Erratum: Pore-forming activity and structural autoinhibition of the gasdermin family (Nature (2016) 535 (111-116) DOI: 10.1038/nature18590);Pore-forming activity and structural autoinhibition of the gasdermin family

Nature

Volumn 535, Issue 7610, 2016, Pages 111-116

  Ding, Jingjin ^a,b   Wang, Kun ^b   Liu, Wang ^b   She, Yang ^a,b   Sun, Qi ^b   Shi, Jianjin ^b   Sun, Hanzi ^b   Wang, Da Cheng ^a,c   Shao, Feng ^a,b  

^a INSTITUTE OF BIOPHYSICS   (China)

^b NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES   (China)

^c FOSHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOLIPIN; GASDERMIN; LIPOSOME; MEMBRANE LIPID; PHOSPHATIDYLINOSITIDE; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG; CASPASE; DNA BINDING PROTEIN; GSDMA PROTEIN, HUMAN; GSDMA3 PROTEIN, MOUSE; GSDMB PROTEIN, HUMAN; GSDMC PROTEIN, HUMAN; GSDMD PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL; PROTEIN; TUMOR MARKER; TUMOR PROTEIN;

APOPTOSIS; BACTERIUM; CELLS AND CELL COMPONENTS; DISEASE INCIDENCE; IMMUNITY; MEMBRANE; PHOSPHOLIPID; PROTEIN;

ARTICLE; CYTOTOXICITY; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN STRUCTURE; PYROPTOSIS; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; HUMAN; IMMUNOLOGY; METABOLISM; MOUSE; NECROSIS; POROSITY; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

MAMMALIA;

ANIMALS; BIOMARKERS, TUMOR; CARDIOLIPINS; CASPASES; CELL LINE; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CRYSTALLOGRAPHY, X-RAY; DNA-BINDING PROTEINS; HUMANS; LIPOSOMES; MEMBRANE LIPIDS; MICE; MODELS, MOLECULAR; NECROSIS; NEOPLASM PROTEINS; PHOSPHATIDYLINOSITOLS; POROSITY; PROTEIN STRUCTURE, TERTIARY; PROTEINS; PYROPTOSIS;

EID: 84978419608     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature20106     Document Type: Erratum

References (42)

1. Jorgensen, I. and Miao, E. A. Pyroptotic cell death defends against intracellular pathogens. Immunol. Rev. 265, 130-142 (2015).
2. Cookson, B. T. and Brennan, M. A. Pro-inflammatory programmed cell death. Trends Microbiol. 9, 113-114 (2001).
3. Shi, J. et al. Inflammatory caspases are innate immune receptors for intracellular LPS. Nature 514, 187-192 (2014).
4. Kayagaki, N. et al. Non-canonical inflammasome activation targets caspase-11. Nature 479, 117-121 (2011).
5. Lamkanfi, M. and Dixit, V. M. Mechanisms and functions of inflammasomes. Cell 157, 1013-1022 (2014).
6. Zhao, Y. and Shao, F. Diverse mechanisms for inflammasome sensing of cytosolic bacteria and bacterial virulence. Curr. Opin. Microbiol. 29, 37-42 (2016).
7. Hagar, J. A., Powell, D. A., Aachoui, Y., Ernst, R. K. and Miao, E. A. Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock. Science 341, 1250-1253 (2013).
8. Kayagaki, N. et al. Noncanonical inflammasome activation by intracellular LPS independent of TLR4. Science 341, 1246-1249 (2013).
9. Yang, J., Zhao, Y. and Shao, F. Non-canonical activation of inflammatory caspases by cytosolic LPS in innate immunity. Curr. Opin. Immunol. 32, 78-83 (2015).
10. Shi, J. et al. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death. Nature 526, 660-665 (2015).
11. Kayagaki, N. et al. Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling. Nature 526, 666-671 (2015).
12. Saeki, N. and Sasaki, H. in Endothelium and Epithelium: Composition, Functions, and Pathology (eds Carrasco, J. and Matheus, M.) Ch. IX, 193-211 (Nova Science Publishers, 2011).
13. Tanaka, S., Mizushina, Y., Kato, Y., Tamura, M. and Shiroishi, T. Functional conservation of Gsdma cluster genes specifically duplicated in the mouse genome. G3 (Bethesda) 3, 1843-1850 (2013).
14. Sato, H. et al. A new mutation Rim3 resembling Reden is mapped close to retinoic acid receptor alpha (Rara) gene on mouse chromosome 11. Mamm. Genome 9, 20-25 (1998).
15. Porter, R. M. et al. Defolliculated (dfl): a dominant mouse mutation leading to poor sebaceous gland differentiation and total elimination of pelage follicles. J. Invest. Dermatol. 119, 32-37 (2002).
16. Runkel, F. et al. The dominant alopecia phenotypes Bareskin, Rex-denuded, and Reduced Coat 2 are caused by mutations in gasdermin 3. Genomics 84, 824-835 (2004).
17. Van Laer, L. et al. Nonsyndromic hearing impairment is associated with a mutation in DFNA5. Nat. Genet. 20, 194-197 (1998).
18. Delmaghani, S. et al. Mutations in the gene encoding pejvakin, a newly identified protein of the afferent auditory pathway, cause DFNB59 auditory neuropathy. Nat. Genet. 38, 770-778 (2006).
19. Shepard, L. A., Shatursky, O., Johnson, A. E. and Tweten, R. K. The mechanism of pore assembly for a cholesterol-dependent cytolysin: formation of a large prepore complex precedes the insertion of the transmembrane beta-hairpins. Biochemistry 39, 10284-10293 (2000).
20. Fink, S. L., Bergsbaken, T. and Cookson, B. T. Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms. Proc. Natl Acad. Sci. USA 105, 4312-4317 (2008).
21. Holm, L. and Rosenstrom, P. Dali server: conservation mapping in 3D. Nucleic Acids Res. 38, W545-W549 (2010).
22. Delmaghani, S. et al. Hypervulnerability to sound exposure through impaired adaptive proliferation of peroxisomes. Cell 163, 894-906 (2015).
23. Van Rossom, S., Op de Beeck, K., Hristovska, V., Winderickx, J. and Van Camp, G. The deafness gene DFNA5 induces programmed cell death through mitochondria and MAPK-related pathways. Front. Cell. Neurosci. 9, 231 (2015).
24. Bischofberger, M., Iacovache, I. and van der Goot, F. G. Pathogenic poreforming proteins: function and host response. Cell Host Microbe 12, 266-275 (2012).
25. Hildebrand, J. M. et al. Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death. Proc. Natl Acad. Sci. USA 111, 15072-15077 (2014).
26. Dondelinger, Y. et al. MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates. Cell Reports 7, 971-981 (2014).
27. Wang, H. et al. Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3. Mol. Cell 54, 133-146 (2014).
28. Cai, Z. et al. Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis. Nat. Cell Biol. 16, 55-65 (2014).
29. Iacovache, I., Bischofberger, M. and van der Goot, F. G. Structure and assembly of pore-forming proteins. Curr. Opin. Struct. Biol. 20, 241-246 (2010).
30. Reboul, C. F., Whisstock, J. C. and Dunstone, M. A. Giant MACPF/CDC pore forming toxins: A class of their own. Biochim. Biophys. Acta 1858, 475-486 (2016).
31. Zhao, Y. et al. The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Nature 477, 596-600 (2011).
32. Gong, Y.-N. et al. Chemical probing reveals insights into the signaling mechanism of inflammasome activation. Cell Res. 20, 1289-1305 (2010).
33. Wilschut, J. and Papahadjopoulos, D. Ca2+-induced fusion of phospholipid vesicles monitored by mixing of aqueous contents. Nature 281, 690-692 (1979).
34. Tang, G. et al. EMAN2: an extensible image processing suite for electron microscopy. J. Struct. Biol. 157, 38-46 (2007).
35. Scheres, S. H. A Bayesian view on cryo-EM structure determination. J. Mol. Biol. 415, 406-418 (2012).
36. Frank, J. et al. SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields. J. Struct. Biol. 116, 190-199 (1996).
37. Otwinowski, Z. and Minor, W. in Methods in Enzymology Vol. 276 (eds Carter, C. W. Jr and Sweet, R. M.) 307-326 (Academic, 1997).
38. Adams, P. D. et al. PHENIX: a comprehensive Python-based system for macromolecular structure solution. Acta Crystallogr. D 66, 213-221 (2010).
39. Emsley, P., Lohkamp, B., Scott, W. G. and Cowtan, K. Features and development of Coot. Acta Crystallogr. D 66, 486-501 (2010).
40. Chen, V. B. et al. MolProbity: all-atom structure validation for macromolecular crystallography. Acta Crystallogr. D 66, 12-21 (2010).
41. Eswar, N. et al. Comparative protein structure modeling using MODELLER. Curr. Protoc. Protein Sci. Chapter 2, Unit 2.9 (2007).
42. Shen, M. Y. and Sali, A. Statistical potential for assessment and prediction of protein structures. Protein Sci. 15, 2507-2524 (2006).