Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases

Nature

Volumn 509, Issue 7500, 2014, Pages 366-370

  Meunier, Etienne ^a   Dick, Mathias S ^a   Dreier, Roland F ^a   Schürmann, Nura ^a   Broz, Daniela Kenzelmann ^b   Warming, Søren ^c   Roose Girma, Merone ^c   Bumann, Dirk ^a   Kayagaki, Nobuhiko ^c   Takeda, Kiyoshi ^d   Yamamoto, Masahiro ^d   Broz, Petr ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b UNIVERSITY OF BASEL   (Switzerland)

^c GENENTECH INC   (United States)

^d OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 11; GALECTIN 8; GUANINE NUCLEOTIDE BINDING PROTEIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LACTATE DEHYDROGENASE; REACTIVE OXYGEN METABOLITE;

BACTERIUM; CYTOPLASM; ENZYME ACTIVITY; LYSIS; PATHOGEN; POLYSACCHARIDE; PROTEIN;

ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BURKHOLDERIA THAILANDENSIS; CELL ACTIVATION; CELL DEATH; CELL VACUOLE; CITROBACTER KOSERI; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOLYSIS; ENTEROBACTER CLOACAE; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; IMMUNOHISTOCHEMISTRY; LISTERIA MONOCYTOGENES; MOUSE; MYCOBACTERIUM BOVIS; NONHUMAN; PHAGOSOME; PRIORITY JOURNAL; SALMONELLA TYPHIMURIUM; SHIGELLA FLEXNERI; VIBRIO CHOLERAE;

ANIMALS; AUTOPHAGY; CASPASES; CYTOSOL; ENZYME ACTIVATION; GALECTINS; GRAM-NEGATIVE BACTERIA; GTP PHOSPHOHYDROLASES; IMMUNITY, INNATE; INFLAMMASOMES; INTERFERON TYPE I; LIPOPOLYSACCHARIDES; MICE; PHAGOSOMES; SALMONELLA TYPHIMURIUM; VACUOLES;

EID: 84900564237     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13157     Document Type: Article

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