DAI Senses Influenza A Virus Genomic RNA and Activates RIPK3-Dependent Cell Death

Cell Host and Microbe

Volumn 20, Issue 5, 2016, Pages 674-681

  Thapa, Roshan J ^a   Ingram, Justin P ^a   Ragan, Katherine B ^b   Nogusa, Shoko ^a   Boyd, David F ^c   Benitez, Asiel A ^d   Sridharan, Haripriya ^b   Kosoff, Rachelle ^a   Shubina, Maria ^a   Landsteiner, Vanessa J ^b   Andrake, Mark ^a   Vogel, Peter ^c   Sigal, Luis J ^e   tenOever, Benjamin R ^d   Thomas, Paul G ^c   Upton, Jason W ^b   Balachandran, Siddharth ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^e THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOHEXIMIDE; GENOMIC RNA; NONSTRUCTURAL PROTEIN 1; RIPK1 PROTEIN; UNCLASSIFIED DRUG; VIRAL PROTEIN; GLYCOPROTEIN; MLKL PROTEIN, MOUSE; PROTEIN KINASE; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RIPK1 PROTEIN, MOUSE; RIPK3 PROTEIN, MOUSE; VIRUS RNA; ZBP1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOPLASM; EMBRYO; ENZYME ACTIVATION; INFLUENZA A VIRUS; MOUSE; NECROPTOSIS; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION; ANIMAL; CELL DEATH; CELL LINE; DEFICIENCY; GENE INACTIVATION; GENOMICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MUTATION;

ANIMALS; CELL DEATH; CELL LINE; GENE KNOCKOUT TECHNIQUES; GENOMICS; GLYCOPROTEINS; HOST-PATHOGEN INTERACTIONS; INFLUENZA A VIRUS; MICE; MICE, KNOCKOUT; MUTATION; PROTEIN KINASES; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; RNA, VIRAL;

EID: 84994731750     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2016.09.014     Document Type: Article

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