메뉴 건너뛰기




Volumn 8, Issue , 2011, Pages

Pro-inflammatory gene expression and neurotoxic effects of activated microglia are attenuated by absence of CCAAT/enhancer binding protein β

Author keywords

[No Author keywords available]

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; CCAAT ENHANCER BINDING PROTEIN BETA; CD11B ANTIGEN; GAMMA INTERFERON; GLIAL FIBRILLARY ACIDIC PROTEIN; LIPOPOLYSACCHARIDE; MICROTUBULE ASSOCIATED PROTEIN 2; CYTOKINE; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NOS2 PROTEIN, MOUSE;

EID: 81055150384     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-8-156     Document Type: Article
Times cited : (77)

References (60)
  • 1
    • 67349251479 scopus 로고    scopus 로고
    • Characterization of the microglial phenotype under specific pro-inflammatory and anti-inflammatory conditions: Effects of oligomeric and fibrillar amyloid-beta
    • 10.1016/j.jneuroim.2009.02.003, 19269040
    • Michelucci A, Heurtaux T, Grandbarbe L, Morga E, Heuschling P. Characterization of the microglial phenotype under specific pro-inflammatory and anti-inflammatory conditions: Effects of oligomeric and fibrillar amyloid-beta. J Neuroimmunol 2009, 210:3-12. 10.1016/j.jneuroim.2009.02.003, 19269040.
    • (2009) J Neuroimmunol , vol.210 , pp. 3-12
    • Michelucci, A.1    Heurtaux, T.2    Grandbarbe, L.3    Morga, E.4    Heuschling, P.5
  • 3
    • 24944586421 scopus 로고    scopus 로고
    • Signaling via NF-kappaB in the nervous system
    • 10.1016/j.bbamcr.2005.05.009, 15993497
    • Kaltschmidt B, Widera D, Kaltschmidt C. Signaling via NF-kappaB in the nervous system. Biochim Biophys Acta 2005, 1745:287-299. 10.1016/j.bbamcr.2005.05.009, 15993497.
    • (2005) Biochim Biophys Acta , vol.1745 , pp. 287-299
    • Kaltschmidt, B.1    Widera, D.2    Kaltschmidt, C.3
  • 4
    • 1242314376 scopus 로고    scopus 로고
    • Induction of chemokines in human astrocytes by picornavirus infection requires activation of both AP-1 and NF-kappa B
    • 10.1002/glia.10331, 14730702
    • Kwon D, Fuller AC, Palma JP, Choi IH, Kim BS. Induction of chemokines in human astrocytes by picornavirus infection requires activation of both AP-1 and NF-kappa B. Glia 2004, 45:287-296. 10.1002/glia.10331, 14730702.
    • (2004) Glia , vol.45 , pp. 287-296
    • Kwon, D.1    Fuller, A.C.2    Palma, J.P.3    Choi, I.H.4    Kim, B.S.5
  • 5
    • 0037174916 scopus 로고    scopus 로고
    • JAK-STAT signaling mediates gangliosides-induced inflammatory responses in brain microglial cells
    • 10.1074/jbc.M203885200, 12191995
    • Kim OS, Park EJ, Joe EH, Jou I. JAK-STAT signaling mediates gangliosides-induced inflammatory responses in brain microglial cells. J Biol Chem 2002, 277:40594-40601. 10.1074/jbc.M203885200, 12191995.
    • (2002) J Biol Chem , vol.277 , pp. 40594-40601
    • Kim, O.S.1    Park, E.J.2    Joe, E.H.3    Jou, I.4
  • 6
    • 43049173715 scopus 로고    scopus 로고
    • Hypoxia enhances CXCR4 expression favoring microglia migration via HIF-1alpha activation
    • 10.1016/j.bbrc.2008.04.055, 18435916
    • Wang X, Li C, Chen Y, Hao Y, Zhou W, Chen C, Yu Z. Hypoxia enhances CXCR4 expression favoring microglia migration via HIF-1alpha activation. Biochem Biophys Res Commun 2008, 371:283-288. 10.1016/j.bbrc.2008.04.055, 18435916.
    • (2008) Biochem Biophys Res Commun , vol.371 , pp. 283-288
    • Wang, X.1    Li, C.2    Chen, Y.3    Hao, Y.4    Zhou, W.5    Chen, C.6    Yu, Z.7
  • 7
    • 33646117271 scopus 로고    scopus 로고
    • Evidence that hypoxia-inducible factor-1 (HIF-1) mediates transcriptional activation of interleukin-1beta (IL-1beta) in astrocyte cultures
    • 10.1016/j.jneuroim.2006.01.014, 16504308
    • Zhang W, Petrovic JM, Callaghan D, Jones A, Cui H, Howlett C, Stanimirovic D. Evidence that hypoxia-inducible factor-1 (HIF-1) mediates transcriptional activation of interleukin-1beta (IL-1beta) in astrocyte cultures. J Neuroimmunol 2006, 174:63-73. 10.1016/j.jneuroim.2006.01.014, 16504308.
    • (2006) J Neuroimmunol , vol.174 , pp. 63-73
    • Zhang, W.1    Petrovic, J.M.2    Callaghan, D.3    Jones, A.4    Cui, H.5    Howlett, C.6    Stanimirovic, D.7
  • 8
    • 78349284376 scopus 로고    scopus 로고
    • The P2X7-Egr pathway regulates nucleotide-dependent inflammatory gene expression in microglia
    • 10.1002/glia.21071, 20878769
    • Friedle SA, Brautigam VM, Nikodemova M, Wright ML, Watters JJ. The P2X7-Egr pathway regulates nucleotide-dependent inflammatory gene expression in microglia. Glia 2011, 59:1-13. 10.1002/glia.21071, 20878769.
    • (2011) Glia , vol.59 , pp. 1-13
    • Friedle, S.A.1    Brautigam, V.M.2    Nikodemova, M.3    Wright, M.L.4    Watters, J.J.5
  • 9
    • 0033557359 scopus 로고    scopus 로고
    • The transcription factor interferon regulatory factor 1 is expressed after cerebral ischemia and contributes to ischemic brain injury
    • 10.1084/jem.189.4.719, 2192924, 9989987
    • Iadecola C, Salkowski CA, Zhang F, Aber T, Nagayama M, Vogel SN, Ross ME. The transcription factor interferon regulatory factor 1 is expressed after cerebral ischemia and contributes to ischemic brain injury. J Exp Med 1999, 189:719-727. 10.1084/jem.189.4.719, 2192924, 9989987.
    • (1999) J Exp Med , vol.189 , pp. 719-727
    • Iadecola, C.1    Salkowski, C.A.2    Zhang, F.3    Aber, T.4    Nagayama, M.5    Vogel, S.N.6    Ross, M.E.7
  • 10
    • 33745000762 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor agonist regulation of glial activation: relevance to CNS inflammatory disorders
    • 10.1016/j.neuint.2006.04.003, 16753239
    • Drew PD, Xu J, Storer PD, Chavis JA, Racke MK. Peroxisome proliferator-activated receptor agonist regulation of glial activation: relevance to CNS inflammatory disorders. Neurochem Int 2006, 49:183-189. 10.1016/j.neuint.2006.04.003, 16753239.
    • (2006) Neurochem Int , vol.49 , pp. 183-189
    • Drew, P.D.1    Xu, J.2    Storer, P.D.3    Chavis, J.A.4    Racke, M.K.5
  • 12
    • 0037996661 scopus 로고    scopus 로고
    • Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress
    • Shih AY, Johnson DA, Wong G, Kraft AD, Jiang L, Erb H, Johnson JA, Murphy TH. Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress. J Neurosci 2003, 23:3394-3406.
    • (2003) J Neurosci , vol.23 , pp. 3394-3406
    • Shih, A.Y.1    Johnson, D.A.2    Wong, G.3    Kraft, A.D.4    Jiang, L.5    Erb, H.6    Johnson, J.A.7    Murphy, T.H.8
  • 13
    • 0027214319 scopus 로고
    • CCAAT/enhancer-binding protein mRNA is translated into multiple proteins with different transcription activation potentials
    • 10.1073/pnas.90.17.8219, 47320, 8367486
    • Ossipow V, Descombes P, Schibler U. CCAAT/enhancer-binding protein mRNA is translated into multiple proteins with different transcription activation potentials. Proc Natl Acad Sci USA 1993, 90:8219-8223. 10.1073/pnas.90.17.8219, 47320, 8367486.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8219-8223
    • Ossipow, V.1    Descombes, P.2    Schibler, U.3
  • 14
    • 0032588390 scopus 로고    scopus 로고
    • C/EBPalpha regulates generation of C/EBPbeta isoforms through activation of specific proteolytic cleavage
    • 83963, 10022857
    • Welm AL, Timchenko NA, Darlington GJ. C/EBPalpha regulates generation of C/EBPbeta isoforms through activation of specific proteolytic cleavage. Mol Cell Biol 1999, 19:1695-1704. 83963, 10022857.
    • (1999) Mol Cell Biol , vol.19 , pp. 1695-1704
    • Welm, A.L.1    Timchenko, N.A.2    Darlington, G.J.3
  • 15
    • 0032167730 scopus 로고    scopus 로고
    • CCAAT enhancer- binding protein beta is required for normal hepatocyte proliferation in mice after partial hepatectomy
    • 10.1172/JCI3135, 508965, 9727068
    • Greenbaum LE, Li W, Cressman DE, Peng Y, Ciliberto G, Poli V, Taub R. CCAAT enhancer- binding protein beta is required for normal hepatocyte proliferation in mice after partial hepatectomy. J Clin Invest 1998, 102:996-1007. 10.1172/JCI3135, 508965, 9727068.
    • (1998) J Clin Invest , vol.102 , pp. 996-1007
    • Greenbaum, L.E.1    Li, W.2    Cressman, D.E.3    Peng, Y.4    Ciliberto, G.5    Poli, V.6    Taub, R.7
  • 16
    • 0036683653 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding proteins: structure, function and regulation
    • 1222736, 12006103
    • Ramji DP, Foka P. CCAAT/enhancer-binding proteins: structure, function and regulation. Biochem J 2002, 365:561-575. 1222736, 12006103.
    • (2002) Biochem J , vol.365 , pp. 561-575
    • Ramji, D.P.1    Foka, P.2
  • 17
    • 0032491401 scopus 로고    scopus 로고
    • The role of C/EBP isoforms in the control of inflammatory and native immunity functions
    • 10.1074/jbc.273.45.29279, 9792624
    • Poli V. The role of C/EBP isoforms in the control of inflammatory and native immunity functions. J Biol Chem 1998, 273:29279-29282. 10.1074/jbc.273.45.29279, 9792624.
    • (1998) J Biol Chem , vol.273 , pp. 29279-29282
    • Poli, V.1
  • 18
    • 0035966082 scopus 로고    scopus 로고
    • The induction of cyclooxygenase-2 mRNA in macrophages is biphasic and requires both CCAAT enhancer-binding protein beta (C/EBP beta) and C/EBP delta transcription factors
    • 10.1074/jbc.M108282200, 11668179
    • Caivano M, Gorgoni B, Cohen P, Poli V. The induction of cyclooxygenase-2 mRNA in macrophages is biphasic and requires both CCAAT enhancer-binding protein beta (C/EBP beta) and C/EBP delta transcription factors. J Biol Chem 2001, 276:48693-48701. 10.1074/jbc.M108282200, 11668179.
    • (2001) J Biol Chem , vol.276 , pp. 48693-48701
    • Caivano, M.1    Gorgoni, B.2    Cohen, P.3    Poli, V.4
  • 19
    • 0027368278 scopus 로고
    • Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide
    • 10.1073/pnas.90.20.9730, 47644, 7692452
    • Lowenstein CJ, Alley EW, Raval P, Snowman AM, Snyder SH, Russell SW, Murphy WJ. Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide. Proc Natl Acad Sci USA 1993, 90:9730-9734. 10.1073/pnas.90.20.9730, 47644, 7692452.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 9730-9734
    • Lowenstein, C.J.1    Alley, E.W.2    Raval, P.3    Snowman, A.M.4    Snyder, S.H.5    Russell, S.W.6    Murphy, W.J.7
  • 20
    • 0034603122 scopus 로고    scopus 로고
    • Transcriptional regulation of the cyclooxygenase-2 gene in activated mast cells
    • 10.1074/jbc.275.5.3107, 10652293
    • Reddy ST, Wadleigh DJ, Herschman HR. Transcriptional regulation of the cyclooxygenase-2 gene in activated mast cells. J Biol Chem 2000, 275:3107-3113. 10.1074/jbc.275.5.3107, 10652293.
    • (2000) J Biol Chem , vol.275 , pp. 3107-3113
    • Reddy, S.T.1    Wadleigh, D.J.2    Herschman, H.R.3
  • 21
    • 0038111991 scopus 로고    scopus 로고
    • C/EBPbeta regulation in lipopolysaccharide-stimulated macrophages
    • 10.1128/MCB.23.14.4841-4858.2003, 162211, 12832471
    • Bradley MN, Zhou L, Smale ST. C/EBPbeta regulation in lipopolysaccharide-stimulated macrophages. Mol Cell Biol 2003, 23:4841-4858. 10.1128/MCB.23.14.4841-4858.2003, 162211, 12832471.
    • (2003) Mol Cell Biol , vol.23 , pp. 4841-4858
    • Bradley, M.N.1    Zhou, L.2    Smale, S.T.3
  • 22
    • 0033988811 scopus 로고    scopus 로고
    • Pro-inflammatory cytokines induce the transcription factors C/EBPbeta and C/EBPdelta in astrocytes
    • 10.1002/(SICI)1098-1136(20000101)29:1<91::AID-GLIA9>3.0.CO;2-I, 10594926
    • Cardinaux JR, Allaman I, Magistretti PJ. Pro-inflammatory cytokines induce the transcription factors C/EBPbeta and C/EBPdelta in astrocytes. Glia 2000, 29:91-97. 10.1002/(SICI)1098-1136(20000101)29:1<91::AID-GLIA9>3.0.CO;2-I, 10594926.
    • (2000) Glia , vol.29 , pp. 91-97
    • Cardinaux, J.R.1    Allaman, I.2    Magistretti, P.J.3
  • 23
    • 0029927345 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide, pituitary adenylate cyclase-activating peptide, and noradrenaline induce the transcription factors CCAAT/enhancer binding protein (C/EBP)-beta and C/EBP delta in mouse cortical astrocytes: involvement in cAMP-regulated glycogen metabolism
    • Cardinaux JR, Magistretti PJ. Vasoactive intestinal peptide, pituitary adenylate cyclase-activating peptide, and noradrenaline induce the transcription factors CCAAT/enhancer binding protein (C/EBP)-beta and C/EBP delta in mouse cortical astrocytes: involvement in cAMP-regulated glycogen metabolism. J Neurosci 1996, 16:919-929.
    • (1996) J Neurosci , vol.16 , pp. 919-929
    • Cardinaux, J.R.1    Magistretti, P.J.2
  • 24
    • 33845948245 scopus 로고    scopus 로고
    • Upregulation of CCAAT/enhancer binding protein beta in activated astrocytes and microglia
    • 10.1002/glia.20446, 17078024
    • Ejarque-Ortiz A, Medina MG, Tusell JM, Perez-Gonzalez AP, Serratosa J, Saura J. Upregulation of CCAAT/enhancer binding protein beta in activated astrocytes and microglia. Glia 2007, 55:178-188. 10.1002/glia.20446, 17078024.
    • (2007) Glia , vol.55 , pp. 178-188
    • Ejarque-Ortiz, A.1    Medina, M.G.2    Tusell, J.M.3    Perez-Gonzalez, A.P.4    Serratosa, J.5    Saura, J.6
  • 25
    • 33750507923 scopus 로고    scopus 로고
    • Expression of C/EBPalpha and C/EBPbeta in glial cells in vitro after inducing glial activation by different stimuli
    • 10.1016/j.neulet.2006.09.078, 17070994
    • Perez-Capote K, Saura J, Serratosa J, Sola C. Expression of C/EBPalpha and C/EBPbeta in glial cells in vitro after inducing glial activation by different stimuli. Neurosci Lett 2006, 410:25-30. 10.1016/j.neulet.2006.09.078, 17070994.
    • (2006) Neurosci Lett , vol.410 , pp. 25-30
    • Perez-Capote, K.1    Saura, J.2    Serratosa, J.3    Sola, C.4
  • 26
    • 33748089027 scopus 로고    scopus 로고
    • Decreased brain damage and curtailed inflammation in transcription factor CCAAT/enhancer binding protein beta knockout mice following transient focal cerebral ischemia
    • 10.1111/j.1471-4159.2006.04056.x, 16899075
    • Kapadia R, Tureyen K, Bowen KK, Kalluri H, Johnson PF, Vemuganti R. Decreased brain damage and curtailed inflammation in transcription factor CCAAT/enhancer binding protein beta knockout mice following transient focal cerebral ischemia. J Neurochem 2006, 98:1718-1731. 10.1111/j.1471-4159.2006.04056.x, 16899075.
    • (2006) J Neurochem , vol.98 , pp. 1718-1731
    • Kapadia, R.1    Tureyen, K.2    Bowen, K.K.3    Kalluri, H.4    Johnson, P.F.5    Vemuganti, R.6
  • 27
    • 44449098672 scopus 로고    scopus 로고
    • CCAAT/enhancer binding protein beta deficiency provides cerebral protection following excitotoxic injury
    • 10.1242/jcs.025031, 18388310
    • Cortes-Canteli M, Luna-Medina R, Sanz-Sancristobal M, Alvarez-Barrientos A, Santos A, Perez-Castillo A. CCAAT/enhancer binding protein beta deficiency provides cerebral protection following excitotoxic injury. J Cell Sci 2008, 121:1224-1234. 10.1242/jcs.025031, 18388310.
    • (2008) J Cell Sci , vol.121 , pp. 1224-1234
    • Cortes-Canteli, M.1    Luna-Medina, R.2    Sanz-Sancristobal, M.3    Alvarez-Barrientos, A.4    Santos, A.5    Perez-Castillo, A.6
  • 29
    • 0022922108 scopus 로고
    • Characterization of ameboid microglia isolated from developing mammalian brain
    • Giulian D, Baker TJ. Characterization of ameboid microglia isolated from developing mammalian brain. J Neurosci 1986, 6:2163-2178.
    • (1986) J Neurosci , vol.6 , pp. 2163-2178
    • Giulian, D.1    Baker, T.J.2
  • 30
    • 0344013138 scopus 로고    scopus 로고
    • High-yield isolation of murine microglia by mild trypsinization
    • 10.1002/glia.10274, 14603460
    • Saura J, Tusell JM, Serratosa J. High-yield isolation of murine microglia by mild trypsinization. Glia 2003, 44:183-189. 10.1002/glia.10274, 14603460.
    • (2003) Glia , vol.44 , pp. 183-189
    • Saura, J.1    Tusell, J.M.2    Serratosa, J.3
  • 31
    • 78651284870 scopus 로고    scopus 로고
    • Inhibition of CCAAT/enhancer binding protein delta expression by chrysin in microglial cells results in anti-inflammatory and neuroprotective effects
    • 10.1111/j.1471-4159.2010.06952.x, 20722966
    • Gresa-Arribas N, Serratosa J, Saura J, Sola C. Inhibition of CCAAT/enhancer binding protein delta expression by chrysin in microglial cells results in anti-inflammatory and neuroprotective effects. J Neurochem 2010, 115:526-536. 10.1111/j.1471-4159.2010.06952.x, 20722966.
    • (2010) J Neurochem , vol.115 , pp. 526-536
    • Gresa-Arribas, N.1    Serratosa, J.2    Saura, J.3    Sola, C.4
  • 32
    • 0038810288 scopus 로고    scopus 로고
    • Microglial apolipoprotein E and astroglial apolipoprotein J expression in vitro: opposite effects of lipopolysaccharide
    • 10.1046/j.1471-4159.2003.01788.x, 12787065
    • Saura J, Petegnief V, Wu X, Liang Y, Paul SM. Microglial apolipoprotein E and astroglial apolipoprotein J expression in vitro: opposite effects of lipopolysaccharide. J Neurochem 2003, 85:1455-1467. 10.1046/j.1471-4159.2003.01788.x, 12787065.
    • (2003) J Neurochem , vol.85 , pp. 1455-1467
    • Saura, J.1    Petegnief, V.2    Wu, X.3    Liang, Y.4    Paul, S.M.5
  • 33
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • 10.1006/meth.2001.1262, 11846609
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25:402-408. 10.1006/meth.2001.1262, 11846609.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 34
    • 77956600971 scopus 로고    scopus 로고
    • DNA methylation and Yin Yang-1 repress adenosine A2A receptor levels in human brain
    • 10.1111/j.1471-4159.2010.06928.x, 20666933
    • Buira SP, Dentesano G, Albasanz JL, Moreno J, Martin M, Ferrer I, Barrachina M. DNA methylation and Yin Yang-1 repress adenosine A2A receptor levels in human brain. J Neurochem 2010, 115:283-295. 10.1111/j.1471-4159.2010.06928.x, 20666933.
    • (2010) J Neurochem , vol.115 , pp. 283-295
    • Buira, S.P.1    Dentesano, G.2    Albasanz, J.L.3    Moreno, J.4    Martin, M.5    Ferrer, I.6    Barrachina, M.7
  • 35
    • 0037769043 scopus 로고    scopus 로고
    • Functional cooperation of simian virus 40 promoter factor 1 and CCAAT/enhancer-binding protein beta and delta in lipopolysaccharide-induced gene activation of IL-10 in mouse macrophages
    • Liu YW, Tseng HP, Chen LC, Chen BK, Chang WC. Functional cooperation of simian virus 40 promoter factor 1 and CCAAT/enhancer-binding protein beta and delta in lipopolysaccharide-induced gene activation of IL-10 in mouse macrophages. J Immunol 2003, 171:821-828.
    • (2003) J Immunol , vol.171 , pp. 821-828
    • Liu, Y.W.1    Tseng, H.P.2    Chen, L.C.3    Chen, B.K.4    Chang, W.C.5
  • 36
    • 77950363010 scopus 로고    scopus 로고
    • Mechanisms underlying inflammation in neurodegeneration
    • 10.1016/j.cell.2010.02.016, 2873093, 20303880
    • Glass CK, Saijo K, Winner B, Marchetto MC, Gage FH. Mechanisms underlying inflammation in neurodegeneration. Cell 2010, 140:918-934. 10.1016/j.cell.2010.02.016, 2873093, 20303880.
    • (2010) Cell , vol.140 , pp. 918-934
    • Glass, C.K.1    Saijo, K.2    Winner, B.3    Marchetto, M.C.4    Gage, F.H.5
  • 37
    • 0036429923 scopus 로고    scopus 로고
    • Astrocytes enhance lipopolysaccharide-induced nitric oxide production by microglial cells
    • 10.1046/j.1460-9568.2002.02199.x, 12405988
    • Sola C, Casal C, Tusell JM, Serratosa J. Astrocytes enhance lipopolysaccharide-induced nitric oxide production by microglial cells. Eur J Neurosci 2002, 16:1275-1283. 10.1046/j.1460-9568.2002.02199.x, 12405988.
    • (2002) Eur J Neurosci , vol.16 , pp. 1275-1283
    • Sola, C.1    Casal, C.2    Tusell, J.M.3    Serratosa, J.4
  • 39
    • 37449023313 scopus 로고    scopus 로고
    • Microglial cells in astroglial cultures: a cautionary note
    • 10.1186/1742-2094-4-26, 2140055, 17937799
    • Saura J. Microglial cells in astroglial cultures: a cautionary note. J Neuroinflammation 2007, 4:26. 10.1186/1742-2094-4-26, 2140055, 17937799.
    • (2007) J Neuroinflammation , vol.4 , pp. 26
    • Saura, J.1
  • 40
    • 0030987656 scopus 로고    scopus 로고
    • An essential role for C/EBPbeta in female reproduction
    • 10.1101/gad.11.17.2153, 275394, 9303532
    • Sterneck E, Tessarollo L, Johnson PF. An essential role for C/EBPbeta in female reproduction. Genes Dev 1997, 11:2153-2162. 10.1101/gad.11.17.2153, 275394, 9303532.
    • (1997) Genes Dev , vol.11 , pp. 2153-2162
    • Sterneck, E.1    Tessarollo, L.2    Johnson, P.F.3
  • 41
    • 33747346235 scopus 로고    scopus 로고
    • Signal integration between IFNgamma and TLR signalling pathways in macrophages
    • 10.1016/j.imbio.2006.05.007, 16920490
    • Schroder K, Sweet MJ, Hume DA. Signal integration between IFNgamma and TLR signalling pathways in macrophages. Immunobiology 2006, 211:511-524. 10.1016/j.imbio.2006.05.007, 16920490.
    • (2006) Immunobiology , vol.211 , pp. 511-524
    • Schroder, K.1    Sweet, M.J.2    Hume, D.A.3
  • 42
    • 77949844439 scopus 로고    scopus 로고
    • C/EBP-beta regulates endoplasmic reticulum stress-triggered cell death in mouse and human models
    • 10.1371/journal.pone.0009516, 2831074, 20209087
    • Meir O, Dvash E, Werman A, Rubinstein M. C/EBP-beta regulates endoplasmic reticulum stress-triggered cell death in mouse and human models. PLoS One 2010, 5:e9516. 10.1371/journal.pone.0009516, 2831074, 20209087.
    • (2010) PLoS One , vol.5
    • Meir, O.1    Dvash, E.2    Werman, A.3    Rubinstein, M.4
  • 43
    • 41549153181 scopus 로고    scopus 로고
    • C/EBPs: recipients of extracellular signals through proteome modulation
    • 10.1016/j.ceb.2008.02.002, 18358708
    • Nerlov C. C/EBPs: recipients of extracellular signals through proteome modulation. Curr Opin Cell Biol 2008, 20:180-185. 10.1016/j.ceb.2008.02.002, 18358708.
    • (2008) Curr Opin Cell Biol , vol.20 , pp. 180-185
    • Nerlov, C.1
  • 44
    • 0031432620 scopus 로고    scopus 로고
    • Cross-talk between transcription factors NF-kappa B and C/EBP in the transcriptional regulation of genes
    • 10.1016/S1357-2725(97)00083-6, 9570146
    • Xia C, Cheshire JK, Patel H, Woo P. Cross-talk between transcription factors NF-kappa B and C/EBP in the transcriptional regulation of genes. Int J Biochem Cell Biol 1997, 29:1525-1539. 10.1016/S1357-2725(97)00083-6, 9570146.
    • (1997) Int J Biochem Cell Biol , vol.29 , pp. 1525-1539
    • Xia, C.1    Cheshire, J.K.2    Patel, H.3    Woo, P.4
  • 46
    • 79953873258 scopus 로고    scopus 로고
    • The CCAAT/enhancer binding protein (C/EBP) delta is differently regulated by fibrillar and oligomeric forms of the Alzheimer amyloid-beta peptide
    • 10.1186/1742-2094-8-34, 3096570, 21492414
    • Ramberg V, Tracy LM, Samuelsson M, Nilsson LN, Iverfeldt K. The CCAAT/enhancer binding protein (C/EBP) delta is differently regulated by fibrillar and oligomeric forms of the Alzheimer amyloid-beta peptide. J Neuroinflammation 2011, 8:34. 10.1186/1742-2094-8-34, 3096570, 21492414.
    • (2011) J Neuroinflammation , vol.8 , pp. 34
    • Ramberg, V.1    Tracy, L.M.2    Samuelsson, M.3    Nilsson, L.N.4    Iverfeldt, K.5
  • 47
    • 0037090244 scopus 로고    scopus 로고
    • C/EBP beta gene inactivation causes both impaired and enhanced gene expression and inverse regulation of IL-12 p40 and p35 mRNAs in macrophages
    • Gorgoni B, Maritano D, Marthyn P, Righi M, Poli V. C/EBP beta gene inactivation causes both impaired and enhanced gene expression and inverse regulation of IL-12 p40 and p35 mRNAs in macrophages. J Immunol 2002, 168:4055-4062.
    • (2002) J Immunol , vol.168 , pp. 4055-4062
    • Gorgoni, B.1    Maritano, D.2    Marthyn, P.3    Righi, M.4    Poli, V.5
  • 48
    • 0027161216 scopus 로고
    • Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide
    • Merrill JE, Ignarro LJ, Sherman MP, Melinek J, Lane TE. Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide. J Immunol 1993, 151:2132-2141.
    • (1993) J Immunol , vol.151 , pp. 2132-2141
    • Merrill, J.E.1    Ignarro, L.J.2    Sherman, M.P.3    Melinek, J.4    Lane, T.E.5
  • 49
    • 78650614116 scopus 로고    scopus 로고
    • IFN-gamma abrogates endotoxin tolerance by facilitating Toll-like receptor-induced chromatin remodeling
    • 10.1073/pnas.1007816107, 2984206, 20974955
    • Chen J, Ivashkiv LB. IFN-gamma abrogates endotoxin tolerance by facilitating Toll-like receptor-induced chromatin remodeling. Proc Natl Acad Sci USA 2010, 107:19438-19443. 10.1073/pnas.1007816107, 2984206, 20974955.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 19438-19443
    • Chen, J.1    Ivashkiv, L.B.2
  • 50
    • 0037450633 scopus 로고    scopus 로고
    • Recruitment of p300 by C/EBPbeta triggers phosphorylation of p300 and modulates coactivator activity
    • 10.1093/emboj/cdg076, 145436, 12574124
    • Schwartz C, Beck K, Mink S, Schmolke M, Budde B, Wenning D, Klempnauer KH. Recruitment of p300 by C/EBPbeta triggers phosphorylation of p300 and modulates coactivator activity. EMBO J 2003, 22:882-892. 10.1093/emboj/cdg076, 145436, 12574124.
    • (2003) EMBO J , vol.22 , pp. 882-892
    • Schwartz, C.1    Beck, K.2    Mink, S.3    Schmolke, M.4    Budde, B.5    Wenning, D.6    Klempnauer, K.H.7
  • 51
    • 45149089670 scopus 로고    scopus 로고
    • The Med1 subunit of transcriptional mediator plays a central role in regulating CCAAT/enhancer-binding protein-beta-driven transcription in response to interferon-gamma
    • 10.1074/jbc.M800604200, 2442347, 18339625
    • Li H, Gade P, Nallar SC, Raha A, Roy SK, Karra S, Reddy JK, Reddy SP, Kalvakolanu DV. The Med1 subunit of transcriptional mediator plays a central role in regulating CCAAT/enhancer-binding protein-beta-driven transcription in response to interferon-gamma. J Biol Chem 2008, 283:13077-13086. 10.1074/jbc.M800604200, 2442347, 18339625.
    • (2008) J Biol Chem , vol.283 , pp. 13077-13086
    • Li, H.1    Gade, P.2    Nallar, S.C.3    Raha, A.4    Roy, S.K.5    Karra, S.6    Reddy, J.K.7    Reddy, S.P.8    Kalvakolanu, D.V.9
  • 52
    • 35548986304 scopus 로고    scopus 로고
    • Microglia: active sensor and versatile effector cells in the normal and pathologic brain
    • 10.1038/nn1997, 17965659
    • Hanisch UK, Kettenmann H. Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat Neurosci 2007, 10:1387-1394. 10.1038/nn1997, 17965659.
    • (2007) Nat Neurosci , vol.10 , pp. 1387-1394
    • Hanisch, U.K.1    Kettenmann, H.2
  • 53
    • 33646583488 scopus 로고    scopus 로고
    • Nitric oxide-producing microglia mediate thrombin-induced degeneration of dopaminergic neurons in rat midbrain slice culture
    • 10.1111/j.1471-4159.2006.03752.x, 16638023
    • Katsuki H, Okawara M, Shibata H, Kume T, Akaike A. Nitric oxide-producing microglia mediate thrombin-induced degeneration of dopaminergic neurons in rat midbrain slice culture. J Neurochem 2006, 97:1232-1242. 10.1111/j.1471-4159.2006.03752.x, 16638023.
    • (2006) J Neurochem , vol.97 , pp. 1232-1242
    • Katsuki, H.1    Okawara, M.2    Shibata, H.3    Kume, T.4    Akaike, A.5
  • 54
    • 0036584232 scopus 로고    scopus 로고
    • Peroxynitrite mediates neurotoxicity of amyloid beta-peptide1-42- and lipopolysaccharide-activated microglia
    • Xie Z, Wei M, Morgan TE, Fabrizio P, Han D, Finch CE, Longo VD. Peroxynitrite mediates neurotoxicity of amyloid beta-peptide1-42- and lipopolysaccharide-activated microglia. J Neurosci 2002, 22:3484-3492.
    • (2002) J Neurosci , vol.22 , pp. 3484-3492
    • Xie, Z.1    Wei, M.2    Morgan, T.E.3    Fabrizio, P.4    Han, D.5    Finch, C.E.6    Longo, V.D.7
  • 56
    • 33947515418 scopus 로고    scopus 로고
    • Involvement of interferon-gamma in microglial-mediated loss of dopaminergic neurons
    • 10.1523/JNEUROSCI.5321-06.2007, 17376993
    • Mount MP, Lira A, Grimes D, Smith PD, Faucher S, Slack R, Anisman H, Hayley S, Park DS. Involvement of interferon-gamma in microglial-mediated loss of dopaminergic neurons. J Neurosci 2007, 27:3328-3337. 10.1523/JNEUROSCI.5321-06.2007, 17376993.
    • (2007) J Neurosci , vol.27 , pp. 3328-3337
    • Mount, M.P.1    Lira, A.2    Grimes, D.3    Smith, P.D.4    Faucher, S.5    Slack, R.6    Anisman, H.7    Hayley, S.8    Park, D.S.9
  • 58
    • 79952941281 scopus 로고    scopus 로고
    • Use of ibuprofen and risk of Parkinson disease
    • 10.1212/WNL.0b013e31820f2d79, 21368281
    • Gao X, Chen H, Schwarzschild MA, Ascherio A. Use of ibuprofen and risk of Parkinson disease. Neurology 2011, 76:863-869. 10.1212/WNL.0b013e31820f2d79, 21368281.
    • (2011) Neurology , vol.76 , pp. 863-869
    • Gao, X.1    Chen, H.2    Schwarzschild, M.A.3    Ascherio, A.4
  • 59
    • 0034994528 scopus 로고    scopus 로고
    • Antihypertensive drugs and incidence of dementia: the Rotterdam Study
    • 10.1016/S0197-4580(00)00241-4, 11378246
    • in't Veld BA, Ruitenberg A, Hofman A, Stricker BH, Breteler MM. Antihypertensive drugs and incidence of dementia: the Rotterdam Study. Neurobiol Aging 2001, 22:407-412. 10.1016/S0197-4580(00)00241-4, 11378246.
    • (2001) Neurobiol Aging , vol.22 , pp. 407-412
    • in't Veld, B.A.1    Ruitenberg, A.2    Hofman, A.3    Stricker, B.H.4    Breteler, M.M.5
  • 60
    • 0031775944 scopus 로고    scopus 로고
    • CCAAT/enhancer binding protein beta is a neuronal transcriptional regulator activated by nerve growth factor receptor signaling
    • Sterneck E, Johnson PF. CCAAT/enhancer binding protein beta is a neuronal transcriptional regulator activated by nerve growth factor receptor signaling. J Neurochem 1998, 70:2424-2433.
    • (1998) J Neurochem , vol.70 , pp. 2424-2433
    • Sterneck, E.1    Johnson, P.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.