Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 20, 2014, Pages 7403-7408

  Man, Si Ming ^a   Hopkins, Lee J ^a   Nugent, Eileen ^b   Cox, Susan ^c   Glück, Ivo M ^a   Tourlomousis, Panagiotis ^a   Wright, John A ^a   Cicuta, Pietro ^b   Monie, Tom P ^a   Bryant, Clare E ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; NUCLEOTIDE BINDING DOMAIN AND LEUCINE RICH REPEAT CASPASE RECRUITMENT DOMAIN 4; NUCLEOTIDE BINDING DOMAIN AND LEUCINE RICH REPEAT PYRIN DOMAIN 3; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BACTERIAL LOAD; CONTROLLED STUDY; ENZYME ACTIVATION; INFLAMMATION; MACROMOLECULE; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN STRUCTURE; SALMONELLA TYPHIMURIUM; SALMONELLOSIS; SPATIAL ORIENTATION;

ASC; BACTERIA; CASPASE-1; CASPASE-8; INNATE IMMUNITY;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BONE MARROW CELLS; CALCIUM-BINDING PROTEINS; CARRIER PROTEINS; CASPASE 1; CASPASE 8; ENZYME ACTIVATION; HEK293 CELLS; HUMANS; INFLAMMASOMES; INFLAMMATION; INTERLEUKIN-1BETA; MACROPHAGES; MICE; MICE, TRANSGENIC; SALMONELLA TYPHIMURIUM;

EID: 84901008921     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1402911111     Document Type: Article

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