Detection of prokaryotic mRNA signifies microbial viability and promotes immunity

Nature

Volumn 474, Issue 7351, 2011, Pages 385-392

  Sander, Leif E ^a   Davis, Michael J ^b   Boekschoten, Mark V ^c   Amsen, Derk ^d   Dascher, Christopher C ^a   Ryffel, Bernard ^e   Swanson, Joel A ^b   Müller, Michael ^c   Blander, J Magarian ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c WAGENINGEN UNIVERSITY   (Netherlands)

^d UNIVERSITY OF AMSTERDAM   (Netherlands)

^e CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL RNA; LIVE VACCINE; MESSENGER RNA; UNCLASSIFIED DRUG; VIABILITY ASSOCIATED PATHOGEN ASSOCIATED MOLECULAR PATTERN; VIRULENCE FACTOR;

ANTIBODY; BACTERIUM; BIOLOGICAL INVASION; DETECTION METHOD; GENETIC ANALYSIS; IMMUNE RESPONSE; IMMUNITY; INFECTIOUS DISEASE; MICROBIAL ACTIVITY; PATHOGENICITY; RISK FACTOR; VACCINATION; VIRULENCE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; IMMUNITY; INFECTION; INNATE IMMUNITY; MICROBIAL VIABILITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROKARYOTE;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; ANTIBODIES, BACTERIAL; BACTERIA; BACTERIAL VACCINES; CARRIER PROTEINS; CELLS, CULTURED; DENDRITIC CELLS; IMMUNITY, INNATE; INFLAMMASOMES; INTERFERON-BETA; MACROPHAGES; MICE; MICE, INBRED C57BL; MICROBIAL VIABILITY; PHAGOCYTOSIS; PHAGOSOMES; RNA, BACTERIAL; RNA, MESSENGER; VACCINES, ATTENUATED; VACCINES, INACTIVATED; VIRULENCE FACTORS;

BACTERIA (MICROORGANISMS); MAMMALIA; PROKARYOTA;

EID: 79959242498     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature10072     Document Type: Article

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