-
1
-
-
0014618774
-
Tricarballylate and hydroxycitrate: substrate and inhibitor of ATP:citrate oxaloacetate lyase
-
Watson J.A., Fang M., Lowenstein J.M. Tricarballylate and hydroxycitrate: substrate and inhibitor of ATP:citrate oxaloacetate lyase. Arch. Biochem. Biophys. 1969, 135:209-217.
-
(1969)
Arch. Biochem. Biophys.
, vol.135
, pp. 209-217
-
-
Watson, J.A.1
Fang, M.2
Lowenstein, J.M.3
-
2
-
-
77956851379
-
Deficiency in hepatic ATP-citrate lyase affects VLDL-triglyceride mobilization and liver fatty acid composition in mice
-
Wang Q., Li S., Jiang L., Zhou Y., Li Z., Shao M., Li W., Liu Y. Deficiency in hepatic ATP-citrate lyase affects VLDL-triglyceride mobilization and liver fatty acid composition in mice. J. Lipid Res. 2010, 51:2516-2526.
-
(2010)
J. Lipid Res.
, vol.51
, pp. 2516-2526
-
-
Wang, Q.1
Li, S.2
Jiang, L.3
Zhou, Y.4
Li, Z.5
Shao, M.6
Li, W.7
Liu, Y.8
-
3
-
-
77957795415
-
ATP-citrate lyase reduction mediates palmitate-induced apoptosis in pancreatic beta cells
-
Chu K.Y., Lin Y., Hendel A., Kulpa J.E., Brownsey R.W., Johnson J.D. ATP-citrate lyase reduction mediates palmitate-induced apoptosis in pancreatic beta cells. J. Biol. Chem. 2010, 285:32606-32615.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 32606-32615
-
-
Chu, K.Y.1
Lin, Y.2
Hendel, A.3
Kulpa, J.E.4
Brownsey, R.W.5
Johnson, J.D.6
-
4
-
-
0026758929
-
Effects of nutrients and hormones on gene expression of ATP citrate-lyase in rat liver
-
Fukuda H., Katsurada A., Iritani N. Effects of nutrients and hormones on gene expression of ATP citrate-lyase in rat liver. Eur. J. Biochem. 1992, 209:217-222.
-
(1992)
Eur. J. Biochem.
, vol.209
, pp. 217-222
-
-
Fukuda, H.1
Katsurada, A.2
Iritani, N.3
-
5
-
-
35648954584
-
Feasibility of pathways for transfer of acyl groups from mitochondria to the cytosol to form short chain acyl-CoAs in the pancreatic beta cell
-
MacDonald M.J., Smith A.D., Hasan N.M., Sabat G., Fahien L.A. Feasibility of pathways for transfer of acyl groups from mitochondria to the cytosol to form short chain acyl-CoAs in the pancreatic beta cell. J. Biol. Chem. 2007, 282:30596-30606.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 30596-30606
-
-
MacDonald, M.J.1
Smith, A.D.2
Hasan, N.M.3
Sabat, G.4
Fahien, L.A.5
-
6
-
-
0021690458
-
Binding of ATP citrate lyase to the microsomal fraction of rat liver
-
Linn T.C., Srere P.A. Binding of ATP citrate lyase to the microsomal fraction of rat liver. J. Biol. Chem. 1984, 259:13379-13384.
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 13379-13384
-
-
Linn, T.C.1
Srere, P.A.2
-
7
-
-
66249105703
-
ATP-citrate lyase links cellular metabolism to histone acetylation
-
Wellen K.E., Hatzivassiliou G., Sachdeva U.M., Bui T.V., Cross J.R., Thompson C.B. ATP-citrate lyase links cellular metabolism to histone acetylation. Science 2009, 324:1076-1080.
-
(2009)
Science
, vol.324
, pp. 1076-1080
-
-
Wellen, K.E.1
Hatzivassiliou, G.2
Sachdeva, U.M.3
Bui, T.V.4
Cross, J.R.5
Thompson, C.B.6
-
9
-
-
0017138570
-
Structure of ATP citrate lyase from rat liver. Physicochemical studies and proteolytic modification
-
Singh M., Richards E.G., Mukherjee A., Srere P.A. Structure of ATP citrate lyase from rat liver. Physicochemical studies and proteolytic modification. J. Biol. Chem. 1976, 251:5242-5250.
-
(1976)
J. Biol. Chem.
, vol.251
, pp. 5242-5250
-
-
Singh, M.1
Richards, E.G.2
Mukherjee, A.3
Srere, P.A.4
-
10
-
-
0025058095
-
Rat ATP citrate-lyase. Molecular cloning and sequence analysis of a full-length cDNA and mRNA abundance as a function of diet, organ, and age
-
Elshourbagy N.A., Near J.C., Kmetz P.J., Sathe G.M., Southan C., Strickler J.E., Gross M., Young J.F., Wells T.N., Groot P.H. Rat ATP citrate-lyase. Molecular cloning and sequence analysis of a full-length cDNA and mRNA abundance as a function of diet, organ, and age. J. Biol. Chem. 1990, 265:1430-1435.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 1430-1435
-
-
Elshourbagy, N.A.1
Near, J.C.2
Kmetz, P.J.3
Sathe, G.M.4
Southan, C.5
Strickler, J.E.6
Gross, M.7
Young, J.F.8
Wells, T.N.9
Groot, P.H.10
-
11
-
-
77956244445
-
Identification of the citrate-binding site of human ATP-citrate lyase using X-ray crystallography
-
Sun T., Hayakawa K., Bateman K.S., Fraser M.E. Identification of the citrate-binding site of human ATP-citrate lyase using X-ray crystallography. J. Biol. Chem. 2010, 285:27418-27428.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 27418-27428
-
-
Sun, T.1
Hayakawa, K.2
Bateman, K.S.3
Fraser, M.E.4
-
12
-
-
80955125901
-
ADP-Mg2+ bound to the ATP-grasp domain of ATP-citrate lyase Acta Crystallogr
-
Sun T., Hayakawa K., Fraser M.E. ADP-Mg2+ bound to the ATP-grasp domain of ATP-citrate lyase Acta Crystallogr. Sect. F: Struct. Biol. Cryst. Commun. 2011, 67:1168-1172.
-
(2011)
Sect. F: Struct. Biol. Cryst. Commun.
, vol.67
, pp. 1168-1172
-
-
Sun, T.1
Hayakawa, K.2
Fraser, M.E.3
-
13
-
-
0018786278
-
Identification of ATP citrate lyase as a phosphoprotein
-
Linn T.C., Srere P.A. Identification of ATP citrate lyase as a phosphoprotein. J. Biol. Chem. 1979, 254:1691-1698.
-
(1979)
J. Biol. Chem.
, vol.254
, pp. 1691-1698
-
-
Linn, T.C.1
Srere, P.A.2
-
14
-
-
26644441651
-
ATP citrate lyase inhibition can suppress tumor cell growth
-
Hatzivassiliou G., Zhao F., Bauer D.E., Andreadis C., Shaw A.N., Dhanak D., Hingorani S.R., Tuveson D.A., Thompson C.B. ATP citrate lyase inhibition can suppress tumor cell growth. Cancer Cell 2005, 8:311-321.
-
(2005)
Cancer Cell
, vol.8
, pp. 311-321
-
-
Hatzivassiliou, G.1
Zhao, F.2
Bauer, D.E.3
Andreadis, C.4
Shaw, A.N.5
Dhanak, D.6
Hingorani, S.R.7
Tuveson, D.A.8
Thompson, C.B.9
-
15
-
-
0000203136
-
The citrate cleavage enzyme. I. Distribution and purification
-
Srere P.A. The citrate cleavage enzyme. I. Distribution and purification. J. Biol. Chem. 1959, 234:2544-2547.
-
(1959)
J. Biol. Chem.
, vol.234
, pp. 2544-2547
-
-
Srere, P.A.1
-
16
-
-
70350417307
-
A novel direct homogeneous assay for ATP citrate lyase
-
Ma Z., Chu C.H., Cheng D. A novel direct homogeneous assay for ATP citrate lyase. J. Lipid Res. 2009, 50:2131-2135.
-
(2009)
J. Lipid Res.
, vol.50
, pp. 2131-2135
-
-
Ma, Z.1
Chu, C.H.2
Cheng, D.3
-
17
-
-
80051914543
-
The lipogenesis pathway as a cancer target
-
Abramson H.N. The lipogenesis pathway as a cancer target. J. Med. Chem. 2011, 54:5615-5638.
-
(2011)
J. Med. Chem.
, vol.54
, pp. 5615-5638
-
-
Abramson, H.N.1
-
18
-
-
30544433533
-
ATP citrate lyase is an important component of cell growth and transformation
-
Bauer D.E., Hatzivassiliou G., Zhao F., Andreadis C., Thompson C.B. ATP citrate lyase is an important component of cell growth and transformation. Oncogene 2005, 24:6314-6322.
-
(2005)
Oncogene
, vol.24
, pp. 6314-6322
-
-
Bauer, D.E.1
Hatzivassiliou, G.2
Zhao, F.3
Andreadis, C.4
Thompson, C.B.5
-
19
-
-
0034725048
-
Transcriptional regulation of the ATP citrate-lyase gene by sterol regulatory element-binding proteins
-
Sato R., Okamoto A., Inoue J., Miyamoto W., Sakai Y., Emoto N., Shimano H., Maeda M. Transcriptional regulation of the ATP citrate-lyase gene by sterol regulatory element-binding proteins. J. Biol. Chem. 2000, 275:12497-12502.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 12497-12502
-
-
Sato, R.1
Okamoto, A.2
Inoue, J.3
Miyamoto, W.4
Sakai, Y.5
Emoto, N.6
Shimano, H.7
Maeda, M.8
-
20
-
-
54249161009
-
ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer
-
Migita T., Narita T., Nomura K., Miyagi E., Inazuka F., Matsuura M., Ushijima M., Mashima T., Seimiya H., Satoh Y., Okumura S., Nakagawa K., Ishikawa Y. ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer. Cancer Res. 2008, 68:8547-8554.
-
(2008)
Cancer Res.
, vol.68
, pp. 8547-8554
-
-
Migita, T.1
Narita, T.2
Nomura, K.3
Miyagi, E.4
Inazuka, F.5
Matsuura, M.6
Ushijima, M.7
Mashima, T.8
Seimiya, H.9
Satoh, Y.10
Okumura, S.11
Nakagawa, K.12
Ishikawa, Y.13
-
21
-
-
0031076275
-
Variant cDNA sequences of human ATP:citrate lyase: cloning, expression, and purification from baculovirus-infected insect cells
-
Lord K.A., Wang X.M., Simmons S.J., Bruckner R.C., Loscig J., O'Connor B., Bentley R., Smallwood A., Chadwick C.C., Stevis P.E., Ciccarelli R.B. Variant cDNA sequences of human ATP:citrate lyase: cloning, expression, and purification from baculovirus-infected insect cells. Protein Expr. Purif. 1997, 9:133-141.
-
(1997)
Protein Expr. Purif.
, vol.9
, pp. 133-141
-
-
Lord, K.A.1
Wang, X.M.2
Simmons, S.J.3
Bruckner, R.C.4
Loscig, J.5
O'Connor, B.6
Bentley, R.7
Smallwood, A.8
Chadwick, C.C.9
Stevis, P.E.10
Ciccarelli, R.B.11
-
22
-
-
0029101744
-
Phosphorylation of ATP-citrate lyase by nucleoside diphosphate kinase
-
Wagner P.D., Vu N.D. Phosphorylation of ATP-citrate lyase by nucleoside diphosphate kinase. J. Biol. Chem. 1995, 270:21758-21764.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 21758-21764
-
-
Wagner, P.D.1
Vu, N.D.2
-
23
-
-
0019813025
-
ATP-citrate lyase. Structure of a tryptic peptide containing the phosphorylation site directed by glucagon and the cAMP-dependent protein kinase
-
Pierce M.W., Palmer J.L., Keutmann H.T., Avruch J. ATP-citrate lyase. Structure of a tryptic peptide containing the phosphorylation site directed by glucagon and the cAMP-dependent protein kinase. J. Biol. Chem. 1981, 256:8867-8870.
-
(1981)
J. Biol. Chem.
, vol.256
, pp. 8867-8870
-
-
Pierce, M.W.1
Palmer, J.L.2
Keutmann, H.T.3
Avruch, J.4
-
24
-
-
65549096661
-
De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy
-
Mashima T., Seimiya H., Tsuruo T. De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy. Br. J. Cancer 2009, 100:1369-1372.
-
(2009)
Br. J. Cancer
, vol.100
, pp. 1369-1372
-
-
Mashima, T.1
Seimiya, H.2
Tsuruo, T.3
-
25
-
-
73249114946
-
Molecular mechanisms involved in farnesol-induced apoptosis
-
Joo J.H., Jetten A.M. Molecular mechanisms involved in farnesol-induced apoptosis. Cancer Lett. 2010, 287:123-135.
-
(2010)
Cancer Lett.
, vol.287
, pp. 123-135
-
-
Joo, J.H.1
Jetten, A.M.2
-
26
-
-
84858000756
-
Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
-
Metallo C.M., Gameiro P.A., Bell E.L., Mattaini K.R., Yang J., Hiller K., Jewell C.M., Johnson Z.R., Irvine D.J., Guarente L., Kelleher J.K., Vander Heiden M.G., Iliopoulos O., Stephanopoulos G. Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia. Nature 2011.
-
(2011)
Nature
-
-
Metallo, C.M.1
Gameiro, P.A.2
Bell, E.L.3
Mattaini, K.R.4
Yang, J.5
Hiller, K.6
Jewell, C.M.7
Johnson, Z.R.8
Irvine, D.J.9
Guarente, L.10
Kelleher, J.K.11
Vander Heiden, M.G.12
Iliopoulos, O.13
Stephanopoulos, G.14
-
27
-
-
84861454478
-
Reductive carboxylation supports growth in tumour cells with defective mitochondria
-
Mullen A.R., Wheaton W.W., Jin E.S., Chen P.H., Sullivan L.B., Cheng T., Yang Y., Linehan W.M., Chandel N.S., Deberardinis R.J. Reductive carboxylation supports growth in tumour cells with defective mitochondria. Nature 2011.
-
(2011)
Nature
-
-
Mullen, A.R.1
Wheaton, W.W.2
Jin, E.S.3
Chen, P.H.4
Sullivan, L.B.5
Cheng, T.6
Yang, Y.7
Linehan, W.M.8
Chandel, N.S.9
Deberardinis, R.J.10
-
28
-
-
1542304705
-
ATP-citrate lyase deficiency in the mouse
-
Beigneux A.P., Kosinski C., Gavino B., Horton J.D., Skarnes W.C., Young S.G. ATP-citrate lyase deficiency in the mouse. J. Biol. Chem. 2004, 279:9557-9564.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 9557-9564
-
-
Beigneux, A.P.1
Kosinski, C.2
Gavino, B.3
Horton, J.D.4
Skarnes, W.C.5
Young, S.G.6
-
29
-
-
34249820242
-
Metastatic progression and gene expression between breast cancer cell lines from African, American and Caucasian women
-
Yancy H.F., Mason J.A., Peters S., Thompson C.E., Littleton G.K., Jett M., Day A.A. Metastatic progression and gene expression between breast cancer cell lines from African, American and Caucasian women. J. Carcinog. 2007, 6:8.
-
(2007)
J. Carcinog.
, vol.6
, pp. 8
-
-
Yancy, H.F.1
Mason, J.A.2
Peters, S.3
Thompson, C.E.4
Littleton, G.K.5
Jett, M.6
Day, A.A.7
-
30
-
-
20444467309
-
Co-ordinate activation of lipogenic enzymes in hepatocellular carcinoma
-
Yahagi N., Shimano H., Hasegawa K., Ohashi K., Matsuzaka T., Najima Y., Sekiya M., Tomita S., Okazaki H., Tamura Y., Iizuka Y., Nagai R., Ishibashi S., Kadowaki T., Makuuchi M., Ohnishi S., Osuga J., Yamada N. Co-ordinate activation of lipogenic enzymes in hepatocellular carcinoma. Eur. J. Cancer 2005, 41:1316-1322.
-
(2005)
Eur. J. Cancer
, vol.41
, pp. 1316-1322
-
-
Yahagi, N.1
Shimano, H.2
Hasegawa, K.3
Ohashi, K.4
Matsuzaka, T.5
Najima, Y.6
Sekiya, M.7
Tomita, S.8
Okazaki, H.9
Tamura, Y.10
Iizuka, Y.11
Nagai, R.12
Ishibashi, S.13
Kadowaki, T.14
Makuuchi, M.15
Ohnishi, S.16
Osuga, J.17
Yamada, N.18
-
31
-
-
0036570356
-
Targets of gene amplification and overexpression at 17q in gastric cancer
-
Varis A., Wolf M., Monni O., Vakkari M.L., Kokkola A., Moskaluk C., Frierson H., Powell S.M., Knuutila S., Kallioniemi A., El-Rifai W. Targets of gene amplification and overexpression at 17q in gastric cancer. Cancer Res. 2002, 62:2625-2629.
-
(2002)
Cancer Res.
, vol.62
, pp. 2625-2629
-
-
Varis, A.1
Wolf, M.2
Monni, O.3
Vakkari, M.L.4
Kokkola, A.5
Moskaluk, C.6
Frierson, H.7
Powell, S.M.8
Knuutila, S.9
Kallioniemi, A.10
El-Rifai, W.11
-
32
-
-
0345448918
-
Increased activity of glycerol 3-phosphate dehydrogenase and other lipogenic enzymes in human bladder cancer
-
Turyn J., Schlichtholz B., Dettlaff-Pokora A., Presler M., Goyke E., Matuszewski M., Kmiec Z., Krajka K., Swierczynski J. Increased activity of glycerol 3-phosphate dehydrogenase and other lipogenic enzymes in human bladder cancer. Horm. Metab. Res. 2003, 35:565-569.
-
(2003)
Horm. Metab. Res.
, vol.35
, pp. 565-569
-
-
Turyn, J.1
Schlichtholz, B.2
Dettlaff-Pokora, A.3
Presler, M.4
Goyke, E.5
Matuszewski, M.6
Kmiec, Z.7
Krajka, K.8
Swierczynski, J.9
-
33
-
-
0018769394
-
Lipogenetic and glycolytic enzyme activities in carcinoma and nonmalignant diseases of the human breast
-
Szutowicz A., Kwiatkowski J., Angielski S. Lipogenetic and glycolytic enzyme activities in carcinoma and nonmalignant diseases of the human breast. Br. J. Cancer 1979, 39:681-687.
-
(1979)
Br. J. Cancer
, vol.39
, pp. 681-687
-
-
Szutowicz, A.1
Kwiatkowski, J.2
Angielski, S.3
-
35
-
-
37249016344
-
A role for ATP-citrate lyase, malic enzyme, and pyruvate/citrate cycling in glucose-induced insulin secretion
-
Guay C., Madiraju S.R., Aumais A., Joly E., Prentki M. A role for ATP-citrate lyase, malic enzyme, and pyruvate/citrate cycling in glucose-induced insulin secretion. J. Biol. Chem. 2007, 282:35657-35665.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 35657-35665
-
-
Guay, C.1
Madiraju, S.R.2
Aumais, A.3
Joly, E.4
Prentki, M.5
-
36
-
-
67349144436
-
Decreased levels of metabolic enzymes in pancreatic islets of patients with type 2 diabetes
-
MacDonald M.J., Longacre M.J., Langberg E.C., Tibell A., Kendrick M.A., Fukao T., Ostenson C.G. Decreased levels of metabolic enzymes in pancreatic islets of patients with type 2 diabetes. Diabetologia 2009, 52:1087-1091.
-
(2009)
Diabetologia
, vol.52
, pp. 1087-1091
-
-
MacDonald, M.J.1
Longacre, M.J.2
Langberg, E.C.3
Tibell, A.4
Kendrick, M.A.5
Fukao, T.6
Ostenson, C.G.7
-
37
-
-
77957795415
-
ATP-citrate lyase reduction mediates palmitate-induced apoptosis in pancreatic beta cells
-
Chu K.Y., Lin Y., Hendel A., Kulpa J.E., Brownsey R.W., Johnson J.D. ATP-citrate lyase reduction mediates palmitate-induced apoptosis in pancreatic beta cells. J. Biol. Chem. 2010, 285:32606-32615.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 32606-32615
-
-
Chu, K.Y.1
Lin, Y.2
Hendel, A.3
Kulpa, J.E.4
Brownsey, R.W.5
Johnson, J.D.6
-
38
-
-
0032529044
-
The role of ATP citrate-lyase in the metabolic regulation of plasma lipids. Hypolipidaemic effects of SB-204990, a lactone prodrug of the potent ATP citrate-lyase inhibitor SB-201076
-
Pearce N.J., Yates J.W., Berkhout T.A., Jackson B., Tew D., Boyd H., Camilleri P., Sweeney P., Gribble A.D., Shaw A., Groot P.H. The role of ATP citrate-lyase in the metabolic regulation of plasma lipids. Hypolipidaemic effects of SB-204990, a lactone prodrug of the potent ATP citrate-lyase inhibitor SB-201076. Biochem. J. 1998, 334(Pt 1):113-119.
-
(1998)
Biochem. J.
, vol.334
, Issue.PART 1
, pp. 113-119
-
-
Pearce, N.J.1
Yates, J.W.2
Berkhout, T.A.3
Jackson, B.4
Tew, D.5
Boyd, H.6
Camilleri, P.7
Sweeney, P.8
Gribble, A.D.9
Shaw, A.10
Groot, P.H.11
-
39
-
-
65449159320
-
Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice
-
Wang Q., Jiang L., Wang J., Li S., Yu Y., You J., Zeng R., Gao X., Rui L., Li W., Liu Y. Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice. Hepatology 2009, 49:1166-1175.
-
(2009)
Hepatology
, vol.49
, pp. 1166-1175
-
-
Wang, Q.1
Jiang, L.2
Wang, J.3
Li, S.4
Yu, Y.5
You, J.6
Zeng, R.7
Gao, X.8
Rui, L.9
Li, W.10
Liu, Y.11
-
40
-
-
0029852843
-
Adenosine triphosphate citrate lyase mediates hypocitraturia in rats
-
Melnick J.Z., Srere P.A., Elshourbagy N.A., Moe O.W., Preisig P.A., Alpern R.J. Adenosine triphosphate citrate lyase mediates hypocitraturia in rats. J. Clin. Invest. 1996, 98:2381-2387.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 2381-2387
-
-
Melnick, J.Z.1
Srere, P.A.2
Elshourbagy, N.A.3
Moe, O.W.4
Preisig, P.A.5
Alpern, R.J.6
|