Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism

Journal of Biological Chemistry

Volumn 273, Issue 23, 1998, Pages 14484-14494

  Hara, Kenta ^a,b   Yonezawa, Kazuyoshi ^b   Weng, Qing Ping ^a   Kozlowski, Mark T ^a   Belham, Christopher ^a   Avruch, Joseph ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b KOBE UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; INITIATION FACTOR 4E; INSULIN; INSULIN RECEPTOR KINASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE; RAPAMYCIN;

ANIMAL CELL; ARTICLE; CHO CELL; DEPHOSPHORYLATION; ENZYME INACTIVATION; HUMAN; HUMAN CELL; KIDNEY CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACIDS; ANDROSTADIENES; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CARRIER PROTEINS; CELL LINE; CRICETINAE; CULTURE MEDIA; HUMANS; INSULIN; PHOSPHOPROTEINS; PHOSPHORYLATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PHOSPHOTYROSINE; POLYENES; PROTEIN BIOSYNTHESIS; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RIBOSOMAL PROTEIN S6 KINASES; SEQUENCE DELETION; SIGNAL TRANSDUCTION; SIROLIMUS;

ANIMALIA; MAMMALIA;

EID: 0032486268     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.23.14484     Document Type: Article

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