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Volumn 133, Issue 4, 2012, Pages 107-111

Stochastic modulations of the pace and patterns of ageing: Impacts on quasi-stochastic distributions of multiple geriatric pathologies

Author keywords

Epigenetic drift; Evolutionary biology; Geriatric pathology; Mitochondria; Somatic mutation; Stochastic events

Indexed keywords

NEUROTOXIN;

EID: 84860758536     PISSN: 00476374     EISSN: 18726216     Source Type: Journal    
DOI: 10.1016/j.mad.2011.09.001     Document Type: Article
Times cited : (30)

References (62)
  • 1
    • 0028334412 scopus 로고
    • Life span and cancer mortality in the beagle dog and humans
    • Albert R.E., Benjamin S.A., Shukla R. Life span and cancer mortality in the beagle dog and humans. Mech. Ageing Dev. 1994, 74:149-159.
    • (1994) Mech. Ageing Dev. , vol.74 , pp. 149-159
    • Albert, R.E.1    Benjamin, S.A.2    Shukla, R.3
  • 5
    • 78650171589 scopus 로고    scopus 로고
    • Towards a unifying theory of late stochastic effects of ionizing radiation
    • Baverstock K., Karotki A.V. Towards a unifying theory of late stochastic effects of ionizing radiation. Mutat. Res. 2011, 718:1-9.
    • (2011) Mutat. Res. , vol.718 , pp. 1-9
    • Baverstock, K.1    Karotki, A.V.2
  • 6
    • 0000874922 scopus 로고
    • Evidence for a monoclonal origin of human atherosclerotic plaques
    • Benditt E.P., Benditt J.M. Evidence for a monoclonal origin of human atherosclerotic plaques. Proc. Natl. Acad. Sci. U.S.A. 1973, 70:1753-1756.
    • (1973) Proc. Natl. Acad. Sci. U.S.A. , vol.70 , pp. 1753-1756
    • Benditt, E.P.1    Benditt, J.M.2
  • 8
    • 78650265812 scopus 로고    scopus 로고
    • DNA damage and cell cycle events implicate cerebellar dentate nucleus neurons as targets of Alzheimer's disease
    • Chen J., Cohen M.L., Lerner A.J., Yang Y., Herrup K. DNA damage and cell cycle events implicate cerebellar dentate nucleus neurons as targets of Alzheimer's disease. Mol. Neurodegener. 2010, 5:60.
    • (2010) Mol. Neurodegener. , vol.5 , pp. 60
    • Chen, J.1    Cohen, M.L.2    Lerner, A.J.3    Yang, Y.4    Herrup, K.5
  • 9
    • 77953724946 scopus 로고    scopus 로고
    • A highly sensitive peptide substrate for detecting two Ass-degrading enzymes: neprilysin and insulin-degrading enzyme
    • Chen P.T., Liao T.Y., Hu C.J., Wu S.T., Wang S.S., Chen R.P. A highly sensitive peptide substrate for detecting two Ass-degrading enzymes: neprilysin and insulin-degrading enzyme. J. Neurosci. Methods 2010, 190:57-62.
    • (2010) J. Neurosci. Methods , vol.190 , pp. 57-62
    • Chen, P.T.1    Liao, T.Y.2    Hu, C.J.3    Wu, S.T.4    Wang, S.S.5    Chen, R.P.6
  • 11
    • 0014279781 scopus 로고
    • Variation of atherosclerosis with age
    • Eggen D.A., Solberg L.A. Variation of atherosclerosis with age. Lab. Invest. 1968, 18:571-579.
    • (1968) Lab. Invest. , vol.18 , pp. 571-579
    • Eggen, D.A.1    Solberg, L.A.2
  • 14
    • 0024465870 scopus 로고
    • Mutator phenotype of Werner syndrome is characterized by extensive deletions
    • Fukuchi K., Martin G.M., Monnat R.J. Mutator phenotype of Werner syndrome is characterized by extensive deletions. Proc. Natl. Acad. Sci. U.S.A. 1989, 86:5893-5897.
    • (1989) Proc. Natl. Acad. Sci. U.S.A. , vol.86 , pp. 5893-5897
    • Fukuchi, K.1    Martin, G.M.2    Monnat, R.J.3
  • 15
    • 0013942563 scopus 로고
    • The moulding of senescence by natural selection
    • Hamilton W.D. The moulding of senescence by natural selection. J. Theor. Biol. 1966, 12:12-45.
    • (1966) J. Theor. Biol. , vol.12 , pp. 12-45
    • Hamilton, W.D.1
  • 16
    • 77957374539 scopus 로고    scopus 로고
    • Inheritance of epigenetic aberrations (constitutional epimutations) in cancer susceptibility
    • Hitchins M.P. Inheritance of epigenetic aberrations (constitutional epimutations) in cancer susceptibility. Adv. Genet. 2010, 70:201-243.
    • (2010) Adv. Genet. , vol.70 , pp. 201-243
    • Hitchins, M.P.1
  • 17
    • 0034123008 scopus 로고    scopus 로고
    • Broadly altered expression of the mRNA isoforms of FE65, a facilitator of beta amyloidogenesis, in Alzheimer cerebellum and other brain regions
    • Hu Q., Jin L.W., Starbuck M.Y., Martin G.M. Broadly altered expression of the mRNA isoforms of FE65, a facilitator of beta amyloidogenesis, in Alzheimer cerebellum and other brain regions. J. Neurosci. Res. 2000, 60:73-86.
    • (2000) J. Neurosci. Res. , vol.60 , pp. 73-86
    • Hu, Q.1    Jin, L.W.2    Starbuck, M.Y.3    Martin, G.M.4
  • 18
    • 33646482116 scopus 로고    scopus 로고
    • Investigations in generalized osteoarthritis. Part 2: special histological features in generalized osteoarthritis (histological investigations in Heberden's nodes using a histological score)
    • Irlenbusch U., Dominick G. Investigations in generalized osteoarthritis. Part 2: special histological features in generalized osteoarthritis (histological investigations in Heberden's nodes using a histological score). Osteoarthr. Cartilage 2006, 14:428-434.
    • (2006) Osteoarthr. Cartilage , vol.14 , pp. 428-434
    • Irlenbusch, U.1    Dominick, G.2
  • 19
    • 0142185046 scopus 로고    scopus 로고
    • Age-related epigenetic changes and the immune system
    • Issa J.P. Age-related epigenetic changes and the immune system. Clin. Immunol. 2003, 109:103-108.
    • (2003) Clin. Immunol. , vol.109 , pp. 103-108
    • Issa, J.P.1
  • 21
    • 0029976873 scopus 로고    scopus 로고
    • Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesis
    • Issa J.P., Vertino P.M., Boehm C.D., Newsham I.F., Baylin S.B. Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesis. Proc. Natl. Acad. Sci. U.S.A. 1996, 93:11757-11762.
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 11757-11762
    • Issa, J.P.1    Vertino, P.M.2    Boehm, C.D.3    Newsham, I.F.4    Baylin, S.B.5
  • 22
    • 84987485476 scopus 로고
    • Possible epigenetic mechanisms of tumor progression: induction of high-frequency heritable but phenotypically unstable changes in the tumorigenic and metastatic properties of tumor cell populations by 5-azacytidine treatment
    • Kerbel R.S., Frost P., Liteplo R., Carlow D.A., Elliott B.E. Possible epigenetic mechanisms of tumor progression: induction of high-frequency heritable but phenotypically unstable changes in the tumorigenic and metastatic properties of tumor cell populations by 5-azacytidine treatment. J. Cell. Physiol. Suppl. 1984, 3:87-97.
    • (1984) J. Cell. Physiol. Suppl. , vol.3 , pp. 87-97
    • Kerbel, R.S.1    Frost, P.2    Liteplo, R.3    Carlow, D.A.4    Elliott, B.E.5
  • 24
    • 0016669094 scopus 로고
    • Evolution at two levels in humans and chimpanzees
    • King M.C., Wilson A.C. Evolution at two levels in humans and chimpanzees. Science 1975, 188:107-116.
    • (1975) Science , vol.188 , pp. 107-116
    • King, M.C.1    Wilson, A.C.2
  • 26
    • 18744401335 scopus 로고    scopus 로고
    • Portraits of science. A Polish, Jewish scientist in 19th-century Prussia
    • Lagunoff D. Portraits of science. A Polish, Jewish scientist in 19th-century Prussia. Science 2002, 298:2331.
    • (2002) Science , vol.298 , pp. 2331
    • Lagunoff, D.1
  • 27
    • 76249097841 scopus 로고    scopus 로고
    • Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening
    • Liao C.Y., Rikke B.A., Johnson T.E., Diaz V., Nelson J.F. Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening. Aging Cell 2010, 9:92-95.
    • (2010) Aging Cell , vol.9 , pp. 92-95
    • Liao, C.Y.1    Rikke, B.A.2    Johnson, T.E.3    Diaz, V.4    Nelson, J.F.5
  • 28
    • 79955663580 scopus 로고    scopus 로고
    • Regulated intramembrane proteolysis - Lessons from amyloid precursor protein processing
    • Lichtenthaler S.F., Haass C., Steiner H. Regulated intramembrane proteolysis - Lessons from amyloid precursor protein processing. J. Neurochem. 2011.
    • (2011) J. Neurochem.
    • Lichtenthaler, S.F.1    Haass, C.2    Steiner, H.3
  • 29
    • 78649471907 scopus 로고    scopus 로고
    • Mutator phenotype in cancer: origin and consequences
    • Loeb L.A. Mutator phenotype in cancer: origin and consequences. Semin. Cancer Biol. 2010, 20:279-280.
    • (2010) Semin. Cancer Biol. , vol.20 , pp. 279-280
    • Loeb, L.A.1
  • 30
    • 0016176530 scopus 로고
    • Errors in DNA replication as a basis of malignant changes
    • Loeb L.A., Springgate C.F., Battula N. Errors in DNA replication as a basis of malignant changes. Cancer Res. 1974, 34:2311-2321.
    • (1974) Cancer Res. , vol.34 , pp. 2311-2321
    • Loeb, L.A.1    Springgate, C.F.2    Battula, N.3
  • 31
    • 63849115094 scopus 로고    scopus 로고
    • Insights into the pathogenesis and pathogenicity of cerebral amyloid angiopathy
    • Love S., Miners S., Palmer J., Chalmers K., Kehoe P. Insights into the pathogenesis and pathogenicity of cerebral amyloid angiopathy. Front. Biosci. 2009, 14:4778-4792.
    • (2009) Front. Biosci. , vol.14 , pp. 4778-4792
    • Love, S.1    Miners, S.2    Palmer, J.3    Chalmers, K.4    Kehoe, P.5
  • 32
    • 0017840139 scopus 로고
    • Genetic syndromes in man with potential relevance to the pathobiology of aging
    • Martin G.M. Genetic syndromes in man with potential relevance to the pathobiology of aging. Birth Defects Orig. Artic. Ser. 1978, 14:5-39.
    • (1978) Birth Defects Orig. Artic. Ser. , vol.14 , pp. 5-39
    • Martin, G.M.1
  • 33
    • 0018381797 scopus 로고
    • Proliferative homeostasis and its age-related aberrations
    • Martin G.M. Proliferative homeostasis and its age-related aberrations. Mech. Ageing Dev. 1979, 9:385-391.
    • (1979) Mech. Ageing Dev. , vol.9 , pp. 385-391
    • Martin, G.M.1
  • 34
    • 0030070430 scopus 로고    scopus 로고
    • Somatic mutagenesis and antimutagenesis in aging research
    • Martin G.M. Somatic mutagenesis and antimutagenesis in aging research. Mutat. Res. 1996, 350:35-41.
    • (1996) Mutat. Res. , vol.350 , pp. 35-41
    • Martin, G.M.1
  • 35
    • 23044446596 scopus 로고    scopus 로고
    • Epigenetic drift in aging identical twins
    • Martin G.M. Epigenetic drift in aging identical twins. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:10413-10414.
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 10413-10414
    • Martin, G.M.1
  • 36
    • 13944280713 scopus 로고    scopus 로고
    • Genetic modulation of senescent phenotypes in Homo sapiens
    • Martin G.M. Genetic modulation of senescent phenotypes in Homo sapiens. Cell 2005, 120:523-532.
    • (2005) Cell , vol.120 , pp. 523-532
    • Martin, G.M.1
  • 37
    • 33846119369 scopus 로고    scopus 로고
    • The genetics and epigenetics of altered proliferative homeostasis in ageing and cancer
    • Martin G.M. The genetics and epigenetics of altered proliferative homeostasis in ageing and cancer. Mech. Ageing Dev. 2007, 128:9-12.
    • (2007) Mech. Ageing Dev. , vol.128 , pp. 9-12
    • Martin, G.M.1
  • 38
    • 74049087181 scopus 로고    scopus 로고
    • Epigenetic gambling and epigenetic drift as an antagonistic pleiotropic mechanism of aging
    • Martin G.M. Epigenetic gambling and epigenetic drift as an antagonistic pleiotropic mechanism of aging. Aging Cell 2009, 8:761-764.
    • (2009) Aging Cell , vol.8 , pp. 761-764
    • Martin, G.M.1
  • 39
    • 0033636673 scopus 로고    scopus 로고
    • Transcriptional infidelity in aging cells and its relevance for the Orgel hypothesis
    • discussion 903-894
    • Martin G.M., Bressler S.L. Transcriptional infidelity in aging cells and its relevance for the Orgel hypothesis. Neurobiol. Aging 2000, 21:897-900. discussion 903-894.
    • (2000) Neurobiol. Aging , vol.21 , pp. 897-900
    • Martin, G.M.1    Bressler, S.L.2
  • 40
    • 0015966119 scopus 로고
    • Clonal selection, attenuation and differentiation in an in vitro model of hyperplasia
    • Martin G.M., Sprague C.A., Norwood T.H., Pendergrass W.R. Clonal selection, attenuation and differentiation in an in vitro model of hyperplasia. Am. J. Pathol. 1974, 74:137-154.
    • (1974) Am. J. Pathol. , vol.74 , pp. 137-154
    • Martin, G.M.1    Sprague, C.A.2    Norwood, T.H.3    Pendergrass, W.R.4
  • 41
    • 73649150958 scopus 로고
    • The maintenance of the accuracy of protein synthesis and its relevance to ageing
    • Orgel L.E. The maintenance of the accuracy of protein synthesis and its relevance to ageing. Proc. Natl. Acad. Sci. U.S.A. 1963, 49:517-521.
    • (1963) Proc. Natl. Acad. Sci. U.S.A. , vol.49 , pp. 517-521
    • Orgel, L.E.1
  • 42
    • 0014877876 scopus 로고
    • The maintenance of the accuracy of protein synthesis and its relevance to ageing: a correction
    • Orgel L.E. The maintenance of the accuracy of protein synthesis and its relevance to ageing: a correction. Proc. Natl. Acad. Sci. U.S.A. 1970, 67:1476.
    • (1970) Proc. Natl. Acad. Sci. U.S.A. , vol.67 , pp. 1476
    • Orgel, L.E.1
  • 43
    • 77956376257 scopus 로고    scopus 로고
    • Mitochondrial theory of aging in human age-related sarcopenia
    • Parise G., De Lisio M. Mitochondrial theory of aging in human age-related sarcopenia. Interdiscip. Top Gerontol. 2010, 37:142-156.
    • (2010) Interdiscip. Top Gerontol. , vol.37 , pp. 142-156
    • Parise, G.1    De Lisio, M.2
  • 44
    • 67649233695 scopus 로고    scopus 로고
    • What makes us human?
    • Pollard K.S. What makes us human?. Sci. Am. 2009, 300:44-49.
    • (2009) Sci. Am. , vol.300 , pp. 44-49
    • Pollard, K.S.1
  • 47
    • 77954587784 scopus 로고    scopus 로고
    • Atheromas feel the pressure: biomechanical stress and atherosclerosis
    • Pyle A.L., Young P.P. Atheromas feel the pressure: biomechanical stress and atherosclerosis. Am. J. Pathol. 2010, 177:4-9.
    • (2010) Am. J. Pathol. , vol.177 , pp. 4-9
    • Pyle, A.L.1    Young, P.P.2
  • 48
    • 0034105760 scopus 로고    scopus 로고
    • Mitochondrial respiratory chain activity in idiopathic dilated cardiomyopathy
    • Quigley A.F., Kapsa R.M., Esmore D., Hale G., Byrne E. Mitochondrial respiratory chain activity in idiopathic dilated cardiomyopathy. J. Card. Fail. 2000, 6:47-55.
    • (2000) J. Card. Fail. , vol.6 , pp. 47-55
    • Quigley, A.F.1    Kapsa, R.M.2    Esmore, D.3    Hale, G.4    Byrne, E.5
  • 49
    • 0020436487 scopus 로고
    • Encephalomyocarditis virus as a probe of errors in macromolecular synthesis in aging mice
    • Rabinovitch P.S., Martin G.M. Encephalomyocarditis virus as a probe of errors in macromolecular synthesis in aging mice. Mech. Ageing Dev. 1982, 20:155-163.
    • (1982) Mech. Ageing Dev. , vol.20 , pp. 155-163
    • Rabinovitch, P.S.1    Martin, G.M.2
  • 50
    • 23044445756 scopus 로고    scopus 로고
    • A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans
    • Rea S.L., Wu D., Cypser J.R., Vaupel J.W., Johnson T.E. A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans. Nat. Genet. 2005, 37:894-898.
    • (2005) Nat. Genet. , vol.37 , pp. 894-898
    • Rea, S.L.1    Wu, D.2    Cypser, J.R.3    Vaupel, J.W.4    Johnson, T.E.5
  • 55
    • 79251554354 scopus 로고    scopus 로고
    • Selective vulnerability of neurons in layer II of the entorhinal cortex during aging and Alzheimer's disease
    • Stranahan A.M., Mattson M.P. Selective vulnerability of neurons in layer II of the entorhinal cortex during aging and Alzheimer's disease. Neural. Plast. 2010, 2010:108190.
    • (2010) Neural. Plast. , vol.2010 , pp. 108190
    • Stranahan, A.M.1    Mattson, M.P.2
  • 56
    • 84858676837 scopus 로고    scopus 로고
    • Does mitochondrial DNA play a role in Parkinson's disease? A review of cybrid and other supportive evidence
    • Swerdlow R.H. Does mitochondrial DNA play a role in Parkinson's disease? A review of cybrid and other supportive evidence. Antioxid. Redox Signal. 2011.
    • (2011) Antioxid. Redox Signal.
    • Swerdlow, R.H.1
  • 57
    • 78751662442 scopus 로고    scopus 로고
    • The role of G protein-coupled receptors in the pathology of Alzheimer's disease
    • Thathiah A., De Strooper B. The role of G protein-coupled receptors in the pathology of Alzheimer's disease. Nat. Rev. Neurosci. 2011, 12:73-87.
    • (2011) Nat. Rev. Neurosci. , vol.12 , pp. 73-87
    • Thathiah, A.1    De Strooper, B.2
  • 59
    • 0035127889 scopus 로고    scopus 로고
    • Mitochondrial DNA deletion mutations colocalize with segmental electron transport system abnormalities, muscle fiber atrophy, fiber splitting, and oxidative damage in sarcopenia
    • Wanagat J., Cao Z., Pathare P., Aiken J.M. Mitochondrial DNA deletion mutations colocalize with segmental electron transport system abnormalities, muscle fiber atrophy, fiber splitting, and oxidative damage in sarcopenia. FASEB J. 2001, 15:322-332.
    • (2001) FASEB J. , vol.15 , pp. 322-332
    • Wanagat, J.1    Cao, Z.2    Pathare, P.3    Aiken, J.M.4
  • 60
    • 0000055057 scopus 로고
    • Pleiotropy: natural-selection, and the evolution of senescence
    • Williams G.C. Pleiotropy: natural-selection, and the evolution of senescence. Evolution 1957, 11:398-411.
    • (1957) Evolution , vol.11 , pp. 398-411
    • Williams, G.C.1
  • 61
    • 76449107634 scopus 로고    scopus 로고
    • Monocytes in atherosclerosis: subsets and functions
    • Woollard K.J., Geissmann F. Monocytes in atherosclerosis: subsets and functions. Nat. Rev. Cardiol. 2010, 7:77-86.
    • (2010) Nat. Rev. Cardiol. , vol.7 , pp. 77-86
    • Woollard, K.J.1    Geissmann, F.2


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