Asparaginase treatment side-effects may be due to genes with homopolymeric Asn codons (Review-Hypothesis)

International Journal of Molecular Medicine

Volumn 36, Issue 3, 2015, Pages 607-625

  Banerji, Julian ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Asparaginase; Cystic fibrosis; Diabetes; Immune response; Insulin regulatory substrate 2; Leukemia; Lipodystrophy; Lymphoma; Pancreatitis; Salmonella

Indexed keywords

AMINOACYL TRANSFER RNA; AROMATASE; ASPARAGINASE; ASPARAGINE; BLOOD CLOTTING FACTOR 5; BRCA2 PROTEIN; COMPLEMENT FACTOR; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; CYTOCHROME P450 1A1; DNA METHYLTRANSFERASE 3A; FANCONI ANEMIA PROTEIN; FIBRINOGEN; G PROTEIN COUPLED RECEPTOR; GUANOSINE TRIPHOSPHATASE; INITIATION FACTOR 2ALPHA; INSULIN RECEPTOR SUBSTRATE 2; INTERLEUKIN 23 RECEPTOR; INTERLEUKIN 8 RECEPTOR; INTRINSICALLY DISORDERED PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; NOTCH RECEPTOR; POLYGLUTAMINE; POTASSIUM CHANNEL KV1.3; PREDNISOLONE; PROTEIN MDM2; SONIC HEDGEHOG PROTEIN; THIOREDOXIN INTERACTING PROTEIN; TRANSFER RNA; UNINDEXED DRUG; WNT PROTEIN; ANTINEOPLASTIC AGENT; CODON; PEPTIDE; POLYASPARAGINE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ATAXIA; CODON; CYSTIC FIBROSIS; DIABETES MELLITUS; DRUG POTENTIATION; DYSLIPIDEMIA; GENE EXPRESSION; GENE TRANSLOCATION; GENETIC ASSOCIATION; HOMEOSTASIS; HOMOPOLYMERIC CODING REGION; HUMAN; HYPERGLYCEMIA; INFLAMMATION; LIPODYSTROPHY; LYMPHOMA; MENTAL DISEASE; MICROBIOME; MULTIGENE FAMILY; NEUROLOGIC DISEASE; NONHUMAN; PANCREATITIS; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEIN STRUCTURE; REVIEW; RNA TRANSLATION; SALMONELLA; SIDE EFFECT; VASCULAR DISEASE; ANIMAL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROTEIN SYNTHESIS; RIBOSOME;

ANIMALS; ANTINEOPLASTIC AGENTS; ASPARAGINASE; ASPARAGINE; CODON; GENE EXPRESSION REGULATION; HUMANS; PEPTIDES; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROTEIN BIOSYNTHESIS; RIBOSOMES;

EID: 84938064152     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2015.2285     Document Type: Review

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