-
1
-
-
77954187759
-
Chagas disease: a new worldwide challenge
-
Coura JR, Vinas PA, (2010) Chagas disease: a new worldwide challenge. Nature 465: S6-7.
-
(2010)
Nature
, vol.465
-
-
Coura, J.R.1
Vinas, P.A.2
-
2
-
-
77953023715
-
Chagas disease in Spain, the United States and other non-endemic countries
-
Gascon J, Bern C, Pinazo MJ, (2010) Chagas disease in Spain, the United States and other non-endemic countries. Acta Trop 115: 22-27.
-
(2010)
Acta Trop
, vol.115
, pp. 22-27
-
-
Gascon, J.1
Bern, C.2
Pinazo, M.J.3
-
4
-
-
84858254437
-
The Immune Response to Trypanosoma cruzi: Role of Toll-Like Receptors and Perspectives for Vaccine Development
-
Rodrigues MM, Oliveira AC, Bellio M, (2012) The Immune Response to Trypanosoma cruzi: Role of Toll-Like Receptors and Perspectives for Vaccine Development. J Parasitol Res 2012: 507874.
-
(2012)
J Parasitol Res
, vol.2012
, pp. 507874
-
-
Rodrigues, M.M.1
Oliveira, A.C.2
Bellio, M.3
-
5
-
-
33845204804
-
Protozoan encounters with Toll-like receptor signalling pathways: implications for host parasitism
-
Gazzinelli RT, Denkers EY, (2006) Protozoan encounters with Toll-like receptor signalling pathways: implications for host parasitism. Nat RevImmunol 6: 895-906.
-
(2006)
Nat RevImmunol
, vol.6
, pp. 895-906
-
-
Gazzinelli, R.T.1
Denkers, E.Y.2
-
6
-
-
6344241296
-
Expression of functional TLR4 confers proinflammatory responsiveness to Trypanosoma cruzi glycoinositolphospholipids and higher resistance to infection with T. cruzi
-
Oliveira AC, Peixoto JR, de Arruda LB, Campos MA, Gazzinelli RT, et al. (2004) Expression of functional TLR4 confers proinflammatory responsiveness to Trypanosoma cruzi glycoinositolphospholipids and higher resistance to infection with T. cruzi. J Immunol 173: 5688-5696.
-
(2004)
J Immunol
, vol.173
, pp. 5688-5696
-
-
Oliveira, A.C.1
Peixoto, J.R.2
de Arruda, L.B.3
Campos, M.A.4
Gazzinelli, R.T.5
-
7
-
-
0036066134
-
Macrophage signaling by glycosylphosphatidylinositol-anchored mucin-like glycoproteins derived from Trypanosoma cruzi trypomastigotes
-
Ropert C, Ferreira LR, Campos MA, Procopio DO, Travassos LR, et al. (2002) Macrophage signaling by glycosylphosphatidylinositol-anchored mucin-like glycoproteins derived from Trypanosoma cruzi trypomastigotes. Microbes Infect 4: 1015-1025.
-
(2002)
Microbes Infect
, vol.4
, pp. 1015-1025
-
-
Ropert, C.1
Ferreira, L.R.2
Campos, M.A.3
Procopio, D.O.4
Travassos, L.R.5
-
8
-
-
0034599521
-
Highly purified glycosylphosphatidylinositols from Trypanosoma cruzi are potent proinflammatory agents
-
Almeida IC, Camargo MM, Procopio DO, Silva LS, Mehlert A, et al. (2000) Highly purified glycosylphosphatidylinositols from Trypanosoma cruzi are potent proinflammatory agents. EMBO J 19: 1476-1485.
-
(2000)
EMBO J
, vol.19
, pp. 1476-1485
-
-
Almeida, I.C.1
Camargo, M.M.2
Procopio, D.O.3
Silva, L.S.4
Mehlert, A.5
-
9
-
-
0035399862
-
Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite
-
Campos MA, Almeida IC, Takeuchi O, Akira S, Valente EP, et al. (2001) Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite. J Immunol 167: 416-423.
-
(2001)
J Immunol
, vol.167
, pp. 416-423
-
-
Campos, M.A.1
Almeida, I.C.2
Takeuchi, O.3
Akira, S.4
Valente, E.P.5
-
10
-
-
33748477504
-
Cutting edge: TLR9 and TLR2 signaling together account for MyD88-dependent control of parasitemia in Trypanosoma cruzi infection
-
Bafica A, Santiago HC, Goldszmid R, Ropert C, Gazzinelli RT, et al. (2006) Cutting edge: TLR9 and TLR2 signaling together account for MyD88-dependent control of parasitemia in Trypanosoma cruzi infection. J Immunol 177: 3515-3519.
-
(2006)
J Immunol
, vol.177
, pp. 3515-3519
-
-
Bafica, A.1
Santiago, H.C.2
Goldszmid, R.3
Ropert, C.4
Gazzinelli, R.T.5
-
11
-
-
80051937446
-
Requirement of UNC93B1 reveals a critical role for TLR7 in host resistance to primary infection with Trypanosoma cruzi
-
Caetano BC, Carmo BB, Melo MB, Cerny A, dos Santos SL, et al. (2011) Requirement of UNC93B1 reveals a critical role for TLR7 in host resistance to primary infection with Trypanosoma cruzi. J Immunol 187: 1903-1911.
-
(2011)
J Immunol
, vol.187
, pp. 1903-1911
-
-
Caetano, B.C.1
Carmo, B.B.2
Melo, M.B.3
Cerny, A.4
dos Santos, S.L.5
-
12
-
-
0030010929
-
Interleukin-12 mediates resistance to Trypanosoma cruzi in mice and is produced by murine macrophages in response to live trypomastigotes
-
Aliberti JC, Cardoso MA, Martins GA, Gazzinelli RT, Vieira LQ, et al. (1996) Interleukin-12 mediates resistance to Trypanosoma cruzi in mice and is produced by murine macrophages in response to live trypomastigotes. Infect Immun 64: 1961-1967.
-
(1996)
Infect Immun
, vol.64
, pp. 1961-1967
-
-
Aliberti, J.C.1
Cardoso, M.A.2
Martins, G.A.3
Gazzinelli, R.T.4
Vieira, L.Q.5
-
13
-
-
0035149345
-
Pivotal role of interleukin-12 and interferon-gamma axis in controlling tissue parasitism and inflammation in the heart and central nervous system during Trypanosoma cruzi infection
-
Michailowsky V, Silva NM, Rocha CD, Vieira LQ, Lannes-Vieira J, et al. (2001) Pivotal role of interleukin-12 and interferon-gamma axis in controlling tissue parasitism and inflammation in the heart and central nervous system during Trypanosoma cruzi infection. Am J Pathol 159: 1723-1733.
-
(2001)
Am J Pathol
, vol.159
, pp. 1723-1733
-
-
Michailowsky, V.1
Silva, N.M.2
Rocha, C.D.3
Vieira, L.Q.4
Lannes-Vieira, J.5
-
14
-
-
0041562493
-
Interleukin-12 but not interleukin-18 is required for immunity to Trypanosoma cruzi in mice
-
Graefe SE, Jacobs T, Gaworski I, Klauenberg U, Steeg C, et al. (2003) Interleukin-12 but not interleukin-18 is required for immunity to Trypanosoma cruzi in mice. Microbes Infect 5: 833-839.
-
(2003)
Microbes Infect
, vol.5
, pp. 833-839
-
-
Graefe, S.E.1
Jacobs, T.2
Gaworski, I.3
Klauenberg, U.4
Steeg, C.5
-
15
-
-
0036486831
-
Macrophages from IL-12p40-deficient mice have a bias toward the M2 activation profile
-
Bastos KR, Alvarez JM, Marinho CR, Rizzo LV, Lima MR, (2002) Macrophages from IL-12p40-deficient mice have a bias toward the M2 activation profile. J LeukocBiol 71: 271-278.
-
(2002)
J LeukocBiol
, vol.71
, pp. 271-278
-
-
Bastos, K.R.1
Alvarez, J.M.2
Marinho, C.R.3
Rizzo, L.V.4
Lima, M.R.5
-
16
-
-
0030025945
-
Regulation of Trypanosoma cruzi infection in mice by gamma interferon and interleukin 10: role of NK cells
-
Cardillo F, Voltarelli JC, Reed SG, Silva JS, (1996) Regulation of Trypanosoma cruzi infection in mice by gamma interferon and interleukin 10: role of NK cells. Infect Immun 64: 128-134.
-
(1996)
Infect Immun
, vol.64
, pp. 128-134
-
-
Cardillo, F.1
Voltarelli, J.C.2
Reed, S.G.3
Silva, J.S.4
-
17
-
-
0028051548
-
Nitric oxide is involved in control of Trypanosoma cruzi-induced parasitemia and directly kills the parasite in vitro
-
Vespa GN, Cunha FQ, Silva JS, (1994) Nitric oxide is involved in control of Trypanosoma cruzi-induced parasitemia and directly kills the parasite in vitro. Infect Immun 62: 5177-5182.
-
(1994)
Infect Immun
, vol.62
, pp. 5177-5182
-
-
Vespa, G.N.1
Cunha, F.Q.2
Silva, J.S.3
-
18
-
-
0031913243
-
Defective nitric oxide effector functions lead to extreme susceptibility of Trypanosoma cruzi-infected mice deficient in gamma interferon receptor or inducible nitric oxide synthase
-
Holscher C, Kohler G, Muller U, Mossmann H, Schaub GA, et al. (1998) Defective nitric oxide effector functions lead to extreme susceptibility of Trypanosoma cruzi-infected mice deficient in gamma interferon receptor or inducible nitric oxide synthase. Infect Immun 66: 1208-1215.
-
(1998)
Infect Immun
, vol.66
, pp. 1208-1215
-
-
Holscher, C.1
Kohler, G.2
Muller, U.3
Mossmann, H.4
Schaub, G.A.5
-
19
-
-
1642525756
-
Impaired production of proinflammatory cytokines and host resistance to acute infection with Trypanosoma cruzi in mice lacking functional myeloid differentiation factor 88
-
Campos MA, Closel M, Valente EP, Cardoso JE, Akira S, et al. (2004) Impaired production of proinflammatory cytokines and host resistance to acute infection with Trypanosoma cruzi in mice lacking functional myeloid differentiation factor 88. J Immunol 172: 1711-1718.
-
(2004)
J Immunol
, vol.172
, pp. 1711-1718
-
-
Campos, M.A.1
Closel, M.2
Valente, E.P.3
Cardoso, J.E.4
Akira, S.5
-
20
-
-
77949326831
-
Cutting edge: nucleotide-binding oligomerization domain 1-dependent responses account for murine resistance against Trypanosoma cruzi infection
-
Silva GK, Gutierrez FR, Guedes PM, Horta CV, Cunha LD, et al. (2010) Cutting edge: nucleotide-binding oligomerization domain 1-dependent responses account for murine resistance against Trypanosoma cruzi infection. J Immunol 184: 1148-1152.
-
(2010)
J Immunol
, vol.184
, pp. 1148-1152
-
-
Silva, G.K.1
Gutierrez, F.R.2
Guedes, P.M.3
Horta, C.V.4
Cunha, L.D.5
-
21
-
-
77951911814
-
Control of infection by pyroptosis and autophagy: role of TLR and NLR
-
Bortoluci KR, Medzhitov R, (2010) Control of infection by pyroptosis and autophagy: role of TLR and NLR. Cell Mol Life Sci 67 (10) (): 1643-51.
-
(2010)
Cell Mol Life Sci
, vol.67
, Issue.10
, pp. 1643-1651
-
-
Bortoluci, K.R.1
Medzhitov, R.2
-
22
-
-
77950362382
-
The inflammasomes
-
Schroder K, Tschopp J, (2010) The inflammasomes. Cell 140: 821-832.
-
(2010)
Cell
, vol.140
, pp. 821-832
-
-
Schroder, K.1
Tschopp, J.2
-
23
-
-
84858677223
-
Sensing and reacting to microbes through the inflammasomes
-
Franchi L, Munoz-Planillo R, Nunez G, (2012) Sensing and reacting to microbes through the inflammasomes. Nat Immunol 13: 325-332.
-
(2012)
Nat Immunol
, vol.13
, pp. 325-332
-
-
Franchi, L.1
Munoz-Planillo, R.2
Nunez, G.3
-
24
-
-
33744464740
-
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages
-
Franchi L, Amer A, Body-Malapel M, Kanneganti TD, Ozoren N, et al. (2006) Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages. Nat Immunol 7: 576-582.
-
(2006)
Nat Immunol
, vol.7
, pp. 576-582
-
-
Franchi, L.1
Amer, A.2
Body-Malapel, M.3
Kanneganti, T.D.4
Ozoren, N.5
-
25
-
-
77649241461
-
Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome
-
Miao EA, Mao DP, Yudkovsky N, Bonneau R, Lorang CG, et al. (2010) Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome. Proc Natl Acad Sci U S A 107: 3076-3080.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 3076-3080
-
-
Miao, E.A.1
Mao, D.P.2
Yudkovsky, N.3
Bonneau, R.4
Lorang, C.G.5
-
26
-
-
77951263260
-
The AIM2 inflammasome is critical for innate immunity to Francisella tularensis
-
Fernandes-Alnemri T, Yu JW, Juliana C, Solorzano L, Kang S, et al. (2010) The AIM2 inflammasome is critical for innate immunity to Francisella tularensis. Nat Immunol 11: 385-393.
-
(2010)
Nat Immunol
, vol.11
, pp. 385-393
-
-
Fernandes-Alnemri, T.1
Yu, J.W.2
Juliana, C.3
Solorzano, L.4
Kang, S.5
-
27
-
-
77951269392
-
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
-
Rathinam VA, Jiang Z, Waggoner SN, Sharma S, Cole LE, et al. (2010) The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses. Nat Immunol 11: 395-402.
-
(2010)
Nat Immunol
, vol.11
, pp. 395-402
-
-
Rathinam, V.A.1
Jiang, Z.2
Waggoner, S.N.3
Sharma, S.4
Cole, L.E.5
-
28
-
-
33846014297
-
Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA
-
Kanneganti TD, Body-Malapel M, Amer A, Park JH, Whitfield J, et al. (2006) Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA. J BiolChem 281: 36560-36568.
-
(2006)
J BiolChem
, vol.281
, pp. 36560-36568
-
-
Kanneganti, T.D.1
Body-Malapel, M.2
Amer, A.3
Park, J.H.4
Whitfield, J.5
-
29
-
-
77749270973
-
Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2X7 receptor
-
Harder J, Franchi L, Munoz-Planillo R, Park JH, Reimer T, et al. (2009) Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2X7 receptor. J Immunol 183: 5823-5829.
-
(2009)
J Immunol
, vol.183
, pp. 5823-5829
-
-
Harder, J.1
Franchi, L.2
Munoz-Planillo, R.3
Park, J.H.4
Reimer, T.5
-
30
-
-
76249108958
-
Listeria monocytogenes-infected human peripheral blood mononuclear cells produce IL-1beta, depending on listeriolysin O and NLRP3
-
Meixenberger K, Pache F, Eitel J, Schmeck B, Hippenstiel S, et al. (2010) Listeria monocytogenes-infected human peripheral blood mononuclear cells produce IL-1beta, depending on listeriolysin O and NLRP3. J Immunol 184: 922-930.
-
(2010)
J Immunol
, vol.184
, pp. 922-930
-
-
Meixenberger, K.1
Pache, F.2
Eitel, J.3
Schmeck, B.4
Hippenstiel, S.5
-
31
-
-
77955482224
-
Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome
-
552 e541-542543
-
Ng J, Hirota SA, Gross O, Li Y, Ulke-Lemee A, et al. (2010) Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome. Gastroenterology 139: 542-552, 552 e541-543.
-
(2010)
Gastroenterology
, vol.139
, pp. 542-552
-
-
Ng, J.1
Hirota, S.A.2
Gross, O.3
Li, Y.4
Ulke-Lemee, A.5
-
32
-
-
65549154784
-
An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans
-
Hise AG, Tomalka J, Ganesan S, Patel K, Hall BA, et al. (2009) An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans. Cell Host Microbe 5: 487-497.
-
(2009)
Cell Host Microbe
, vol.5
, pp. 487-497
-
-
Hise, A.G.1
Tomalka, J.2
Ganesan, S.3
Patel, K.4
Hall, B.A.5
-
33
-
-
68349157477
-
Malarial hemozoin is a Nalp3 inflammasome activating danger signal
-
Dostert C, Guarda G, Romero JF, Menu P, Gross O, et al. (2009) Malarial hemozoin is a Nalp3 inflammasome activating danger signal. PLoS One 4: e6510.
-
(2009)
PLoS One
, vol.4
-
-
Dostert, C.1
Guarda, G.2
Romero, J.F.3
Menu, P.4
Gross, O.5
-
34
-
-
70449727077
-
Glyburide inhibits the Cryopyrin/Nalp3 inflammasome
-
Lamkanfi M, Mueller JL, Vitari AC, Misaghi S, Fedorova A, et al. (2009) Glyburide inhibits the Cryopyrin/Nalp3 inflammasome. J Cell Biol 187: 61-70.
-
(2009)
J Cell Biol
, vol.187
, pp. 61-70
-
-
Lamkanfi, M.1
Mueller, J.L.2
Vitari, A.C.3
Misaghi, S.4
Fedorova, A.5
-
35
-
-
77749245832
-
The controversial relationship between NLRP3, alum, danger signals and the next-generation adjuvants
-
Spreafico R, Ricciardi-Castagnoli P, Mortellaro A, (2010) The controversial relationship between NLRP3, alum, danger signals and the next-generation adjuvants. Eur J Immunol 40: 638-642.
-
(2010)
Eur J Immunol
, vol.40
, pp. 638-642
-
-
Spreafico, R.1
Ricciardi-Castagnoli, P.2
Mortellaro, A.3
-
36
-
-
47849087075
-
Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3
-
Li H, Willingham SB, Ting JP, Re F, (2008) Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3. J Immunol 181: 17-21.
-
(2008)
J Immunol
, vol.181
, pp. 17-21
-
-
Li, H.1
Willingham, S.B.2
Ting, J.P.3
Re, F.4
-
37
-
-
45749111446
-
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
-
Eisenbarth SC, Colegio OR, O'Connor W, Sutterwala FS, Flavell RA, (2008) Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. Nature 453: 1122-1126.
-
(2008)
Nature
, vol.453
, pp. 1122-1126
-
-
Eisenbarth, S.C.1
Colegio, O.R.2
O'Connor, W.3
Sutterwala, F.S.4
Flavell, R.A.5
-
38
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, et al. (2008) Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol 9: 847-856.
-
(2008)
Nat Immunol
, vol.9
, pp. 847-856
-
-
Hornung, V.1
Bauernfeind, F.2
Halle, A.3
Samstad, E.O.4
Kono, H.5
-
39
-
-
77249118801
-
The inflammasomes: mechanisms of activation and function
-
Latz E, (2010) The inflammasomes: mechanisms of activation and function. Curr Opin Immunol 22: 28-33.
-
(2010)
Curr Opin Immunol
, vol.22
, pp. 28-33
-
-
Latz, E.1
-
40
-
-
77749304034
-
Critical functions of priming and lysosomal damage for NLRP3 activation
-
Hornung V, Latz E, (2010) Critical functions of priming and lysosomal damage for NLRP3 activation. Eur J Immunol 40: 620-623.
-
(2010)
Eur J Immunol
, vol.40
, pp. 620-623
-
-
Hornung, V.1
Latz, E.2
-
41
-
-
77957554717
-
Molecular mechanism of NLRP3 inflammasome activation
-
Jin C, Flavell RA, (2010) Molecular mechanism of NLRP3 inflammasome activation. J Clin Immunol 30: 628-631.
-
(2010)
J Clin Immunol
, vol.30
, pp. 628-631
-
-
Jin, C.1
Flavell, R.A.2
-
42
-
-
84860491760
-
Activation of an NLRP3 inflammasome restricts Mycobacterium kansasii infection
-
Chen CC, Tsai SH, Lu CC, Hu ST, Wu TS, et al. (2012) Activation of an NLRP3 inflammasome restricts Mycobacterium kansasii infection. PLoS One 7: e36292.
-
(2012)
PLoS One
, vol.7
-
-
Chen, C.C.1
Tsai, S.H.2
Lu, C.C.3
Hu, S.T.4
Wu, T.S.5
-
43
-
-
84860859210
-
Role of inflammasomes in host defense against Citrobacter rodentium infection
-
Liu Z, Zaki MH, Vogel P, Gurung P, Finlay BB, et al. (2012) Role of inflammasomes in host defense against Citrobacter rodentium infection. J Biol Chem 287: 16955-16964.
-
(2012)
J Biol Chem
, vol.287
, pp. 16955-16964
-
-
Liu, Z.1
Zaki, M.H.2
Vogel, P.3
Gurung, P.4
Finlay, B.B.5
-
44
-
-
77955390094
-
Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella
-
Broz P, Newton K, Lamkanfi M, Mariathasan S, Dixit VM, et al. (2010) Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella. J ExpMed 207: 1745-1755.
-
(2010)
J ExpMed
, vol.207
, pp. 1745-1755
-
-
Broz, P.1
Newton, K.2
Lamkanfi, M.3
Mariathasan, S.4
Dixit, V.M.5
-
45
-
-
84875431649
-
Critical Role of ASC Inflammasomes and Bacterial Type IV Secretion System in Caspase-1 Activation and Host Innate Resistance to Brucella abortus Infection
-
Gomes MT, Campos PC, Oliveira FS, Corsetti PP, Bortoluci KR, et al. (2013) Critical Role of ASC Inflammasomes and Bacterial Type IV Secretion System in Caspase-1 Activation and Host Innate Resistance to Brucella abortus Infection. J Immunol 190: 3629-3638.
-
(2013)
J Immunol
, vol.190
, pp. 3629-3638
-
-
Gomes, M.T.1
Campos, P.C.2
Oliveira, F.S.3
Corsetti, P.P.4
Bortoluci, K.R.5
-
46
-
-
60549112774
-
Inflammasome recognition of influenza virus is essential for adaptive immune responses
-
Ichinohe T, Lee HK, Ogura Y, Flavell R, Iwasaki A, (2009) Inflammasome recognition of influenza virus is essential for adaptive immune responses. J Exp Med 206: 79-87.
-
(2009)
J Exp Med
, vol.206
, pp. 79-87
-
-
Ichinohe, T.1
Lee, H.K.2
Ogura, Y.3
Flavell, R.4
Iwasaki, A.5
-
47
-
-
64049096334
-
The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1
-
Thomas PG, Dash P, Aldridge JR Jr, Ellebedy AH, Reynolds C, et al. (2009) The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1. Immunity 30: 566-575.
-
(2009)
Immunity
, vol.30
, pp. 566-575
-
-
Thomas, P.G.1
Dash, P.2
Aldridge Jr., J.R.3
Ellebedy, A.H.4
Reynolds, C.5
-
48
-
-
64049111768
-
The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA
-
Allen IC, Scull MA, Moore CB, Holl EK, McElvania-TeKippe E, et al. (2009) The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity 30: 556-565.
-
(2009)
Immunity
, vol.30
, pp. 556-565
-
-
Allen, I.C.1
Scull, M.A.2
Moore, C.B.3
Holl, E.K.4
McElvania-TeKippe, E.5
-
49
-
-
84879133824
-
Evaluation of pyroptosis in macrophages using cytosolic delivery of purified flagellin
-
Lage SL, Amarante-Mendes GP, Bortoluci KR, (2013) Evaluation of pyroptosis in macrophages using cytosolic delivery of purified flagellin. Methods 61: 110-116.
-
(2013)
Methods
, vol.61
, pp. 110-116
-
-
Lage, S.L.1
Amarante-Mendes, G.P.2
Bortoluci, K.R.3
-
50
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariathasan S, Weiss DS, Newton K, McBride J, O'Rourke K, et al. (2006) Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440: 228-232.
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
-
51
-
-
77956263518
-
Role of host lysosomal associated membrane protein (LAMP) in Trypanosoma cruzi invasion and intracellular development
-
Albertti LA, Macedo AM, Chiari E, Andrews NW, Andrade LO, (2010) Role of host lysosomal associated membrane protein (LAMP) in Trypanosoma cruzi invasion and intracellular development. Microbes Infect 12: 784-789.
-
(2010)
Microbes Infect
, vol.12
, pp. 784-789
-
-
Albertti, L.A.1
Macedo, A.M.2
Chiari, E.3
Andrews, N.W.4
Andrade, L.O.5
-
52
-
-
67349271142
-
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
-
Gross O, Poeck H, Bscheider M, Dostert C, Hannesschlager N, et al. (2009) Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence. Nature 459: 433-436.
-
(2009)
Nature
, vol.459
, pp. 433-436
-
-
Gross, O.1
Poeck, H.2
Bscheider, M.3
Dostert, C.4
Hannesschlager, N.5
-
53
-
-
70049101754
-
Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases
-
Shio MT, Eisenbarth SC, Savaria M, Vinet AF, Bellemare MJ, et al. (2009) Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases. PLoSPathog 5: e1000559.
-
(2009)
PLoSPathog
, vol.5
-
-
Shio, M.T.1
Eisenbarth, S.C.2
Savaria, M.3
Vinet, A.F.4
Bellemare, M.J.5
-
54
-
-
84880255426
-
Inflammasome-derived IL-1beta production induces nitric oxide-mediated resistance to Leishmania
-
Lima-Junior DS, Costa DL, Carregaro V, Cunha LD, Silva AL, et al. (2013) Inflammasome-derived IL-1beta production induces nitric oxide-mediated resistance to Leishmania. Nat Med 19: 909-915.
-
(2013)
Nat Med
, vol.19
, pp. 909-915
-
-
Lima-Junior, D.S.1
Costa, D.L.2
Carregaro, V.3
Cunha, L.D.4
Silva, A.L.5
-
55
-
-
79952108690
-
The endless race between Trypanosoma cruzi and host immunity: lessons for and beyond Chagas disease
-
Junqueira C, Caetano B, Bartholomeu DC, Melo MB, Ropert C, et al. (2010) The endless race between Trypanosoma cruzi and host immunity: lessons for and beyond Chagas disease. Expert Rev Mol Med 12: e29.
-
(2010)
Expert Rev Mol Med
, vol.12
-
-
Junqueira, C.1
Caetano, B.2
Bartholomeu, D.C.3
Melo, M.B.4
Ropert, C.5
-
56
-
-
68949219809
-
The effects of nitric oxide on the immune system during Trypanosoma cruzi infection
-
Gutierrez FR, Mineo TW, Pavanelli WR, Guedes PM, Silva JS, (2009) The effects of nitric oxide on the immune system during Trypanosoma cruzi infection. Mem Inst Oswaldo Cruz 104 Suppl 1: 236-245.
-
(2009)
Mem Inst Oswaldo Cruz
, vol.104
, Issue.SUPPL.
, pp. 236-245
-
-
Gutierrez, F.R.1
Mineo, T.W.2
Pavanelli, W.R.3
Guedes, P.M.4
Silva, J.S.5
-
57
-
-
0029119310
-
Role of nitric oxide in resistance and histopathology during experimental infection with Trypanosoma cruzi
-
Petray P, Castanos-Velez E, Grinstein S, Orn A, Rottenberg ME, (1995) Role of nitric oxide in resistance and histopathology during experimental infection with Trypanosoma cruzi. Immuno lLett 47: 121-126.
-
(1995)
Immuno LLett
, vol.47
, pp. 121-126
-
-
Petray, P.1
Castanos-Velez, E.2
Grinstein, S.3
Orn, A.4
Rottenberg, M.E.5
-
58
-
-
0035081911
-
Stage-dependent role of nitric oxide in control of Trypanosoma cruzi infection
-
Saeftel M, Fleischer B, Hoerauf A, (2001) Stage-dependent role of nitric oxide in control of Trypanosoma cruzi infection. Infect Immun 69: 2252-2259.
-
(2001)
Infect Immun
, vol.69
, pp. 2252-2259
-
-
Saeftel, M.1
Fleischer, B.2
Hoerauf, A.3
-
59
-
-
78449269290
-
Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria
-
Miao EA, Leaf IA, Treuting PM, Mao DP, Dors M, et al. (2010) Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria. Nat Immunol 11: 1136-1142.
-
(2010)
Nat Immunol
, vol.11
, pp. 1136-1142
-
-
Miao, E.A.1
Leaf, I.A.2
Treuting, P.M.3
Mao, D.P.4
Dors, M.5
-
60
-
-
77957766952
-
A novel pathway for inducible nitric-oxide synthase activation through inflammasomes
-
Buzzo CL, Campopiano JC, Massis LM, Lage SL, Cassado AA, et al. (2010) A novel pathway for inducible nitric-oxide synthase activation through inflammasomes. J BiolChem 285: 32087-32095.
-
(2010)
J BiolChem
, vol.285
, pp. 32087-32095
-
-
Buzzo, C.L.1
Campopiano, J.C.2
Massis, L.M.3
Lage, S.L.4
Cassado, A.A.5
-
61
-
-
84860325913
-
Inflammasome-activated caspase 7 cleaves PARP1 to enhance the expression of a subset of NF-kappaB target genes
-
Erener S, Petrilli V, Kassner I, Minotti R, Castillo R, et al. (2012) Inflammasome-activated caspase 7 cleaves PARP1 to enhance the expression of a subset of NF-kappaB target genes. Mol Cell 46: 200-211.
-
(2012)
Mol Cell
, vol.46
, pp. 200-211
-
-
Erener, S.1
Petrilli, V.2
Kassner, I.3
Minotti, R.4
Castillo, R.5
-
62
-
-
33749260519
-
Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going?
-
Hassa PO, Haenni SS, Elser M, Hottiger MO, (2006) Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going? Microbiol Mol Biol Rev 70: 789-829.
-
(2006)
Microbiol Mol Biol Rev
, vol.70
, pp. 789-829
-
-
Hassa, P.O.1
Haenni, S.S.2
Elser, M.3
Hottiger, M.O.4
-
63
-
-
0032863224
-
A role of poly (ADP-ribose) polymerase in NF-kappaB transcriptional activation
-
Hassa PO, Hottiger MO, (1999) A role of poly (ADP-ribose) polymerase in NF-kappaB transcriptional activation. Biol Chem 380: 953-959.
-
(1999)
Biol Chem
, vol.380
, pp. 953-959
-
-
Hassa, P.O.1
Hottiger, M.O.2
-
64
-
-
9644295773
-
Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammation response in mice
-
Petrilli V, Herceg Z, Hassa PO, Patel NS, Di Paola R, et al. (2004) Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammation response in mice. J Clin Invest 114: 1072-1081.
-
(2004)
J Clin Invest
, vol.114
, pp. 1072-1081
-
-
Petrilli, V.1
Herceg, Z.2
Hassa, P.O.3
Patel, N.S.4
Di Paola, R.5
-
65
-
-
84866654832
-
Inhibition of poly(ADP-ribose) polymerase interferes with Trypanosoma cruzi infection and proliferation of the parasite
-
Vilchez Larrea SC, Haikarainen T, Narwal M, Schlesinger M, Venkannagari H, et al. (2012) Inhibition of poly(ADP-ribose) polymerase interferes with Trypanosoma cruzi infection and proliferation of the parasite. PLoS One 7: e46063.
-
(2012)
PLoS One
, vol.7
-
-
Vilchez Larrea, S.C.1
Haikarainen, T.2
Narwal, M.3
Schlesinger, M.4
Venkannagari, H.5
-
66
-
-
4143132253
-
Trypanosoma cruzi and its components as exogenous mediators of inflammation recognized through Toll-like receptors
-
Campos MA, Gazzinelli RT, (2004) Trypanosoma cruzi and its components as exogenous mediators of inflammation recognized through Toll-like receptors. MediatorsInflamm 13: 139-143.
-
(2004)
MediatorsInflamm
, vol.13
, pp. 139-143
-
-
Campos, M.A.1
Gazzinelli, R.T.2
-
67
-
-
0031570514
-
Glycosylphosphatidylinositol-anchored mucin-like glycoproteins isolated from Trypanosoma cruzi trypomastigotes initiate the synthesis of proinflammatory cytokines by macrophages
-
Camargo MM, Almeida IC, Pereira ME, Ferguson MA, Travassos LR, et al. (1997) Glycosylphosphatidylinositol-anchored mucin-like glycoproteins isolated from Trypanosoma cruzi trypomastigotes initiate the synthesis of proinflammatory cytokines by macrophages. J Immunol 158: 5890-5901.
-
(1997)
J Immunol
, vol.158
, pp. 5890-5901
-
-
Camargo, M.M.1
Almeida, I.C.2
Pereira, M.E.3
Ferguson, M.A.4
Travassos, L.R.5
-
68
-
-
34249659491
-
Role of endogenous IFN-gamma in macrophage programming induced by IL-12 and IL-18
-
Bastos KR, Barboza R, Sardinha L, Russo M, Alvarez JM, et al. (2007) Role of endogenous IFN-gamma in macrophage programming induced by IL-12 and IL-18. J Interferon Cytokine Res 27: 399-410.
-
(2007)
J Interferon Cytokine Res
, vol.27
, pp. 399-410
-
-
Bastos, K.R.1
Barboza, R.2
Sardinha, L.3
Russo, M.4
Alvarez, J.M.5
|