Tau Promotes Neurodegeneration via DRP1 Mislocalization In Vivo

Neuron

Volumn 75, Issue 4, 2012, Pages 618-632

  DuBoff, Brian ^a   Götz, Jürgen ^b   Feany, Mel B ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CELL PROTEIN; MESSENGER RNA; MYOSIN; PROTEIN DRP1; TAU PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CYCLE ARREST; CELL DEATH; CELL ELONGATION; CELL ENERGY; CELL FUSION; CONTROLLED STUDY; DOWN REGULATION; DRP1 GENE; EMBRYO; GENE; GENE EXPRESSION REGULATION; IN VIVO STUDY; MITOCHONDRIAL MEMBRANE; MOLECULAR PATHOLOGY; MOUSE; NERVE CELL CULTURE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; TAUOPATHY;

ACTINS; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; ATP SYNTHETASE COMPLEXES; CELL CYCLE PROTEINS; CELL DEATH; CYTOPLASM; CYTOSKELETAL PROTEINS; DISEASE MODELS, ANIMAL; DROSOPHILA; DROSOPHILA PROTEINS; GELSOLIN; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEINS; HUMANS; IN SITU NICK-END LABELING; MICE; MICRORNAS; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MUTATION; MYOSINS; NERVE DEGENERATION; NEURONS; RNA INTERFERENCE; TAU PROTEINS; TAUOPATHIES; VOLTAGE-DEPENDENT ANION CHANNELS;

EID: 84865352799     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2012.06.026     Document Type: Article

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