-
2
-
-
0033554618
-
Association between an alpha(2) macroglobulin DNA polymorphism and late-onset Alzheimer's disease
-
(1999)
Biochem Biophys Res Commun
, vol.264
, pp. 48-50
-
-
Alvarez, V.1
Alvarez, R.2
Lahoz, C.H.3
Martinez, C.4
Pena, J.5
Guisasola, M.6
Salas-Puig, J.7
Moris, G.8
Uria, D.9
Menes, B.B.10
Ribacoba, R.11
Vidal, J.A.12
Sanchez, J.M.13
Coto, E.14
-
3
-
-
0032720496
-
Presenilin 1 controls γ-secretase processing of amyloid precursor protein in pre-Golgi compartments of hippocampal neurons
-
(1999)
J Cell Biol
, vol.147
, pp. 277-294
-
-
Annaert, W.G.1
Levesque, L.2
Craessaerts, K.3
Dierinck, I.4
Snellings, G.5
Westaway, D.6
Zhang, L.7
St. George-Hyslop, P.8
Cordell, B.9
Fraser, P.10
De Strooper, B.11
-
5
-
-
0031278270
-
Lack of apolipprotein E dramatically reduces amyloid β-peptide deposition
-
(1997)
Nature Genet
, vol.17
, pp. 263-264
-
-
Bales, K.R.1
Verina, T.2
Dodel, R.C.3
Du, Y.4
Altstiel, L.5
Bender, M.6
Hyslop, P.7
Johnstone, E.M.8
Little, S.P.9
Cummins, D.J.10
Piccardo, P.11
Ghetti, B.12
Paul, S.M.13
-
6
-
-
0031108103
-
Human presenilin-1, but not familial Alzheimer's disease (FAD) mutants, facilitate Caenorhabditis elegans notch signalling independently of proteolytic processing
-
(1997)
Genes Function
, vol.1
, pp. 149-159
-
-
Baumeister, R.1
Leimer, U.2
Zweckbronner, I.3
Jakubek, C.4
Grunberg, J.5
Haass, C.6
-
8
-
-
0033944273
-
Aspartate mutations in presenilin and γ-secretase inhibitors both impair Notch1 proteolysis and nuclear translocation with relative preservtion of Notch signaling
-
(2000)
J Neurochem
, vol.75
, pp. 583-593
-
-
Berezovska, O.1
Jack, A.C.2
McLean, P.3
Aster, J.C.4
Hicks, C.5
Xia, W.6
Wolfe, M.S.7
Kimberly, W.T.8
Weinmaster, G.9
Selkoe, D.J.10
Hyman, B.T.11
-
9
-
-
0034704198
-
Evidence for genetic linkage of Alzheimer's disease to chromosome 10q
-
In press
-
Science
-
-
Bertram, L.1
Blacker, D.2
Mullin, K.3
Keeney, D.4
Jones, J.5
Basu, S.6
Yhu, S.7
McInnis, M.G.8
Go, R.C.P.9
Vekrellis, K.10
Selkoe, D.J.11
Saunders, A.J.12
Tanzi, R.E.13
-
11
-
-
17344362232
-
Alpha-2 macroglobulin is genetically associated with Alzheimer disease
-
(1998)
Nature Genet
, vol.19
, pp. 357-360
-
-
Blacker, D.1
Wilcox, M.A.2
Laird, N.M.3
Rodes, L.4
Horvath, S.M.5
Go, R.C.6
Perry, R.7
Watson B., Jr.8
Bassett, S.S.9
McInnis, M.G.10
Albert, M.S.11
Hyman, B.T.12
Tanzi, R.E.13
-
12
-
-
0030293676
-
Familial Alzheimer's disease-linked presenilin 1 variants elevate Aβ1-42/1-40 ratio in vitro and in vivo
-
(1996)
Neuron
, vol.17
, pp. 1005-1013
-
-
Borchelt, D.R.1
Thinakaran, G.2
Eckman, C.B.3
Lee, M.K.4
Davenport, F.5
Ratovitsky, T.6
Prada, C.-M.7
Kim, G.8
Seekins, S.9
Yager, D.10
Slunt, H.H.11
Want, R.12
Seeger, M.13
Levey, A.I.14
Gandy, S.E.15
Copeland, N.G.16
Jenkins, N.A.17
Price, D.L.18
Younkin, S.G.19
Sisodia, S.S.20
more..
-
15
-
-
0032488995
-
The proteolytic fragments of the Alzheimer's disease-associated presenilin-1 form heterodimers and occur as a 100- to 150-kDa molecular mass complex
-
(1998)
J Biol Chem
, vol.273
, pp. 3205-3211
-
-
Capell, A.1
Grunberg, J.2
Pesold, B.3
Diehlmann, A.4
Citron, M.5
Nixon, R.6
Beyreuther, K.7
Selkoe, D.J.8
Haass, C.9
-
16
-
-
16944362157
-
Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice
-
(1997)
Nature Med
, vol.3
, pp. 67-72
-
-
Citron, M.1
Westaway, D.2
Xia, W.3
Carlson, G.4
Diehl, T.5
Levesque, G.6
Johnson-Wood, K.7
Lee, M.8
Seubert, P.9
Davis, A.10
Kholodenka, D.11
Motter, R.12
Sherrington, R.13
Perry, B.14
Yao, H.15
Strome, R.16
Lieberburg, I.17
Rommens, J.18
Kim, S.19
Schenk, D.20
Fraser, P.21
St. George-Hyslop, P.22
Selkoe, D.J.23
more..
-
17
-
-
0030769092
-
Alzheimer's Aβ(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells
-
(1997)
Nature Med
, vol.3
, pp. 1021-1023
-
-
Cook, D.G.1
Forman, M.S.2
Sung, J.C.3
Leight, S.4
Kolson, D.L.5
Iwatsubo, T.6
Lee, V.M.Y.7
Doms, R.W.8
-
18
-
-
0028305380
-
Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer's disease
-
(1994)
Nature Genet
, vol.7
, pp. 180-184
-
-
Corder, E.H.1
Saunders, A.M.2
Risch, N.J.3
Strittmatter, W.J.4
Schmechel, D.E.5
Gaskell P.C., Jr.6
Rimmler, J.B.7
Locke, P.A.8
Conneally, P.M.9
Schmader, K.E.10
Small, G.W.11
Roses, A.D.12
Haines, J.L.13
Pericak-Vance, M.A.14
-
19
-
-
0027194791
-
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.E.4
Gaskell P.C., Jr.5
Small, G.W.6
Roses, A.D.7
Haines, J.L.8
Pericak-Vance, M.A.9
-
21
-
-
0032032019
-
An Alzheimer's disease-linked PS1 variant rescues the developmental abnormalities of PS1-deficient embryos
-
(1998)
Neuron
, vol.20
, pp. 603-609
-
-
Davis, J.A.1
Naruse, S.2
Chen, H.3
Eckman, C.4
Younkin, S.5
Price, D.L.6
Borchelt, D.R.7
Sisodia, S.S.8
Wong, P.C.9
-
22
-
-
0033535504
-
A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain
-
(1999)
Nature
, vol.398
, pp. 518-522
-
-
De Strooper, B.1
Annaert, W.2
Cupers, P.3
Saftig, P.4
Craessaerts, K.5
Mumm, J.S.6
Schroeter, E.H.7
Schrijvers, V.8
Wolfe, M.S.9
Ray, W.J.10
Goate, A.11
Kopan, R.12
-
23
-
-
0032556859
-
Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein
-
(1998)
Nature
, vol.391
, pp. 387-390
-
-
De Strooper, B.1
Saftig, P.2
Craessaerts, K.3
Vanderstichele, H.4
Gundula, G.5
Annaert, W.6
Von Figura, K.7
Van Leuven, F.8
-
26
-
-
0034711619
-
Alpha2 macroglobulin and the risk of Alzheimer's disease
-
(2000)
Neurology
, vol.54
, pp. 438-442
-
-
Dodel, R.C.1
Du, Y.2
Bales, K.R.3
Gao, F.4
Eastwood, B.5
Glazier, B.6
Zimmer, R.7
Cordell, B.8
Hake, A.9
Evans, R.10
Gallagher-Thoompson, D.11
Thompson, L.W.12
Tinklenberg, J.R.13
Pfefferbaum, A.14
Sullivan, E.V.15
Yesavage, J.16
Alstiel, L.17
Gasser, T.18
Farlow, M.R.19
Murphy G.M., Jr.20
Paul, S.M.21
more..
-
27
-
-
16044366039
-
Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1
-
(1996)
Nature
, vol.383
, pp. 710-713
-
-
Duff, K.1
Eckman, C.2
Zehr, C.3
Yu, X.4
Prada, C.-M.5
Perez-Tur, J.6
Hutton, M.7
Buee, L.8
Harigaya, Y.9
Yager, D.10
Morgan, D.11
Gordon, M.N.12
Holcomb, L.13
Refolo, L.14
Zenk, B.15
Hardy, J.16
Younkin, S.17
-
29
-
-
0025295039
-
Cleavage of amyloid β-peptide during constitutive processing of its precursor
-
(1990)
Science
, vol.248
, pp. 1122-1124
-
-
Esch, F.S.1
Keim, P.S.2
Beattie, E.C.3
Blacher, R.W.4
Culwell, A.R.5
Oltersdorf, T.6
McClure, D.7
Ward, P.J.8
-
30
-
-
0033780472
-
Transition-state analog inhibitors of γ-secretase bind directly to Presenilin-1
-
(2000)
Nat Cell Biol
, vol.2
, pp. 428-434
-
-
Esler, W.P.1
Kimberly, W.T.2
Ostaszewski, B.L.3
Diehl, T.S.4
Moore, C.L.5
Tsai, J.-Y.6
Rahmati, T.7
Xia, W.8
Selkoe, D.J.9
Wolfe, M.S.10
-
33
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein
-
(1995)
Nature
, vol.373
, pp. 523-527
-
-
Games, D.1
Adams, D.2
Alessandrini, R.3
Barbour, R.4
Berthelette, P.5
Blackwell, C.6
Carr, T.7
Clemens, J.8
Donaldson, T.9
Gillespie, F.10
Guido, T.11
Hagopian, S.12
Johnson-Wood, K.13
Khan, K.14
Lee, M.15
Leibowitz, P.16
Leiberburg, I.17
Little, S.18
Masliah, E.19
McConlogue, L.20
Montoya-Zavala, M.21
Mucke, L.22
Paganini, L.23
Penniman, E.24
Power, M.25
Schenk, D.26
Seubert, P.27
Snyder, B.28
Soriano, F.29
Tan, H.30
Vitale, J.31
Wadsworth, S.32
Wolozin, B.33
Zhao, J.34
more..
-
36
-
-
0027492366
-
Amyloid precursor protein (APP) in the striatum in Alzheimer's disease: An immunohistochemical study
-
(1993)
J Neuropathol Exp Neurol
, vol.52
, pp. 22-30
-
-
Gearing, M.1
Wilson, R.W.2
Unger, E.R.3
Shelton, E.R.4
Chan, H.W.5
Masters, C.L.6
Beyreuther, K.7
Mirra, S.S.8
-
37
-
-
0033401526
-
Presenilin-1 forms complexes with the cadherin/catenin cell-cell adhesion system and is recruited to intercellular and synaptic contacts
-
(1999)
Mol Cell
, vol.4
, pp. 893-902
-
-
Georgakopoulos, A.1
Marambaud, P.2
Efthimiopuolos, S.3
Shioi, J.4
Cui, W.5
Li, H.C.6
Schutte, M.7
Gordon, R.8
Holstein, G.R.9
Martinelli, G.10
Mehta, P.11
Friedrich V.L., Jr.12
Robakis, N.K.13
-
40
-
-
0026088977
-
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
-
(1991)
Nature
, vol.349
, pp. 704-706
-
-
Goate, A.1
Chartier-Harlin, M.C.2
Mullan, M.3
Brown, J.4
Crawford, F.5
Fidani, L.6
Guiffra, L.7
Haynes, A.8
Irving, N.9
James, L.10
Mant, R.11
Newton, P.12
Rooke, K.13
Roques, P.14
Talbot, C.15
Pericak-Vance, M.16
Roses, A.17
Williamson, R.18
Rossor, M.19
Owen, M.20
Hardy, J.21
more..
-
43
-
-
0033622324
-
42 accumulation in human brain
-
(2000)
Am J Pathol
, vol.156
, pp. 15-20
-
-
Gouras, G.K.1
Tasi, J.2
Naslund, J.3
Vincent, B.4
Edgar, M.5
Greenfield, J.P.6
Haroutunian, V.7
Buxbaum, J.D.8
Xu, H.9
Greengard, P.10
Relkin, N.R.11
-
45
-
-
0032525964
-
LIN-12/Notch signaling: Lessons from worms and flies
-
(1998)
Genes Dev
, vol.12
, pp. 1751-1762
-
-
Greenwald, I.1
-
46
-
-
0001360461
-
Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 7611-7615
-
-
Griffin, W.S.T.1
Stanley, L.C.2
Ling, C.3
White, L.4
MacLeod, V.5
Perrot, L.J.6
White III, C.L.7
Araoz, C.8
-
49
-
-
0026325645
-
Processing of β-amyloid precursor protein in microglia and astrocytes favors a localization in internal vesicles over constitutive secretion
-
(1991)
J Neurosci
, vol.11
, pp. 3783-3793
-
-
Haass, C.1
Hung, A.Y.2
Selkoe, D.J.3
-
53
-
-
0028866435
-
The Swedish mutation causes early-onset Alzheimer's disease by β-secretase cleavage within the secretory pathway
-
(1995)
Nature Med
, vol.1
, pp. 1291-1296
-
-
Haass, C.1
Lemere, C.A.2
Capell, A.3
Citron, M.4
Seubert, P.5
Schenk, D.6
Lannfelt, L.7
Selkoe, D.J.8
-
54
-
-
0026646604
-
Amyloid β-peptide is produced by cultured cells during normal metabolism
-
(1992)
Nature
, vol.359
, pp. 322-325
-
-
Haass, C.1
Schlossmacher, M.2
Hung, A.Y.3
Vigo-Pelfrey, C.4
Mellon, A.5
Ostaszewski, B.6
Lieberburg, I.7
Koo, E.H.8
Schenk, D.9
Teplow, D.10
Selkoe, D.J.11
-
59
-
-
0033570337
-
Protofibrillar intermediates of amyloid β-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons
-
(1999)
J Neurosci
, vol.19
, pp. 8876-8884
-
-
Hartley, D.1
Walsh, D.M.2
Ye, C.P.3
Diehl, T.4
Vasquez, S.5
Vassilev, P.M.6
Teplow, D.B.7
Selkoe, D.J.8
-
60
-
-
0026879650
-
Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the β-amyloid precursor protein gene
-
(1992)
Nature Genet
, vol.1
, pp. 218-221
-
-
Hendriks, L.1
Van Dulin, C.M.2
Cras, P.3
Cruts, M.4
Van Hul, W.5
Van Harskamp, F.6
Warren, A.7
McInnis, M.G.8
Antonarakis, S.E.9
Martin, J.-J.10
Hofman, A.11
Van Broeckhoven, C.12
-
61
-
-
0031914718
-
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
-
(1998)
Nature Med
, vol.4
, pp. 97-100
-
-
Holcomb, L.1
Gordon, M.N.2
McGowan, E.3
Yu, X.4
Benkovic, S.5
Jantzen, P.6
Wright, K.7
Saad, I.8
Mueller, R.9
Morgan, D.10
Sanders, S.11
Zehr, C.12
O'Campo13
Hardy, J.14
Prada, C.M.15
Eckman, C.16
Younkin, S.17
Hsiao, K.18
Duff, K.19
-
62
-
-
0033559412
-
Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease
-
(1999)
J Clin Invest
, vol.103
-
-
Holtzman, D.M.1
Bales, K.R.2
Wu, S.3
Bhat, P.4
Parsadanian, M.5
Fagan, A.M.6
Chang, L.K.7
Sun, Y.8
Paul, S.M.9
-
64
-
-
13044287361
-
Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 3228-3233
-
-
Hsia, A.Y.1
Masliah, E.2
McConlogue, L.3
Yu, G.Q.4
Tatsuno, G.5
Hu, K.6
Kholodenko, D.7
Malenka, R.C.8
Nicoll, R.A.9
Mucke, L.10
-
65
-
-
0029742199
-
Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Ekman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
66
-
-
0028057224
-
Selective ectodomain phosphorylation and regulated cleavage of β-amyloid precursor protein
-
(1994)
EMBO J
, vol.13
, pp. 534-542
-
-
Hung, A.Y.1
Selkoe, D.J.2
-
67
-
-
0033382226
-
Identification of a novel aspartic protease (Asp 2) as beta-secretase
-
(1999)
Mol Cell Neurosci
, vol.14
, pp. 419-427
-
-
Hussain, I.1
Powell, D.2
Howlett, D.R.3
Tew, D.G.4
Meek, T.D.5
Chapman, C.6
Gloger, I.S.7
Murphy, K.E.8
Southan, C.D.9
Ryan, D.M.10
Smith, T.S.11
Simmons, D.L.12
Walsh, F.S.13
Dingwall, C.14
Christie, G.15
-
68
-
-
0032543684
-
Association of missense and 5′-splice-site mutations in tau with the inherited FTDP-17
-
(1998)
Nature
, vol.393
, pp. 702-705
-
-
Hutton, M.1
Lendon, C.2
Rizzu, P.3
Baker, M.4
Froelich, S.5
Houlden, H.6
Pickering-Brown, S.7
Chakraverty, S.8
Isaacs, A.9
Grover, A.10
Hackett, J.11
Adamson, J.12
Lincoln, S.13
Dickson, D.14
Davies, P.15
Peterson, R.16
Stevens, M.17
De Graaff, E.18
Wauters, E.19
Van Baren, J.20
Hillebrand, M.21
Joosse, M.22
Kwon, J.23
Nowotny, P.24
Che, L.25
Norton, J.26
Morris, J.27
Ree, L.28
Trojanowski, J.29
Basun, H.30
Lannfelt, L.31
Neystat, M.32
Fahn, S.33
Dark, F.34
Tannenberg, T.35
Dodd, P.36
Hayward, N.37
Kowk, J.38
Schofield, P.39
Andreadis, A.40
Snowden, J.41
Craufurd, D.42
Neary, D.43
Owen, F.44
Oostra, B.45
Hardy, J.46
Goate, A.47
Van Swieten48
Mann, D.49
Lynch, T.50
Hutink, P.51
more..
-
69
-
-
17044461433
-
The endogenous and cell cycle-dependent phosphorylation of tau protein in living cells: Implications for Alzheimer's disease
-
(1998)
Mol Biol Cell
, vol.9
, pp. 1495-1512
-
-
Illenberger, S.1
Zheng-Fischhofer, Q.2
Preuss, U.3
Stamer, K.4
Baumann, K.5
Trinczek, B.6
Biernat, J.7
Godemann, R.8
Mandelkow, E.M.9
Mandelkow, E.10
-
76
-
-
0023105114
-
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
-
(1987)
Nature
, vol.325
, pp. 733-736
-
-
Kang, J.1
Lemaire, H.G.2
Unterberck, A.3
Salbaum, J.M.4
Msters, C.L.5
Grzeschik, K.-H.6
Multhaup, G.7
Beyreuther, K.8
Muller-Hill, B.9
-
80
-
-
0025056563
-
Precursor of amyloid protein in Alzheimer's disease undergoes fast anterograde axonal transport
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 1561-1565
-
-
Koo, E.H.1
Sisodia, S.S.2
Archer, D.A.3
Martin, L.J.4
Weidemann, A.5
Beyreuther, K.6
Masters, C.L.7
Fischer, P.8
Price, D.L.9
-
81
-
-
0028276801
-
Evidence that production and release of amyloid β-protein involves the endocytic pathway
-
(1994)
J Biol Chem
, vol.269
, pp. 17386-17389
-
-
Koo, E.H.1
Squazzo, S.2
-
85
-
-
13344282063
-
Alzheimer-associated presenilins 1 and 2: Neuronal expression in brain and localization to intracellular membranes in mammalian cells
-
(1996)
Nature Med
, vol.2
, pp. 224-229
-
-
Kovacs, D.M.1
Fausett, H.J.2
Page, K.J.3
Kim, T.-W.4
Mori, R.D.5
Merriam, D.E.6
Hollister, R.D.7
Hallmark, O.G.8
Mancini, R.9
Felsenstein, K.M.10
Hyman, B.T.11
Tanzi, R.E.12
Wasco, W.13
-
87
-
-
11544279355
-
1-42 are potent central nervous system neurotoxins
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
Edwards, C.4
Freed, R.5
Iosatos, M.6
Morgan, T.E.7
Rozovsky, I.8
Trommer, B.9
Viola, K.L.10
Wals, P.11
Zhang, C.12
Finch, C.E.13
Krafft, G.A.14
Klein, W.L.15
-
91
-
-
16044365171
-
The E280A presenilin 1 Alzheimer mutation produces increased Aβ42 deposition and severe cerebellar pathology
-
(1996)
Nature Med
, vol.2
, pp. 1146-1150
-
-
Lemere, C.A.1
Lopera, F.2
Kosik, K.S.3
Lendon, C.L.4
Ossa, J.5
Saido, T.C.6
Yamaguchi, H.7
Ruiz, A.8
Martinez, A.9
Madrigal, L.10
Hingcapie, L.11
Arango, L.J.C.12
Anthony, D.C.13
Koo, E.H.14
Goate, A.M.15
Selkoe, D.J.16
Arango, V.J.C.17
-
92
-
-
0029906585
-
Assessment of normal and mutant human presenilin function in Caenorhabditis elegans
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 14940-14944
-
-
Levitan, D.1
Doyle, T.G.2
Brousseau, D.3
Lee, M.K.4
Thinakaran, G.5
Slunt, H.H.6
Sisodia, S.S.7
Greenwald, I.8
-
93
-
-
0029116848
-
Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene
-
(1995)
Nature
, vol.377
, pp. 351-354
-
-
Levitan, D.1
Greenwald, I.2
-
94
-
-
0025296269
-
Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch-type
-
(1990)
Science
, vol.248
, pp. 1124-1126
-
-
Levy, E.1
Carman, M.D.2
Fernandez-Madrid, I.J.3
Power, M.D.4
Lieberburg, I.5
Van Duinen, S.C.6
Bots, G.T.A.M.7
Luyendijk, W.8
Frangione, B.9
-
95
-
-
0029087026
-
Candidate gene for the chromosome 1 familial Alzheimer's disease locus
-
(1995)
Science
, vol.269
, pp. 973-977
-
-
Levy-Lahad, E.1
Wasco, W.2
Poorkaj, P.3
Romano, D.M.4
Oshima, J.5
Pettingell, H.6
Yu, C.7
Jondro, P.D.8
Schmidt, S.D.9
Wang, K.10
Crowley, A.C.11
Fu, Y.-H.12
Guentette, S.Y.13
Galas, D.14
Nemens, E.15
Wijsman, E.M.16
Bird, T.D.17
Schellenberg, G.D.18
Tanzi, R.E.19
-
97
-
-
0034621824
-
Photoactivated γ-secretase inhibitors directed to the active site covalently label presenilin 1
-
(2000)
Nature
, vol.405
, pp. 689-694
-
-
Li, Y.-M.1
Xu, M.2
Lai, M.-T.3
-
101
-
-
9444276544
-
Amyloid beta protein (A-beta) deposition in chromosome 14-linked Alzheimer's disease: Predominance of A-beta [42(43)]
-
(1996)
Ann Neurol
, vol.40
, pp. 149-156
-
-
Mann, D.M.A.1
Iwatsubo, T.2
Cairns, N.J.3
Lantos, P.L.4
Nochlin, D.5
Sumi, S.M.6
Bird, T.D.7
Poorkaj, P.8
Hardy, J.9
Hutton, M.10
Prihar, G.11
Crook, R.12
Rossor, M.N.13
Haltia, M.14
-
106
-
-
0029610011
-
The inflammatory response system of brain: Implications for therapy of Alzheimer and other neurodegenerative diseases
-
(1995)
Brain Res Rev
, vol.21
, pp. 195-218
-
-
McGeer, P.L.1
McGeer, E.G.2
-
107
-
-
0028982454
-
Reduction of beta-amyloid peptide 42 in the cerebrospinal fluid of patients with Alzheimer's disease
-
(1995)
Ann Neurol
, vol.38
, pp. 643-648
-
-
Motter, R.1
Vigo-Pelfrey, C.2
Kholodenko, D.3
Barbour, R.4
Johnson- Wood, K.5
Galasko, D.6
Chang, L.7
Miller, B.8
Clark, C.9
Green, R.10
Olson, D.11
Southwick, P.12
Wolfert, R.13
Munroe, B.14
Lieberburg, I.15
Seubert, P.16
Schenk, D.17
-
108
-
-
0032587839
-
2-macroglobulin with Alzheimer's disease in a Finnish elderly population
-
(1999)
Ann Neurol
, vol.46
, pp. 382-390
-
-
Myllykangas, L.1
Polvikoski, T.2
Sulkava, R.3
Verkkoniemi, A.4
Crook, R.5
Tienari, P.J.6
Pusa, A.K.7
Niinisto, L.8
O'Brien, P.9
Kontula, K.10
Hardy, J.11
Haltia, M.12
Perez-Tur, J.13
-
110
-
-
0000138540
-
Effects of PS1 deficiency on membrane protein trafficking in neurons
-
(1998)
Neuron
, vol.21
, pp. 1213-1221
-
-
Naruse, S.1
Thinakaran, G.2
Luo, J.J.3
Kusiak, W.4
Tomita, T.5
Iwatsubo, T.6
Qian, X.7
Ginty, D.D.8
Price, D.L.9
Borchelt, D.R.10
Wong, P.C.11
Sisodia, S.S.12
-
113
-
-
0022723508
-
One of the antigenic determinants of paired helical filaments is related to tau protein
-
(1986)
J Biochem
, vol.99
, pp. 1541-1544
-
-
Nukina, N.1
Ihara, Y.2
-
118
-
-
0033516554
-
Mutagenesis identifies new signals for β-amyloid precursor protein endotycosis, turnover and the generation of secreted fragments, including A42
-
(1999)
J Biol Chem
, vol.274
, pp. 18851-18856
-
-
Perez, R.G.1
Soriano, S.2
Hayes, J.D.3
Ostaszewski, B.L.4
Xia, W.5
Selkoe, D.J.6
Chen, X.7
Stokin, G.B.8
Koo, E.H.9
-
121
-
-
0030889220
-
299 and occur as stable N- and C-terminal fragments in normal and Alzheimer brain tissue
-
(1997)
Neurobiol Dis
, vol.3
, pp. 325-337
-
-
Podlisny, M.B.1
Citron, M.2
Amarante, P.3
Sherrington, R.4
Xia, W.5
Zhang, J.6
Diehl, T.7
Levesque, G.8
Fraser, P.9
Haass, C.10
Koo, E.H.M.11
Seubert, P.12
St. George-Hyslop, P.13
Teplow, D.B.14
Selkoe, D.J.15
-
124
-
-
0028841027
-
Apolipoprotein E, dementia, and cortical deposition of β-amyloid protein
-
(1995)
N Engl J Med
, vol.333
, pp. 1242-1247
-
-
Polvikoski, T.1
Sulkava, R.2
Haltia, M.3
Kainulainen, K.4
Vuorio, A.5
Verkkoniemi, A.6
Niinisto, L.7
Halonen, P.8
Kontula, K.9
-
127
-
-
0032032847
-
Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates Aβ1-42/43 expression
-
(1998)
Neuron
, vol.20
, pp. 611-617
-
-
Qian, S.1
Jiang, P.2
Guan, X.M.3
Singh, G.4
Trambauer, M.E.5
Yu, H.6
Chen, H.Y.7
Van de Ploeg, L.H.8
Zheng, H.9
-
130
-
-
0033579505
-
Cell surface presenilin-1 participates in the gamma-secretase-like proteolysis of notch
-
(1999)
J Biol Chem
, vol.274
, pp. 36801-36807
-
-
Ray, W.J.1
Yao, M.2
Mumm, J.3
Schroeter, E.H.4
Saftig, P.5
Wolfe, M.6
Selkoe, D.J.7
Kopan, R.8
Goate, A.M.9
-
131
-
-
0033014046
-
Evidence for a physical interaction between presenilin and Notch
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 3263-3268
-
-
Ray, W.J.1
Yao, M.2
Nowotny, P.3
Mumm, J.4
Zhang, W.5
Wu, J.Y.6
Kopan, R.7
Goate, A.M.8
-
133
-
-
0026447529
-
Complement activation by β-amyloid in Alzheimer disease
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10016-10020
-
-
Rogers, J.1
Cooper, N.R.2
Webster, S.3
Schultz, J.4
McGeer, P.L.5
Styren, S.D.6
Civin, W.H.7
Brachova, L.8
Bradt, B.9
Ward, P.10
Lieberburg, I.11
-
134
-
-
0030250567
-
Inflammation and Alzheimer's disease pathogenesis
-
(1996)
Neurobiol Aging
, vol.17
, pp. 681-686
-
-
Rogers, J.1
Webster, S.2
Lue, L.-F.3
Brachova, L.4
Civin, W.H.5
Emmerling, M.6
Shivers, B.7
Walker, D.8
McGeer, P.9
-
136
-
-
0033979472
-
The deletion polymorphism and Val1000lle in alpha-2-macroglobulin and Alzheimer disease in Caribbean Hispanics
-
(2000)
Neurosci Lett
, vol.279
, pp. 133-136
-
-
Romas, S.N.1
Mayeux, R.2
Rabinowitz, D.3
Tang, M.X.4
Zadroga, H.R.5
Lantigua, R.6
Medrano, M.7
Tycko, B.8
Knowles, J.A.9
-
139
-
-
0024395366
-
Secreted form of amyloid β protein precursor is involved in the growth regulation of fibroblasts
-
(1989)
Cell
, vol.58
, pp. 615-622
-
-
Saitoh, T.1
Sunsdmo, M.2
Roch, J.M.3
Kimura, N.4
Cole, G.5
Schubert, D.6
Oltersdorf, T.7
Schenk, D.B.8
-
141
-
-
0027327267
-
Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease
-
(1993)
Neurology
, vol.43
, pp. 1467-1472
-
-
Saunders, A.M.1
Strittmatter, W.J.2
Schmechel, D.3
George-Hyslop, P.H.4
Pericak-Vance, M.A.5
Joo, S.H.6
Rosi, B.L.7
Gusella, J.F.8
Crapper-Machlachlan, D.R.9
Alberts, M.J.10
Hulette, C.11
Crain, B.12
Goldgaber, D.13
Roses, A.D.14
-
142
-
-
0026471656
-
Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14
-
(1992)
Science
, vol.258
, pp. 668-671
-
-
Schellenberg, G.D.1
Bird, T.D.2
Wijsman, E.M.3
Orr, H.T.4
Anderson, L.5
Nemens, E.6
White, J.A.7
Bonnycastle, L.8
Weber, J.L.9
Alonso, M.E.10
Potter, H.11
Heston, L.H.12
Martin, G.M.13
-
143
-
-
0033536163
-
Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse
-
(1999)
Nature
, vol.400
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
Gordon, G.4
Grajeda, H.5
Guido, T.6
Hu, K.7
Huang, J.8
Johnson-Wood, K.9
Khan, K.10
Kholodenko, D.11
Lee, M.12
Liao, Z.13
Lieberburg, I.14
Motter, R.15
Mutter, L.16
Soriano, F.17
Shopp, G.18
Vasquez, N.19
Vendevert, C.20
Wogulis, S.M.21
Yednock, T.22
Games, D.23
Suebert, P.24
more..
-
144
-
-
16044373524
-
Secreted amyloid β-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
-
(1996)
Nature Med
, vol.2
, pp. 864-870
-
-
Scheuner, D.1
Eckman, C.2
Jensen, M.3
Song, X.4
Citron, M.5
Suzuki, N.6
Bird, T.D.7
Hardy, J.8
Hutton, M.9
Kukull, W.10
Larson, E.11
Levy-Lahad, E.12
Viitanen, M.13
Peskind, E.14
Poorkaj, P.15
Schellenberg, G.16
Tanzi, R.17
Wasco, W.18
Lannfelt, L.19
Delkoe, D.J.20
Younkin, S.21
more..
-
145
-
-
0027365822
-
Increased amyloid β-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 9649-9653
-
-
Schmechel, D.E.1
Saunders, A.M.2
Strittmatter, W.J.3
Crain, B.J.4
Hulette, C.M.5
Joo, S.H.6
Pericak-Vance, M.7
Goldgaber, D.8
Roses, A.D.9
-
148
-
-
0033529331
-
Endogenous presenilin 1 redistributes to the surface of lamellipodia upon adhesion of Jurkat cells to a collagen matrix
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 7932-7937
-
-
Schwarzman, A.L.1
Singh, N.2
Tsiper, M.3
Gregori, L.4
Dranovsky, A.5
Vitek, M.P.6
Glabe, C.G.7
St. George-Hyslop, P.H.8
Goldgaber, D.9
-
149
-
-
0031038918
-
Alzheimer's disease: Genotypes, phenotype, and treatments
-
(1997)
Science
, vol.275
, pp. 630-631
-
-
Selkoe, D.J.1
-
150
-
-
0033600274
-
Translating cell biology into therapeutic advances in Alzheimer's disease
-
(1999)
Nature
, vol.399
-
-
Selkoe, D.J.1
-
154
-
-
0027459686
-
Secretion of β-amyloid precursor protein cleaved at the aminoterminus of the β-amyloid peptide
-
(1993)
Nature
, vol.361
, pp. 260-263
-
-
Seubert, P.1
Oltersdorf, T.2
Lee, M.G.3
Barbour, R.4
Blomqist5
Davis, D.L.6
Bryant, K.7
Fritz, L.C.8
Galasko, D.9
Thai, L.J.10
Lieberburg, I.11
Schenk, D.B.12
-
155
-
-
0026646605
-
Isolation and quantitation of soluble Alzheimer's β-peptide from biological fluids
-
(1992)
Nature
, vol.359
, pp. 325-327
-
-
Seubert, P.1
Vigo-Pelfrey, C.2
Esch, F.3
Lee, M.4
Dovey, H.5
Davis, D.6
Sinha, S.7
Schlossmacher, M.G.8
Whaley, J.9
Swindlehurst, C.10
McCormack, R.11
Wolfert, R.12
Selkoe, D.J.13
Lieberburg, I.14
Schenk, D.15
-
157
-
-
0029004341
-
Cloning of a novel gene bearing missense mutations in early onset familial Alzheimer disease
-
(1995)
Nature
, vol.375
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
Rogaeva, E.A.4
Levesque, G.5
Ikeda, M.6
Chi, H.7
Lin, C.8
Li, G.9
Holman, K.10
Tsuda, T.11
Mar, L.12
Foncin, J.-F.13
Bruni, A.C.14
Montesi, M.P.15
Sorbi, S.16
Rainero, I.17
Pinessi, L.18
Nee, L.19
Chumakov, I.20
Pollen, D.A.21
Roses, A.D.22
Fraser, P.E.23
Rommens, J.M.24
St. George-Hyslop, P.H.25
more..
-
158
-
-
0026760261
-
Production of the Alzheimer amyloid β protein by normal proteolytic processing
-
(1992)
Science
, vol.258
, pp. 126-129
-
-
Shoji, M.1
Golde, T.E.2
Ghiso, J.3
Cheung, T.T.4
Estus, S.5
Shaffer, L.M.6
Cai, X.7
McKay, D.M.8
Tintner, R.9
Frangione, B.10
Younkin, S.G.11
-
160
-
-
0033518251
-
Purification and cloning of amyloid precursor protein beta-secretase from human brain
-
(1999)
Nature
, vol.402
, pp. 537-540
-
-
Sinha, S.1
Anderson, J.P.2
Barbour, R.3
Basi, G.S.4
Caccavello, R.5
Davis, D.6
Doan, M.7
Dovey, H.F.8
Frigon, N.9
Hong, J.10
Jacobson-Croak, K.11
Jewett, N.12
Keim, P.13
Knops, J.14
Lieberburg, I.15
Power, M.16
Tan, H.17
Tatsuno, G.18
Tung, J.19
Schenk, D.20
Seubert, P.21
Suomensaari, S.M.22
Wang, S.23
Walker, D.24
John, V.25
more..
-
161
-
-
0025297453
-
The protease inhibitory properties of the Alzheimer's β-amyloid precursor protein
-
(1990)
J Biol Chem
, vol.265
, pp. 8983-8985
-
-
Sinha, S.1
Dovey, H.F.2
Seubert, P.3
Ward, P.J.4
Balcher, R.W.5
Blaber, M.6
Bradshaw, R.A.7
Arici, M.8
Mobley, W.C.9
Lieberburg, I.10
-
168
-
-
0033610863
-
Expression of Alzheimer's disease-associated presenilin-1 is controlled by proteolytic degradation and complex formation
-
(1998)
J Biol Chem
, vol.273
, pp. 32322-32331
-
-
Steiner, H.1
Capell, A.2
Pesold, B.3
Citron, M.4
Kloetzek, P.M.5
Selkoe, D.J.6
Romig, H.7
Mandla, K.8
Haass, C.9
-
169
-
-
0033517844
-
Amyloidogenic function of the Alzheimer's disease-associated presenilin 1 in the absence of endoproteolysis
-
(1999)
Biochemistry
, vol.38
, pp. 14600-14605
-
-
Steiner, H.1
Romig, H.2
Pesold, B.3
Philipp, U.4
Baader, M.5
Citron, M.6
Loetscher, H.7
Jacobsen, H.8
Haass, C.9
-
171
-
-
0033639117
-
Requirements for presenilin-dependent cleavage of notch and other transmembrane proteins
-
(2000)
Mol Cell
, vol.6
, pp. 625-636
-
-
Struhl, G.1
Adachi, A.2
-
177
-
-
15844425969
-
Endoprotreolysis of presenilin 1 and accumulation of processed derivatives in vivo
-
(1996)
Neuron
, vol.17
, pp. 181-190
-
-
Thinakaran, G.1
Borchelt, D.R.2
Lee, M.K.3
Slunt, H.H.4
Spitzer, L.5
Kim, G.6
Ratovitsky, T.7
Davenport, F.8
Nordstedt, C.9
Seeger, M.10
Hardy, J.11
Levey, A.I.12
Gandy, S.E.13
Jenkins, N.A.14
Copeland, N.G.15
Price, D.L.16
Sisodia, S.S.17
-
178
-
-
0030667426
-
Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors
-
(1997)
J Biol Chem
, vol.272
, pp. 28415-28422
-
-
Thinakaran, G.1
Harris, C.L.2
Ratovitski, T.3
Davenport, F.4
Slunt, H.H.5
Price, D.L.6
Borchelt, D.R.7
Sisodia, S.S.8
-
182
-
-
12644258498
-
The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid β protein ending at the 42nd (or 43rd) residue
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 2025-2030
-
-
Tomita, T.1
Maruyama, K.2
Saido, T.C.3
Kume, H.4
Shinozaki, K.5
Tokuhiro, S.6
Capell, A.7
Walter, J.8
Grunberg, J.9
Haass, C.10
Iwatsubo, T.11
Obata, K.12
-
184
-
-
0029569152
-
Phosphorylation of paired helical filament tau in Alzheimer's disease neurofibrillary lesions: Focusing on phosphatases
-
(1995)
FASEB J
, vol.9
, pp. 1570-1576
-
-
Trojanowski, J.Q.1
Lee, V.M.2
-
185
-
-
0033595706
-
Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
-
(1999)
Science
, vol.286
, pp. 735-741
-
-
Vassar, R.1
Bennett, B.D.2
Babu-Khan, S.3
Khan, S.4
Mendiaz, E.A.5
Denis, P.6
Teplow, D.B.7
Ross, S.8
Amarante, P.9
Loeloff, R.10
Luo, Y.11
Fisher, S.12
Fuller, J.13
Edenson, S.14
Lile, J.15
Jarosinski, M.A.16
Biere, A.L.17
Curran, E.18
Burgess, T.19
Louis, J.C.20
Collins, F.21
Treanor, J.22
Rogers, G.23
Citron, M.24
more..
-
189
-
-
0031030058
-
Ectodomain phosphorylation of β-amyloid precursor protein at two distinct cellular locations
-
(1997)
J Biol Chem
, vol.272
, pp. 1896-1903
-
-
Walter, J.1
Capell, A.2
Hung, A.Y.3
Langen, H.4
Schnolzer, M.5
Thinkaran, G.6
Sisodia, S.S.7
Selkoe, D.J.8
Haass, C.9
-
191
-
-
0024550204
-
Identification, biogenesis and localization of precursors of Alzheimer's disease A4 amyloid protein
-
(1989)
Cell
, vol.57
, pp. 115-126
-
-
Weidemann, A.1
Konig, G.2
Bunke, D.3
Fischer, P.4
Salbaum, J.M.5
Masters, C.L.6
Beyreuther, K.7
-
193
-
-
0003986552
-
Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer's disease
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 4506-4510
-
-
Wischik, C.M.1
Novak, M.2
Thogersen, H.C.3
Edwards, P.C.4
Runswick, M.J.5
Jakes, R.6
Walker, J.E.7
Milstein, C.8
Rother, M.9
Klug, A.10
-
195
-
-
0033551099
-
Peptidomimetic probes and molecular modeling suggest Alzheimer's γ-secretase is an intramembrane-cleaving aspartyl protease
-
(1999)
Biochemistry
, vol.38
, pp. 4720-4727
-
-
Wolfe, M.S.1
Xia, W.2
Moore, C.L.3
Leatherwood, D.D.4
Ostaszewski, B.L.5
Rahmati, T.6
Donkor, I.O.7
Selkoe, D.J.8
-
197
-
-
10544224542
-
Participation of presenilin 2 in apoptosis: Enhanced basal activity conferred by an Alzheimer mutation
-
(1996)
Science
, vol.274
, pp. 1710-1713
-
-
Wolozin, B.1
Iwasaki, K.2
Vito, P.3
Ganjei, J.K.4
Lacana, E.5
Sunderland, T.6
Zhao, B.7
Kusiak, J.W.8
Wasco, W.9
D'Adamio, L.10
-
198
-
-
17744401440
-
Presenilin 1 is required for Notch 1 and D111 expression in the paraxial mesoderm
-
(1997)
Nature
, vol.397
, pp. 288
-
-
Wong, P.1
Zhen, H.2
Chen, H.3
Becher, M.W.4
Sirinathsighji, D.J.5
Trumbauer, M.E.6
Proce, D.L.7
Van der Ploeg, L.H.T.8
Sisodia, S.S.9
-
201
-
-
0034255029
-
Presenilin complexes with the C-terminal fragments of amyloid precursor protein at the sites of amyloid β-protein generation
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 9299-9304
-
-
Xia, W.1
Ray, W.J.2
Ostaszewski, B.L.3
Rahmati, T.4
Kimberly, W.T.5
Wolfe, M.S.6
Zhang, J.7
Goate, A.M.8
Selkoe, D.J.9
-
202
-
-
16944365745
-
Enhanced production and oligomerization of the 42-residue amyloid β-protein by Chinese hamster ovary cells stably expressing mutant presenilins
-
(1997)
J Biol Chem
, vol.272
, pp. 7977-7982
-
-
Xia, W.1
Zhang, J.2
Kholodenko, D.3
Citron, M.4
Podlisny, M.B.5
Teplow, D.B.6
Haass, C.7
Seubert, P.8
Koo, E.H.9
Selkoe, D.J.10
-
203
-
-
0032564388
-
Presenilin 1 regulates the processing APP C-terminal fragments and the generation of amyloid β-protein in ER and Golgi
-
(1998)
Biochemistry
, vol.37
, pp. 16465-16471
-
-
Xia, W.1
Zhang, J.2
Ostaszewski, B.L.3
Kimberly, W.T.4
Seubert, P.5
Koo, E.H.6
Shen, J.7
Selkoe, D.J.8
-
208
-
-
0033518264
-
Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity
-
(1999)
Nature
, vol.402
, pp. 533-537
-
-
Yan, R.1
Bienkowski, M.J.2
Shuck, M.E.3
Miao, H.4
Tory, M.C.5
Pauley, A.M.6
Brashier, J.R.7
Stratman, N.C.8
Mathews, W.R.9
Buhl, A.E.10
Carter, D.B.11
Tomasselli, A.G.12
Parodi, L.A.13
Heinrikson, R.L.14
Gurney, M.E.15
-
209
-
-
0013615899
-
RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease
-
(1996)
Nature
, vol.382
, pp. 685-691
-
-
Yan, S.D.1
Chen, X.2
Fu, J.3
Chen, M.4
Zhu, H.5
Roher, A.6
Slattery, T.7
Zhao, L.8
Nagashima, M.9
Morser, J.10
Migheli, A.11
Nawroth, P.12
Stern, D.13
Schmidt, A.M.14
-
210
-
-
0032440973
-
Characterization of Drosophila Presenilin and its colocalization with Notch during development
-
(1998)
Mech Dev
, vol.79
, pp. 199-211
-
-
Ye, Y.1
Fortini, M.E.2
-
212
-
-
0032568821
-
The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin
-
(1998)
J Biol Chem
, vol.273
, pp. 16470-16475
-
-
Yu, G.1
Chen, F.2
Levesque, G.3
Nishimura, M.4
Zhang, D.M.5
Levesque, L.6
Rogaeva, E.7
Xu, D.8
Liang, Y.9
Duthie, M.10
St. George-Hyslop, P.H.11
Fraser, P.E.12
-
214
-
-
0028988801
-
β-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity
-
(1995)
Cell
, vol.81
, pp. 525-531
-
-
Zheng, H.1
Jiang, M.2
Trumbauer, M.E.3
Sirinathsinghji, D.J.S.4
Hopkins, R.5
Smith, D.W.6
Heavesn, R.P.7
Dawson, G.R.8
Boyce, S.9
Conner, M.W.10
Stevens, K.A.11
Slunt, H.H.12
Sisodia, S.S.13
Chen, H.Y.14
Van der Ploeg, L.H.T.15
-
216
-
-
0030604067
-
Cerebrovascular transport of Alzheimer's amyloid beta and apolipoproteins J and E: Possible anti-amyloidogenic role of the blood-brain barrier
-
(1996)
Life Sci
, vol.59
, pp. 1483-1497
-
-
Zlokovic, B.V.1
|