β-amyloid peptide induces formation of actin stress fibers through p38 mitogen-activated protein kinase

Journal of Neurochemistry

Volumn 83, Issue 4, 2002, Pages 828-836

  Song, Cheng ^a   Perides, George ^b   Wang, Dechun ^a   Liu, Ya Fang ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

amyloid precursor protein; Actin stress fibers; Alzheimer's disease; Mitogen associated protein kinase associated protein kinase; p38 mitogen activated protein kinase; Presenilin 1

Indexed keywords

ACTIN; AMYLOID PRECURSOR PROTEIN; GAMMA SECRETASE; HEAT SHOCK PROTEIN 27; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE ASSOCIATED PROTEIN KINASE 2; MUTANT PROTEIN; PRESENILIN 1; PROTEIN KINASE; UNCLASSIFIED DRUG;

ACTIN POLYMERIZATION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME INHIBITION; MOUSE; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STRESS FIBER; WILD TYPE;

ACTINS; ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; CELL LINE; CELLS, CULTURED; ENDOPEPTIDASES; ENZYME INHIBITORS; HEAT-SHOCK PROTEINS; HIPPOCAMPUS; MEMBRANE PROTEINS; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION; NEOPLASM PROTEINS; NEURONS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PRESENILIN-1; PROTEIN-SERINE-THREONINE KINASES; RATS; SIGNAL TRANSDUCTION; STRESS FIBERS; TRANSFECTION;

ANIMALIA;

EID: 0036847145     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.01182.x     Document Type: Article

References (39)

1. Aksenov M. Y., Aksenova M. V., Butterfield D. A., Geddes J. W. and Markesnery W. R. (2001) Protein oxidation in the brain in Alzheimer's disease. Neuroscience 103, 373-383.
2. Benzing W. C., Wujek J. R., Ward E. K., Shaffer D., Ashe K., Younkin S. G. and Brunden K. R. (1999) Evidence for glial-mediated inflammation in aged APP(SW) transgenic mice. Neurobiol. Aging 20, 581-589.
3. Bertoni-Freddari C., Fattoretti P., Casoli T., Gambini M., Meier-Ruge W. and Ulrich J. (1992) Structural dynamics of synaptic junctional areas in aging and Alzheimer's disease. Ann. NY Acad. Sci. 673, 285-292.
4. Brown D. F., Risser R. C., Bigio E. H., Tripp P., Stiegler A., Welch E., Eagan K. P., Hladik C. L. and White C. L. III. (1998) Neocortical synapse density and Braak stage in the Lewy body variant of Alzheimer disease: A comparison with classic Alzheimer disease and normal aging. J. Neuropathol. Exp. Neurol. 57, 955-960.
5. Cabalka L. M., Hyman B. T., Goodlett C. R., Ritchie T. C. and Van Hoesen G. W. (1992) Alteration in the pattern of nerve terminal protein immunoreactivity in the perforant pathway in Alzheimer's disease and in rats after entorhinal lesions. Neurobiol. Aging 13, 283-291.
6. Chapman P. F., White G. L., Jones M. W., Cooper-Blacketer D., Marshall V. J., Irizarry M., Younkin L., Good M. A., Bliss T. V., Hyman B. T., Younkin S. G. and Hsiao K. K. (1999) Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice. Nat. Neurosci. 2, 271-276.
7. Cook D. G., Sung J. C., Golde T. E., Felsenstein K. M., Wojczyk B. S., Tanzi R. E., Trojanowski J. Q., Lee V. M. and Doms R. W. (1996) Expression and analysis of presenilin I in a human neuronal system: Localization in cell bodies and dendrites. Proc. Natl Acad. Sci. USA 93, 9223-9228.
8. Dekosky S. T. and Scheff S. W. (1990) Synapse loss in frontal cortex biopsies in Alzheimer's disease: Correlation with cognitive severity. Ann. Neuol. 27, 457-464.
9. Dewachter I., van Dorpe J., Spittaels K., Tesseur I., Van Den Haute C., Moechars D. and Van Leuven F. (2000) Modeling Alzheimer's disease in transgenic mice: Effect of age and of presenilin 1 on amyloid biochemistry and pathology in APP/London mice. Exp. Gerontol. 35, 831-841.
10. Dong C., Davis R. J. and Flavell R. A. (2002) MAP kinases in immune response. Annu. Rev. Immunol. 20, 55-72.
11. Dowjat W. K., Wisniewski T., Efthimiopoulos S. and Wisniewski H. M. (1999) Inhibition of neurite outgrowth by familial Alzheimer's disease-linked presenilin-1 mutations. Neurosci. Lett. 267, 141-144.
12. Dowjat W. K., Wisniewski H. M. and Wisniewski T. (2001) Alzheimer's disease presenilin-1 expression modulates the assembly of neurofilaments. Neuroscience 103, 1-8.
13. Eikelenboom P., Rozemullar J. M. and van Muiswinkel F. L. (1998) Inflammation and Alzheimer's disease: Relationships between pathogenic mechanisms and clinical expression. Exp. Neurol. 154, 89-98.
14. Fischer M., Kaech S., Knutti D. and Matus A. (1998) Rapid actin-based plasticity in dendritic spines. Neuron 20, 847-854.
15. Fischer M., Kaech S., Wagner U., Brinkhaus H. and Matus A. (2000) Glutamate receptors regulate actin-based plasticity in dendritic spines. Nat. Neurosci. 3, 887-894.
16. 2+ influx. J. Neurochem. 65, 1061-1068.
17. 2+]. Exp. Neurol. 133, 153-163.
18. Furukawa K., Fu W., Li Y., Witke W., Kwiatkowski D. J. and Mattson M. P. (1997) The actin-severing protein gelsolin modulates calcium channel and NMDA receptor activities and vulnerability to excitotoxicity in hippocampal neurons. J. Neurosci. 17, 8178-8186.
19. Greengard P., Valtorta F., Czernik A. J. and Benfenati F. (1993) Synaptic vesicle phosphoproteins and regulation of synaptic function. Science 259, 780-785.
20. Hasbani M. J., Schlief M. L., Fisher D. A. and Goldberg M. P. (2001) Dendritic spines lost during glutamate receptor activation reemerge at original sites of synaptic contact. J. Neurosci. 21, 2393-2403.
21. Huot J., Houle F., Rousseau S., Deschesnes R. G., Shah G. M. and Landry J. (2000) SAPK2/p38-dependent F-actin reorganization regulates early membrane blebbing during stress-induced apoptosis. J. Cell Biol. 143, 1361-1473.
22. Lee H. J., Hammond D. N., Large T. H. and Wainer B. H. (1990) Immortalized young adult neurons from the septal region: Generation and characterization. Brain Res. Dev. Brain Res. 52, 219-228.
23. Liu Y. F. (1998) Expression of polyglutamine-expanded Huntingtin activates the SEK1-JNK pathway and induces apoptosis in a hippocampal neuronal cell line. J. Biol. Chem. 273, 28873-28877.
24. Marin N., Romero B., Bosch-Morell F., Llansola M., Felipo V., Roma J. and Romero F. J. (2000) Beta-amyloid-induced activation of caspase-3 in primary cultures of rat neurons. Mech. Ageing Dev. 119, 63-67.
25. Masliah E., Heaton R. K., Marcotte T. D., Ellis R. J., Wiley C. A., Mallory M., Achim C. L., McCutchan J. A., Nelson J. A., Atkinson J. H., Grant I. and HNRC Group (1997) Dendritic injury is a pathological substrate for human immunodeficiency virus-related cognitive disorders. Ann. Neurol. 42, 963-972.
26. Matus A. (2000) Actin-based plasticity in dendritic spines. Science 290, 754-758.
27. Meberg P. and Bamburg J. R. (2000) Increase in neurite outgrowth mediated by overexpression of actin depolymerizing factor. J. Neurosci. 20, 2459-2469.
28. Minamide L. S., Striegl A. M., Boyle J. A., Meberg P. J. and Bamburg J. R. (2000) Neurodegenerative stimuli induce persistent ADF-cofilin-actin rods that disrupts distal neurite function. Nat. Cell Biol. 2, 628-636.
29. Price D. L. and Sisodia S. S. (1998) Mutant genes in familial Alzheimer's disease and transgenic models. Annu. Rev. Neurosci. 21, 479-505.
30. Price D. L., Tanzi R. E., Borchelt D. R. and Sisodia S. S. (1998) Alzheimer's disease: genetic studies and transgenic models. Annu. Rev. Genet 32, 461-493.
31. Purpura D. P. (1974) Dendritic spine 'dysgenesis' and mental retardation. Science 186, 1126-1128.
32. Rincon M., Flavell R. A. and Davis R. A. (2000) The JNK and P38 MAP kinase signaling pathways in T cell-mediated immune responses. Free Radic. Biol. Med. 28, 1328-1337.
33. Rousseau S., Houle F., Landry J. and Huot J. (1997) p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells. Oncogene 15, 2169-2177.
34. Scheff S. W., DeKosky S. T. and Price D. A. (1990) Quantitative assessment of cortical synaptic density in Alzheimer's disease. Neurobiol. Aging 11, 29-37.
35. Selkoe D. J. (2000) The genetics and molecular pathology of Alzheimer's disease: Roles of amyloid and the presenilins. Neurol. Clin. 18, 903-922.
36. Stephan A., Laroche S. and Davis S. (2001) Generation of aggregated beta-amyloid in the rat hippocampus impairs synaptic transmission and plasticity and causes memory deficits. J. Neurosci. 21, 5703-5714.
37. Tanzi R. E. and Bertram L. (2001) New frontiers in Alzheimer's disease genetics. Neuron 32, 181-184.
38. Terry R. D., Masliah E., Salmon D. P., Butters N., DeTeresa R., Hill R., Hansen L. A. and Katzman R. (1991) Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment. Ann. Neurol. 30, 572-580.
39. Toni N., Buchs P. A., Nikonenko I., Bron C. R. and Muller D. (1999) LTP promotes formation of multiple spine synapses between a single axon terminal and a dendrite. Nature 402, 421-425.