Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions

Journal of Cell Biology

Volumn 149, Issue 3, 2000, Pages 613-622

  Kang, Shin Jung ^a   Wang, Suyue ^a   Hara, Hideaki ^b   Peterson, Erin P ^c   Namura, Shobu ^b   Amin Hanjani, Sepideh ^b   Huang, Zhihong ^b   Srinivasan, Anu ^d   Tomaselli, Kevin J ^d   Thornberry, Nancy A ^c   Moskowitz, Michael A ^b   Yuan, Junying ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

^d PFIZER INC   (United States)

Author keywords

Apoptosis; Caspase 11; Initiator caspase; Middle cerebral artery occlusion; Stroke

Indexed keywords

CASPASE 11; CASPASE 3; INTERLEUKIN 1BETA CONVERTING ENZYME; TUBULIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME PURIFICATION; ENZYME REGULATION; IMMUNOREGULATION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; BRAIN ISCHEMIA; CASPASE 1; CASPASE 3; CASPASES; CELL LINE; CEREBROVASCULAR ACCIDENT; COMBINATORIAL CHEMISTRY TECHNIQUES; CYTOKINES; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; IMMUNOHISTOCHEMISTRY; KINETICS; MICE; MICE, KNOCKOUT; PROTEIN PRECURSORS; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

EID: 0034192466     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.149.3.613     Document Type: Article

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