Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: Implications for neuronal damage

Human Molecular Genetics

Volumn 20, Issue 13, 2011, Pages 2495-2509

  Manczak, Maria ^a   Calkins, Marcus J ^a   Reddy, P Hemachandra ^a,b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; DYNAMIN I; MESSENGER RNA; MITOCHONDRIAL PROTEIN; MITOFUSIN 1; MITOFUSIN 2; MONOMER; OLIGOMER; OPTIC ATROPHY 1 PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

AGED; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITIVE DEFECT; DISEASE COURSE; DISEASE SEVERITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FEMALE; FRONTAL CORTEX; GENE EXPRESSION; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; MALE; MOUSE; NERVE CELL LESION; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STRUCTURAL GENE; SYNAPSE; UPREGULATION;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CYCLOOXYGENASE 1; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION; GENES, MITOCHONDRIAL; GTP PHOSPHOHYDROLASES; HUMANS; MALE; MICE; MICE, TRANSGENIC; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NEURONS; PROTEIN BINDING; PROTEIN TRANSPORT; RNA, MESSENGER;

MUS MUSCULUS;

EID: 79958721260     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddr139     Document Type: Article

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