-
1
-
-
27644589675
-
The diverse functions of histone lysine methylation
-
Martin, C. & Zhang, Y. The diverse functions of histone lysine methylation. Nature Rev. Mol. Cell Biol. 6, 838-849 (2005).
-
(2005)
Nature Rev. Mol. Cell Biol.
, vol.6
, pp. 838-849
-
-
Martin, C.1
Zhang, Y.2
-
2
-
-
23044431656
-
Histone H3 lysine 9 methylation and HP1γ are associated with transcription elongation through mammalian chromatin
-
Vakoc, C. R., Mandat, S. A., Olenchock, B. A. & Blobel, G. A. Histone H3 lysine 9 methylation and HP1γ are associated with transcription elongation through mammalian chromatin. Mol. Cell 19, 381-391 (2005).
-
(2005)
Mol. Cell
, vol.19
, pp. 381-391
-
-
Vakoc, C.R.1
Mandat, S.A.2
Olenchock, B.A.3
Blobel, G.A.4
-
3
-
-
27744577727
-
Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription
-
Carrozza, M. J. et al. Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription. Cell 123, 581-592 (2005).
-
(2005)
Cell
, vol.123
, pp. 581-592
-
-
Carrozza, M.J.1
-
4
-
-
0035282458
-
Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromodomain
-
Bannister, A. J. et al. Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromodomain. Nature 410, 120-124 (2001).
-
(2001)
Nature
, vol.410
, pp. 120-124
-
-
Bannister, A.J.1
-
5
-
-
0035282573
-
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
-
Lachner, M., O'Carroll, D., Rea, S., Mechtler, K. & Jenuwein, T. Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature 410, 116-120 (2001).
-
(2001)
Nature
, vol.410
, pp. 116-120
-
-
Lachner, M.1
O'Carroll, D.2
Rea, S.3
Mechtler, K.4
Jenuwein, T.5
-
6
-
-
33745839365
-
A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling
-
Wysocka, J. et al. A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling. Nature 442, 91-95 (2006).
-
(2006)
Nature
, vol.442
, pp. 91-95
-
-
Wysocka, J.1
-
7
-
-
5044228483
-
Human PAD4 regulates histone arginine methylation levels via demethylimination
-
Wang, Y. et al. Human PAD4 regulates histone arginine methylation levels via demethylimination. Science 306, 279-283 (2004).
-
(2004)
Science
, vol.306
, pp. 279-283
-
-
Wang, Y.1
-
8
-
-
4444372638
-
Histone deimination antagonizes arginine methylation
-
Cuthbert, G. L. et al. Histone deimination antagonizes arginine methylation. Cell 118, 545-553 (2004). References 7 and 8 identify PADI4 as the first enzyme capable of antagonizing histone arginine methylation.
-
(2004)
Cell
, vol.118
, pp. 545-553
-
-
Cuthbert, G.L.1
-
9
-
-
11144332565
-
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
-
Shi, Y. et al. Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 119, 941-953 (2004). Identifies the first true histone demethylase enzyme, LSD1, which utilizes flavin as a cofactor to carry out an oxidative demethylation reaction.
-
(2004)
Cell
, vol.119
, pp. 941-953
-
-
Shi, Y.1
-
10
-
-
24144462170
-
LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription
-
Metzger, E. et al. LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription. Nature 437, 436-439 (2005).
-
(2005)
Nature
, vol.437
, pp. 436-439
-
-
Metzger, E.1
-
11
-
-
25144519737
-
An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation
-
Lee, M. G., Wynder, C., Cooch, N. & Shiekhattar, R. An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation. Nature 437, 432-435 (2005).
-
(2005)
Nature
, vol.437
, pp. 432-435
-
-
Lee, M.G.1
Wynder, C.2
Cooch, N.3
Shiekhattar, R.4
-
12
-
-
24944535335
-
Regulation of LSD1 histone demethylase activity by its associated factors
-
Shi, Y. J. et al. Regulation of LSD1 histone demethylase activity by its associated factors. Mol. Cell 19, 857-864 (2005).
-
(2005)
Mol. Cell
, vol.19
, pp. 857-864
-
-
Shi, Y.J.1
-
13
-
-
32844454603
-
Histone demethylation by a family of JmjC-domain-containing proteins
-
Tsukada, Y. et al. Histone demethylation by a family of JmjC-domain-containing proteins. Nature 439, 811-816 (2006). The authors used a novel in vitro histone demethylase assay to biochemically purify and characterize the first JmjC-domain-containing histone demethylase enzyme.
-
(2006)
Nature
, vol.439
, pp. 811-816
-
-
Tsukada, Y.1
-
14
-
-
33646138230
-
JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor
-
Yamane, K. et al. JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor. Cell 125, 483-495 (2006). The authors biochemically purified a novel JmjC-domain-containing histone H3K9 demethylase and demonstrated its role in androgen receptor-mediated gene activation.
-
(2006)
Cell
, vol.125
, pp. 483-495
-
-
Yamane, K.1
-
15
-
-
33646124469
-
Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases
-
Whetstine, J. R. et al. Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases. Cell 125, 467-481 (2006).
-
(2006)
Cell
, vol.125
, pp. 467-481
-
-
Whetstine, J.R.1
-
16
-
-
33745847680
-
The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and 36
-
Klose, R. et al. The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and 36. Nature 442, 312-316 (2006).
-
(2006)
Nature
, vol.442
, pp. 312-316
-
-
Klose, R.1
-
17
-
-
33746332412
-
The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3
-
Cloos, P. A. et al. The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3. Nature 442, 307-311 (2006).
-
(2006)
Nature
, vol.442
, pp. 307-311
-
-
Cloos, P.A.1
-
18
-
-
33745146571
-
Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells
-
Fodor, B. D. et al. Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells. Genes Dev. 20, 1557-1562 (2006). References 15 to 18 demonstrate that the JHDM3/JMJD2 histone demethylase enzymes are capable of removing the trimethyl modification state.
-
(2006)
Genes Dev.
, vol.20
, pp. 1557-1562
-
-
Fodor, B.D.1
-
19
-
-
0035150397
-
JmjC: Cupin metalloenzyme-like domains in jumonji, hairless and phospholipase A2β
-
Clissold, P. M. & Ponting, C. P. JmjC: cupin metalloenzyme-like domains in jumonji, hairless and phospholipase A2β. Trends Biochem. Sci. 26, 7-9 (2001). The authors identify bioinformatic and structural similarities between metalloenzymes and JmjC-domain-containing proteins.
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 7-9
-
-
Clissold, P.M.1
Ponting, C.P.2
-
20
-
-
0029004775
-
Gene trap capture of a novel mouse gene, jumonji, required for neural tube formation
-
Takeuchi, T. et al. Gene trap capture of a novel mouse gene, jumonji, required for neural tube formation. Genes Dev. 9, 1211-1222 (1995). The authors cloned the Jumonji protein in a gene-trap screen for factors involved in neural tube formation. The JmjC domain was later named on the basis of its presence in the Jumonji protein.
-
(1995)
Genes Dev.
, vol.9
, pp. 1211-1222
-
-
Takeuchi, T.1
-
21
-
-
0034212377
-
Evidence of domain swapping within the Jumonji family of transcription factors
-
Balciunas, D. & Ronne, H. Evidence of domain swapping within the Jumonji family of transcription factors. Trends Biochem. Sci. 25, 274-276 (2000).
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 274-276
-
-
Balciunas, D.1
Ronne, H.2
-
22
-
-
0031888149
-
Microbial relatives of seed storage proteins: Conservation of motifs in a functionally diverse superfamily of enzymes
-
Dunwell, J. M. & Gane, P. J. Microbial relatives of seed storage proteins: conservation of motifs in a functionally diverse superfamily of enzymes. J. Mol. Evol. 46, 147-154 (1998).
-
(1998)
J. Mol. Evol.
, vol.46
, pp. 147-154
-
-
Dunwell, J.M.1
Gane, P.J.2
-
23
-
-
0037097861
-
FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor
-
Lando, D. et al. FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. Genes Dev. 16, 1466-1471 (2002). The authors identify the JmjC-domain-containing protein FIH as an asparaginyl hydroxylase enzyme and for the first time demonstrate enzymatic activity for a mammalian JmjC-domain protein.
-
(2002)
Genes Dev.
, vol.16
, pp. 1466-1471
-
-
Lando, D.1
-
24
-
-
17644392469
-
Methylation: Lost in hydroxylation?
-
Trewick, S. C., McLaughlin, P. J. & Allshire, R. C. Methylation: lost in hydroxylation? EMBO Rep. 6, 315-320 (2005). The authors propose that JmjC-domain-containing proteins might function as histone demethylases based on the function of the fission yeast JmjC-domain protein Epe1 in regulating silent chromatin structure.
-
(2005)
EMBO Rep.
, vol.6
, pp. 315-320
-
-
Trewick, S.C.1
McLaughlin, P.J.2
Allshire, R.C.3
-
25
-
-
0037180452
-
Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway
-
Dann, C. E., Bruick, R. K. & Deisenhofer, J. Structure of factor-inhibiting hypoxia-inducible factor 1: an asparaginyl hydroxylase involved in the hypoxic response pathway. Proc. Natl Acad. Sci. USA 99, 15351-15356 (2002).
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 15351-15356
-
-
Dann, C.E.1
Bruick, R.K.2
Deisenhofer, J.3
-
26
-
-
0037449811
-
Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF1α
-
Elkins, J. M. et al. Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF1α. J. Biol. Chem. 278, 1802-1806 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 1802-1806
-
-
Elkins, J.M.1
-
27
-
-
0037470162
-
Structure of human FIH-1 reveals a unique active site pocket and interaction sites for HIF-1 and von Hippel-Lindau
-
Lee, C., Kim, S. J., Jeong, D. G., Lee, S. M. & Ryu, S. E. Structure of human FIH-1 reveals a unique active site pocket and interaction sites for HIF-1 and von Hippel-Lindau. J. Biol. Chem. 278, 7558-7563 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 7558-7563
-
-
Lee, C.1
Kim, S.J.2
Jeong, D.G.3
Lee, S.M.4
Ryu, S.E.5
-
28
-
-
33646505724
-
Structural insights into histone demethylation by JMJD2 family members
-
Chen, Z. et al. Structural insights into histone demethylation by JMJD2 family members. Cell 125, 691-702 (2006). A report of the first crystal structure of the enzymatic domain of an active JmjC-domain-containing histone demethylase, JHDM3A/JMJD2A.
-
(2006)
Cell
, vol.125
, pp. 691-702
-
-
Chen, Z.1
-
29
-
-
33645891676
-
Structural studies on 2-oxoglutarate oxygenases and related double-stranded β-helix fold proteins
-
Clifton, I. J. et al. Structural studies on 2-oxoglutarate oxygenases and related double-stranded β-helix fold proteins. J. Inorg. Biochem. 100, 644-669 (2006).
-
(2006)
J. Inorg. Biochem.
, vol.100
, pp. 644-669
-
-
Clifton, I.J.1
-
30
-
-
0042121237
-
Multiple sequence alignment with the Clustal series of programs
-
Chenna, R. et al. Multiple sequence alignment with the Clustal series of programs. Nucleic Acids Res. 31, 3497-3500 (2003).
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 3497-3500
-
-
Chenna, R.1
-
31
-
-
0034849408
-
MrBayes: Bayesian inference of phylogenetic trees
-
Huelsenbeck, J. P. & Ronquist, F. MrBayes: Bayesian inference of phylogenetic trees. Bioinformatics 17, 754-755 (2001).
-
(2001)
Bioinformatics
, vol.17
, pp. 754-755
-
-
Huelsenbeck, J.P.1
Ronquist, F.2
-
32
-
-
0041386108
-
MrBayes 3: Bayesian phylogenetic inference under mixed models
-
Ronquist, F. & Huelsenbeck, J. P. MrBayes 3: Bayesian phylogenetic inference under mixed models. Bioinformatics 19, 1572-1574 (2003).
-
(2003)
Bioinformatics
, vol.19
, pp. 1572-1574
-
-
Ronquist, F.1
Huelsenbeck, J.P.2
-
33
-
-
0037443054
-
Identification of genes that protect the Caenorhabditis elegans genome against mutations by genome-wide RNAi
-
Pothof, J. et al. Identification of genes that protect the Caenorhabditis elegans genome against mutations by genome-wide RNAi. Genes Dev. 17, 443-448 (2003).
-
(2003)
Genes Dev.
, vol.17
, pp. 443-448
-
-
Pothof, J.1
-
34
-
-
0038655454
-
A novel JmjC domain protein modulates heterochromatization in fission yeast
-
Ayoub, N. et al. A novel JmjC domain protein modulates heterochromatization in fission yeast. Mol. Cell. Biol. 23, 4356-4370 (2003). The authors show that Epe1 has important roles in modulating heterochromatin formation and provide a basis for speculation that the JmjC domain might have histone demethylase activity.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 4356-4370
-
-
Ayoub, N.1
-
35
-
-
0030602813
-
SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box
-
Bai, C. et al. SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box. Cell 86, 263-274 (1996).
-
(1996)
Cell
, vol.86
, pp. 263-274
-
-
Bai, C.1
-
36
-
-
8644278033
-
Binding to nonmethylated CpG DNA is essential for target recognition, transactivation, and myeloid transformation by an MLL oncoprotein
-
Ayton, P. M., Chen, E. H. & Cleary, M. L. Binding to nonmethylated CpG DNA is essential for target recognition, transactivation, and myeloid transformation by an MLL oncoprotein. Mol. Cell. Biol. 24, 10470-10478 (2004).
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 10470-10478
-
-
Ayton, P.M.1
Chen, E.H.2
Cleary, M.L.3
-
37
-
-
1842505317
-
MBD1 is recruited to both methylated and nonmethylated CpGs via distinct DNA binding domains
-
Jorgensen, H. F., Ben-Porath, I. & Bird, A. P. MBD1 is recruited to both methylated and nonmethylated CpGs via distinct DNA binding domains. Mol. Cell. Biol. 24, 3387-3395 (2004).
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 3387-3395
-
-
Jorgensen, H.F.1
Ben-Porath, I.2
Bird, A.P.3
-
38
-
-
29244438472
-
CpG-binding protein (CXXC finger protein 1) is a component of the mammalian SET1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast SET1/COMPASS complex
-
Lee, J. H. & Skalnik, D. G. CpG-binding protein (CXXC finger protein 1) is a component of the mammalian SET1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast SET1/COMPASS complex. J. Biol. Chem. 280, 41725-41731 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 41725-41731
-
-
Lee, J.H.1
Skalnik, D.G.2
-
39
-
-
33744552663
-
Swi6/HP1 recruits a JmjC-domain protein to facilitate transcription of heterochromatic repeats
-
Zofall, M. & Grewal, S. I. Swi6/HP1 recruits a JmjC-domain protein to facilitate transcription of heterochromatic repeats. Mol. Cell 22, 681-692 (2006). The authors demonstrate that Epe1 functions in heterochromatin to promote Pol II accessibility by counteracting repressive chromatin.
-
(2006)
Mol. Cell
, vol.22
, pp. 681-692
-
-
Zofall, M.1
Grewal, S.I.2
-
40
-
-
0032788052
-
PHF2, a novel PHD finger gene located on human chromosome 9q22. Mamm
-
Hasenpusch-Theil, K. et al. PHF2, a novel PHD finger gene located on human chromosome 9q22. Mamm. Genome 10, 294-298 (1999).
-
(1999)
Genome
, vol.10
, pp. 294-298
-
-
Hasenpusch-Theil, K.1
-
41
-
-
26944461197
-
Mutations in PHF8 are associated with X linked mental retardation and cleft lip/cleft palate
-
Laumonnier, F. et al. Mutations in PHF8 are associated with X linked mental retardation and cleft lip/cleft palate. J. Med. Genet. 42, 780-786 (2005).
-
(2005)
J. Med. Genet.
, vol.42
, pp. 780-786
-
-
Laumonnier, F.1
-
42
-
-
0033066271
-
X linked mental retardation associated with cleft lip/palate maps to Xp11.3-q21.3
-
Siderius, L. E. et al. X linked mental retardation associated with cleft lip/palate maps to Xp11.3-q21.3. Am. J. Med. Genet. 85, 216-220 (1999).
-
(1999)
Am. J. Med. Genet.
, vol.85
, pp. 216-220
-
-
Siderius, L.E.1
-
43
-
-
20244369068
-
New genes with roles in the Caenorhabditis elegans embryo revealed using RNAi of ovary-enriched ORFeome clones
-
Fernandez, A. G. et al. New genes with roles in the Caenorhabditis elegans embryo revealed using RNAi of ovary-enriched ORFeome clones. Genome Res. 15, 250-259 (2005).
-
(2005)
Genome Res.
, vol.15
, pp. 250-259
-
-
Fernandez, A.G.1
-
44
-
-
0035464960
-
Monogenic causes of X linked mental retardation
-
Chelly, J. & Mandel, J. L. Monogenic causes of X linked mental retardation. Nature Rev. Genet. 2, 669-680 (2001).
-
(2001)
Nature Rev. Genet.
, vol.2
, pp. 669-680
-
-
Chelly, J.1
Mandel, J.L.2
-
45
-
-
0025808021
-
Cloning of cDNAs for cellular proteins that bind to the retinoblastoma gene product
-
Defeo-Jones, D. et al. Cloning of cDNAs for cellular proteins that bind to the retinoblastoma gene product. Nature 352, 251-254 (1991).
-
(1991)
Nature
, vol.352
, pp. 251-254
-
-
Defeo-Jones, D.1
-
46
-
-
0028293649
-
Partial inactivation of the RB product in a family with incomplete penetrance of familial retinoblastoma and benign retinal tumors
-
Kratzke, R. A. et al. Partial inactivation of the RB product in a family with incomplete penetrance of familial retinoblastoma and benign retinal tumors. Oncogene 9, 1321-1326 (1994).
-
(1994)
Oncogene
, vol.9
, pp. 1321-1326
-
-
Kratzke, R.A.1
-
47
-
-
20444429760
-
Binding of pRB to the PHD protein RBP2 promotes cellular differentiation
-
Benevolenskaya, E. V., Murray, H. L., Branton, P., Young, R. A. & Kaelin, W. G. Jr. Binding of pRB to the PHD protein RBP2 promotes cellular differentiation. Mol. Cell 18, 623-635 (2005).
-
(2005)
Mol. Cell
, vol.18
, pp. 623-635
-
-
Benevolenskaya, E.V.1
Murray, H.L.2
Branton, P.3
Young, R.A.4
Kaelin Jr., W.G.5
-
48
-
-
0035958918
-
Retinoblastoma-binding protein 2 (Rbp2) potentiates nuclear hormone receptor-mediated transcription
-
Chan, S. W. & Hong, W. Retinoblastoma-binding protein 2 (Rbp2) potentiates nuclear hormone receptor-mediated transcription. J. Biol. Chem. 276, 28402-28412 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 28402-28412
-
-
Chan, S.W.1
Hong, W.2
-
49
-
-
0038748632
-
A novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically upregulated in breast cancer
-
Lu, P. J. et al. A novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically upregulated in breast cancer. J. Biol. Chem. 274, 15633-15645 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 15633-15645
-
-
Lu, P.J.1
-
50
-
-
0242468568
-
PLU-1, a transcriptional repressor and putative testis-cancer antigen, has a specific expression and localisation pattern during meiosis
-
Madsen, B. et al. PLU-1, a transcriptional repressor and putative testis-cancer antigen, has a specific expression and localisation pattern during meiosis. Chromosoma 112, 124-132 (2003).
-
(2003)
Chromosoma
, vol.112
, pp. 124-132
-
-
Madsen, B.1
-
51
-
-
10644226726
-
Characterisation and developmental expression of mouse Plu-1, a homologue of a human nuclear protein (PLU-1) which is specifically upregulated in breast cancer
-
Madsen, B. et al. Characterisation and developmental expression of mouse Plu-1, a homologue of a human nuclear protein (PLU-1) which is specifically upregulated in breast cancer. Mech. Dev. 119, S239-S246 (2002).
-
(2002)
Mech. Dev.
, vol.119
-
-
Madsen, B.1
-
52
-
-
0038757840
-
Human PLU-1 Has transcriptional repression properties and interacts with the developmental transcription factors BF-1 and PAX9
-
Tan, K. et al. Human PLU-1 Has transcriptional repression properties and interacts with the developmental transcription factors BF-1 and PAX9. J. Biol. Chem. 278, 20507-20513 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 20507-20513
-
-
Tan, K.1
-
53
-
-
0029092140
-
Human H-Y: A male-specific histocompatibility antigen derived from the SMCY protein
-
Wang, W. et al. Human H-Y: a male-specific histocompatibility antigen derived from the SMCY protein. Science 269, 1588-1590 (1995).
-
(1995)
Science
, vol.269
, pp. 1588-1590
-
-
Wang, W.1
-
54
-
-
0029096075
-
Identification of a mouse male-specific transplantation antigen, H-Y
-
Scott, D. M. et al. Identification of a mouse male-specific transplantation antigen, H-Y. Nature 376, 695-698 (1995).
-
(1995)
Nature
, vol.376
, pp. 695-698
-
-
Scott, D.M.1
-
55
-
-
0033786540
-
A screen for new trithorax group genes identified little imaginal discs, the Drosophila melanogaster homologue of human retinoblastoma binding protein 2
-
Gildea, J. J., Lopez, R. & Shearn, A. A screen for new trithorax group genes identified little imaginal discs, the Drosophila melanogaster homologue of human retinoblastoma binding protein 2. Genetics 156, 645-663 (2000).
-
(2000)
Genetics
, vol.156
, pp. 645-663
-
-
Gildea, J.J.1
Lopez, R.2
Shearn, A.3
-
56
-
-
11244302905
-
Roles of JUMONJI in mouse embryonic development
-
Jung, J., Mysliwiec, M. R. & Lee, Y. Roles of JUMONJI in mouse embryonic development. Dev. Dyn. 232, 21-32 (2005).
-
(2005)
Dev. Dyn.
, vol.232
, pp. 21-32
-
-
Jung, J.1
Mysliwiec, M.R.2
Lee, Y.3
-
57
-
-
0032772975
-
Jumonji gene is essential for the neurulation and cardiac development of mouse embryos with a C3H/He background
-
Takeuchi, T., Kojima, M., Nakajima, K. & Kondo, S. Jumonji gene is essential for the neurulation and cardiac development of mouse embryos with a C3H/He background. Mech. Dev. 86, 29-38 (1999).
-
(1999)
Mech. Dev.
, vol.86
, pp. 29-38
-
-
Takeuchi, T.1
Kojima, M.2
Nakajima, K.3
Kondo, S.4
-
58
-
-
24744466509
-
Jumonji regulates cardiomyocyte proliferation via interaction with retinoblastoma protein
-
Jung, J., Kim, T. G., Lyons, G. E., Kim, H. R. & Lee, Y. Jumonji regulates cardiomyocyte proliferation via interaction with retinoblastoma protein. J. Biol. Chem. 280, 30916-30923 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 30916-30923
-
-
Jung, J.1
Kim, T.G.2
Lyons, G.E.3
Kim, H.R.4
Lee, Y.5
-
59
-
-
8644286257
-
Jumonji represses atrial natriuretic factor gene expression by inhibiting transcriptional activities of cardiac transcription factors
-
Kim, T. G., Chen, J., Sadoshima, J. & Lee, Y. Jumonji represses atrial natriuretic factor gene expression by inhibiting transcriptional activities of cardiac transcription factors. Mol. Cell. Biol. 24, 10151-10160 (2004).
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 10151-10160
-
-
Kim, T.G.1
Chen, J.2
Sadoshima, J.3
Lee, Y.4
-
60
-
-
14644396193
-
Jumonji represses alpha-cardiac myosin heavy chain expression via inhibiting MEF2 activity
-
Kim, T. G., Jung, J., Mysliwiec, M. R., Kang, S. & Lee, Y. Jumonji represses alpha-cardiac myosin heavy chain expression via inhibiting MEF2 activity. Biochem. Biophys. Res. Commun. 329, 544-553 (2005).
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.329
, pp. 544-553
-
-
Kim, T.G.1
Jung, J.2
Mysliwiec, M.R.3
Kang, S.4
Lee, Y.5
-
61
-
-
8844265508
-
Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins
-
Ringrose, L. & Paro, R. Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins. Annu. Rev. Genet. 38, 413-443 (2004).
-
(2004)
Annu. Rev. Genet.
, vol.38
, pp. 413-443
-
-
Ringrose, L.1
Paro, R.2
-
62
-
-
16544389546
-
Identification and characterization of JMJD2 family genes in silico
-
Katoh, M. & Katoh, M. Identification and characterization of JMJD2 family genes in silico. Int. J. Oncol. 24, 1623-1628 (2004).
-
(2004)
Int. J. Oncol.
, vol.24
, pp. 1623-1628
-
-
Katoh, M.1
Katoh, M.2
-
63
-
-
0034282790
-
Identification of a novel gene, GASC1, within an amplicon at 9p23-24 frequently detected in esophageal cancer cell lines
-
Yang, Z. Q. et al. Identification of a novel gene, GASC1, within an amplicon at 9p23-24 frequently detected in esophageal cancer cell lines. Cancer Res. 60, 4735-4739 (2000).
-
(2000)
Cancer Res.
, vol.60
, pp. 4735-4739
-
-
Yang, Z.Q.1
-
64
-
-
22544465244
-
JMJD2A is a novel N-CoR-interacting protein and is involved in repression of the human transcription factor achaete scute-like homologue 2 (ASCL2/Hash2)
-
Zhang, D., Yoon, H. G. & Wong, J. JMJD2A is a novel N-CoR-interacting protein and is involved in repression of the human transcription factor achaete scute-like homologue 2 (ASCL2/Hash2). Mol. Cell. Biol. 25, 6404-6414 (2005).
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 6404-6414
-
-
Zhang, D.1
Yoon, H.G.2
Wong, J.3
-
65
-
-
23344436787
-
Functional characterization of JMJD2A, a histone deacetylase- And retinoblastoma-binding protein
-
Gray, S. G. et al. Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein. J. Biol. Chem. 280, 28507-28518 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 28507-28518
-
-
Gray, S.G.1
-
66
-
-
33645502395
-
Tudor, MBT and chromo domains gauge the degree of lysine methylation
-
Kim, J. et al. Tudor, MBT and chromo domains gauge the degree of lysine methylation. EMBO Rep. 7, 397-403 (2006).
-
(2006)
EMBO Rep.
, vol.7
, pp. 397-403
-
-
Kim, J.1
-
67
-
-
33646438365
-
Recognition of hstone H3 lysine-4 methylation by the double tudor domain of JMJD2A
-
Huang, Y., Fang, J., Bedford, M. T., Zhang, Y. & Xu, R. M. Recognition of hstone H3 lysine-4 methylation by the double tudor domain of JMJD2A. Science 312, 748-751 (2006).
-
(2006)
Science
, vol.312
, pp. 748-751
-
-
Huang, Y.1
Fang, J.2
Bedford, M.T.3
Zhang, Y.4
Xu, R.M.5
-
68
-
-
20444380510
-
Spatial distribution of di- and trimethyl lysine 36 of histone H3 at active genes
-
Bannister, A. J. et al. Spatial distribution of di- and trimethyl lysine 36 of histone H3 at active genes. J. Biol. Chem. 280, 17732-17736 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 17732-17736
-
-
Bannister, A.J.1
-
69
-
-
0345286865
-
RPH1 and GIS1 are damage-responsive repressors of PHR1
-
Jang, Y. K., Wang, L. & Sancar, G. B. RPH1 and GIS1 are damage-responsive repressors of PHR1. Mol. Cell. Biol. 19, 7630-7638 (1999).
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 7630-7638
-
-
Jang, Y.K.1
Wang, L.2
Sancar, G.B.3
-
70
-
-
0029658730
-
An H-YDb epitope is encoded by a novel mouse Y chromosome gene
-
Greenfield, A. et al. An H-YDb epitope is encoded by a novel mouse Y chromosome gene. Nature Genet. 14, 474-478 (1996).
-
(1996)
Nature Genet.
, vol.14
, pp. 474-478
-
-
Greenfield, A.1
-
71
-
-
6844242334
-
The UTX gene escapes X inactivation in mice and humans
-
Greenfield, A. et al. The UTX gene escapes X inactivation in mice and humans. Hum. Mol. Genet. 7, 737-742 (1998).
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 737-742
-
-
Greenfield, A.1
-
72
-
-
0035909531
-
A novel nuclear protein, 5qNCA (LOC51780) is a candidate for the myeloid leukemia tumor suppressor gene on chromosome 5 band q31
-
Hu, Z. et al. A novel nuclear protein, 5qNCA (LOC51780) is a candidate for the myeloid leukemia tumor suppressor gene on chromosome 5 band q31. Oncogene 20, 6946-6954 (2001).
-
(2001)
Oncogene
, vol.20
, pp. 6946-6954
-
-
Hu, Z.1
-
73
-
-
0028031305
-
Structure and expression of the hairless gene of mice
-
Cachon-Gonzalez, M. B. et al. Structure and expression of the hairless gene of mice. Proc. Natl Acad. Sci. USA 91, 7717-7721 (1994).
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 7717-7721
-
-
Cachon-Gonzalez, M.B.1
-
74
-
-
6844265562
-
Alopecia universalis associated with a mutation in the human hairless gene
-
Ahmad, W. et al. Alopecia universalis associated with a mutation in the human hairless gene. Science 279, 720-724 (1998).
-
(1998)
Science
, vol.279
, pp. 720-724
-
-
Ahmad, W.1
-
75
-
-
0035887252
-
The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor
-
Potter, G. B. et al. The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor. Genes Dev. 15, 2687-2701 (2001).
-
(2001)
Genes Dev.
, vol.15
, pp. 2687-2701
-
-
Potter, G.B.1
-
76
-
-
0025790483
-
Analysis of a murine male germ cell-specific transcript that encodes a putative zinc finger protein
-
Hoog, C., Schalling, M., Grunder-Brundell, E. & Daneholt, B. Analysis of a murine male germ cell-specific transcript that encodes a putative zinc finger protein. Mol. Reprod. Dev. 30, 173-181 (1991).
-
(1991)
Mol. Reprod. Dev.
, vol.30
, pp. 173-181
-
-
Hoog, C.1
Schalling, M.2
Grunder-Brundell, E.3
Daneholt, B.4
-
77
-
-
0028876893
-
Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor
-
Lee, J. W., Choi, H. S., Gyuris, J., Brent, R. & Moore, D. D. Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor. Mol. Endocrinol. 9, 243-254 (1995).
-
(1995)
Mol. Endocrinol.
, vol.9
, pp. 243-254
-
-
Lee, J.W.1
Choi, H.S.2
Gyuris, J.3
Brent, R.4
Moore, D.D.5
-
78
-
-
0037386143
-
Intracellular localisation of human HIF-1α hydroxylases: Implications for oxygen sensing
-
Metzen, E. et al. Intracellular localisation of human HIF-1α hydroxylases: implications for oxygen sensing. J. Cell Sci. 116, 1319-1326 (2003).
-
(2003)
J. Cell Sci.
, vol.116
, pp. 1319-1326
-
-
Metzen, E.1
-
79
-
-
0037144437
-
A novel myc target gene, mina53, that is involved in cell proliferation
-
Tsuneoka, M., Koda, Y., Soejima, M., Teye, K. & Kimura, H. A novel myc target gene, mina53, that is involved in cell proliferation. J. Biol. Chem. 277, 35450-35459 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 35450-35459
-
-
Tsuneoka, M.1
Koda, Y.2
Soejima, M.3
Teye, K.4
Kimura, H.5
-
80
-
-
23744490410
-
The human mineral dust-induced gene, MDIG, is a cell growth regulating gene associated with lung cancer
-
Zhang, Y. et al. The human mineral dust-induced gene, MDIG, is a cell growth regulating gene associated with lung cancer. Oncogene 24, 4873-4882 (2005).
-
(2005)
Oncogene
, vol.24
, pp. 4873-4882
-
-
Zhang, Y.1
-
81
-
-
14844350834
-
Protein NO52 - A constitutive nucleolar component sharing high sequence homologies to protein NO66
-
Eilbracht, J., Kneissel, S., Hofmann, A. & Schmidt-Zachmann, M. S. Protein NO52 - a constitutive nucleolar component sharing high sequence homologies to protein NO66. Eur. J. Cell Biol. 84, 279-294 (2005).
-
(2005)
Eur. J. Cell Biol.
, vol.84
, pp. 279-294
-
-
Eilbracht, J.1
Kneissel, S.2
Hofmann, A.3
Schmidt-Zachmann, M.S.4
-
82
-
-
1642464624
-
NO66, a highly conserved dual location protein in the nucleolus and in a special type of synchronously replicating chromatin
-
Eilbracht, J. et al. NO66, a highly conserved dual location protein in the nucleolus and in a special type of synchronously replicating chromatin. Mol. Biol. Cell 15, 1816-1832 (2004).
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 1816-1832
-
-
Eilbracht, J.1
-
83
-
-
0033605747
-
Molecular cloning of two new human paralogs of 85 kDa cytosolic phospholipase A2
-
Pickard, R. T., Strifler, B. A., Kramer, R. M. & Sharp, J. D. Molecular cloning of two new human paralogs of 85 kDa cytosolic phospholipase A2. J. Biol. Chem. 274, 8823-8831 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8823-8831
-
-
Pickard, R.T.1
Strifler, B.A.2
Kramer, R.M.3
Sharp, J.D.4
-
84
-
-
16644382118
-
Regulatory mechanism and physiological role of cytosolic phospholipase A2
-
Hirabayashi, T., Murayama, T. & Shimizu, T. Regulatory mechanism and physiological role of cytosolic phospholipase A2. Biol. Pharm. Bull. 27, 1168-1173 (2004).
-
(2004)
Biol. Pharm. Bull.
, vol.27
, pp. 1168-1173
-
-
Hirabayashi, T.1
Murayama, T.2
Shimizu, T.3
-
85
-
-
0034705508
-
Identification and characterization of a novel protein from Sertoli cells, PASS1, that associates with mammalian small stress protein hsp27
-
Liu, C., Gilmont, R. R., Benndorf, R. & Welsh, M. J. Identification and characterization of a novel protein from Sertoli cells, PASS1, that associates with mammalian small stress protein hsp27. J. Biol. Chem. 275, 18724-18731 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 18724-18731
-
-
Liu, C.1
Gilmont, R.R.2
Benndorf, R.3
Welsh, M.J.4
-
86
-
-
0042334606
-
Disruption of a novel gene, DIRC3, and expression of DIRC3-HSPBAP1 fusion transcripts in a case of familial renal cell cancer and t(2;3)(q35;q21)
-
Bodmer, D., Schepens, M., Eleveld, M. J., Schoenmakers, E. F. & Geurts van Kessel, A. Disruption of a novel gene, DIRC3, and expression of DIRC3-HSPBAP1 fusion transcripts in a case of familial renal cell cancer and t(2;3)(q35;q21). Genes Chromosomes Cancer 38, 107-116 (2003).
-
(2003)
Genes Chromosomes Cancer
, vol.38
, pp. 107-116
-
-
Bodmer, D.1
Schepens, M.2
Eleveld, M.J.3
Schoenmakers, E.F.4
Van Geurts Kessel, A.5
-
87
-
-
0034604029
-
A receptor for phosphatidylserine-specific clearance of apoptotic cells
-
Fadok, V. A. et al. A receptor for phosphatidylserine-specific clearance of apoptotic cells. Nature 405, 85-90 (2000).
-
(2000)
Nature
, vol.405
, pp. 85-90
-
-
Fadok, V.A.1
-
88
-
-
1942489369
-
Defective fetal liver erythropoiesis and T lymphopoiesis in mice lacking the phosphatidylserine receptor
-
Kunisaki, Y. et al. Defective fetal liver erythropoiesis and T lymphopoiesis in mice lacking the phosphatidylserine receptor. Blood 103, 3362-3364 (2004).
-
(2004)
Blood
, vol.103
, pp. 3362-3364
-
-
Kunisaki, Y.1
-
89
-
-
23044433837
-
The phosphatidylserine receptor has essential functions during embryogenesis but not in apoptotic cell removal
-
Bose, J. et al. The phosphatidylserine receptor has essential functions during embryogenesis but not in apoptotic cell removal. J. Biol. 3, 15 (2004).
-
(2004)
J. Biol.
, vol.3
, pp. 15
-
-
Bose, J.1
-
90
-
-
0346690073
-
Nuclear localization of the phosphatidylserine receptor protein via multiple nuclear localization signals
-
Cui, P., Qin, B., Liu, N., Pan, G. & Pei, D. Nuclear localization of the phosphatidylserine receptor protein via multiple nuclear localization signals. Exp. Cell Res. 293, 154-163 (2004).
-
(2004)
Exp. Cell Res.
, vol.293
, pp. 154-163
-
-
Cui, P.1
Qin, B.2
Liu, N.3
Pan, G.4
Pei, D.5
-
91
-
-
10144255178
-
The phosphatidylserine receptor from Hydra is a nuclear protein with potential Fe(II) dependent oxygenase activity
-
Cikala, M. et al. The phosphatidylserine receptor from Hydra is a nuclear protein with potential Fe(II) dependent oxygenase activity. BMC Cell Biol. 5, 26 (2004).
-
(2004)
BMC Cell Biol.
, vol.5
, pp. 26
-
-
Cikala, M.1
-
92
-
-
0034632829
-
Regulation of chromatin structure by site-specific histone H3 methyltransferases
-
Rea, S. et al. Regulation of chromatin structure by site-specific histone H3 methyltransferases. Nature 406, 593-599 (2000).
-
(2000)
Nature
, vol.406
, pp. 593-599
-
-
Rea, S.1
-
93
-
-
2642542643
-
A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin
-
Schotta, G. et al. A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin. Genes Dev. 18, 1251-1262 (2004).
-
(2004)
Genes Dev.
, vol.18
, pp. 1251-1262
-
-
Schotta, G.1
-
94
-
-
27444436367
-
Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase
-
Sun, X. J. et al. Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase. J. Biol. Chem. 280, 35261-35271 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 35261-35271
-
-
Sun, X.J.1
-
95
-
-
0034977239
-
The polycomb-group gene Ezh2 is required for early mouse development
-
O'Carroll, D. et al. The polycomb-group gene Ezh2 is required for early mouse development. Mol. Cell. Biol. 21, 4330-4336 (2001).
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 4330-4336
-
-
O'Carroll, D.1
-
96
-
-
33646882068
-
Polycomb complexes repress developmental regulators in murine embryonic stem cells
-
Boyer, L. A. et al. Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature 441, 349-353 (2006).
-
(2006)
Nature
, vol.441
, pp. 349-353
-
-
Boyer, L.A.1
-
97
-
-
33644877451
-
SMART 5: Domains in the context of genomes and networks
-
Letunic, I. et al. SMART 5: domains in the context of genomes and networks. Nucleic Acids Res. 34, D257-D260 (2006).
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Letunic, I.1
-
98
-
-
0032568655
-
SMART, a simple modular architecture research tool: Identification of signaling domains
-
Schultz, J., Milpetz, F., Bork, P. & Ponting, C. P. SMART, a simple modular architecture research tool: identification of signaling domains. Proc. Natl Acad. Sci. USA 95, 5857-5864 (1998).
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 5857-5864
-
-
Schultz, J.1
Milpetz, F.2
Bork, P.3
Ponting, C.P.4
-
99
-
-
9144257886
-
The Pfam protein families database
-
Bateman, A. et al. The Pfam protein families database. Nucleic Acids Res. 32, D138-D141 (2004).
-
(2004)
Nucleic Acids Res.
, vol.32
-
-
Bateman, A.1
-
100
-
-
0024297354
-
Multiple sequence alignment with hierarchical clustering
-
Corpet, F. Multiple sequence alignment with hierarchical clustering. Nucleic Acids Res. 16, 10881-10890 (1988).
-
(1988)
Nucleic Acids Res.
, vol.16
, pp. 10881-10890
-
-
Corpet, F.1
-
101
-
-
3242810318
-
MEGA3: Integrated software for molecular evolutionary genetics analysis and sequence alignment
-
Kumar, S., Tamura, K. & Nei, M. MEGA3: integrated software for molecular evolutionary genetics analysis and sequence alignment. Brief Bioinform. 5, 150-163 (2004).
-
(2004)
Brief Bioinform.
, vol.5
, pp. 150-163
-
-
Kumar, S.1
Tamura, K.2
Nei, M.3
|