Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology

Journal of Clinical Investigation

Volumn 114, Issue 1, 2004, Pages 121-130

  Rissman, Robert A ^a   Poon, Wayne W ^a   Blurton Jones, Mathew ^a   Oddo, Salvatore ^a   Torp, Reidun ^a   Vitek, Michael P ^b   LaFerla, Frank M ^a   Rohn, Troy T ^c   Cotman, Carl W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c BOISE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; CASPASE; CYTOSKELETON PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; TAU PROTEIN; MEMBRANE PROTEIN; PRESENILIN 1; PSEN1 PROTEIN, HUMAN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LOSS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMMUNOGOLD ELECTRON MICROSCOPY; LIGHT SCATTERING; MOUSE; NEUROFIBRILLARY TANGLE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; TRANSGENIC MOUSE; WESTERN BLOTTING; ANIMAL; ENZYMOLOGY; GENETICS; METABOLISM; MOUSE MUTANT; PATHOLOGY; PHOSPHORYLATION; PYRAMIDAL NERVE CELL; REFERENCE VALUE;

ALZHEIMER DISEASE; ANIMALS; CASPASES; HUMANS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; NEUROFIBRILLARY TANGLES; PHOSPHORYLATION; PRESENILIN-1; PYRAMIDAL CELLS; REFERENCE VALUES; TAU PROTEINS;

EID: 3242749074     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200420640     Document Type: Article

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