Critical role for the AIM2 inflammasome during acute CNS bacterial infection

Journal of Neurochemistry

Volumn 129, Issue 4, 2014, Pages 704-711

  Hanamsagar, Richa ^a,b   Aldrich, Amy ^a   Kielian, Tammy ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b DUKE UNIVERSITY   (United States)

Author keywords

AIM2; ASC; caspase 1; inflammasome; interleukin 1; Staphylococcus aureus

Indexed keywords

CASPASE 11; CRYOPYRIN; CXCL1 CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; MEMBRANE PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN AIM2; PROTEIN ASC; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; BACTERIUM DETECTION; CENTRAL NERVOUS SYSTEM INFECTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN SECRETION; STAPHYLOCOCCUS INFECTION; SURVIVAL;

ANIMALIA; BACTERIA (MICROORGANISMS); MUS; STAPHYLOCOCCUS AUREUS;

AIM2; ASC; CASPASE 1; INFLAMMASOME; INTERLEUKIN-1; STAPHYLOCOCCUS AUREUS;

ANIMALS; BRAIN ABSCESS; CARRIER PROTEINS; CASPASE 1; CASPASES; CYTOKINES; CYTOSKELETAL PROTEINS; DISEASE SUSCEPTIBILITY; DNA, BACTERIAL; FEMALE; IMMUNITY, INNATE; INFLAMMASOMES; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; MALE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; MODELS, IMMUNOLOGICAL; NUCLEAR PROTEINS; PHENOTYPE; STAPHYLOCOCCAL INFECTIONS;

EID: 84899474093     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12669     Document Type: Article

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