Chromatin and beyond: The multitasking roles for SIRT6

Trends in Biochemical Sciences

Volumn 39, Issue 2, 2014, Pages 72-81

  Kugel, Sita ^a   Mostoslavsky, Raul ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

Author keywords

Aging and inflammation; Cancer; DNA repair; Histone deacetylase; Metabolism; Sirtuin 6

Indexed keywords

GLUCOSE; LIPID; SIRTUIN 6;

CHROMATIN; DNA REPAIR; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME STRUCTURE; EXCISION REPAIR; GENOMIC INSTABILITY; GLUCOSE METABOLISM; HEART DISEASE; HEART FAILURE; HEART VENTRICLE HYPERTROPHY; HUMAN; INFLAMMATION; LIFE EXTENSION; LIPID METABOLISM; NEOPLASM; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; TELOMERE;

AGING AND INFLAMMATION; CANCER; DNA REPAIR; HISTONE DEACETYLASE; METABOLISM; SIRTUIN 6;

ANIMALS; CHROMATIN; DIABETES MELLITUS; DNA REPAIR; GENE EXPRESSION REGULATION; GLUCOSE; HEART DISEASES; HUMANS; LIPID METABOLISM; LONGEVITY; MICE; NEOPLASMS; SIGNAL TRANSDUCTION; SIRTUINS; TELOMERE HOMEOSTASIS;

EID: 84892851452     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tibs.2013.12.002     Document Type: Review

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