Activation of interferon-γ inducing factor mediated by interleukin-1β converting enzyme

Science

Volumn 275, Issue 5297, 1997, Pages 206-209

  Gu, Yong ^a   Kuida, Keisuke ^b   Tsutsui, Hiroko ^c   Ku, George ^a   Hsiao, Kathy ^a   Fleming, Mark A ^a   Hayashi, Nobuki ^c   Higashino, Kazuya ^c   Okamura, Haruki ^c   Nakanishi, Kenji ^c   Kurimoto, Masashi ^d   Tanimoto, Tadao ^d   Flavell, Richard A ^e   Sato, Vicki ^a   Harding, Matthew W ^a   Livingston, David J ^a   Su, Michael S S ^a  

^a VERTEX PHARMACEUTICALS   (United States)

^b TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^c HYOGO COLLEGE OF MEDICINE   (Japan)

^d HAYASHIBARA BIOCHEMICAL LABORATORIES INC   (Japan)

^e YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; GAMMA INTERFERON; INTERFERON INDUCING AGENT; INTERLEUKIN 1BETA CONVERTING ENZYME; PROTEIN PRECURSOR; RECOMBINANT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL LINE; CELL STIMULATION; GENE EXPRESSION; IMMUNOPRECIPITATION; KUPFFER CELL; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROPIONIBACTERIUM ACNES; PROTEIN DEGRADATION; PROTEIN PROCESSING; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; SEPTIC SHOCK;

ANIMALS; CASPASE 1; CASPASE 3; CASPASES; CASPASES, INITIATOR; COS CELLS; CULTURE MEDIA, CONDITIONED; CYSTEINE ENDOPEPTIDASES; CYTOKINES; HUMANS; INTERFERON TYPE II; INTERLEUKIN-18; KUPFFER CELLS; LIPOPOLYSACCHARIDES; MICE; PROTEIN PRECURSORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; SPLEEN; TRANSFECTION;

ANIMALIA; BACTERIA (MICROORGANISMS); CORYNEBACTERIUM; PROPIONIBACTERIUM ACNES;

EID: 15644369352     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.275.5297.206     Document Type: Article

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