IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 48, 2013, Pages

  Jakobsen, Martin R ^a   Bak, Rasmus O ^a   Andersen, Annika ^a   Berg, Randi K ^a,b   Jensen, Søren B ^a,c   Jin, Tengchuan ^d   Laustsen, Anders ^a   Hansen, Kathrine ^a   Østergaard, Lars ^b   Fitzgerald, Katherine A ^c   Xiao, T Sam ^d   Mikkelsen, Jacob G ^a   Mogensen, Trine H ^a   Paludan, Søren R ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Antiviral defense; DNA sensing; Innate immunity

Indexed keywords

BETA INTERFERON; INTERFERON INDUCIBLE PROTEIN 16; INTERFERON REGULATORY FACTOR; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 7; PHOSPHOTRANSFERASE; SINGLE STRANDED DNA; UNCLASSIFIED DRUG; VIRUS DNA;

ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE RESPONSE; CYTOPLASM; DNA STRUCTURE; GENE ACTIVATION; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOSTIMULATION; LENTIVIRINAE; MACROPHAGE; MOLECULAR SENSOR; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; VIRAL GENE DELIVERY SYSTEM; VIRUS CELL INTERACTION; VIRUS REPLICATION;

ANTIVIRAL DEFENSE; DNA SENSING; INNATE IMMUNITY;

DNA, VIRAL; GENE KNOCKDOWN TECHNIQUES; HIV-1; HUMANS; IMMUNITY, INNATE; IN SITU HYBRIDIZATION, FLUORESCENCE; MACROPHAGES; MEMBRANE PROTEINS; MICROSCOPY, CONFOCAL; NUCLEAR PROTEINS; PHOSPHOPROTEINS; SIGNAL TRANSDUCTION; VIRUS REPLICATION;

EID: 84888002403     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1311669110     Document Type: Article

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