The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection

Nature Immunology

Volumn 16, Issue 5, 2015, Pages 467-475

  Man, Si Ming ^a,b   Karki, Rajendra ^a   Malireddi, R K Subbarao ^a   Neale, Geoffrey ^a   Vogel, Peter ^a   Yamamoto, Masahiro ^c   Lamkanfi, Mohamed ^d,e   Kanneganti, Thirumala Devi ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c OSAKA UNIVERSITY   (Japan)

^d DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^e GHENT UNIVERSITY   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; AIM2 INFLAMMASOME; BACTERIAL DNA; CASPASE 11; CYCLIC AMP; CYCLIC GMP; DOUBLE STRANDED DNA; GUANINE NUCLEOTIDE BINDING PROTEIN; INFLAMMASOME; INTERFERON REGULATORY FACTOR 1; UNCLASSIFIED DRUG; AIM2 PROTEIN, MOUSE; DNA; DNA BINDING PROTEIN; INTERFERON; IRF1 PROTEIN, MOUSE; MB21D1 PROTEIN, MOUSE; NUCLEOTIDYLTRANSFERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL STRAIN; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; DNA TRANSFECTION; ENZYME ACTIVATION; FEMALE; FRANCISELLA NOVICIDA; INFECTION CONTROL; INTRACELLULAR KILLING; MALE; MOUSE; MURINE CYTOMEGALOVIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; TULAREMIA; ANIMAL; BACTERIOLYSIS; CELL CULTURE; FRANCISELLA TULARENSIS; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY;

ANIMALS; BACTERIOLYSIS; CELLS, CULTURED; DNA; DNA, BACTERIAL; DNA-BINDING PROTEINS; FRANCISELLA TULARENSIS; GENE EXPRESSION REGULATION; GTP-BINDING PROTEINS; INFLAMMASOMES; INTERFERON REGULATORY FACTOR-1; INTERFERON TYPE I; MICE; MICE, KNOCKOUT; NUCLEOTIDYLTRANSFERASES; TULAREMIA;

EID: 84928545520     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3118     Document Type: Article

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