Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome

Nature

Volumn 513, Issue 7517, 2014, Pages 237-241

  Xu, Hao ^a   Yang, Jieling ^a,b   Gao, Wenqing ^a   Li, Lin ^a   Li, Peng ^a   Zhang, Li ^a   Gong, Yi Nan ^a   Peng, Xiaolan ^a   Xi, Jianzhong Jeff ^c   Chen, She ^a   Wang, Fengchao ^a   Shao, Feng ^a,b  

^a NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES   (China)

^b INSTITUTE OF BIOPHYSICS   (China)

^c PEKING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIN; GLUCOSYLTRANSFERASE; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; PYRIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; VIRULENCE FACTOR; BACTERIAL PROTEIN; BACTERIAL TOXIN; CYTOSKELETON PROTEIN; MARENOSTRIN; PATTERN RECOGNITION RECEPTOR; TOXB PROTEIN, CLOSTRIDIUM DIFFICILE;

BACTERIUM; DIARRHEAL DISEASE; ENZYME ACTIVITY; IMMUNE SYSTEM; INFECTIVITY; INNATE BEHAVIOR; MAMMAL; MUTATION; PATHOGEN; PROTEIN; TOXIN;

ACTIN FILAMENT; ADENOSINE DIPHOSPHATE RIBOSYLATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL INFECTION; BACTERIUM CULTURE; BURKHOLDERIA CENOCEPACIA; CLOSTRIDIUM BOTULINUM; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INACTIVATION; FAMILIAL MEDITERRANEAN FEVER; GLYCOSYLATION; HISTOPHILUS SOMNI; HOSPITAL INFECTION; HUMAN; HUMAN CELL; INFECTIOUS DIARRHEA; INNATE IMMUNITY; MALE; MOUSE; NONHUMAN; PEPTOCLOSTRIDIUM DIFFICILE; PNEUMONIA; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN MODIFICATION; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM; SHIGELLA FLEXNERI; TYPE VI SECRETION SYSTEM; VIBRIO PARAHAEMOLYTICUS; ANIMAL; CELL LINE; CLOSTRIDIUM DIFFICILE; GENETICS; IMMUNOLOGY; INBRED MOUSE STRAIN; METABOLISM; MUTATION; U937 CELL LINE;

BACTERIA (MICROORGANISMS); BURKHOLDERIA CENOCEPACIA; CLOSTRIDIUM BOTULINUM; CLOSTRIDIUM DIFFICILE; HISTOPHILUS SOMNI; MAMMALIA; MUS; VIBRIO PARAHAEMOLYTICUS;

ANIMALS; BACTERIAL PROTEINS; BACTERIAL TOXINS; BURKHOLDERIA CENOCEPACIA; CASPASE 1; CELL LINE; CLOSTRIDIUM DIFFICILE; CYTOSKELETAL PROTEINS; HUMANS; IMMUNITY, INNATE; INFLAMMASOMES; MICE; MICE, INBRED STRAINS; MUTATION; PROTEIN BINDING; RECEPTORS, PATTERN RECOGNITION; RHO GTP-BINDING PROTEINS; U937 CELLS;

EID: 84907270863     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13449     Document Type: Article

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