Alzheimer's disease: Early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci

Nature Neuroscience

Volumn 17, Issue 9, 2014, Pages 1156-1163

  De Jager, Philip L ^a,b,c   Srivastava, Gyan ^a,c   Lunnon, Katie ^d,e   Burgess, Jeremy ^f,g   Schalkwyk, Leonard C ^d,e   Yu, Lei ^h   Eaton, Matthew L ^c,i   Keenan, Brendan T ^a,c   Ernst, Jason ^c,i   McCabe, Cristin ^c   Tang, Anna ^a   Raj, Towfique ^a,b,c   Replogle, Joseph ^a,b,c   Brodeur, Wendy ^c   Gabriel, Stacey ^c   Chai, High S ^f,g   Younkin, Curtis ^f   Younkin, Steven G ^f   Zou, Fanggeng ^f   Szyf, Moshe ^j   Epstein, Charles B ^c   Schneider, Julie A ^h   Bernstein, Bradley E ^b,c,k   Meissner, Alex ^c,i,l   Ertekin Taner, Nilufer ^f,g   Chibnik, Lori B ^a,b,c   Kellis, Manolis ^c,i   Mill, Jonathan ^d,e   Bennett, David A ^h   more..

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d UNIVERSITY OF EXETER MEDICAL SCHOOL   (United Kingdom)

^e KING'S COLLEGE LONDON   (United Kingdom)

^f MAYO GRADUATE SCHOOL   (United States)

^g MAYO CLINIC   (United States)

^h RUSH UNIVERSITY MEDICAL CENTER   (United States)

ⁱ MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^j MCGILL UNIVERSITY   (Canada)

^k MASSACHUSETTS GENERAL HOSPITAL   (United States)

^l HARVARD STEM CELL INSTITUTE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; ANK1 GENE; ARTICLE; ASYMPTOMATIC DISEASE; AUTOPSY; BIN1 GENE; BRAIN REGION; CDH23 GENE; CLINICAL FEATURE; CPG ISLAND; DIP2A GENE; DISEASE PREDISPOSITION; DNA METHYLATION; GENE; GENE LOCUS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; HUMAN; HUMAN GENOME; HUMAN TISSUE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; RHBDF2 GENE; RPL13 GENE; SERPINF1 GENE; SERPINF2 GENE; VALIDATION STUDY; AGED; AMYLOIDOSIS; BRAIN; EPIDEMIOLOGY; FEMALE; GENETIC PREDISPOSITION; GENETICS; MALE; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY; PROTEIN PROTEIN INTERACTION; VERY ELDERLY;

ANK1 PROTEIN, HUMAN; ANKYRIN; BIN1 PROTEIN, HUMAN; CARRIER PROTEIN; NUCLEAR PROTEIN; RHBDF2 PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOIDOSIS; ANKYRINS; BRAIN; CARRIER PROTEINS; CPG ISLANDS; DNA METHYLATION; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MALE; MIDDLE AGED; NUCLEAR PROTEINS; PROTEIN INTERACTION MAPS; TUMOR SUPPRESSOR PROTEINS;

EID: 84919784465     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.3786     Document Type: Article

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