A short splice form of Xin-actin binding repeat containing 2 (XIRP2) lacking the xin repeats is required for maintenance of stereocilia morphology and hearing function

Journal of Neuroscience

Volumn 35, Issue 5, 2015, Pages 1999-2014

  Francis, Shimon P ^a   Krey, Jocelyn F ^c   Krystofiak, Evan S ^d   Cui, Runjia ^d   Nanda, Sonali ^a   Xu, Wenhao ^a   Kachar, Bechara ^d   Barr Gillespie, Peter G ^c   Shin, Jung Bum ^a,b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

CRISPR; Hair bundle; Hair cell; Hearing; Stereocilia; XIRP2

Indexed keywords

ACTIN; CRISPR ASSOCIATED PROTEIN; CRISPR ASSOCIATED PROTEIN 9; UNCLASSIFIED DRUG; XIN ACTIN BINDING REPEAT CONTAINING 2; DNA BINDING PROTEIN; ISOPROTEIN; LIM PROTEIN; NUCLEAR PROTEIN; XIRP2 PROTEIN, MOUSE;

ADULT; ANIMAL TISSUE; ARTICLE; CELL DEGENERATION; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; DATA ANALYSIS; FEMALE; GENE MUTATION; GENETIC ANALYSIS; GENETIC TRANSFECTION; HAIR FOLLICLE; HEARING; HIGH FREQUENCY HEARING LOSS; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MASS SPECTROMETRY; MOUSE; MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY; SPATIOTEMPORAL ANALYSIS; STEREOCILIUM; TRANSMISSION ELECTRON MICROSCOPY; UTRICLE; ANIMAL; C57BL MOUSE; CBA MOUSE; CELL CULTURE; CHICK EMBRYO; GENETICS; HAIR CELL; HEARING IMPAIRMENT; METABOLISM; PHYSIOLOGY; PROTEIN TRANSPORT; RAT; ULTRASTRUCTURE;

ANIMALS; CELLS, CULTURED; CHICK EMBRYO; DNA-BINDING PROTEINS; HAIR CELLS, AUDITORY; HEARING; HEARING LOSS; LIM DOMAIN PROTEINS; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; NUCLEAR PROTEINS; PROTEIN ISOFORMS; PROTEIN TRANSPORT; RATS; STEREOCILIA;

EID: 84922355311     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3449-14.2015     Document Type: Article

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