Pathogenic Vibrio activate NLRP3 inflammasome via cytotoxins and TLR/nucleotide-binding oligomerization domain-mediated NF-κB signaling

Journal of Immunology

Volumn 184, Issue 9, 2010, Pages 5287-5297

  Toma, Claudia ^a   Higa, Naomi ^a   Koizumi, Yukiko ^a   Nakasone, Noboru ^a   Ogura, Yasunori ^a   McCoy, Andrea J ^a,h   Franchi, Luigi ^f   Uematsu, Satoshi ^b   Sagara, Junji ^c   Taniguchi, Shun'ichiro ^d   Tsutsui, Hiroko ^e   Akira, Shizuo ^b   Tschopp, Jürg ^g   Núñez, Gabriel ^f   Suzuki, Toshihiko ^a  

^a UNIVERSITY OF THE RYUKYUS   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c SHINSHU UNIVERSITY   (Japan)

^d SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e HYOGO COLLEGE OF MEDICINE   (Japan)

^f UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^g UNIVERSITY OF LAUSANNE   (Switzerland)

^h NAVAL MEDICAL RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; CASPASE RECRUITMENT DOMAIN PROTEIN 4; CRYOPYRIN; CYTOTOXIN; HEMOLYSIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; TOLL LIKE RECEPTOR; BACTERIAL TOXIN; CARD15 PROTEIN, MOUSE; CARD4 PROTEIN, MOUSE; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; LIGAND;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENDOTOXIN DETECTION; ENZYME ACTIVATION; GENETIC TRANSFECTION; MACROPHAGE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; VIBRIO CHOLERAE; VIBRIO VULNIFICUS; VIBRIO VULNIFICUS INFECTION; VIBRIOSIS; ANIMAL; BONE MARROW CELL; C57BL MOUSE; ENZYMOLOGY; GENETICS; IMMUNOLOGY; INFLAMMATION; INNATE IMMUNITY; METABOLISM; MICROBIOLOGY; MOUSE MUTANT; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY; SECRETION;

ANIMALS; BACTERIAL TOXINS; BONE MARROW CELLS; CARRIER PROTEINS; CASPASE 1; IMMUNITY, INNATE; INFLAMMATION; INTERLEUKIN-1BETA; LIGANDS; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NF-KAPPA B; NOD1 SIGNALING ADAPTOR PROTEIN; NOD2 SIGNALING ADAPTOR PROTEIN; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS; VIBRIO CHOLERAE; VIBRIO VULNIFICUS;

EID: 77954521853     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0903536     Document Type: Article

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