An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells

Science

Volumn 352, Issue 6290, 2016, Pages 1232-1236

  Zanoni, Ivan ^a,b,c   Tan, Yunhao ^a   Gioia, Marco Di ^a   Broggi, Achille ^a   Ruan, Jianbin ^f   Shi, Jianjin ^e   Donado, Carlos A ^a   Shao, Feng ^e   Wu, Hao ^a,f   Springstead, James R ^d   Kagan, Jonathan C ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF MILANO BICOCCA   (Italy)

^c HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^d Parkview Campus   (United States)

^e NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES   (China)

^f HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CASPASE 11; INFLAMMASOME; INTERLEUKIN 1; INTERLEUKIN 1BETA; PHOSPHOLIPID; CARRIER PROTEIN; CASP11 PROTEIN, MOUSE; CASPASE; CIAS1 PROTEIN, MOUSE; LIPOPOLYSACCHARIDE; PATTERN RECOGNITION RECEPTOR; TLR4 PROTEIN, MOUSE; TOLL LIKE RECEPTOR 4;

CELLS AND CELL COMPONENTS; ENZYME; ENZYME ACTIVITY; IMMUNE SYSTEM; IMMUNITY; LIGAND; MICROORGANISM; PATTERN RECOGNITION;

ADAPTIVE IMMUNITY; ARTICLE; CELL ACTIVATION; CELL ISOLATION; CYTOKINE RELEASE; DENDRITIC CELL; ENZYME ACTIVITY; INNATE IMMUNITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DOMAIN; AGONISTS; ANIMAL; CELL DEATH; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MOUSE;

BACTERIA (MICROORGANISMS);

ADAPTIVE IMMUNITY; ANIMALS; CARRIER PROTEINS; CASPASES; CELL DEATH; DENDRITIC CELLS; IMMUNITY, INNATE; INFLAMMASOMES; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MICE; MICE, KNOCKOUT; PHOSPHOLIPIDS; RECEPTORS, PATTERN RECOGNITION; TOLL-LIKE RECEPTOR 4;

EID: 84964434465     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aaf3036     Document Type: Article

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