메뉴 건너뛰기




Volumn 91, Issue 2, 2011, Pages 603-649

Epigenetic Regulation of Gene Expression in Physiological and Pathological Brain Processes

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; COCAINE; DNA; HISTONE DEACETYLASE INHIBITOR; IMIPRAMINE; MORPHINE; RNA;

EID: 79955622702     PISSN: 00319333     EISSN: 15221210     Source Type: Journal    
DOI: 10.1152/physrev.00012.2010     Document Type: Article
Times cited : (297)

References (372)
  • 2
    • 38649124003 scopus 로고    scopus 로고
    • Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders
    • Abel T, Zukin RS. Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders. Curr Opin Pharmacol 8: 57-64, 2008.
    • (2008) Curr Opin Pharmacol , vol.8 , pp. 57-64
    • Abel, T.1    Zukin, R.S.2
  • 3
    • 65249109439 scopus 로고    scopus 로고
    • MeCP2-mediated transcription repression in the basolateral amygdala may underlie heightened anxiety in a mouse model of Rett syndrome
    • Adachi M, Autry AE, Covington HE 3rd, Monteggia LM. MeCP2-mediated transcription repression in the basolateral amygdala may underlie heightened anxiety in a mouse model of Rett syndrome. J Neurosci 29: 4218-4227, 2009.
    • (2009) J Neurosci , vol.29 , pp. 4218-4227
    • Adachi, M.1    Autry, A.E.2    Covington III, H.E.3    Monteggia, L.M.4
  • 4
    • 0032734510 scopus 로고    scopus 로고
    • DNA strand breaks in Alzheimer's disease
    • Adamec E, Vonsattel JP, Nixon RA. DNA strand breaks in Alzheimer's disease. Brain Res 849: 67-77, 1999.
    • (1999) Brain Res , vol.849 , pp. 67-77
    • Adamec, E.1    Vonsattel, J.P.2    Nixon, R.A.3
  • 6
    • 2942705826 scopus 로고    scopus 로고
    • Chromatin acetylation, memory, and LTP are impaired in CBP /- mice: A model for the cognitive defi{ligature}cit in Rubinstein-Taybi syndrome and its amelioration
    • Alarcon JM, Malleret G, Touzani K, Vronskaya S, Ishii S, Kandel ER, Barco A. Chromatin acetylation, memory, and LTP are impaired in CBP /- mice: a model for the cognitive defi{ligature}cit in Rubinstein-Taybi syndrome and its amelioration. Neuron 42: 947-959, 2004.
    • (2004) Neuron , vol.42 , pp. 947-959
    • Alarcon, J.M.1    Malleret, G.2    Touzani, K.3    Vronskaya, S.4    Ishii, S.5    Kandel, E.R.6    Barco, A.7
  • 7
    • 77950689477 scopus 로고    scopus 로고
    • Differential expression of glucocorticoid receptor transcripts in major depressive disorder is not epigenetically programmed
    • Alt SR, Turner JD, Klok MD, Meijer OC, Lakke EA, Derijk RH, Muller CP. Differential expression of glucocorticoid receptor transcripts in major depressive disorder is not epigenetically programmed. Psychoneuroendocrinology 35: 544-556, 2010.
    • (2010) Psychoneuroendocrinology , vol.35 , pp. 544-556
    • Alt, S.R.1    Turner, J.D.2    Klok, M.D.3    Meijer, O.C.4    Lakke, E.A.5    Derijk, R.H.6    Muller, C.P.7
  • 8
    • 0032830639 scopus 로고    scopus 로고
    • Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
    • Amir RE, Van den Veyver IB, Wan M, Tran CQ, Francke U, Zoghbi HY. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat Genet 23: 185-188, 1999.
    • (1999) Nat Genet , vol.23 , pp. 185-188
    • Amir, R.E.1    Van den Veyver, I.B.2    Wan, M.3    Tran, C.Q.4    Francke, U.5    Zoghbi, H.Y.6
  • 12
    • 34548202642 scopus 로고    scopus 로고
    • Nap1l2 promotes histone acetylation activity during neuronal differentiation
    • Attia M, Rachez C, De Pauw A, Avner P, Rogner UC. Nap1l2 promotes histone acetylation activity during neuronal differentiation. Mol Cell Biol 27: 6093-6102, 2007.
    • (2007) Mol Cell Biol , vol.27 , pp. 6093-6102
    • Attia, M.1    Rachez, C.2    de Pauw, A.3    Avner, P.4    Rogner, U.C.5
  • 14
    • 11844279705 scopus 로고    scopus 로고
    • DNA methyltransferase 3b regulates nerve growth factor-induced differentiation of PC12 cells by recruiting histone deacetylase 2
    • Bai S, Ghoshal K, Datta J, Majumder S, Yoon SO, Jacob ST. DNA methyltransferase 3b regulates nerve growth factor-induced differentiation of PC12 cells by recruiting histone deacetylase 2. Mol Cell Biol 25: 751-766, 2005.
    • (2005) Mol Cell Biol , vol.25 , pp. 751-766
    • Bai, S.1    Ghoshal, K.2    Datta, J.3    Majumder, S.4    Yoon, S.O.5    Jacob, S.T.6
  • 16
    • 19344378337 scopus 로고    scopus 로고
    • REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis
    • Ballas N, Grunseich C, Lu DD, Speh JC, Mandel G. REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. Cell 121: 645-657, 2005.
    • (2005) Cell , vol.121 , pp. 645-657
    • Ballas, N.1    Grunseich, C.2    Lu, D.D.3    Speh, J.C.4    Mandel, G.5
  • 17
    • 25844518743 scopus 로고    scopus 로고
    • The many faces of REST oversee epigenetic programming of neuronal genes
    • Ballas N, Mandel G. The many faces of REST oversee epigenetic programming of neuronal genes. Curr Opin Neurobiol 15: 500-506, 2005.
    • (2005) Curr Opin Neurobiol , vol.15 , pp. 500-506
    • Ballas, N.1    Mandel, G.2
  • 18
    • 44749084727 scopus 로고    scopus 로고
    • The cognitive neuroscience of working memory: Relevance to CNTRICS and schizophrenia
    • Barch DM, Smith E. The cognitive neuroscience of working memory: relevance to CNTRICS and schizophrenia. Biol Psychiatry 64: 11-17, 2008.
    • (2008) Biol Psychiatry , vol.64 , pp. 11-17
    • Barch, D.M.1    Smith, E.2
  • 19
    • 0035997356 scopus 로고    scopus 로고
    • ATP-dependent nucleosome remodeling
    • Becker PB, Horz W. ATP-dependent nucleosome remodeling. Annu Rev Biochem 71: 247-273, 2002.
    • (2002) Annu Rev Biochem , vol.71 , pp. 247-273
    • Becker, P.B.1    Horz, W.2
  • 20
    • 65349122404 scopus 로고    scopus 로고
    • Widespread changes in dendritic and axonal morphology in Mecp2-mutant mouse models of Rett syndrome: Evidence for disruption of neuronal networks
    • Belichenko PV, Wright EE, Belichenko NP, Masliah E, Li HH, Mobley WC, Francke U. Widespread changes in dendritic and axonal morphology in Mecp2-mutant mouse models of Rett syndrome: evidence for disruption of neuronal networks. J Comp Neurol 514: 240-258, 2009.
    • (2009) J Comp Neurol , vol.514 , pp. 240-258
    • Belichenko, P.V.1    Wright, E.E.2    Belichenko, N.P.3    Masliah, E.4    Li, H.H.5    Mobley, W.C.6    Francke, U.7
  • 21
    • 4344573714 scopus 로고    scopus 로고
    • Adult neuron survival strategies-slamming on the brakes
    • Benn SC, Woolf CJ. Adult neuron survival strategies-slamming on the brakes. Nat Rev Neurosci 5: 686-700, 2004.
    • (2004) Nat Rev Neurosci , vol.5 , pp. 686-700
    • Benn, S.C.1    Woolf, C.J.2
  • 23
    • 48749105928 scopus 로고    scopus 로고
    • Physical and mental health outcomes of prenatal maternal stress in human and animal studies: A review of recent evidence
    • Beydoun H, Saftlas AF. Physical and mental health outcomes of prenatal maternal stress in human and animal studies: a review of recent evidence. Paediatr Perinat Epidemiol 22: 438-466, 2008.
    • (2008) Paediatr Perinat Epidemiol , vol.22 , pp. 438-466
    • Beydoun, H.1    Saftlas, A.F.2
  • 25
    • 26944473609 scopus 로고    scopus 로고
    • Psychological stress increases histone H3 phosphorylation in adult dentate gyrus granule neurons: Involvement in a glucocorticoid receptor-dependent behavioural response
    • Bilang-Bleuel A, Ulbricht S, Chandramohan Y, De Carli S, Droste SK, Reul JMHM. Psychological stress increases histone H3 phosphorylation in adult dentate gyrus granule neurons: involvement in a glucocorticoid receptor-dependent behavioural response. Eur J Neurosci 22: 1691-1700, 2005.
    • (2005) Eur J Neurosci , vol.22 , pp. 1691-1700
    • Bilang-Bleuel, A.1    Ulbricht, S.2    Chandramohan, Y.3    de Carli, S.4    Droste, S.K.5    Reul, J.M.H.M.6
  • 26
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • Bird A. DNA methylation patterns and epigenetic memory. Genes Dev 16: 6-21, 2002.
    • (2002) Genes Dev , vol.16 , pp. 6-21
    • Bird, A.1
  • 27
    • 34249337761 scopus 로고    scopus 로고
    • Perceptions of epigenetics
    • Bird A. Perceptions of epigenetics. Nature 447: 396-398, 2007.
    • (2007) Nature , vol.447 , pp. 396-398
    • Bird, A.1
  • 28
    • 0027476024 scopus 로고
    • A synaptic model of memory: Long-term potentiation in the hippocampus
    • Bliss TV, Collingridge GL. A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361: 31-39, 1993.
    • (1993) Nature , vol.361 , pp. 31-39
    • Bliss, T.V.1    Collingridge, G.L.2
  • 29
    • 33751282353 scopus 로고    scopus 로고
    • Huntington's disease: From huntingtin function and dysfunction to therapeutic strategies
    • Borrell-Pages M, Zala D, Humbert S, Saudou F. Huntington's disease: from huntingtin function and dysfunction to therapeutic strategies. Cell Mol Life Sci 63: 2642-2660, 2006.
    • (2006) Cell Mol Life Sci , vol.63 , pp. 2642-2660
    • Borrell-Pages, M.1    Zala, D.2    Humbert, S.3    Saudou, F.4
  • 30
    • 0027459863 scopus 로고
    • Characterisation of LTP induced by the activation of glutamate metabotropic receptors in area CA1 of the hippocampus
    • Bortolotto ZA, Collingridge GL. Characterisation of LTP induced by the activation of glutamate metabotropic receptors in area CA1 of the hippocampus. Neuropharmacology 32: 1-9, 1993.
    • (1993) Neuropharmacology , vol.32 , pp. 1-9
    • Bortolotto, Z.A.1    Collingridge, G.L.2
  • 31
    • 0028826921 scopus 로고
    • Changes in core histone variant composition in differentiating neurons: The roles of differential turnover and synthesis rates
    • Bosch A, Suau P. Changes in core histone variant composition in differentiating neurons: the roles of differential turnover and synthesis rates. Eur J Cell Biol 68: 220-225, 1995.
    • (1995) Eur J Cell Biol , vol.68 , pp. 220-225
    • Bosch, A.1    Suau, P.2
  • 34
    • 38649140454 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor valproic acid enhances acquisition, extinction, and reconsolidation of conditioned fear
    • Bredy TW, Barad M. The histone deacetylase inhibitor valproic acid enhances acquisition, extinction, and reconsolidation of conditioned fear. Learn Mem 15: 39-45, 2008.
    • (2008) Learn Mem , vol.15 , pp. 39-45
    • Bredy, T.W.1    Barad, M.2
  • 35
    • 34247224239 scopus 로고    scopus 로고
    • Histone modifi{ligature}cations around individual BDNF gene promoters in prefrontal cortex are associated with extinction of conditioned fear
    • Bredy TW, Wu H, Crego C, Zellhoefer J, Sun YE, Barad M. Histone modifi{ligature}cations around individual BDNF gene promoters in prefrontal cortex are associated with extinction of conditioned fear. Learn Mem 14: 268-276, 2007.
    • (2007) Learn Mem , vol.14 , pp. 268-276
    • Bredy, T.W.1    Wu, H.2    Crego, C.3    Zellhoefer, J.4    Sun, Y.E.5    Barad, M.6
  • 37
    • 0029925512 scopus 로고    scopus 로고
    • Special HATs for special occasions: Linking histone acetylation to chromatin assembly and gene activation
    • Brownell JE, Allis CD. Special HATs for special occasions: linking histone acetylation to chromatin assembly and gene activation. Curr Opin Genet Dev 6: 176-184, 1996.
    • (1996) Curr Opin Genet Dev , vol.6 , pp. 176-184
    • Brownell, J.E.1    Allis, C.D.2
  • 39
    • 33748928786 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors as therapeutics for polyglutamine disorders
    • Butler R, Bates GP. Histone deacetylase inhibitors as therapeutics for polyglutamine disorders. Nat Rev Neurosci 7: 784-796, 2006.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 784-796
    • Butler, R.1    Bates, G.P.2
  • 40
    • 0035816661 scopus 로고    scopus 로고
    • A transcriptionally active complex of APP with Fe65 and histone acetyltransferase Tip60
    • Cao X, Sudhof TC. A transcriptionally active complex of APP with Fe65 and histone acetyltransferase Tip60. Science 293: 115-120, 2001.
    • (2001) Science , vol.293 , pp. 115-120
    • Cao, X.1    Sudhof, T.C.2
  • 42
    • 28844473025 scopus 로고    scopus 로고
    • Novel targets for valproic acid: Up-regulation of melatonin receptors and neurotrophic factors in C6 glioma cells
    • Castro LM, Gallant M, Niles LP. Novel targets for valproic acid: up-regulation of melatonin receptors and neurotrophic factors in C6 glioma cells. J Neurochem 95: 1227-1236, 2005.
    • (2005) J Neurochem , vol.95 , pp. 1227-1236
    • Castro, L.M.1    Gallant, M.2    Niles, L.P.3
  • 43
    • 67349190247 scopus 로고    scopus 로고
    • Linking DNA methylation and histone modifi{ligature}cation: Patterns and paradigms
    • Cedar H, Bergman Y. Linking DNA methylation and histone modifi{ligature}cation: patterns and paradigms. Nat Rev Genet 10: 295-304, 2009.
    • (2009) Nat Rev Genet , vol.10 , pp. 295-304
    • Cedar, H.1    Bergman, Y.2
  • 44
    • 45849105557 scopus 로고    scopus 로고
    • MeCP2, a key contributor to neurological disease, activates and represses transcription
    • Chahrour M, Jung SY, Shaw C, Zhou X, Wong ST, Qin J, Zoghbi HY. MeCP2, a key contributor to neurological disease, activates and represses transcription. Science 320: 1224-1229, 2008.
    • (2008) Science , vol.320 , pp. 1224-1229
    • Chahrour, M.1    Jung, S.Y.2    Shaw, C.3    Zhou, X.4    Wong, S.T.5    Qin, J.6    Zoghbi, H.Y.7
  • 45
    • 0041733266 scopus 로고    scopus 로고
    • Variations in maternal care in the rat as a mediating infl{ligature}uence for the effects of environment on development
    • Champagne FA, Francis DD, Mar A, Meaney MJ. Variations in maternal care in the rat as a mediating infl{ligature}uence for the effects of environment on development. Physiol Behav 79: 359-371, 2003.
    • (2003) Physiol Behav , vol.79 , pp. 359-371
    • Champagne, F.A.1    Francis, D.D.2    Mar, A.3    Meaney, M.J.4
  • 46
    • 31444434393 scopus 로고    scopus 로고
    • The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression
    • Chang Q, Khare G, Dani V, Nelson S, Jaenisch R. The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression. Neuron 49: 341-348, 2006.
    • (2006) Neuron , vol.49 , pp. 341-348
    • Chang, Q.1    Khare, G.2    Dani, V.3    Nelson, S.4    Jaenisch, R.5
  • 47
    • 0032956630 scopus 로고    scopus 로고
    • The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS
    • Chen G, Zeng WZ, Yuan PX, Huang LD, Jiang YM, Zhao ZH, Manji HK. The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS. J Neurochem 72: 879-882, 1999.
    • (1999) J Neurochem , vol.72 , pp. 879-882
    • Chen, G.1    Zeng, W.Z.2    Yuan, P.X.3    Huang, L.D.4    Jiang, Y.M.5    Zhao, Z.H.6    Manji, H.K.7
  • 48
    • 34748922275 scopus 로고    scopus 로고
    • Valproic acid and other histone deacetylase inhibitors induce microglial apoptosis and attenuate lipopolysaccharide-induced dopaminergic neurotoxicity
    • Chen PS, Wang CC, Bortner CD, Peng GS, Wu X, Pang H, Lu RB, Gean PW, Chuang DM, Hong JS. Valproic acid and other histone deacetylase inhibitors induce microglial apoptosis and attenuate lipopolysaccharide-induced dopaminergic neurotoxicity. Neuroscience 149: 203-212, 2007.
    • (2007) Neuroscience , vol.149 , pp. 203-212
    • Chen, P.S.1    Wang, C.C.2    Bortner, C.D.3    Peng, G.S.4    Wu, X.5    Pang, H.6    Lu, R.B.7    Gean, P.W.8    Chuang, D.M.9    Hong, J.S.10
  • 49
    • 0035093830 scopus 로고    scopus 로고
    • Defi{ligature}ciency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice
    • Chen RZ, Akbarian S, Tudor M, Jaenisch R. Defi{ligature}ciency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice. Nat Genet 27: 327-331, 2001.
    • (2001) Nat Genet , vol.27 , pp. 327-331
    • Chen, R.Z.1    Akbarian, S.2    Tudor, M.3    Jaenisch, R.4
  • 51
    • 39749165022 scopus 로고    scopus 로고
    • NGF/PI3K signaling-mediated epigenetic regulation of delta opioid receptor gene expression
    • Chen YL, Law PY, Loh HH. NGF/PI3K signaling-mediated epigenetic regulation of delta opioid receptor gene expression. Biochem Biophys Res Commun 368: 755-760, 2008.
    • (2008) Biochem Biophys Res Commun , vol.368 , pp. 755-760
    • Chen, Y.L.1    Law, P.Y.2    Loh, H.H.3
  • 52
    • 0031694917 scopus 로고    scopus 로고
    • NRSF/REST is required in vivo for repression of multiple neuronal target genes during embryogenesis
    • Chen ZF, Paquette AJ, Anderson DJ. NRSF/REST is required in vivo for repression of multiple neuronal target genes during embryogenesis. Nat Genet 20: 136-142, 1998.
    • (1998) Nat Genet , vol.20 , pp. 136-142
    • Chen, Z.F.1    Paquette, A.J.2    Anderson, D.J.3
  • 53
    • 77952888242 scopus 로고    scopus 로고
    • DNA methylation in vulnerability to post-traumatic stress in rats: Evidence for the role of the post-synaptic density protein Dlgap2
    • Chertkow-Deutsher Y, Cohen H, Klein E, Ben-Shachar D. DNA methylation in vulnerability to post-traumatic stress in rats: evidence for the role of the post-synaptic density protein Dlgap2. Int J Neuropsychopharmacol: 1-13, 2009.
    • (2009) Int J Neuropsychopharmacol , pp. 1-13
    • Chertkow-Deutsher, Y.1    Cohen, H.2    Klein, E.3    Ben-Shachar, D.4
  • 55
    • 0032741429 scopus 로고    scopus 로고
    • Synergistic effect of histone hyperacetylation and DNA demethylation in the reactivation of the FMR1 gene
    • Chiurazzi P, Pomponi MG, Pietrobono R, Bakker CE, Neri G, Oostra BA. Synergistic effect of histone hyperacetylation and DNA demethylation in the reactivation of the FMR1 gene. Hum Mol Genet 8: 2317-2323, 1999.
    • (1999) Hum Mol Genet , vol.8 , pp. 2317-2323
    • Chiurazzi, P.1    Pomponi, M.G.2    Pietrobono, R.3    Bakker, C.E.4    Neri, G.5    Oostra, B.A.6
  • 58
    • 36249006058 scopus 로고    scopus 로고
    • The nuclear kinase mitogen- and stress-activated protein kinase 1 regulates hippocampal chromatin remodeling in memory formation
    • Chwang WB, Arthur JS, Schumacher A, Sweatt JD. The nuclear kinase mitogen- and stress-activated protein kinase 1 regulates hippocampal chromatin remodeling in memory formation. J Neurosci 27: 12732-12742, 2007.
    • (2007) J Neurosci , vol.27 , pp. 12732-12742
    • Chwang, W.B.1    Arthur, J.S.2    Schumacher, A.3    Sweatt, J.D.4
  • 59
    • 33744793463 scopus 로고    scopus 로고
    • ERK/ MAPK regulates hippocampal histone phosphorylation following contextual fear conditioning
    • Chwang WB, O'Riordan KJ, Levenson JM, Sweatt JD. ERK/ MAPK regulates hippocampal histone phosphorylation following contextual fear conditioning. Learning Memory 13: 322-328, 2006.
    • (2006) Learning Memory , vol.13 , pp. 322-328
    • Chwang, W.B.1    O'Riordan, K.J.2    Levenson, J.M.3    Sweatt, J.D.4
  • 60
    • 63049117086 scopus 로고    scopus 로고
    • Exercise improves cognitive responses to psychological stress through enhancement of epigenetic mechanisms and gene expression in the dentate gyrus
    • Collins A, Hill LE, Chandramohan Y, Whitcomb D, Droste SK, Reul JM. Exercise improves cognitive responses to psychological stress through enhancement of epigenetic mechanisms and gene expression in the dentate gyrus. PLoS One 4: e4330, 2009.
    • (2009) PLoS One , vol.e4330 , pp. 4
    • Collins, A.1    Hill, L.E.2    Chandramohan, Y.3    Whitcomb, D.4    Droste, S.K.5    Reul, J.M.6
  • 62
    • 70449650339 scopus 로고    scopus 로고
    • Epigenetic mechanisms facilitating oligodendrocyte development, maturation, and aging
    • Copray S, Huynh JL, Sher F, Casaccia-Bonnefil P, Boddeke E. Epigenetic mechanisms facilitating oligodendrocyte development, maturation, and aging. Glia 57: 1579-1587, 2009.
    • (2009) Glia , vol.57 , pp. 1579-1587
    • Copray, S.1    Huynh, J.L.2    Sher, F.3    Casaccia-Bonnefil, P.4    Boddeke, E.5
  • 65
    • 0029967152 scopus 로고    scopus 로고
    • Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatin condensation
    • Costello JF, Berger MS, Huang HS, Cavenee WK. Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatin condensation. Cancer Res 56: 2405-2410, 1996.
    • (1996) Cancer Res , vol.56 , pp. 2405-2410
    • Costello, J.F.1    Berger, M.S.2    Huang, H.S.3    Cavenee, W.K.4
  • 67
    • 36849154193 scopus 로고
    • Neurobiology: Memory and molecular turnover
    • Crick F. Neurobiology: memory and molecular turnover. Nature 312: 101, 1984.
    • (1984) Nature , vol.312 , pp. 101
    • Crick, F.1
  • 68
    • 0348143169 scopus 로고    scopus 로고
    • Chromatin remodeling and neuronal response: Multiple signaling pathways induce specifi{ligature}c histone H3 modifi{ligature}cations and early gene expression in hippocampal neurons
    • Crosio C, Heitz E, Allis CD, Borrelli E, Sassone-Corsi P. Chromatin remodeling and neuronal response: multiple signaling pathways induce specifi{ligature}c histone H3 modifi{ligature}cations and early gene expression in hippocampal neurons. J Cell Sci 116: 4905-4914, 2003.
    • (2003) J Cell Sci , vol.116 , pp. 4905-4914
    • Crosio, C.1    Heitz, E.2    Allis, C.D.3    Borrelli, E.4    Sassone-Corsi, P.5
  • 69
    • 0345405447 scopus 로고    scopus 로고
    • Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofi{ligature}brillary tangles
    • Cruz JC, Tseng HC, Goldman JA, Shih H, Tsai LH. Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofi{ligature}brillary tangles. Neuron 40: 471-483, 2003.
    • (2003) Neuron , vol.40 , pp. 471-483
    • Cruz, J.C.1    Tseng, H.C.2    Goldman, J.A.3    Shih, H.4    Tsai, L.H.5
  • 70
    • 74449087422 scopus 로고    scopus 로고
    • Maternal separation alters nerve growth factor and corticosterone levels but not the DNA methylation status of the exon 1(7) glucocorticoid receptor promoter region
    • Daniels WM, Fairbairn LR, van Tilburg G, McEvoy CR, Zigmond MJ, Russell VA, Stein DJ. Maternal separation alters nerve growth factor and corticosterone levels but not the DNA methylation status of the exon 1(7) glucocorticoid receptor promoter region. Metab Brain Dis 24: 615-627, 2009.
    • (2009) Metab Brain Dis , vol.24 , pp. 615-627
    • Daniels, W.M.1    Fairbairn, L.R.2    van Tilburg, G.3    McEvoy, C.R.4    Zigmond, M.J.5    Russell, V.A.6    Stein, D.J.7
  • 71
    • 40849124149 scopus 로고    scopus 로고
    • Epigenetic programming of the stress response in male and female rats by prenatal restraint stress
    • Darnaudery M, Maccari S. Epigenetic programming of the stress response in male and female rats by prenatal restraint stress. Brain Res Rev 57: 571-585, 2008.
    • (2008) Brain Res Rev , vol.57 , pp. 571-585
    • Darnaudery, M.1    Maccari, S.2
  • 72
    • 68349152772 scopus 로고    scopus 로고
    • Histone deactylase inhibition combined with behavioral therapy enhances learning and memory following traumatic brain injury
    • Dash PK, Orsi SA, Moore AN. Histone deactylase inhibition combined with behavioral therapy enhances learning and memory following traumatic brain injury. Neuroscience 163: 1-8, 2009.
    • (2009) Neuroscience , vol.163 , pp. 1-8
    • Dash, P.K.1    Orsi, S.A.2    Moore, A.N.3
  • 73
    • 77958580776 scopus 로고    scopus 로고
    • DNA methylation and memory formation
    • Day JJ, Sweatt JD. DNA methylation and memory formation. Nat Neurosci 13: 1319-1323, 2010.
    • (2010) Nat Neurosci , vol.13 , pp. 1319-1323
    • Day, J.J.1    Sweatt, J.D.2
  • 74
    • 77956167928 scopus 로고    scopus 로고
    • MeCP2 in the nucleus accumbens contributes to neural and behavioral responses to psychostimulants
    • Deng JV, Rodriguiz RM, Hutchinson AN, Kim IH, Wetsel WC, West AE. MeCP2 in the nucleus accumbens contributes to neural and behavioral responses to psychostimulants. Nat Neurosci 13: 1128-1136, 2010.
    • (2010) Nat Neurosci , vol.13 , pp. 1128-1136
    • Deng, J.V.1    Rodriguiz, R.M.2    Hutchinson, A.N.3    Kim, I.H.4    Wetsel, W.C.5    West, A.E.6
  • 75
    • 17244368913 scopus 로고    scopus 로고
    • Genomic characterization reveals a simple histone H4 acetylation code
    • Dion MF, Altschuler SJ, Wu LF, Rando OJ. Genomic characterization reveals a simple histone H4 acetylation code. Proc Natl Acad Sci USA 102: 5501-5506, 2005.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 5501-5506
    • Dion, M.F.1    Altschuler, S.J.2    Wu, L.F.3    Rando, O.J.4
  • 77
    • 34047175919 scopus 로고    scopus 로고
    • Histone deacetylase 6 inhibition compensates for the transport defi{ligature}cit in Huntington's disease by increasing tubulin acetylation
    • Dompierre JP, Godin JD, Charrin BC, Cordelieres FP, King SJ, Humbert S, Saudou F. Histone deacetylase 6 inhibition compensates for the transport defi{ligature}cit in Huntington's disease by increasing tubulin acetylation. J Neurosci 27: 3571-3583, 2007.
    • (2007) J Neurosci , vol.27 , pp. 3571-3583
    • Dompierre, J.P.1    Godin, J.D.2    Charrin, B.C.3    Cordelieres, F.P.4    King, S.J.5    Humbert, S.6    Saudou, F.7
  • 78
    • 77955046461 scopus 로고    scopus 로고
    • SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10
    • Donmez G, Wang D, Cohen DE, Guarente L. SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10. Cell 142: 320-332, 2010.
    • (2010) Cell , vol.142 , pp. 320-332
    • Donmez, G.1    Wang, D.2    Cohen, D.E.3    Guarente, L.4
  • 79
    • 0029157378 scopus 로고
    • Evolution of the SNF2 family of proteins: Subfamilies with distinct sequences and functions
    • Eisen JA, Sweder KS, Hanawalt PC. Evolution of the SNF2 family of proteins: subfamilies with distinct sequences and functions. Nucleic Acids Res 23: 2715-2723, 1995.
    • (1995) Nucleic Acids Res , vol.23 , pp. 2715-2723
    • Eisen, J.A.1    Sweder, K.S.2    Hanawalt, P.C.3
  • 80
    • 70349733198 scopus 로고    scopus 로고
    • Chronic dietary administration of valproic acid protects neurons of the rat nucleus basalis magnocellularis from ibotenic acid neurotoxicity
    • Eleuteri S, Monti B, Brignani S, Contestabile A. Chronic dietary administration of valproic acid protects neurons of the rat nucleus basalis magnocellularis from ibotenic acid neurotoxicity. Neurotox Res 15: 127-132, 2009.
    • (2009) Neurotox Res , vol.15 , pp. 127-132
    • Eleuteri, S.1    Monti, B.2    Brignani, S.3    Contestabile, A.4
  • 82
    • 33751120697 scopus 로고    scopus 로고
    • Pharmacological inhibition of histone deacetylases by suberoylanilide hydroxamic acid specifi{ligature}cally alters gene expression and reduces ischemic injury in the mouse brain
    • Faraco G, Pancani T, Formentini L, Mascagni P, Fossati G, Leoni F, Moroni F, Chiarugi A. Pharmacological inhibition of histone deacetylases by suberoylanilide hydroxamic acid specifi{ligature}cally alters gene expression and reduces ischemic injury in the mouse brain. Mol Pharmacol 70: 1876-1884, 2006.
    • (2006) Mol Pharmacol , vol.70 , pp. 1876-1884
    • Faraco, G.1    Pancani, T.2    Formentini, L.3    Mascagni, P.4    Fossati, G.5    Leoni, F.6    Moroni, F.7    Chiarugi, A.8
  • 83
    • 15944413194 scopus 로고    scopus 로고
    • Reelin glycoprotein: Structure, biology and roles in health and disease
    • Fatemi SH. Reelin glycoprotein: structure, biology and roles in health and disease. Mol Psychiatry 10: 251-257, 2005.
    • (2005) Mol Psychiatry , vol.10 , pp. 251-257
    • Fatemi, S.H.1
  • 84
    • 65349191920 scopus 로고    scopus 로고
    • The neurodevelopmental hypothesis of schizophrenia, revisited
    • Fatemi SH, Folsom TD. The neurodevelopmental hypothesis of schizophrenia, revisited. Schizophr Bull 35: 528-548, 2009.
    • (2009) Schizophr Bull , vol.35 , pp. 528-548
    • Fatemi, S.H.1    Folsom, T.D.2
  • 85
    • 70349705449 scopus 로고    scopus 로고
    • Histone acetylation is recruited in consolidation as a molecular feature of stronger memories
    • Federman N, Fustinana MS, Romano A. Histone acetylation is recruited in consolidation as a molecular feature of stronger memories. Learn Mem 16: 600-606, 2009.
    • (2009) Learn Mem , vol.16 , pp. 600-606
    • Federman, N.1    Fustinana, M.S.2    Romano, A.3
  • 86
    • 77950187447 scopus 로고    scopus 로고
    • Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons
    • Feng J, Zhou Y, Campbell SL, Le T, Li E, Sweatt JD, Silva AJ, Fan G. Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat Neurosci 13: 423-430, 2010.
    • (2010) Nat Neurosci , vol.13 , pp. 423-430
    • Feng, J.1    Zhou, Y.2    Campbell, S.L.3    Le, T.4    Li, E.5    Sweatt, J.D.6    Silva, A.J.7    Fan, G.8
  • 87
    • 52049126390 scopus 로고    scopus 로고
    • Estradiol-induced enhancement of object memory consolidation involves hippocampal extracellular signal-regulated kinase activation and membrane-bound estrogen receptors
    • Fernandez SM, Lewis MC, Pechenino AS, Harburger LL, Orr PT, Gresack JE, Schafe GE, Frick KM. Estradiol-induced enhancement of object memory consolidation involves hippocampal extracellular signal-regulated kinase activation and membrane-bound estrogen receptors. J Neurosci 28: 8660-8667, 2008.
    • (2008) J Neurosci , vol.28 , pp. 8660-8667
    • Fernandez, S.M.1    Lewis, M.C.2    Pechenino, A.S.3    Harburger, L.L.4    Orr, P.T.5    Gresack, J.E.6    Schafe, G.E.7    Frick, K.M.8
  • 91
    • 28744449248 scopus 로고    scopus 로고
    • Opposing roles of transient and prolonged expression of p25 in synaptic plasticity and hippocampus-dependent memory
    • Fischer A, Sananbenesi F, Pang PT, Lu B, Tsai LH. Opposing roles of transient and prolonged expression of p25 in synaptic plasticity and hippocampus-dependent memory. Neuron 48: 825-838, 2005.
    • (2005) Neuron , vol.48 , pp. 825-838
    • Fischer, A.1    Sananbenesi, F.2    Pang, P.T.3    Lu, B.4    Tsai, L.H.5
  • 92
    • 34248523169 scopus 로고    scopus 로고
    • Recovery of learning and memory is associated with chromatin remodelling
    • Fischer A, Sananbenesi F, Wang XY, Dobbin M, Tsai LH. Recovery of learning and memory is associated with chromatin remodelling. Nature 447: 172-178, 2007.
    • (2007) Nature , vol.447 , pp. 172-178
    • Fischer, A.1    Sananbenesi, F.2    Wang, X.Y.3    Dobbin, M.4    Tsai, L.H.5
  • 93
    • 0033527727 scopus 로고    scopus 로고
    • Nongenomic transmission across generations of maternal behavior and stress responses in the rat
    • Francis D, Diorio J, Liu D, Meaney MJ. Nongenomic transmission across generations of maternal behavior and stress responses in the rat. Science 286: 1155-1158, 1999.
    • (1999) Science , vol.286 , pp. 1155-1158
    • Francis, D.1    Diorio, J.2    Liu, D.3    Meaney, M.J.4
  • 96
    • 0025923293 scopus 로고
    • The effect of dopaminergic D1 receptor blockade during tetanization on the expression of long-term potentiation in the rat CA1 region in vitro
    • Frey U, Matthies H, Reymann KG, Matthies H. The effect of dopaminergic D1 receptor blockade during tetanization on the expression of long-term potentiation in the rat CA1 region in vitro. Neurosci Lett 129: 111-114, 1991.
    • (1991) Neurosci Lett , vol.129 , pp. 111-114
    • Frey, U.1    Matthies, H.2    Reymann, K.G.3    Matthies, H.4
  • 97
    • 61949313909 scopus 로고    scopus 로고
    • Single immobilization stress differentially alters the expression profi{ligature}le of transcripts of the brain-derived neurotrophic factor (BDNF) gene and histone acetylation at its promoters in the rat hippocampus
    • Fuchikami M, Morinobu S, Kurata A, Yamamoto S, Yamawaki S. Single immobilization stress differentially alters the expression profi{ligature}le of transcripts of the brain-derived neurotrophic factor (BDNF) gene and histone acetylation at its promoters in the rat hippocampus. Int J Neuropsychopharmacol 12: 73-82, 2009.
    • (2009) Int J Neuropsychopharmacol , vol.12 , pp. 73-82
    • Fuchikami, M.1    Morinobu, S.2    Kurata, A.3    Yamamoto, S.4    Yamawaki, S.5
  • 98
    • 0034795827 scopus 로고    scopus 로고
    • Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain
    • Fukumoto T, Morinobu S, Okamoto Y, Kagaya A, Yamawaki S. Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain. Psychopharmacology 158: 100-106, 2001.
    • (2001) Psychopharmacology , vol.158 , pp. 100-106
    • Fukumoto, T.1    Morinobu, S.2    Okamoto, Y.3    Kagaya, A.4    Yamawaki, S.5
  • 99
    • 10644237168 scopus 로고    scopus 로고
    • S-adenosylmethionine/homocysteine cycle alterations modify DNA methylation status with consequent deregulation of PS1 and BACE and beta-amyloid production
    • Fuso A, Seminara L, Cavallaro RA, D'Anselmi F, Scarpa S. S-adenosylmethionine/homocysteine cycle alterations modify DNA methylation status with consequent deregulation of PS1 and BACE and beta-amyloid production. Mol Cell Neurosci 28: 195-204, 2005.
    • (2005) Mol Cell Neurosci , vol.28 , pp. 195-204
    • Fuso, A.1    Seminara, L.2    Cavallaro, R.A.3    D'anselmi, F.4    Scarpa, S.5
  • 100
    • 0034712047 scopus 로고    scopus 로고
    • Mammalian neural stem cells
    • Gage FH. Mammalian neural stem cells. Science 287: 1433-1438, 2000.
    • (2000) Science , vol.287 , pp. 1433-1438
    • Gage, F.H.1
  • 103
    • 69249203574 scopus 로고    scopus 로고
    • SUMO association with repressor complexes, emerging routes for transcriptional control
    • Garcia-Dominguez M, Reyes JC. SUMO association with repressor complexes, emerging routes for transcriptional control. Biochim Biophys Acta 1789: 451-459, 2009.
    • (2009) Biochim Biophys Acta , vol.1789 , pp. 451-459
    • Garcia-Dominguez, M.1    Reyes, J.C.2
  • 105
    • 77955709610 scopus 로고    scopus 로고
    • HDAC inhibition promotes neuronal outgrowth and counteracts growth cone collapse through CBP/p300. and P/CAF-dependent p53 acetylation
    • Gaub P, Tedeschi A, Puttagunta R, Nguyen T, Schmandke A, Di Giovanni S. HDAC inhibition promotes neuronal outgrowth and counteracts growth cone collapse through CBP/p300. and P/CAF-dependent p53 acetylation. Cell Death Differ 17: 1392-1408, 2010.
    • (2010) Cell Death Differ , vol.17 , pp. 1392-1408
    • Gaub, P.1    Tedeschi, A.2    Puttagunta, R.3    Nguyen, T.4    Schmandke, A.5    Di Giovanni, S.6
  • 107
    • 0030137717 scopus 로고    scopus 로고
    • Identifi{ligature}cation of the gene FMR2, associated with FRAXE mental retardation
    • Gecz J, Gedeon AK, Sutherland GR, Mulley JC. Identifi{ligature}cation of the gene FMR2, associated with FRAXE mental retardation. Nat Genet 13: 105-108, 1996.
    • (1996) Nat Genet , vol.13 , pp. 105-108
    • Gecz, J.1    Gedeon, A.K.2    Sutherland, G.R.3    Mulley, J.C.4
  • 109
    • 33847398443 scopus 로고    scopus 로고
    • Alpha thalassaemia-mental retardation, X linked
    • Gibbons R. Alpha thalassaemia-mental retardation, X linked. Orphanet J Rare Dis 1: 15, 2006.
    • (2006) Orphanet J Rare Dis , vol.1 , pp. 15
    • Gibbons, R.1
  • 110
    • 0034069652 scopus 로고    scopus 로고
    • Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation
    • Gibbons RJ, McDowell TL, Raman S, O'Rourke DM, Garrick D, Ayyub H, Higgs DR. Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation. Nat Genet 24: 368-371, 2000.
    • (2000) Nat Genet , vol.24 , pp. 368-371
    • Gibbons, R.J.1    McDowell, T.L.2    Raman, S.3    O'Rourke, D.M.4    Garrick, D.5    Ayyub, H.6    Higgs, D.R.7
  • 112
    • 3042576479 scopus 로고    scopus 로고
    • Valproic acid: An old drug newly discovered as inhibitor of histone deacetylases
    • Gottlicher M. Valproic acid: an old drug newly discovered as inhibitor of histone deacetylases. Ann Hematol 83 Suppl 1: S91-S92, 2004.
    • (2004) Ann Hematol , vol.83 , Issue.SUPPL. 1
    • Gottlicher, M.1
  • 113
    • 44649134044 scopus 로고    scopus 로고
    • Epigenetic codes in cognition and behaviour
    • Gräff J, Mansuy IM. Epigenetic codes in cognition and behaviour. Behav Brain Res 192: 70-87, 2008.
    • (2008) Behav Brain Res , vol.192 , pp. 70-87
    • Gräff, J.1    Mansuy, I.M.2
  • 114
    • 34547503309 scopus 로고    scopus 로고
    • Dynamic BDNF activity in nucleus accumbens with cocaine use increases self-administration and relapse
    • Graham DL, Edwards S, Bachtell RK, DiLeone RJ, Rios M, Self DW. Dynamic BDNF activity in nucleus accumbens with cocaine use increases self-administration and relapse. Nat Neurosci 10: 1029-1037, 2007.
    • (2007) Nat Neurosci , vol.10 , pp. 1029-1037
    • Graham, D.L.1    Edwards, S.2    Bachtell, R.K.3    Dileone, R.J.4    Rios, M.5    Self, D.W.6
  • 116
    • 0035032345 scopus 로고    scopus 로고
    • A tale of histone modifi{ligature}cations
    • Grant PA. A tale of histone modifi{ligature}cations. Genome Biol 2: 3, 2001.
    • (2001) Genome Biol , vol.2 , pp. 3
    • Grant, P.A.1
  • 117
    • 77955285002 scopus 로고    scopus 로고
    • Sex-specifi{ligature}c parent-of-origin allelic expression in the mouse brain
    • Gregg C, Zhang J, Butler JE, Haig D, Dulac C. Sex-specifi{ligature}c parent-of-origin allelic expression in the mouse brain. Science 329: 682-685, 2010.
    • (2010) Science , vol.329 , pp. 682-685
    • Gregg, C.1    Zhang, J.2    Butler, J.E.3    Haig, D.4    Dulac, C.5
  • 118
    • 77955299096 scopus 로고    scopus 로고
    • High-resolution analysis of parent-of-origin allelic expression in the mouse brain
    • Gregg C, Zhang J, Weissbourd B, Luo S, Schroth GP, Haig D, Dulac C. High-resolution analysis of parent-of-origin allelic expression in the mouse brain. Science 329: 643-648, 2010.
    • (2010) Science , vol.329 , pp. 643-648
    • Gregg, C.1    Zhang, J.2    Weissbourd, B.3    Luo, S.4    Schroth, G.P.5    Haig, D.6    Dulac, C.7
  • 119
    • 0037321303 scopus 로고    scopus 로고
    • Time-dependent increases in brain-derived neurotrophic factor protein levels within the mesolimbic dopamine system after withdrawal from cocaine: Implications for incubation of cocaine craving
    • Grimm JW, Lu L, Hayashi T, Hope BT, Su TP, Shaham Y. Time-dependent increases in brain-derived neurotrophic factor protein levels within the mesolimbic dopamine system after withdrawal from cocaine: implications for incubation of cocaine craving. J Neurosci 23: 742-747, 2003.
    • (2003) J Neurosci , vol.23 , pp. 742-747
    • Grimm, J.W.1    Lu, L.2    Hayashi, T.3    Hope, B.T.4    Su, T.P.5    Shaham, Y.6
  • 120
    • 0030138905 scopus 로고    scopus 로고
    • Identifi{ligature}cation of FMR2, a novel gene associated with the FRAXE CCG repeat and CpG island
    • Gu Y, Shen Y, Gibbs RA, Nelson DL. Identifi{ligature}cation of FMR2, a novel gene associated with the FRAXE CCG repeat and CpG island. Nat Genet 13: 109-113, 1996.
    • (1996) Nat Genet , vol.13 , pp. 109-113
    • Gu, Y.1    Shen, Y.2    Gibbs, R.A.3    Nelson, D.L.4
  • 122
    • 0037111980 scopus 로고    scopus 로고
    • Integration of long-term-memory-related synaptic plasticity involves bidirectional regulation of gene expression and chromatin structure
    • Guan ZH, Giustetto M, Lomvardas S, Kim JH, Miniaci MC, Schwartz JH, Thanos D, Kandel ER. Integration of long-term-memory-related synaptic plasticity involves bidirectional regulation of gene expression and chromatin structure. Cell 111: 483-493, 2002.
    • (2002) Cell , vol.111 , pp. 483-493
    • Guan, Z.H.1    Giustetto, M.2    Lomvardas, S.3    Kim, J.H.4    Miniaci, M.C.5    Schwartz, J.H.6    Thanos, D.7    Kandel, E.R.8
  • 125
    • 67349243029 scopus 로고    scopus 로고
    • Effects of the histone deacetylase inhibitor sodium butyrate in models of depression and anxiety
    • Gundersen BB, Blendy JA. Effects of the histone deacetylase inhibitor sodium butyrate in models of depression and anxiety. Neuropharmacology 57: 67-74, 2009.
    • (2009) Neuropharmacology , vol.57 , pp. 67-74
    • Gundersen, B.B.1    Blendy, J.A.2
  • 127
    • 0035094767 scopus 로고    scopus 로고
    • A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
    • Guy J, Hendrich B, Holmes M, Martin JE, Bird A. A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome. Nat Genet 27: 322-326, 2001.
    • (2001) Nat Genet , vol.27 , pp. 322-326
    • Guy, J.1    Hendrich, B.2    Holmes, M.3    Martin, J.E.4    Bird, A.5
  • 128
    • 57749170458 scopus 로고    scopus 로고
    • The many roles of histone deacetylases in development and physiology: Implications for disease and therapy
    • Haberland M, Montgomery RL, Olson EN. The many roles of histone deacetylases in development and physiology: implications for disease and therapy. Nat Rev Genet 10: 32-42, 2009.
    • (2009) Nat Rev Genet , vol.10 , pp. 32-42
    • Haberland, M.1    Montgomery, R.L.2    Olson, E.N.3
  • 129
  • 130
    • 52649177210 scopus 로고    scopus 로고
    • Astrocyte-specifi{ligature}c genes are generally demethylated in neural precursor cells prior to astrocytic differentiation
    • Hatada I, Namihira M, Morita S, Kimura M, Horii T, Nakashima K. Astrocyte-specifi{ligature}c genes are generally demethylated in neural precursor cells prior to astrocytic differentiation. PLoS One 3: e3189, 2008.
    • (2008) PLoS One , vol.e3189 , pp. 3
    • Hatada, I.1    Namihira, M.2    Morita, S.3    Kimura, M.4    Horii, T.5    Nakashima, K.6
  • 131
    • 42649140229 scopus 로고    scopus 로고
    • Events at the transition between cell cycle exit and oligodendrocyte progenitor differentiation: The role of HDAC and YY1
    • He Y, Sandoval J, Casaccia-Bonnefil P. Events at the transition between cell cycle exit and oligodendrocyte progenitor differentiation: the role of HDAC and YY1. Neuron Glia Biol 3: 221-231, 2007.
    • (2007) Neuron Glia Biol , vol.3 , pp. 221-231
    • He, Y.1    Sandoval, J.2    Casaccia-Bonnefil, P.3
  • 136
    • 38649094308 scopus 로고    scopus 로고
    • GAD1 mRNA expression and DNA methylation in prefrontal cortex of subjects with schizophrenia
    • Huang HS, Akbarian S. GAD1 mRNA expression and DNA methylation in prefrontal cortex of subjects with schizophrenia. PLoS ONE 2: e809, 2007.
    • (2007) PLoS ONE , vol.e809 , pp. 2
    • Huang, H.S.1    Akbarian, S.2
  • 137
    • 78650516828 scopus 로고    scopus 로고
    • Urocortin modulates dopaminergic neuronal survival via inhibition of glycogen synthase kinase-3beta and histone deacetylase
    • Huang HY, Lin SZ, Chen WF, Li KW, Kuo JS, Wang MJ. Urocortin modulates dopaminergic neuronal survival via inhibition of glycogen synthase kinase-3beta and histone deacetylase. Neurobiol Aging 2009.
    • (2009) Neurobiol Aging
    • Huang, H.Y.1    Lin, S.Z.2    Chen, W.F.3    Li, K.W.4    Kuo, J.S.5    Wang, M.J.6
  • 138
    • 0036812485 scopus 로고    scopus 로고
    • Altered histone acetylation at glutamate receptor 2 and brain-derived neurotrophic factor genes is an early event triggered by status epilepticus
    • Huang Y, Doherty JJ, Dingledine R. Altered histone acetylation at glutamate receptor 2 and brain-derived neurotrophic factor genes is an early event triggered by status epilepticus. J Neurosci 22: 8422-8428, 2002.
    • (2002) J Neurosci , vol.22 , pp. 8422-8428
    • Huang, Y.1    Doherty, J.J.2    Dingledine, R.3
  • 139
    • 0033306577 scopus 로고    scopus 로고
    • Transcriptional repression by REST: Recruitment of Sin3A and histone deacetylase to neuronal genes
    • Huang Y, Myers SJ, Dingledine R. Transcriptional repression by REST: recruitment of Sin3A and histone deacetylase to neuronal genes. Nat Neurosci 2: 867-872, 1999.
    • (1999) Nat Neurosci , vol.2 , pp. 867-872
    • Huang, Y.1    Myers, S.J.2    Dingledine, R.3
  • 140
    • 0027205597 scopus 로고
    • Heightened synaptic plasticity of hippocampal CA1 neurons during a cholinergically induced rhythmic state
    • Huerta PT, Lisman JE. Heightened synaptic plasticity of hippocampal CA1 neurons during a cholinergically induced rhythmic state. Nature 364: 723-725, 1993.
    • (1993) Nature , vol.364 , pp. 723-725
    • Huerta, P.T.1    Lisman, J.E.2
  • 142
    • 1842455106 scopus 로고    scopus 로고
    • Regulation of microglial infl{ligature}ammatory response by sodium butyrate and short-chain fatty acids
    • Huuskonen J, Suuronen T, Nuutinen T, Kyrylenko S, Salminen A. Regulation of microglial infl{ligature}ammatory response by sodium butyrate and short-chain fatty acids. Br J Pharmacol 141: 874-880, 2004.
    • (2004) Br J Pharmacol , vol.141 , pp. 874-880
    • Huuskonen, J.1    Suuronen, T.2    Nuutinen, T.3    Kyrylenko, S.4    Salminen, A.5
  • 143
    • 77449158988 scopus 로고    scopus 로고
    • Epigenetic programming of mu opioid receptor gene in mouse brain is regulated by MeCP2 and Brg1 chromatin remodeling factor
    • Hwang CK, Song KY, Kim CS, Choi HS, Guo XH, Law PY, Wei LN, Loh HH. Epigenetic programming of mu opioid receptor gene in mouse brain is regulated by MeCP2 and Brg1 chromatin remodeling factor. J Cell Mol Med 13: 3591-3615, 2009.
    • (2009) J Cell Mol Med , vol.13 , pp. 3591-3615
    • Hwang, C.K.1    Song, K.Y.2    Kim, C.S.3    Choi, H.S.4    Guo, X.H.5    Law, P.Y.6    Wei, L.N.7    Loh, H.H.8
  • 144
    • 77956141295 scopus 로고    scopus 로고
    • MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212
    • Im HI, Hollander JA, Bali P, Kenny PJ. MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212. Nat Neurosci 13: 1120-1127, 2010.
    • (2010) Nat Neurosci , vol.13 , pp. 1120-1127
    • Im, H.I.1    Hollander, J.A.2    Bali, P.3    Kenny, P.J.4
  • 146
    • 20044389866 scopus 로고    scopus 로고
    • DNA methylation status of SOX10 correlates with its downregulation and oligodendrocyte dysfunction in schizophrenia
    • Iwamoto K, Bundo M, Yamada K, Takao H, Iwayama-Shigeno Y, Yoshikawa T, Kato T. DNA methylation status of SOX10 correlates with its downregulation and oligodendrocyte dysfunction in schizophrenia. J Neurosci 25: 5376-5381, 2005.
    • (2005) J Neurosci , vol.25 , pp. 5376-5381
    • Iwamoto, K.1    Bundo, M.2    Yamada, K.3    Takao, H.4    Iwayama-Shigeno, Y.5    Yoshikawa, T.6    Kato, T.7
  • 147
    • 0037372003 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
    • Jaenisch R, Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nature Genet 33: 245-254, 2003.
    • (2003) Nature Genet , vol.33 , pp. 245-254
    • Jaenisch, R.1    Bird, A.2
  • 150
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein T, Allis CD. Translating the histone code. Science 293: 1074-1080, 2001.
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 152
    • 0033816348 scopus 로고    scopus 로고
    • Costs in the treatment of parkinsonism
    • Jost WH. Costs in the treatment of parkinsonism. J Neurol 247. Suppl 4: 31-33, 2000.
    • (2000) J Neurol , vol.247 , Issue.SUPPL. 4 , pp. 31-33
    • Jost, W.H.1
  • 153
    • 0035798238 scopus 로고    scopus 로고
    • The molecular biology of memory storage: A dialogue between genes and synapses
    • Kandel ER. The molecular biology of memory storage: a dialogue between genes and synapses. Science 294: 1030-1038, 2001.
    • (2001) Science , vol.294 , pp. 1030-1038
    • Kandel, E.R.1
  • 155
    • 0037087576 scopus 로고    scopus 로고
    • Dynamics of global histone acetylation and deacetylation in vivo: Rapid restoration of normal his-tone acetylation status upon removal of activators and repressors
    • Katan-Khaykovich Y, Struhl K. Dynamics of global histone acetylation and deacetylation in vivo: rapid restoration of normal his-tone acetylation status upon removal of activators and repressors. Genes Dev 16: 743-752, 2002.
    • (2002) Genes Dev , vol.16 , pp. 743-752
    • Katan-Khaykovich, Y.1    Struhl, K.2
  • 156
    • 53249130741 scopus 로고    scopus 로고
    • Therapeutic application of his-tone deacetylase inhibitors for central ervous system disorders
    • Kazantsev AG, Thompson LM. Therapeutic application of his-tone deacetylase inhibitors for central ervous system disorders. Nat Rev Drug Discov 7: 854-868, 2008.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 854-868
    • Kazantsev, A.G.1    Thompson, L.M.2
  • 157
  • 158
    • 76749091005 scopus 로고    scopus 로고
    • Inhibitors of class 1 histone deacety-lases reverse contextual memory defi{ligature}cits in a mouse model of Alzheimer's disease
    • Kilgore M, Miller CA, Fass DM, Hennig KM, Haggarty SJ, Sweatt JD, Rumbaugh G. Inhibitors of class 1 histone deacety-lases reverse contextual memory defi{ligature}cits in a mouse model of Alzheimer's disease. Neuropsychopharmacology 35: 853-854, 2010.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 853-854
    • Kilgore, M.1    Miller, C.A.2    Fass, D.M.3    Hennig, K.M.4    Haggarty, S.J.5    Sweatt, J.D.6    Rumbaugh, G.7
  • 161
    • 67651146826 scopus 로고    scopus 로고
    • The HDAC inhibitor, sodium butyrate, stimulates neurogenesis in the ischemic brain
    • Kim HJ, Leeds P, Chuang DM. The HDAC inhibitor, sodium butyrate, stimulates neurogenesis in the ischemic brain. J Neurochem 110: 1226-1240, 2009.
    • (2009) J Neurochem , vol.110 , pp. 1226-1240
    • Kim, H.J.1    Leeds, P.2    Chuang, D.M.3
  • 162
    • 34248530339 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors exhibit anti-infl{ligature}ammatory and neuroprotective effects in a rat permanent ischemic model of stroke: Multiple mechanisms of action
    • Kim HJ, Rowe M, Ren M, Hong JS, Chen PS, Chuang DM. Histone deacetylase inhibitors exhibit anti-infl{ligature}ammatory and neuroprotective effects in a rat permanent ischemic model of stroke: multiple mechanisms of action. J Pharmacol Exp Ther 321: 892-901, 2007.
    • (2007) J Pharmacol Exp Ther , vol.321 , pp. 892-901
    • Kim, H.J.1    Rowe, M.2    Ren, M.3    Hong, J.S.4    Chen, P.S.5    Chuang, D.M.6
  • 163
    • 9144234107 scopus 로고    scopus 로고
    • Inhibition of histone deacetylation enhances the neurotoxicity induced by the C-terminal fragments of amyloid precursor protein
    • Kim HS, Kim EM, Kim NJ, Chang KA, Choi Y, Ahn KW, Lee JH, Kim S, Park CH, Suh YH. Inhibition of histone deacetylation enhances the neurotoxicity induced by the C-terminal fragments of amyloid precursor protein. J Neurosci Res 75: 117-124, 2004.
    • (2004) J Neurosci Res , vol.75 , pp. 117-124
    • Kim, H.S.1    Kim, E.M.2    Kim, N.J.3    Chang, K.A.4    Choi, Y.5    Ahn, K.W.6    Lee, J.H.7    Kim, S.8    Park, C.H.9    Suh, Y.H.10
  • 164
    • 38349159260 scopus 로고    scopus 로고
    • In vivo YY1 knockdown effects on genomic imprinting
    • Kim J, Kim JD. In vivo YY1 knockdown effects on genomic imprinting. Hum Mol Genet 17: 391-401, 2008.
    • (2008) Hum Mol Genet , vol.17 , pp. 391-401
    • Kim, J.1    Kim, J.D.2
  • 165
    • 33644978395 scopus 로고    scopus 로고
    • Acute in vivo effect of ethanol (binge drinking) on histone H3 modifi{ligature}cations in rat tissues
    • Kim JS, Shukla SD. Acute in vivo effect of ethanol (binge drinking) on histone H3 modifi{ligature}cations in rat tissues. Alcohol Alcohol 41: 126-132, 2006.
    • (2006) Alcohol Alcohol , vol.41 , pp. 126-132
    • Kim, J.S.1    Shukla, S.D.2
  • 166
    • 34248222814 scopus 로고    scopus 로고
    • Developmental regulation of Eed complex composition governs a switch in global histone modifi{ligature}cation in brain
    • Kim SY, Levenson JM, Korsmeyer S, Sweatt JD, Schumacher A. Developmental regulation of Eed complex composition governs a switch in global histone modifi{ligature}cation in brain. J Biol Chem 282: 9962-9972, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 9962-9972
    • Kim, S.Y.1    Levenson, J.M.2    Korsmeyer, S.3    Sweatt, J.D.4    Schumacher, A.5
  • 167
    • 32344450824 scopus 로고    scopus 로고
    • Genomic DNA methylation: The mark and its mediators
    • Klose RJ, Bird AP. Genomic DNA methylation: the mark and its mediators. Trends Biochem Sci 31: 89-97, 2006.
    • (2006) Trends Biochem Sci , vol.31 , pp. 89-97
    • Klose, R.J.1    Bird, A.P.2
  • 168
    • 33947513027 scopus 로고    scopus 로고
    • Regulation of histone methylation by demethylimination and demethylation
    • Klose RJ, Zhang Y. Regulation of histone methylation by demethylimination and demethylation. Nat Rev Mol Cell Biol 8: 307-318, 2007.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 307-318
    • Klose, R.J.1    Zhang, Y.2
  • 169
    • 33749583553 scopus 로고    scopus 로고
    • Alpha-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity
    • Kontopoulos E, Parvin JD, Feany MB. Alpha-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity. Hum Mol Genet 15: 3012-3023, 2006.
    • (2006) Hum Mol Genet , vol.15 , pp. 3012-3023
    • Kontopoulos, E.1    Parvin, J.D.2    Feany, M.B.3
  • 170
    • 2942731425 scopus 로고    scopus 로고
    • CBP histone acetyltransferase activity is a critical component of memory consolidation
    • Korzus E, Rosenfeld MG, Mayford M. CBP histone acetyltransferase activity is a critical component of memory consolidation. Neuron 42: 961-972, 2004.
    • (2004) Neuron , vol.42 , pp. 961-972
    • Korzus, E.1    Rosenfeld, M.G.2    Mayford, M.3
  • 172
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifi{ligature}cations and their function
    • Kouzarides T. Chromatin modifi{ligature}cations and their function. Cell 128: 693-705, 2007.
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 173
    • 66149123748 scopus 로고    scopus 로고
    • The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
    • Kriaucionis S, Heintz N. The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 324: 929-930, 2009.
    • (2009) Science , vol.324 , pp. 929-930
    • Kriaucionis, S.1    Heintz, N.2
  • 174
    • 65549132937 scopus 로고    scopus 로고
    • Neuronal differentiation is regulated by leucine-rich acidic nuclear protein (LANP), a member of the inhibitor of histone acetyltransferase complex
    • Kular RK, Cvetanovic M, Siferd S, Kini AR, Opal P. Neuronal differentiation is regulated by leucine-rich acidic nuclear protein (LANP), a member of the inhibitor of histone acetyltransferase complex. J Biol Chem 284: 7783-7792, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 7783-7792
    • Kular, R.K.1    Cvetanovic, M.2    Siferd, S.3    Kini, A.R.4    Opal, P.5
  • 176
    • 59449101948 scopus 로고    scopus 로고
    • The reelin and GAD67 promoters are activated by epigenetic drugs that facilitate the disruption of local repressor complexes
    • Kundakovic M, Chen Y, Guidotti A, Grayson DR. The reelin and GAD67 promoters are activated by epigenetic drugs that facilitate the disruption of local repressor complexes. Mol Pharmacol 75: 342-354, 2009.
    • (2009) Mol Pharmacol , vol.75 , pp. 342-354
    • Kundakovic, M.1    Chen, Y.2    Guidotti, A.3    Grayson, D.R.4
  • 177
    • 0038576158 scopus 로고    scopus 로고
    • The power and the promise of DNA methylation markers
    • Laird PW. The power and the promise of DNA methylation markers. Nature Rev Cancer 3: 253-266, 2003.
    • (2003) Nature Rev Cancer , vol.3 , pp. 253-266
    • Laird, P.W.1
  • 178
    • 38149116286 scopus 로고    scopus 로고
    • Pulse inhibition of histone deacetylases induces complete resistance to oxidative death in cortical neurons without toxicity and reveals a role for cytoplasmic p21(waf1/cip1) in cell cycle-independent neuroprotection
    • Langley B, D'Annibale MA, Suh K, Ayoub I, Tolhurst A, Bastan B, Yang L, Ko B, Fisher M, Cho S, Beal MF, Ratan RR. Pulse inhibition of histone deacetylases induces complete resistance to oxidative death in cortical neurons without toxicity and reveals a role for cytoplasmic p21(waf1/cip1) in cell cycle-independent neuroprotection. J Neurosci 28: 163-176, 2008.
    • (2008) J Neurosci , vol.28 , pp. 163-176
    • Langley, B.1    D'annibale, M.A.2    Suh, K.3    Ayoub, I.4    Tolhurst, A.5    Bastan, B.6    Yang, L.7    Ko, B.8    Fisher, M.9    Cho, S.10    Beal, M.F.11    Ratan, R.R.12
  • 180
    • 64449086698 scopus 로고    scopus 로고
    • BDNF overexpression in hippocampal neurons prevents dendritic atrophy caused by Rett-associated MECP2 mutations
    • Larimore JL, Chapleau CA, Kudo S, Theibert A, Percy AK, Pozzo-Miller L. BDNF overexpression in hippocampal neurons prevents dendritic atrophy caused by Rett-associated MECP2 mutations. Neurobiol Dis 34: 199-211, 2009.
    • (2009) Neurobiol Dis , vol.34 , pp. 199-211
    • Larimore, J.L.1    Chapleau, C.A.2    Kudo, S.3    Theibert, A.4    Percy, A.K.5    Pozzo-Miller, L.6
  • 181
    • 35848936709 scopus 로고    scopus 로고
    • Dent SY. Cross-regulation of histone modifi{ligature}cations
    • Latham JA, Dent SY. Cross-regulation of histone modifi{ligature}cations. Nat Struct Mol Biol 14: 1017-1024, 2007.
    • (2007) Nat Struct Mol Biol , vol.14 , pp. 1017-1024
    • Latham, J.A.1
  • 182
    • 35748972690 scopus 로고    scopus 로고
    • Systemic or intrahippocampal delivery of histone deacetylase inhibitors facilitates fear extinction
    • Lattal KM, Barrett RM, Wood MA. Systemic or intrahippocampal delivery of histone deacetylase inhibitors facilitates fear extinction. Behav Neurosci 121: 1125-1131, 2007.
    • (2007) Behav Neurosci , vol.121 , pp. 1125-1131
    • Lattal, K.M.1    Barrett, R.M.2    Wood, M.A.3
  • 184
    • 33745187327 scopus 로고    scopus 로고
    • Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medications
    • Lee MG, Wynder C, Schmidt DM, McCafferty DG, Shiekhattar R. Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medications. Chem Biol 13: 563-567, 2006.
    • (2006) Chem Biol , vol.13 , pp. 563-567
    • Lee, M.G.1    Wynder, C.2    Schmidt, D.M.3    McCafferty, D.G.4    Shiekhattar, R.5
  • 185
    • 33746065340 scopus 로고    scopus 로고
    • Endogenous alpha-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity
    • Leng Y, Chuang DM. Endogenous alpha-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity. J Neurosci 26: 7502-7512, 2006.
    • (2006) J Neurosci , vol.26 , pp. 7502-7512
    • Leng, Y.1    Chuang, D.M.2
  • 186
    • 40449135649 scopus 로고    scopus 로고
    • Synergistic neuroprotective effects of lithium and valproic acid or other histone deacetylase inhibitors in neurons: Roles of glycogen synthase kinase-3 inhibition
    • Leng Y, Liang MH, Ren M, Marinova Z, Leeds P, Chuang DM. Synergistic neuroprotective effects of lithium and valproic acid or other histone deacetylase inhibitors in neurons: roles of glycogen synthase kinase-3 inhibition. J Neurosci 28: 2576-2588, 2008.
    • (2008) J Neurosci , vol.28 , pp. 2576-2588
    • Leng, Y.1    Liang, M.H.2    Ren, M.3    Marinova, Z.4    Leeds, P.5    Chuang, D.M.6
  • 189
    • 13244276460 scopus 로고    scopus 로고
    • Epigenetic mechanisms in memory formation
    • Levenson JM, Sweatt JD. Epigenetic mechanisms in memory formation. Nat Rev Neurosci 6: 108-118, 2005.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 108-118
    • Levenson, J.M.1    Sweatt, J.D.2
  • 190
    • 33744466559 scopus 로고    scopus 로고
    • Epigenetic mechanisms: A common theme in vertebrate and invertebrate memory formation
    • Levenson JM, Sweatt JD. Epigenetic mechanisms: a common theme in vertebrate and invertebrate memory formation. Cell Mol Life Sci 63: 1009-1016, 2006.
    • (2006) Cell Mol Life Sci , vol.63 , pp. 1009-1016
    • Levenson, J.M.1    Sweatt, J.D.2
  • 191
    • 30044435060 scopus 로고    scopus 로고
    • CREB-binding protein controls response to cocaine by acetylating histones at the fosB promoter in the mouse striatum
    • Levine AA, Guan Z, Barco A, Xu S, Kandel ER, Schwartz JH. CREB-binding protein controls response to cocaine by acetylating histones at the fosB promoter in the mouse striatum. Proc Natl Acad Sci USA 102: 19186-19191, 2005.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 19186-19191
    • Levine, A.A.1    Guan, Z.2    Barco, A.3    Xu, S.4    Kandel, E.R.5    Schwartz, J.H.6
  • 192
    • 33847070442 scopus 로고    scopus 로고
    • The role of chromatin during transcription
    • Li B, Carey M, Workman JL. The role of chromatin during transcription. Cell 128: 707-719, 2007.
    • (2007) Cell , vol.128 , pp. 707-719
    • Li, B.1    Carey, M.2    Workman, J.L.3
  • 193
    • 0036733675 scopus 로고    scopus 로고
    • Chromatin modifi{ligature}cation and epigenetic reprogramming in mammalian development
    • Li E. Chromatin modifi{ligature}cation and epigenetic reprogramming in mammalian development. Nature Rev Genet 3: 662-673, 2002.
    • (2002) Nature Rev Genet , vol.3 , pp. 662-673
    • Li, E.1
  • 194
    • 4444382918 scopus 로고    scopus 로고
    • Dopamine D2-like antagonists induce chromatin remodeling in striatal neurons through cyclic AMP-protein kinase A and NMDA receptor signaling
    • Li J, Guo Y, Schroeder FA, Youngs RM, Schmidt TW, Ferris C, Konradi C, Akbarian S. Dopamine D2-like antagonists induce chromatin remodeling in striatal neurons through cyclic AMP-protein kinase A and NMDA receptor signaling. J Neurochem 90: 1117-1131, 2004.
    • (2004) J Neurochem , vol.90 , pp. 1117-1131
    • Li, J.1    Guo, Y.2    Schroeder, F.A.3    Youngs, R.M.4    Schmidt, T.W.5    Ferris, C.6    Konradi, C.7    Akbarian, S.8
  • 195
    • 0027405703 scopus 로고
    • Identifi{ligature}cation of a functional silencer element involved in neuron-specifi{ligature}c expression of the synapsin I gene
    • Li L, Suzuki T, Mori N, Greengard P. Identifi{ligature}cation of a functional silencer element involved in neuron-specifi{ligature}c expression of the synapsin I gene. Proc Natl Acad Sci USA 90: 1460-1464, 1993.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1460-1464
    • Li, L.1    Suzuki, T.2    Mori, N.3    Greengard, P.4
  • 198
    • 34447130226 scopus 로고    scopus 로고
    • The glial or neuronal fate choice of oligodendrocyte progenitors is modulated by their ability to acquire an epigenetic memory
    • Liu A, Han YR, Li J, Sun D, Ouyang M, Plummer MR, CasacciaBonnefil P. The glial or neuronal fate choice of oligodendrocyte progenitors is modulated by their ability to acquire an epigenetic memory. J Neurosci 27: 7339-7343, 2007.
    • (2007) J Neurosci , vol.27 , pp. 7339-7343
    • Liu, A.1    Han, Y.R.2    Li, J.3    Sun, D.4    Ouyang, M.5    Plummer, M.R.6    Casacciabonnefil, P.7
  • 200
    • 15444379011 scopus 로고    scopus 로고
    • Regulation of neuron survival and death by p130. and associated chromatin modifi{ligature}ers
    • Liu DX, Nath N, Chellappan SP, Greene LA. Regulation of neuron survival and death by p130. and associated chromatin modifi{ligature}ers. Genes Dev 19: 719-732, 2005.
    • (2005) Genes Dev , vol.19 , pp. 719-732
    • Liu, D.X.1    Nath, N.2    Chellappan, S.P.3    Greene, L.A.4
  • 201
    • 61649089532 scopus 로고    scopus 로고
    • RASSF1A, BLU, NORE1A, PTEN and MGMT expression and promoter methylation in gliomas and glioma cell lines and evidence of deregulated expression of de novo DNMTs
    • Lorente A, Mueller W, Urdangarin E, Lazcoz P, Lass U, von Deimling A, Castresana JS. RASSF1A, BLU, NORE1A, PTEN and MGMT expression and promoter methylation in gliomas and glioma cell lines and evidence of deregulated expression of de novo DNMTs. Brain Pathol 19: 279-292, 2009.
    • (2009) Brain Pathol , vol.19 , pp. 279-292
    • Lorente, A.1    Mueller, W.2    Urdangarin, E.3    Lazcoz, P.4    Lass, U.5    von Deimling, A.6    Castresana, J.S.7
  • 202
    • 33645732219 scopus 로고    scopus 로고
    • Molecular pathology of malignant gliomas
    • Louis DN. Molecular pathology of malignant gliomas. Annu Rev Pathol 1: 97-117, 2006.
    • (2006) Annu Rev Pathol , vol.1 , pp. 97-117
    • Louis, D.N.1
  • 203
    • 0042669998 scopus 로고    scopus 로고
    • Histone phosphorylation: How to proceed
    • Loury R, Sassone-Corsi P. Histone phosphorylation: how to proceed. Methods 31: 40-48, 2003.
    • (2003) Methods , vol.31 , pp. 40-48
    • Loury, R.1    Sassone-Corsi, P.2
  • 205
    • 54849426071 scopus 로고    scopus 로고
    • Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory
    • Lubin FD, Roth TL, Sweatt JD. Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory. J Neurosci 28: 10576-10586, 2008.
    • (2008) J Neurosci , vol.28 , pp. 10576-10586
    • Lubin, F.D.1    Roth, T.L.2    Sweatt, J.D.3
  • 206
    • 34548585044 scopus 로고    scopus 로고
    • The IkappaB kinase regulates chromatin structure during reconsolidation of conditioned fear memories
    • Lubin FD, Sweatt JD. The IkappaB kinase regulates chromatin structure during reconsolidation of conditioned fear memories. Neuron 55: 942-957, 2007.
    • (2007) Neuron , vol.55 , pp. 942-957
    • Lubin, F.D.1    Sweatt, J.D.2
  • 208
    • 1842411320 scopus 로고    scopus 로고
    • Crystal structure of the nucleosome core particle at 2.8 A resolution
    • Luger K, Mader AW, Richmond RK, Sargent DF, Richmond TJ. Crystal structure of the nucleosome core particle at 2.8 A resolution. Nature 389: 251-260, 1997.
    • (1997) Nature , vol.389 , pp. 251-260
    • Luger, K.1    Mader, A.W.2    Richmond, R.K.3    Sargent, D.F.4    Richmond, T.J.5
  • 210
    • 67349157695 scopus 로고    scopus 로고
    • Effects of stress throughout the lifespan on the brain, behaviour and cognition
    • Lupien SJ, McEwen BS, Gunnar MR, Heim C. Effects of stress throughout the lifespan on the brain, behaviour and cognition. Nat Rev Neurosci 10: 434-445, 2009.
    • (2009) Nat Rev Neurosci , vol.10 , pp. 434-445
    • Lupien, S.J.1    McEwen, B.S.2    Gunnar, M.R.3    Heim, C.4
  • 211
  • 212
    • 35448949103 scopus 로고    scopus 로고
    • Inhibition of histone deacetylase activity induces developmental plasticity in oligodendrocyte precursor cells
    • Lyssiotis CA, Walker J, Wu C, Kondo T, Schultz PG, Wu X. Inhibition of histone deacetylase activity induces developmental plasticity in oligodendrocyte precursor cells. Proc Natl Acad Sci USA 104: 14982-14987, 2007.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 14982-14987
    • Lyssiotis, C.A.1    Walker, J.2    Wu, C.3    Kondo, T.4    Schultz, P.G.5    Wu, X.6
  • 215
    • 71349087123 scopus 로고    scopus 로고
    • Modulation of chromatin modifi{ligature}cation facilitates extinction of cocaine-induced conditioned place preference
    • Malvaez M, Sanchis-Segura C, Vo D, Lattal KM, Wood MA. Modulation of chromatin modifi{ligature}cation facilitates extinction of cocaine-induced conditioned place preference. Biol Psychiatry 67: 36-43, 2010.
    • (2010) Biol Psychiatry , vol.67 , pp. 36-43
    • Malvaez, M.1    Sanchis-Segura, C.2    Vo, D.3    Lattal, K.M.4    Wood, M.A.5
  • 216
    • 0141429160 scopus 로고    scopus 로고
    • A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations
    • Marambaud P, Wen PH, Dutt A, Shioi J, Takashima A, Siman R, Robakis NK. A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations. Cell 114: 635-645, 2003.
    • (2003) Cell , vol.114 , pp. 635-645
    • Marambaud, P.1    Wen, P.H.2    Dutt, A.3    Shioi, J.4    Takashima, A.5    Siman, R.6    Robakis, N.K.7
  • 217
    • 0036897351 scopus 로고    scopus 로고
    • Histone deacetylase activity is necessary for oligodendrocyte lineage progression
    • Marin-Husstege M, Muggironi M, Liu A, Casaccia-Bonnefil P. Histone deacetylase activity is necessary for oligodendrocyte lineage progression. J Neurosci 22: 10333-10345, 2002.
    • (2002) J Neurosci , vol.22 , pp. 10333-10345
    • Marin-Husstege, M.1    Muggironi, M.2    Liu, A.3    Casaccia-Bonnefil, P.4
  • 218
    • 70350133780 scopus 로고    scopus 로고
    • Valproic acid induces functional heat-shock protein 70 via Class I histone deacetylase inhibition in cortical neurons: A potential role of Sp1 acetylation
    • Marinova Z, Ren M, Wendland JR, Leng Y, Liang MH, Yasuda S, Leeds P, Chuang DM. Valproic acid induces functional heat-shock protein 70 via Class I histone deacetylase inhibition in cortical neurons: a potential role of Sp1 acetylation. J Neurochem 111: 976-987, 2009.
    • (2009) J Neurochem , vol.111 , pp. 976-987
    • Marinova, Z.1    Ren, M.2    Wendland, J.R.3    Leng, Y.4    Liang, M.H.5    Yasuda, S.6    Leeds, P.7    Chuang, D.M.8
  • 220
    • 0242300612 scopus 로고    scopus 로고
    • DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation
    • Martinowich K, Hattori D, Wu H, Fouse S, He F, Hu Y, Fan G, Sun YE. DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. Science 302: 890-893, 2003.
    • (2003) Science , vol.302 , pp. 890-893
    • Martinowich, K.1    Hattori, D.2    Wu, H.3    Fouse, S.4    He, F.5    Hu, Y.6    Fan, G.7    Sun, Y.E.8
  • 222
    • 10644237968 scopus 로고    scopus 로고
    • RNAi-mediated pathways in the nucleus
    • Matzke MA, Birchler JA. RNAi-mediated pathways in the nucleus. Nat Rev Genet 6: 24-35, 2005.
    • (2005) Nat Rev Genet , vol.6 , pp. 24-35
    • Matzke, M.A.1    Birchler, J.A.2
  • 223
    • 0025273145 scopus 로고
    • Neuron-specifi{ligature}c expression of the rat brain type II sodium channel gene is directed by upstream regulatory elements
    • Maue RA, Kraner SD, Goodman RH, Mandel G. Neuron-specifi{ligature}c expression of the rat brain type II sodium channel gene is directed by upstream regulatory elements. Neuron 4: 223-231, 1990.
    • (1990) Neuron , vol.4 , pp. 223-231
    • Maue, R.A.1    Kraner, S.D.2    Goodman, R.H.3    Mandel, G.4
  • 226
    • 0242384719 scopus 로고    scopus 로고
    • Regulation of gene expression and cocaine reward by CREB and DeltaFosB
    • McClung CA, Nestler EJ. Regulation of gene expression and cocaine reward by CREB and DeltaFosB. Nat Neurosci 6: 1208-1215, 2003.
    • (2003) Nat Neurosci , vol.6 , pp. 1208-1215
    • McClung, C.A.1    Nestler, E.J.2
  • 229
    • 0034928759 scopus 로고    scopus 로고
    • Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations
    • Meaney MJ. Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations. Annu Rev Neurosci 24: 1161-1192, 2001.
    • (2001) Annu Rev Neurosci , vol.24 , pp. 1161-1192
    • Meaney, M.J.1
  • 230
    • 79955640214 scopus 로고    scopus 로고
    • Choline defi{ligature}ciency alters global histone methylation and epigenetic marking at the Re1 site of the calbindin 1 gene
    • Mehedint MG, Niculescu MD, Craciunescu CN, Zeisel SH. Choline defi{ligature}ciency alters global histone methylation and epigenetic marking at the Re1 site of the calbindin 1 gene. FASEB J 2009.
    • (2009) FASEB J
    • Mehedint, M.G.1    Niculescu, M.D.2    Craciunescu, C.N.3    Zeisel, S.H.4
  • 231
    • 33746398550 scopus 로고    scopus 로고
    • Inhibition of histone deacetylation protects wild-type but not gelsolin-defi{ligature}cient neurons from oxygen/ glucose deprivation
    • Meisel A, Harms C, Yildirim F, Bosel J, Kronenberg G, Harms U, Fink KB, Endres M. Inhibition of histone deacetylation protects wild-type but not gelsolin-defi{ligature}cient neurons from oxygen/ glucose deprivation. J Neurochem 98: 1019-1031, 2006.
    • (2006) J Neurochem , vol.98 , pp. 1019-1031
    • Meisel, A.1    Harms, C.2    Yildirim, F.3    Bosel, J.4    Kronenberg, G.5    Harms, U.6    Fink, K.B.7    Endres, M.8
  • 235
    • 41649096261 scopus 로고    scopus 로고
    • DNA methylation and his-tone acetylation work in concert to regulate memory formation and synaptic plasticity
    • Miller CA, Campbell SL, Sweatt JD. DNA methylation and his-tone acetylation work in concert to regulate memory formation and synaptic plasticity. Neurobiol Learn Mem 89: 599-603, 2008.
    • (2008) Neurobiol Learn Mem , vol.89 , pp. 599-603
    • Miller, C.A.1    Campbell, S.L.2    Sweatt, J.D.3
  • 237
    • 33847614418 scopus 로고    scopus 로고
    • Covalent modifi{ligature}cation of DNA regulates memory formation
    • Miller CA, Sweatt JD. Covalent modifi{ligature}cation of DNA regulates memory formation. Neuron 53: 857-869, 2007.
    • (2007) Neuron , vol.53 , pp. 857-869
    • Miller, C.A.1    Sweatt, J.D.2
  • 240
    • 0025958320 scopus 로고
    • Genomic imprinting in mammalian development: A parental tug-of-war
    • Moore T, Haig D. Genomic imprinting in mammalian development: a parental tug-of-war. Trends Genet 7: 45-49, 1991.
    • (1991) Trends Genet , vol.7 , pp. 45-49
    • Moore, T.1    Haig, D.2
  • 241
  • 242
    • 0019957779 scopus 로고
    • Place navigation impaired in rats with hippocampal lesions
    • Morris RG, Garrud P, Rawlins JN, O'Keefe J. Place navigation impaired in rats with hippocampal lesions. Nature 297: 681-683, 1982.
    • (1982) Nature , vol.297 , pp. 681-683
    • Morris, R.G.1    Garrud, P.2    Rawlins, J.N.3    O'Keefe, J.4
  • 244
    • 54049086269 scopus 로고    scopus 로고
    • Sex-specifi{ligature}c programming of offspring emotionality after stress early in pregnancy
    • Mueller BR, Bale TL. Sex-specifi{ligature}c programming of offspring emotionality after stress early in pregnancy. J Neurosci 28: 9055-9065, 2008.
    • (2008) J Neurosci , vol.28 , pp. 9055-9065
    • Mueller, B.R.1    Bale, T.L.2
  • 246
    • 0037303882 scopus 로고    scopus 로고
    • Memory traces unbound
    • Nader K. Memory traces unbound. Trends Neurosci 26: 65-72, 2003.
    • (2003) Trends Neurosci , vol.26 , pp. 65-72
    • Nader, K.1
  • 247
    • 60549091016 scopus 로고    scopus 로고
    • A single standard for memory: The case for reconsolidation
    • Nader K, Hardt O. A single standard for memory: the case for reconsolidation. Nat Rev Neurosci 10: 224-234, 2009.
    • (2009) Nat Rev Neurosci , vol.10 , pp. 224-234
    • Nader, K.1    Hardt, O.2
  • 248
    • 63449086968 scopus 로고    scopus 로고
    • Costello JF. Epigenetic mechanisms in glioblastoma multiforme
    • Nagarajan RP, Costello JF. Epigenetic mechanisms in glioblastoma multiforme. Semin Cancer Biol 19: 188-197, 2009.
    • (2009) Semin Cancer Biol , vol.19 , pp. 188-197
    • Nagarajan, R.P.1
  • 251
    • 0033598827 scopus 로고    scopus 로고
    • Neural restrictive silencer factor recruits mSin3 and histone deacetylase complex to repress neuron-specifi{ligature}c target genes
    • Naruse Y, Aoki T, Kojima T, Mori N. Neural restrictive silencer factor recruits mSin3 and histone deacetylase complex to repress neuron-specifi{ligature}c target genes. Proc Natl Acad Sci USA 96: 13691-13696, 1999.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 13691-13696
    • Naruse, Y.1    Aoki, T.2    Kojima, T.3    Mori, N.4
  • 253
    • 38349044361 scopus 로고    scopus 로고
    • Activity-dependent suppression of miniature neurotransmission through the regulation of DNA methylation
    • Nelson ED, Kavalali ET, Monteggia LM. Activity-dependent suppression of miniature neurotransmission through the regulation of DNA methylation. J Neurosci 28: 395-406, 2008.
    • (2008) J Neurosci , vol.28 , pp. 395-406
    • Nelson, E.D.1    Kavalali, E.T.2    Monteggia, L.M.3
  • 254
    • 52149108919 scopus 로고    scopus 로고
    • S-nitrosylation of histone deacetylase 2 induces chromatin remodelling in neurons
    • Nott A, Watson PM, Robinson JD, Crepaldi L, Riccio A. S-nitrosylation of histone deacetylase 2 induces chromatin remodelling in neurons. Nature 455: 411-415, 2008.
    • (2008) Nature , vol.455 , pp. 411-415
    • Nott, A.1    Watson, P.M.2    Robinson, J.D.3    Crepaldi, L.4    Riccio, A.5
  • 256
    • 47149100122 scopus 로고    scopus 로고
    • Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses
    • Oberlander TF, Weinberg J, Papsdorf M, Grunau R, Misri S, Devlin AM. Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses. Epigenetics 3: 97-106, 2008.
    • (2008) Epigenetics , vol.3 , pp. 97-106
    • Oberlander, T.F.1    Weinberg, J.2    Papsdorf, M.3    Grunau, R.4    Misri, S.5    Devlin, A.M.6
  • 257
    • 20344407807 scopus 로고    scopus 로고
    • Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas
    • Ohgaki H, Kleihues P. Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas. J Neuropathol Exp Neurol 64: 479-489, 2005.
    • (2005) J Neuropathol Exp Neurol , vol.64 , pp. 479-489
    • Ohgaki, H.1    Kleihues, P.2
  • 258
    • 0033018277 scopus 로고    scopus 로고
    • Truncated CBP protein leads to classical Rubinstein-Taybi syndrome phenotypes in mice: Implications for a dominant-negative mechanism
    • Oike Y, Hata A, Mamiya T, Kaname T, Noda Y, Suzuki M, Yasue H, Nabeshima T, Araki K, Yamamura K. Truncated CBP protein leads to classical Rubinstein-Taybi syndrome phenotypes in mice: implications for a dominant-negative mechanism. Hum Mol Genet 8: 387-396, 1999.
    • (1999) Hum Mol Genet , vol.8 , pp. 387-396
    • Oike, Y.1    Hata, A.2    Mamiya, T.3    Kaname, T.4    Noda, Y.5    Suzuki, M.6    Yasue, H.7    Nabeshima, T.8    Araki, K.9    Yamamura, K.10
  • 259
    • 34748917182 scopus 로고    scopus 로고
    • Transgenic mice expressing an inhibitory truncated form of p300. exhibit long-term memory defi{ligature}cits
    • Oliveira AMM, Wood MA, McDonough CB. Transgenic mice expressing an inhibitory truncated form of p300. exhibit long-term memory defi{ligature}cits. Learn Mem 14: 564-572, 2007.
    • (2007) Learn Mem , vol.14 , pp. 564-572
    • Oliveira, A.M.M.1    Wood, M.A.2    McDonough, C.B.3
  • 261
    • 43649105135 scopus 로고    scopus 로고
    • Brain chromatin remodeling: A novel mechanism of alcoholism
    • Pandey SC, Ugale R, Zhang H, Tang L, Prakash A. Brain chromatin remodeling: a novel mechanism of alcoholism. J Neurosci 28: 3729-3737, 2008.
    • (2008) J Neurosci , vol.28 , pp. 3729-3737
    • Pandey, S.C.1    Ugale, R.2    Zhang, H.3    Tang, L.4    Prakash, A.5
  • 262
    • 62549093116 scopus 로고    scopus 로고
    • The pathogenesis of Friedreich ataxia and the structure and function of frataxin
    • Pandolfo M, Pastore A. The pathogenesis of Friedreich ataxia and the structure and function of frataxin. J Neurol 256. Suppl 1: 9-17, 2009.
    • (2009) J Neurol , vol.256 , Issue.SUPPL. 1 , pp. 9-17
    • Pandolfo, M.1    Pastore, A.2
  • 263
    • 15044348382 scopus 로고    scopus 로고
    • HDAC-3 participates in the repression of e2f-dependent gene transcription in primary differentiated neurons
    • Panteleeva I, Rouaux C, Larmet Y, Boutillier S, Loeffler JP, Boutillier AL. HDAC-3 participates in the repression of e2f-dependent gene transcription in primary differentiated neurons. Ann NY Acad Sci 1030: 656-660, 2004.
    • (2004) Ann NY Acad Sci , vol.1030 , pp. 656-660
    • Panteleeva, I.1    Rouaux, C.2    Larmet, Y.3    Boutillier, S.4    Loeffler, J.P.5    Boutillier, A.L.6
  • 264
    • 0034710902 scopus 로고    scopus 로고
    • Constitutive expression of the neuron-restrictive silencer factor (NRSF)/REST in differentiating neurons disrupts neuronal gene expression and causes axon pathfi{ligature}nding errors in vivo
    • Paquette AJ, Perez SE, Anderson DJ. Constitutive expression of the neuron-restrictive silencer factor (NRSF)/REST in differentiating neurons disrupts neuronal gene expression and causes axon pathfi{ligature}nding errors in vivo. Proc Natl Acad Sci USA 97: 12318-12323, 2000.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 12318-12323
    • Paquette, A.J.1    Perez, S.E.2    Anderson, D.J.3
  • 265
    • 39149113093 scopus 로고    scopus 로고
    • Epigenetic regulation of kappa opioid receptor gene in neuronal differentiation
    • Park SW, He Y, Ha SG, Loh HH, Wei LN. Epigenetic regulation of kappa opioid receptor gene in neuronal differentiation. Neuro-science 151: 1034-1041, 2008.
    • (2008) Neuro-science , vol.151 , pp. 1034-1041
    • Park, S.W.1    He, Y.2    Ha, S.G.3    Loh, H.H.4    Wei, L.N.5
  • 267
    • 58549107423 scopus 로고    scopus 로고
    • Repeated alcohol administration during adolescence causes changes in the mesolimbic dopaminergic and glutamatergic systems and promotes alcohol intake in the adult rat
    • Pascual M, Boix J, Felipo V, Guerri C. Repeated alcohol administration during adolescence causes changes in the mesolimbic dopaminergic and glutamatergic systems and promotes alcohol intake in the adult rat. J Neurochem 108: 920-931, 2009.
    • (2009) J Neurochem , vol.108 , pp. 920-931
    • Pascual, M.1    Boix, J.2    Felipo, V.3    Guerri, C.4
  • 271
    • 15044366201 scopus 로고    scopus 로고
    • Methylation of histones: Playing memory with DNA
    • Peters AH, Schubeler D. Methylation of histones: playing memory with DNA. Curr Opin Cell Biol 17: 230-238, 2005.
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 230-238
    • Peters, A.H.1    Schubeler, D.2
  • 273
    • 0037547166 scopus 로고    scopus 로고
    • In search of general mechanisms for long-lasting plasticity: Aplysia and the hippocampus
    • Pittenger C, Kandel ER. In search of general mechanisms for long-lasting plasticity: Aplysia and the hippocampus. Philos Trans R Soc Lond B Biol Sci 358: 757-763, 2003.
    • (2003) Philos Trans R Soc Lond B Biol Sci , vol.358 , pp. 757-763
    • Pittenger, C.1    Kandel, E.R.2
  • 274
    • 52949099506 scopus 로고    scopus 로고
    • A receptor promoter hypermethylation in suicide brain: Implications for the involvement of epigenetic processes
    • Poulter MO, Du L, Weaver IC, Palkovits M, Faludi G, Merali Z, Szyf M, Anisman H. GABAA receptor promoter hypermethylation in suicide brain: implications for the involvement of epigenetic processes. Biol Psychiatry 64: 645-652, 2008.
    • (2008) Biol Psychiatry , vol.64 , pp. 645-652
    • Poulter, M.O.1    Du, L.2    Weaver, I.C.3    Palkovits, M.4    Faludi, G.5    Merali, Z.6    Szyf, M.7    Anisman, H.8
  • 275
    • 27144504752 scopus 로고    scopus 로고
    • Histones in functional diversifi{ligature}cation. Core histone variants
    • Pusarla RH, Bhargava P. Histones in functional diversifi{ligature}cation. Core histone variants. FEBS J 272: 5149-5168, 2005.
    • (2005) FEBS J , vol.272 , pp. 5149-5168
    • Pusarla, R.H.1    Bhargava, P.2
  • 276
    • 33847150936 scopus 로고    scopus 로고
    • Developmental downregulation of histone posttranslational modifi{ligature}cations regulates visual cortical plasticity
    • Putignano E, Lonetti G, Cancedda L, Ratto G, Costa M, Maffei L, Pizzorusso T. Developmental downregulation of histone posttranslational modifi{ligature}cations regulates visual cortical plasticity. Neuron 53: 747-759, 2007.
    • (2007) Neuron , vol.53 , pp. 747-759
    • Putignano, E.1    Lonetti, G.2    Cancedda, L.3    Ratto, G.4    Costa, M.5    Maffei, L.6    Pizzorusso, T.7
  • 277
    • 4844224132 scopus 로고    scopus 로고
    • Sodium 4-phenylbutyrate protects against cerebral ischemic injury
    • Qi X, Hosoi T, Okuma Y, Kaneko M, Nomura Y. Sodium 4-phenylbutyrate protects against cerebral ischemic injury. Mol Pharmacol 66: 899-908, 2004.
    • (2004) Mol Pharmacol , vol.66 , pp. 899-908
    • Qi, X.1    Hosoi, T.2    Okuma, Y.3    Kaneko, M.4    Nomura, Y.5
  • 279
    • 0034625064 scopus 로고    scopus 로고
    • Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a
    • Ramsahoye BH, Biniszkiewicz D, Lyko F, Clark V, Bird AP, Jaenisch R. Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a. Proc Natl Acad Sci USA 97: 5237-5242, 2000.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 5237-5242
    • Ramsahoye, B.H.1    Biniszkiewicz, D.2    Lyko, F.3    Clark, V.4    Bird, A.P.5    Jaenisch, R.6
  • 280
    • 0027510643 scopus 로고
    • The de facto US mental and addictive disorders service system. Epidemiologic catchment area prospective 1-year prevalence rates of disorders and services
    • Regier DA, Narrow WE, Rae DS, Manderscheid RW, Locke BZ, Goodwin FK. The de facto US mental and addictive disorders service system. Epidemiologic catchment area prospective 1-year prevalence rates of disorders and services. Arch Gen Psychiatry 50: 85-94, 1993.
    • (1993) Arch Gen Psychiatry , vol.50 , pp. 85-94
    • Regier, D.A.1    Narrow, W.E.2    Rae, D.S.3    Manderscheid, R.W.4    Locke, B.Z.5    Goodwin, F.K.6
  • 281
    • 0035234557 scopus 로고    scopus 로고
    • Genomic imprinting: Parental infl{ligature}uence on the genome
    • Reik W, Walter J. Genomic imprinting: parental infl{ligature}uence on the genome. Nat Rev Genet 2: 21-32, 2001.
    • (2001) Nat Rev Genet , vol.2 , pp. 21-32
    • Reik, W.1    Walter, J.2
  • 282
    • 3042651448 scopus 로고    scopus 로고
    • Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: Potential roles of histone deacetylase inhibition and heat shock protein induction
    • Ren M, Leng Y, Jeong M, Leeds PR, Chuang DM. Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: potential roles of histone deacetylase inhibition and heat shock protein induction. J Neurochem 89: 1358-1367, 2004.
    • (2004) J Neurochem , vol.89 , pp. 1358-1367
    • Ren, M.1    Leng, Y.2    Jeong, M.3    Leeds, P.R.4    Chuang, D.M.5
  • 286
    • 73449108418 scopus 로고    scopus 로고
    • Epigenetic mechanisms in the dentate gyrus act as a molecular switch in hippocampus-associated memory formation
    • Reul JM, Hesketh SA, Collins A, Mecinas MG. Epigenetic mechanisms in the dentate gyrus act as a molecular switch in hippocampus-associated memory formation. Epigenetics 4: 434-439, 2009.
    • (2009) Epigenetics , vol.4 , pp. 434-439
    • Reul, J.M.1    Hesketh, S.A.2    Collins, A.3    Mecinas, M.G.4
  • 289
    • 0034305821 scopus 로고    scopus 로고
    • DNA methylation in health and disease
    • Robertson KD, Wolffe AP. DNA methylation in health and disease. Nat Rev Genet 1: 11-19, 2000.
    • (2000) Nat Rev Genet , vol.1 , pp. 11-19
    • Robertson, K.D.1    Wolffe, A.P.2
  • 290
    • 0034001908 scopus 로고    scopus 로고
    • Transcriptional repression by neuron-restrictive silencer factor is mediated via the Sin3-histone deacetylase complex
    • Roopra A, Sharling L, Wood IC, Briggs T, Bachfischer U, Paquette AJ, Buckley NJ. Transcriptional repression by neuron-restrictive silencer factor is mediated via the Sin3-histone deacetylase complex. Mol Cell Biol 20: 2147-2157, 2000.
    • (2000) Mol Cell Biol , vol.20 , pp. 2147-2157
    • Roopra, A.1    Sharling, L.2    Wood, I.C.3    Briggs, T.4    Bachfischer, U.5    Paquette, A.J.6    Buckley, N.J.7
  • 291
    • 33744792310 scopus 로고    scopus 로고
    • Sensors and signals: A coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response
    • Rosenfeld MG, Lunyak VV, Glass CK. Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response. Genes Dev 20: 1405-1428, 2006.
    • (2006) Genes Dev , vol.20 , pp. 1405-1428
    • Rosenfeld, M.G.1    Lunyak, V.V.2    Glass, C.K.3
  • 292
    • 63449085750 scopus 로고    scopus 로고
    • Lasting epigenetic infl{ligature}uence of early-life adversity on the BDNF gene
    • Roth TL, Lubin FD, Funk AJ, Sweatt JD. Lasting epigenetic infl{ligature}uence of early-life adversity on the BDNF gene. Biol Psychiatry 65: 760-769, 2009.
    • (2009) Biol Psychiatry , vol.65 , pp. 760-769
    • Roth, T.L.1    Lubin, F.D.2    Funk, A.J.3    Sweatt, J.D.4
  • 293
    • 0347624644 scopus 로고    scopus 로고
    • Critical loss of CBP/p300. histone acetylase activity by caspase-6 during neurodegeneration
    • Rouaux C, Jokic N, Mbebi C, Boutillier S, Loeffler JP, Boutillier AL. Critical loss of CBP/p300. histone acetylase activity by caspase-6 during neurodegeneration. EMBO J 22: 6537-6549, 2003.
    • (2003) EMBO J , vol.22 , pp. 6537-6549
    • Rouaux, C.1    Jokic, N.2    Mbebi, C.3    Boutillier, S.4    Loeffler, J.P.5    Boutillier, A.L.6
  • 294
    • 34250612194 scopus 로고    scopus 로고
    • Sodium valproate exerts neuroprotective effects in vivo through CREB-binding protein-dependent mechanisms but does not improve survival in an amyotrophic lateral sclerosis mouse model
    • Rouaux C, Panteleeva I, Rene F, Gonzalez de Aguilar JL, Echaniz-Laguna A, Dupuis L, Menger Y, Boutillier AL, Loeffler JP. Sodium valproate exerts neuroprotective effects in vivo through CREB-binding protein-dependent mechanisms but does not improve survival in an amyotrophic lateral sclerosis mouse model. J Neurosci 27: 5535-5545, 2007.
    • (2007) J Neurosci , vol.27 , pp. 5535-5545
    • Rouaux, C.1    Panteleeva, I.2    Rene, F.3    Gonzalez de Aguilar, J.L.4    Echaniz-Laguna, A.5    Dupuis, L.6    Menger, Y.7    Boutillier, A.L.8    Loeffler, J.P.9
  • 297
    • 0032582615 scopus 로고    scopus 로고
    • Neuronal apoptosis induced by histone deacetylase inhibitors
    • Salminen A, Tapiola T, Korhonen P, Suuronen T. Neuronal apoptosis induced by histone deacetylase inhibitors. Brain Res 61: 203-206, 1998.
    • (1998) Brain Res , vol.61 , pp. 203-206
    • Salminen, A.1    Tapiola, T.2    Korhonen, P.3    Suuronen, T.4
  • 298
    • 70449530489 scopus 로고    scopus 로고
    • Selective boosting of transcriptional and behavioral responses to drugs of abuse by histone deacetylase inhibition
    • Sanchis-Segura C, Lopez-Atalaya JP, Barco A. Selective boosting of transcriptional and behavioral responses to drugs of abuse by histone deacetylase inhibition. Neuropsychopharmacology 34: 2642-2654, 2009.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 2642-2654
    • Sanchis-Segura, C.1    Lopez-Atalaya, J.P.2    Barco, A.3
  • 300
    • 0037464488 scopus 로고    scopus 로고
    • Presenilin 1 gene silencing by S-adenosylmethionine: A treatment for Alzheimer disease?
    • Scarpa S, Fuso A, D'Anselmi F, Cavallaro RA. Presenilin 1 gene silencing by S-adenosylmethionine: a treatment for Alzheimer disease? FEBS Lett 541: 145-148, 2003.
    • (2003) FEBS Lett , vol.541 , pp. 145-148
    • Scarpa, S.1    Fuso, A.2    D'anselmi, F.3    Cavallaro, R.A.4
  • 302
    • 34250161829 scopus 로고    scopus 로고
    • Antidepressant-like effects of the histone deacetylase inhibitor, sodium butyrate, in the mouse
    • Schroeder FA, Lin CL, Crusio WE, Akbarian S. Antidepressant-like effects of the histone deacetylase inhibitor, sodium butyrate, in the mouse. Biol Psychiatry 62: 55-64, 2007.
    • (2007) Biol Psychiatry , vol.62 , pp. 55-64
    • Schroeder, F.A.1    Lin, C.L.2    Crusio, W.E.3    Akbarian, S.4
  • 304
    • 36248940166 scopus 로고    scopus 로고
    • Glucocorticoids, developmental "programming" and the risk of affective dysfunction
    • Seckl JR. Glucocorticoids, developmental "programming" and the risk of affective dysfunction. Prog Brain Res 167: 17-34, 2008.
    • (2008) Prog Brain Res , vol.167 , pp. 17-34
    • Seckl, J.R.1
  • 305
    • 33746468080 scopus 로고    scopus 로고
    • Glucocorticoid "programming" and PTSD risk
    • Seckl JR, Meaney MJ. Glucocorticoid "programming" and PTSD risk. Ann NY Acad Sci 1071: 351-378, 2006.
    • (2006) Ann NY Acad Sci , vol.1071 , pp. 351-378
    • Seckl, J.R.1    Meaney, M.J.2
  • 306
    • 0029371656 scopus 로고
    • Rubinstein-Taybi syndrome: Cranial MR imaging fi{ligature}ndings
    • Sener RN. Rubinstein-Taybi syndrome: cranial MR imaging fi{ligature}ndings. Comput Med Imaging Graph 19: 417-418, 1995.
    • (1995) Comput Med Imaging Graph , vol.19 , pp. 417-418
    • Sener, R.N.1
  • 308
    • 36849063138 scopus 로고    scopus 로고
    • Histone deactylase 1 expression is increased in the prefrontal cortex of schizophrenia subjects: Analysis of the National Brain Databank microarray collection
    • Sharma RP, Grayson DR, Gavin DP. Histone deactylase 1 expression is increased in the prefrontal cortex of schizophrenia subjects: analysis of the National Brain Databank microarray collection. Schizophr Res 98: 111-117, 2008.
    • (2008) Schizophr Res , vol.98 , pp. 111-117
    • Sharma, R.P.1    Grayson, D.R.2    Gavin, D.P.3
  • 309
    • 22344446199 scopus 로고    scopus 로고
    • Histone modifi{ligature}cations affect timing of oligodendrocyte progenitor differentiation in the developing rat brain
    • Shen S, Li J, Casaccia-Bonnefil P. Histone modifi{ligature}cations affect timing of oligodendrocyte progenitor differentiation in the developing rat brain. J Cell Biol 169: 577-589, 2005.
    • (2005) J Cell Biol , vol.169 , pp. 577-589
    • Shen, S.1    Li, J.2    Casaccia-Bonnefil, P.3
  • 310
    • 38949136675 scopus 로고    scopus 로고
    • Epigenetic memory loss in aging oligodendrocytes in the corpus callosum
    • Shen S, Liu A, Li J, Wolubah C, Casaccia-Bonnefil P. Epigenetic memory loss in aging oligodendrocytes in the corpus callosum. Neurobiol Aging 29: 452-463, 2008.
    • (2008) Neurobiol Aging , vol.29 , pp. 452-463
    • Shen, S.1    Liu, A.2    Li, J.3    Wolubah, C.4    Casaccia-Bonnefil, P.5
  • 311
    • 0344824404 scopus 로고    scopus 로고
    • Histone sumoylation is associated with transcriptional repression
    • Shiio Y, Eisenman RN. Histone sumoylation is associated with transcriptional repression. Proc Natl Acad Sci USA 100: 13225-13230, 2003.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 13225-13230
    • Shiio, Y.1    Eisenman, R.N.2
  • 312
    • 33746324216 scopus 로고    scopus 로고
    • Chromatin modifi{ligature}cations by methylation and ubiquitination: Implications in the regulation of gene expression
    • Shilatifard A. Chromatin modifi{ligature}cations by methylation and ubiquitination: implications in the regulation of gene expression. Annu Rev Biochem 75: 243-269, 2006.
    • (2006) Annu Rev Biochem , vol.75 , pp. 243-269
    • Shilatifard, A.1
  • 313
    • 20444363086 scopus 로고    scopus 로고
    • Wnt signaling controls the timing of oligodendrocyte development in the spinal cord
    • Shimizu T, Kagawa T, Wada T, Muroyama Y, Takada S, Ikenaka K. Wnt signaling controls the timing of oligodendrocyte development in the spinal cord. Dev Biol 282: 397-410, 2005.
    • (2005) Dev Biol , vol.282 , pp. 397-410
    • Shimizu, T.1    Kagawa, T.2    Wada, T.3    Muroyama, Y.4    Takada, S.5    Ikenaka, K.6
  • 314
    • 33846632355 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors increase neuronal differentiation in adult forebrain precursor cells
    • Siebzehnrubl FA, Buslei R, Eyupoglu IY, Seufert S, Hahnen E, Blumcke I. Histone deacetylase inhibitors increase neuronal differentiation in adult forebrain precursor cells. Exp Brain Res 176: 672-678, 2007.
    • (2007) Exp Brain Res , vol.176 , pp. 672-678
    • Siebzehnrubl, F.A.1    Buslei, R.2    Eyupoglu, I.Y.3    Seufert, S.4    Hahnen, E.5    Blumcke, I.6
  • 317
    • 0036845254 scopus 로고    scopus 로고
    • Conrad Hal Waddington: The last Renaissance biologist?
    • Slack JM. Conrad Hal Waddington: the last Renaissance biologist? Nat Rev Genet 3: 889-895, 2002.
    • (2002) Nat Rev Genet , vol.3 , pp. 889-895
    • Slack, J.M.1
  • 324
    • 0035830503 scopus 로고    scopus 로고
    • Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms
    • Sun Y, Nadal-Vicens M, Misono S, Lin MZ, Zubiaga A, Hua X, Fan G, Greenberg ME. Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms. Cell 104: 365-376, 2001.
    • (2001) Cell , vol.104 , pp. 365-376
    • Sun, Y.1    Nadal-Vicens, M.2    Misono, S.3    Lin, M.Z.4    Zubiaga, A.5    Hua, X.6    Fan, G.7    Greenberg, M.E.8
  • 325
    • 43749098985 scopus 로고    scopus 로고
    • DNA methylation landscapes: Provocative insights from epigenomics
    • Suzuki MM, Bird A. DNA methylation landscapes: provocative insights from epigenomics. Nat Rev Genet 9: 465-476, 2008.
    • (2008) Nat Rev Genet , vol.9 , pp. 465-476
    • Suzuki, M.M.1    Bird, A.2
  • 326
    • 0035873614 scopus 로고    scopus 로고
    • Increased histone acetyltransferase and lysine acetyltransferase activity and biphasic activation of the ERK/ RSK cascade in insular cortex during novel taste learning
    • Swank MW, Sweatt JD. Increased histone acetyltransferase and lysine acetyltransferase activity and biphasic activation of the ERK/ RSK cascade in insular cortex during novel taste learning. J Neurosci 21: 3383-3391, 2001.
    • (2001) J Neurosci , vol.21 , pp. 3383-3391
    • Swank, M.W.1    Sweatt, J.D.2
  • 327
    • 58149308474 scopus 로고    scopus 로고
    • Experience-dependent epigenetic modifi{ligature}cations in the central nervous system
    • Sweatt JD. Experience-dependent epigenetic modifi{ligature}cations in the central nervous system. Biol Psychiatry 65: 191-197, 2009.
    • (2009) Biol Psychiatry , vol.65 , pp. 191-197
    • Sweatt, J.D.1
  • 328
    • 0035166616 scopus 로고    scopus 로고
    • The neuronal MAP kinase cascade: A biochemical signal integration system subserving synaptic plasticity and memory
    • Sweatt JD. The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory. J Neurochem 76: 1-10, 2001.
    • (2001) J Neurochem , vol.76 , pp. 1-10
    • Sweatt, J.D.1
  • 329
    • 68349091505 scopus 로고    scopus 로고
    • The early life environment and the epigenome
    • Szyf M. The early life environment and the epigenome. Biochim Biophys Acta 1790: 878-885, 2009.
    • (2009) Biochim Biophys Acta , vol.1790 , pp. 878-885
    • Szyf, M.1
  • 330
    • 56749106679 scopus 로고    scopus 로고
    • Epigenetic analysis reveals a euchromatic confi{ligature}guration in the FMR1 unmethylated full mutations
    • Tabolacci E, Moscato U, Zalfa F, Bagni C, Chiurazzi P, Neri G. Epigenetic analysis reveals a euchromatic confi{ligature}guration in the FMR1 unmethylated full mutations. Eur J Hum Genet 16: 1487-1498, 2008.
    • (2008) Eur J Hum Genet , vol.16 , pp. 1487-1498
    • Tabolacci, E.1    Moscato, U.2    Zalfa, F.3    Bagni, C.4    Chiurazzi, P.5    Neri, G.6
  • 331
    • 18844398832 scopus 로고    scopus 로고
    • Differential epigenetic modifi{ligature}cations in the FMR1 gene of the fragile X syndrome after reactivating pharmacological treatments
    • Tabolacci E, Pietrobono R, Moscato U, Oostra BA, Chiurazzi P, Neri G. Differential epigenetic modifi{ligature}cations in the FMR1 gene of the fragile X syndrome after reactivating pharmacological treatments. Eur J Hum Genet 13: 641-648, 2005.
    • (2005) Eur J Hum Genet , vol.13 , pp. 641-648
    • Tabolacci, E.1    Pietrobono, R.2    Moscato, U.3    Oostra, B.A.4    Chiurazzi, P.5    Neri, G.6
  • 333
    • 77949874234 scopus 로고    scopus 로고
    • Histone variants: Ancient wrap artists of the epigenome
    • Talbert PB, Henikoff S. Histone variants: ancient wrap artists of the epigenome. Nat Rev Mol Cell Biol 11: 264-275.
    • Nat Rev Mol Cell Biol , vol.11 , pp. 264-275
    • Talbert, P.B.1    Henikoff, S.2
  • 334
    • 0035917322 scopus 로고    scopus 로고
    • Homo-oligomerisation and nuclear localisation of mouse histone deacetylase 1
    • Taplick J, Kurtev V, Kroboth K, Posch M, Lechner T, Seiser C. Homo-oligomerisation and nuclear localisation of mouse histone deacetylase 1. J Mol Biol 308: 27-38, 2001.
    • (2001) J Mol Biol , vol.308 , pp. 27-38
    • Taplick, J.1    Kurtev, V.2    Kroboth, K.3    Posch, M.4    Lechner, T.5    Seiser, C.6
  • 335
    • 35848961668 scopus 로고    scopus 로고
    • How chromatin-binding modules interpret histone modifi{ligature}cations: Lessons from professional pocket pickers
    • Taverna SD, Li H, Ruthenburg AJ, Allis CD, Patel DJ. How chromatin-binding modules interpret histone modifi{ligature}cations: lessons from professional pocket pickers. Nat Struct Mol Biol 14: 1025-1040, 2007.
    • (2007) Nat Struct Mol Biol , vol.14 , pp. 1025-1040
    • Taverna, S.D.1    Li, H.2    Ruthenburg, A.J.3    Allis, C.D.4    Patel, D.J.5
  • 336
    • 0035499887 scopus 로고    scopus 로고
    • The development of neural stem cells
    • Temple S. The development of neural stem cells. Nature 414: 112-117, 2001.
    • (2001) Nature , vol.414 , pp. 112-117
    • Temple, S.1
  • 340
    • 33645357786 scopus 로고    scopus 로고
    • Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action
    • Tsankova NM, Berton O, Renthal W, Kumar A, Neve RL, Nestler EJ. Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nature Neurosci 9: 519-525, 2006.
    • (2006) Nature Neurosci , vol.9 , pp. 519-525
    • Tsankova, N.M.1    Berton, O.2    Renthal, W.3    Kumar, A.4    Neve, R.L.5    Nestler, E.J.6
  • 341
    • 3042589127 scopus 로고    scopus 로고
    • Histone modifi{ligature}cations at gene promoter regions in rat hippocampus after acute and chronic electroconvulsive seizures
    • Tsankova NM, Kumar A, Nestler EJ. Histone modifi{ligature}cations at gene promoter regions in rat hippocampus after acute and chronic electroconvulsive seizures. J Neurosci 24: 5603-5610, 2004.
    • (2004) J Neurosci , vol.24 , pp. 5603-5610
    • Tsankova, N.M.1    Kumar, A.2    Nestler, E.J.3
  • 342
    • 0036850325 scopus 로고    scopus 로고
    • Cellular memory and the histone code
    • Turner BM. Cellular memory and the histone code. Cell 111: 285-291, 2002.
    • (2002) Cell , vol.111 , pp. 285-291
    • Turner, B.M.1
  • 343
    • 33845877732 scopus 로고    scopus 로고
    • Defi{ligature}ning an epigenetic code
    • Turner BM. Defi{ligature}ning an epigenetic code. Nat Cell Biol 9: 2-6, 2007.
    • (2007) Nat Cell Biol , vol.9 , pp. 2-6
    • Turner, B.M.1
  • 344
    • 0038057380 scopus 로고    scopus 로고
    • Memorable transcription
    • Turner BM. Memorable transcription. Nat Cell Biol 5: 390-393, 2003.
    • (2003) Nat Cell Biol , vol.5 , pp. 390-393
    • Turner, B.M.1
  • 345
    • 70449426592 scopus 로고    scopus 로고
    • Comprehensive mapping of post-translational modifi{ligature}cations on synaptic, nuclear, his-tone proteins in the adult mouse brain
    • Tweedie-Cullen RY, Reck JM, Mansuy IM. Comprehensive mapping of post-translational modifi{ligature}cations on synaptic, nuclear, his-tone proteins in the adult mouse brain. J Proteome Res 8: 4966-4982, 2009.
    • (2009) J Proteome Res , vol.8 , pp. 4966-4982
    • Tweedie-Cullen, R.Y.1    Reck, J.M.2    Mansuy, I.M.3
  • 347
    • 34250788651 scopus 로고    scopus 로고
    • Epigenetic mechanisms in the context of complex diseases
    • Van Vliet J, Oates NA, Whitelaw E. Epigenetic mechanisms in the context of complex diseases. Cell Mol Life Sci 64: 1531-1538, 2007.
    • (2007) Cell Mol Life Sci , vol.64 , pp. 1531-1538
    • van Vliet, J.1    Oates, N.A.2    Whitelaw, E.3
  • 350
    • 51149203927 scopus 로고
    • Canalization of development and the inheritance of acquired characters
    • Waddington CH. Canalization of development and the inheritance of acquired characters. Nature 150: 563-565, 1942.
    • (1942) Nature , vol.150 , pp. 563-565
    • Waddington, C.H.1
  • 353
    • 76749133172 scopus 로고    scopus 로고
    • Chronic cocaine-induced H3 acetylation and transcriptional activation of CaMKIIalpha in the nucleus accumbens is critical for motivation for drug reinforcement
    • Wang L, Lv Z, Hu Z, Sheng J, Hui B, Sun J, Ma L. Chronic cocaine-induced H3 acetylation and transcriptional activation of CaMKIIalpha in the nucleus accumbens is critical for motivation for drug reinforcement. Neuropsychopharmacology 35: 913-928, 2010.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 913-928
    • Wang, L.1    Lv, Z.2    Hu, Z.3    Sheng, J.4    Hui, B.5    Sun, J.6    Ma, L.7
  • 354
    • 49949108971 scopus 로고    scopus 로고
    • Age-specifi{ligature}c epigenetic drift in late-onset Alzheimer's disease
    • e2698
    • Wang SC, Oelze B, Schumacher A. Age-specifi{ligature}c epigenetic drift in late-onset Alzheimer's disease. PLoS ONE 3: e2698, 2008.
    • (2008) PLoS ONE 3
    • Wang, S.C.1    Oelze, B.2    Schumacher, A.3
  • 355
    • 70449518179 scopus 로고    scopus 로고
    • HDAC inhibitor trichostatin A-inhibited survival of dopaminergic neuronal cells
    • Wang Y, Wang X, Liu L. HDAC inhibitor trichostatin A-inhibited survival of dopaminergic neuronal cells. Neurosci Lett 467: 212-216, 2009.
    • (2009) Neurosci Lett , vol.467 , pp. 212-216
    • Wang, Y.1    Wang, X.2    Liu, L.3
  • 356
    • 69449102464 scopus 로고    scopus 로고
    • Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes
    • Wang Z, Zang C, Cui K, Schones DE, Barski A, Peng W, Zhao K. Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes. Cell 138: 1019-1031, 2009.
    • (2009) Cell , vol.138 , pp. 1019-1031
    • Wang, Z.1    Zang, C.2    Cui, K.3    Schones, D.E.4    Barski, A.5    Peng, W.6    Zhao, K.7
  • 357
    • 40849106789 scopus 로고    scopus 로고
    • Histone ubiquitination: Triggering gene activity
    • Weake VM, Workman JL. Histone ubiquitination: triggering gene activity. Mol Cell 29: 653-663, 2008.
    • (2008) Mol Cell , vol.29 , pp. 653-663
    • Weake, V.M.1    Workman, J.L.2
  • 358
    • 33847093463 scopus 로고    scopus 로고
    • The transcription factor nerve growth factor-inducible protein a mediates epigenetic programming: Altering epigenetic marks by immediate-early genes
    • Weaver IC, D'Alessio AC, Brown SE, Hellstrom IC, Dymov S, Sharma S, Szyf M, Meaney MJ. The transcription factor nerve growth factor-inducible protein a mediates epigenetic programming: altering epigenetic marks by immediate-early genes. J Neurosci 27: 1756-1768, 2007.
    • (2007) J Neurosci , vol.27 , pp. 1756-1768
    • Weaver, I.C.1    D'alessio, A.C.2    Brown, S.E.3    Hellstrom, I.C.4    Dymov, S.5    Sharma, S.6    Szyf, M.7    Meaney, M.J.8
  • 359
    • 33644763991 scopus 로고    scopus 로고
    • Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood
    • Weaver IC, Meaney MJ, Szyf M. Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood. Proc Natl Acad Sci USA 103: 3480-3485, 2006.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 3480-3485
    • Weaver, I.C.1    Meaney, M.J.2    Szyf, M.3
  • 361
    • 28044436691 scopus 로고    scopus 로고
    • Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: Altering epigenetic marking later in life
    • Weaver ICG, Champagne FA, Brown SE, Dymov S, Sharma S, Meaney MJ, Szyf M. Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: altering epigenetic marking later in life. J Neurosci 25: 11045-11054, 2005.
    • (2005) J Neurosci , vol.25 , pp. 11045-11054
    • Weaver, I.C.G.1    Champagne, F.A.2    Brown, S.E.3    Dymov, S.4    Sharma, S.5    Meaney, M.J.6    Szyf, M.7
  • 362
    • 34047116826 scopus 로고    scopus 로고
    • Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
    • Weber M, Hellmann I, Stadler MB, Ramos L, Paabo S, Rebhan M, Schubeler D. Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat Genet 39: 457-466, 2007.
    • (2007) Nat Genet , vol.39 , pp. 457-466
    • Weber, M.1    Hellmann, I.2    Stadler, M.B.3    Ramos, L.4    Paabo, S.5    Rebhan, M.6    Schubeler, D.7
  • 363
    • 33748060215 scopus 로고    scopus 로고
    • Learning induces long-term potentiation in the hippocampus
    • Whitlock JR, Heynen AJ, Shuler MG, Bear MF. Learning induces long-term potentiation in the hippocampus. Science 313: 1093-1097, 2006.
    • (2006) Science , vol.313 , pp. 1093-1097
    • Whitlock, J.R.1    Heynen, A.J.2    Shuler, M.G.3    Bear, M.F.4
  • 364
    • 35549001312 scopus 로고    scopus 로고
    • Genomic imprinting effects on brain development and function
    • Wilkinson LS, Davies W, Isles AR. Genomic imprinting effects on brain development and function. Nat Rev Neurosci 8: 832-843, 2007.
    • (2007) Nat Rev Neurosci , vol.8 , pp. 832-843
    • Wilkinson, L.S.1    Davies, W.2    Isles, A.R.3
  • 365
    • 17144374869 scopus 로고    scopus 로고
    • Transgenic mice expressing a truncated form of CREB-binding protein (CBP) exhibit defi{ligature}cits in hippocampal synaptic plasticity and memory storage
    • Wood MA, Kaplan MP, Park A, Blanchard EJ, Oliveira AM, Lombardi TL, Abel T. Transgenic mice expressing a truncated form of CREB-binding protein (CBP) exhibit defi{ligature}cits in hippocampal synaptic plasticity and memory storage. Learn Mem 12: 111-119, 2005.
    • (2005) Learn Mem , vol.12 , pp. 111-119
    • Wood, M.A.1    Kaplan, M.P.2    Park, A.3    Blanchard, E.J.4    Oliveira, A.M.5    Lombardi, T.L.6    Abel, T.7
  • 366
  • 368
    • 2142809686 scopus 로고    scopus 로고
    • Acetylation of nuclear factor-kappa B in rat amygdala improves long-term but not short-term retention of fear memory
    • Yeh SH, Lin CH, Gean PW. Acetylation of nuclear factor-kappa B in rat amygdala improves long-term but not short-term retention of fear memory. Mol Pharmacol 65: 1286-1292, 2004.
    • (2004) Mol Pharmacol , vol.65 , pp. 1286-1292
    • Yeh, S.H.1    Lin, C.H.2    Gean, P.W.3
  • 370
    • 77950430993 scopus 로고    scopus 로고
    • Epigenetic alterations regulate estradiol-induced enhancement of memory consolidation
    • Zhao Z, Fan L, Frick KM. Epigenetic alterations regulate estradiol-induced enhancement of memory consolidation. Proc Natl Acad Sci USA 107: 5605-5610, 2010.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 5605-5610
    • Zhao, Z.1    Fan, L.2    Frick, K.M.3
  • 372
    • 73349104113 scopus 로고    scopus 로고
    • Active DNA demethylation mediated by DNA glycosylases
    • Zhu JK. Active DNA demethylation mediated by DNA glycosylases. Annu Rev Genet 43: 143-166, 2009.
    • (2009) Annu Rev Genet , vol.43
    • Zhu, J.K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.