Impaired mitochondrial energy metabolism in Alzheimer's disease: Impact on pathogenesis via disturbed epigenetic regulation of chromatin landscape

Progress in Neurobiology

Volumn 131, Issue , 2015, Pages 1-20

  Salminen, Antero ^a   Haapasalo, Annakaisa ^a,b   Kauppinen, Anu ^a,b   Kaarniranta, Kai ^a,b   Soininen, Hilkka ^a,b   Hiltunen, Mikko ^a,b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

Epigenetics; Histone acetylation; Histone methylation; Krebs cycle; Mitochondrial dynamics; Retrograde signaling

Indexed keywords

2 OXOGLUTARIC ACID; ACETYL COENZYME A; AMYLOID BETA PROTEIN; CITRIC ACID; FUMARIC ACID; HISTONE DEMETHYLASE; OXOGLUTARATE DEHYDROGENASE; SUCCINIC ACID; TAU PROTEIN; CHROMATIN;

ALZHEIMER DISEASE; CHROMATIN; CITRIC ACID CYCLE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA METHYLATION; ENERGY METABOLISM; ENZYME INHIBITION; EPIGENETICS; GENE EXPRESSION; HISTONE ACETYLATION; HISTONE METHYLATION; HUMAN; HYPOXIA; MITOCHONDRIAL DYNAMICS; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; REVIEW; ANIMAL; GENETIC EPIGENESIS; GENETICS; METABOLISM; MITOCHONDRION; PHYSIOLOGY;

ALZHEIMER DISEASE; ANIMALS; CHROMATIN; DNA METHYLATION; ENERGY METABOLISM; EPIGENESIS, GENETIC; HUMANS; MITOCHONDRIA;

EID: 84938203544     PISSN: 03010082     EISSN: 18735118     Source Type: Journal    
DOI: 10.1016/j.pneurobio.2015.05.001     Document Type: Review

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