Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1α

Biochemical Journal

Volumn 416, Issue 3, 2008, Pages 387-394

  Pollard, Patrick J ^a   Loenarz, Christoph ^b   Mole, David R ^a   McDonough, Michael A ^b   Gleadle, Jonathan M ^c   Schofield, Christopher J ^b   Ratcliffe, Peter J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c FLINDERS MEDICAL CENTRE   (Australia)

Author keywords

Histone demethylase; Hypoxia; Hypoxia inducible factor 1 (HIF 1); Jumonji domain; Promoter; Transcription factor

Indexed keywords

HISTONE DEMETHYLASE; HYPOXIA; HYPOXIA-INDUCIBLE FACTOR 1 (HIF-1); JUMONJI DOMAIN; PROMOTER;

CELL CULTURE; GENES; TRANSCRIPTION FACTORS;

TRANSCRIPTION;

2 OXOGLUTARIC ACID; FERROUS ION; HISTONE DEMETHYLASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; JUMONJI DOMAIN CONTAINING 1A PROTEIN; JUMONJI DOMAIN CONTAINING 2B PROTEIN; JUMONJI DOMAIN CONTAINING 2C PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG; ALPHA-KETOGLUTARIC ACID; DEFEROXAMINE; DICARBOXYLIC AMINO ACID; JMJD1A PROTEIN, HUMAN; JMJD2B PROTEIN, HUMAN; JMJD2C PROTEIN, HUMAN; N DEMETHYLASE; OXALYLGLYCINE; OXYGENASE; PROTEIN SUBUNIT; SIDEROPHORE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TUMOR PROTEIN;

ARTICLE; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME SUBUNIT; FUNCTIONAL GENOMICS; GENE EXPRESSION REGULATION; GENE FUNCTION; GENETIC REGULATION; HUMAN; HUMAN CELL; HYPOXIA; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN METHYLATION; UPREGULATION; ANOXIA; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; MOLECULAR GENETICS; PROMOTER REGION;

AMINO ACIDS, DICARBOXYLIC; ANOXIA; CELL LINE; DEFEROXAMINE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; KETOGLUTARIC ACIDS; MOLECULAR SEQUENCE DATA; NEOPLASM PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDOREDUCTASES, N-DEMETHYLATING; OXYGENASES; PROMOTER REGIONS, GENETIC; PROTEIN SUBUNITS; RNA, SMALL INTERFERING; SIDEROPHORES; TRANSCRIPTION FACTORS;

EID: 58949097017     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20081238     Document Type: Article

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