Reactive Oxygen Species Regulate Caspase-11 Expression and Activation of the Non-canonical NLRP3 Inflammasome during Enteric Pathogen Infection

PLoS Pathogens

Volumn 10, Issue 9, 2014, Pages

  Lupfer, Christopher R ^a   Anand, Paras K ^a   Liu, Zhiping ^a   Stokes, Kate L ^a   Vogel, Peter ^a   Lamkanfi, Mohamed ^b,c   Kanneganti, Thirumala Devi ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b Vlaams Instituut voor Biotechnologie   (Belgium)

^c GHENT UNIVERSITY   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 11; CRYOPYRIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERLEUKIN 18; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; CARD15 PROTEIN, MOUSE; CARRIER PROTEIN; CASP11 PROTEIN, MOUSE; CASPASE; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CIAS1 PROTEIN, MOUSE; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RIPK2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHAGY; BACTERIAL INFECTION; CELL DEATH; CITROBACTER RODENTIUM; CONTROLLED STUDY; ENZYME ACTIVATION; GENETIC ANALYSIS; IMMUNE RESPONSE; INFLAMMATION; MOUSE; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; QUANTITATIVE ASSAY; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; COLITIS; ENTEROBACTERIACEAE INFECTION; FEMALE; IMMUNOLOGY; KNOCKOUT MOUSE; MACROPHAGE; MALE; METABOLISM; MICROBIOLOGY; NONOBESE DIABETIC MOUSE; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CARRIER PROTEINS; CASPASES; CITROBACTER RODENTIUM; COLITIS; ENTEROBACTERIACEAE INFECTIONS; FEMALE; INFLAMMASOMES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; MICE, KNOCKOUT; NOD2 SIGNALING ADAPTOR PROTEIN; REACTIVE OXYGEN SPECIES; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION;

EID: 84907584408     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004410     Document Type: Article

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