Consistent decrease in global DNA methylation and hydroxymethylation in the hippocampus of Alzheimer's disease patients

Neurobiology of Aging

Volumn 34, Issue 9, 2013, Pages 2091-2099

  Chouliaras, Leonidas ^a   Mastroeni, Diego ^a,b   Delvaux, Elaine ^b   Grover, Andrew ^b   Kenis, Gunter ^a   Hof, Patrick R ^c   Steinbusch, Harry W M ^a   Coleman, Paul D ^b   Rutten, Bart P F ^a   van den Hove, Daniel L A ^a,d,e  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b SUN HEALTH RESEARCH INSTITUTE   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF WÜRZBURG   (Germany)

^e NONE   (Netherlands)

Author keywords

Alzheimer's disease; Amyloid; DNA hydroxymethylation; DNA methylation; Epigenetics

Indexed keywords

5 HYDROXYMETHYLCYTIDINE; 5 METHYLCYTIDINE; CYTIDINE DERIVATIVE; UNCLASSIFIED DRUG;

AGED; ALZHEIMER DISEASE; AMYLOID PLAQUE; ARTICLE; BRAIN REGION; CLINICAL ARTICLE; CONTROLLED STUDY; DENTATE GYRUS; DNA METHYLATION; ENTORHINAL CORTEX; EPIGENETICS; FEMALE; GENETIC MARKER; GLIA CELL; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA3 REGION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MONOZYGOTIC TWINS; NEUROFIBRILLARY TANGLE; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; TISSUE HOMOGENATE;

AGED; AGED, 80 AND OVER; AGING; ALZHEIMER DISEASE; CYTIDINE; DEOXYCYTIDINE; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HIPPOCAMPUS; HUMANS; HYDROXYLATION; MALE;

EID: 84878944565     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2013.02.021     Document Type: Article

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