue.12
, pp. 1605-1612
-
-
Baguet, A.1
Epler, J.2
Wen, K.W.3
Bix, M.4
|