The GABA shunt: An attractive and potential therapeutic target in the treatment of epileptic disorders

Current Drug Metabolism

Volumn 6, Issue 2, 2005, Pages 127-139

  Yogeeswari, P ^a   Sriram, D ^a   Vaigundaragavendran, J ^a  

^a BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

Author keywords

GABA; GABA transaminase; Glutamic acid decarboxylase; Succinic semialdehyde dehyrogenase; TCA cycle; Valproic acid; Vigabatrin

Indexed keywords

4 AMINOBUTYRATE AMINOTRANSFERASE; 4 AMINOBUTYRATE AMINOTRANSFERASE INHIBITOR; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID DERIVATIVE; ACETAZOLAMIDE; ANTICONVULSIVE AGENT; BECLAMIDE; BILOBALIDE; CARBAMAZEPINE; DIAZEPAM; ETHOSUXIMIDE; ETIRACETAM; FLAVONOID; GABACULINE; GABAPENTIN; GINKGO BILOBA EXTRACT; GINKGOLIDE; GLUTAMATE DECARBOXYLASE; GLUTAMIC ACID; LAMOTRIGINE; PHENELZINE; PHENYTOIN; RETIGABINE; SUCCINATE SEMIALDEHYDE DEHYDROGENASE; SUCCINATE SEMIALDEHYDE DEHYDROGENASE INHIBITOR; TIAGABINE; TOPIRAMATE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALPROIC ACID; VIGABATRIN;

ABSENCE; ANTICONVULSANT ACTIVITY; BRAIN DISEASE; CENTRAL NERVOUS SYSTEM DISEASE; DISEASE CONTROL; DOSE RESPONSE; DRUG BINDING; DRUG EFFICACY; DRUG MECHANISM; DRUG STRUCTURE; DRUG TARGETING; EPILEPSY; FOCAL EPILEPSY; GABAERGIC SYSTEM; GABAERGIC TRANSMISSION; GENERALIZED EPILEPSY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; NEUROPROTECTION; NONHUMAN; PATHOPHYSIOLOGY; REVIEW; TONIC SEIZURE;

ANIMALS; ANTICONVULSANTS; BRAIN; DRUG DELIVERY SYSTEMS; EPILEPSY; GAMMA-AMINOBUTYRIC ACID; HUMANS;

EID: 15444370317     PISSN: 13892002     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389200053586073     Document Type: Review

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