Association of six genetic variants with myocardial infarction

International Journal of Molecular Medicine

Volumn 35, Issue 5, 2015, Pages 1451-1459

  Matsuoka, Reiko ^a   Abe, Shintaro ^a   Tokoro, Fumitaka ^a   Arai, Masazumi ^a   Noda, Toshiyuki ^a   Watanabe, Sachiro ^a   Horibe, Hideki ^b   Fujimaki, Tetsuo ^c   Oguri, Mitsutoshi ^d   Kato, Kimihiko ^e   Minatoguchi, Shinya ^f   Yamada, Yoshiji ^g  

^a GIFU PREFECTURAL GIFU HOSPITAL   (Japan)

^b GIFU PREFECTURAL TAJIMI HOSPITAL   (Japan)

^c Inabe General Hospital   (Japan)

^d JAPANESE RED CROSS NAGOYA FIRST HOSPITAL   (Japan)

^e Meitoh Hospital   (Japan)

^f GIFU UNIVERSITY   (Japan)

^g MIE UNIVERSITY   (Japan)

Author keywords

Acute coronary syndrome; Coronary artery disease; Genetics; Myocardial infarction; Polymorphism

Indexed keywords

ADULT; ARTICLE; CAUCASIAN; CDKN2B GENE; CNNM2 GENE; CONTROLLED STUDY; FEMALE; FLT1 GENE; GENE; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HEART INFARCTION; HUMAN; ISCHEMIC HEART DISEASE; JAPANESE (PEOPLE); LPL GENE; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; PHACTR1 GENE; PRIORITY JOURNAL; PSRC1 GENE; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; AGED; ALLELE; ASIAN CONTINENTAL ANCESTRY GROUP; CASE CONTROL STUDY; CLINICAL TRIAL; GENETIC PREDISPOSITION; GENETICS; JAPAN; MULTICENTER STUDY; MYOCARDIAL INFARCTION;

AGED; ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; JAPAN; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 84925387581     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2015.2115     Document Type: Article

References (33)

1. Yusuf S, Hawken S, Ounpuu S, et al: Effect of potentially modifable risk factors associated with myocardial infarction In 52 countries (the INTERHEART study): case-control study. Lancet 364:937-952, 2004.
2. Topol EJ, Smith J, Plow EF and Wang QK: Genetic susceptibility to myocardial infarction and coronary artery disease. Hum Mol Genet 15:R117-R123, 2006.
3. Wang Q: Molecular genetics of coronary artery disease. Curr Opin Cardiol 20:182-188, 2005
4. Peden JF and Farrall M: Thirty-five common variants for coronary artery disease: the fruits of much collaborative labour. Hum Mol Genet 20:R198-R205, 2011.
5. CARDIoGRAMplusC4D Consortium: Large-scale association analysis identifes new risk loci for coronary artery disease. Nat Genet 45:25-33, 2013.
6. Schunkert H, König IR, Kathiresan S, et al: Large-scale association analysis identifes 13 new susceptibility loci for coronary artery disease. Nat Genet 43:333-338, 2011.
7. Itoh Y, Mizuki N, Shimada T, et al: High-throughput DNA typing of HLA-A, -B, -C, and-DRB1 loci by a PCR-SSOP-Luminex method in the Japanese population. Immunogenetics 57717-729, 2005
8. Peli W, Nairn AC and Page R: Structural basis for protein phosphatase 1 regulation and specificity. FEBS J 280:596-611, 2013.
9. Jarray R, Allain B, Borriello L, et al: Depletion of the novel protein PHACTR-1 from human endothelial cells abolishes tube formation and induces cell death receptor apoptosis. Biochimie 93:1668-1675, 2011.
10. Mount PF, Kemp BE and Power DA: Regulation of endothelial and myocardial NO synthesis by multi-site eNOS phosphorylation. J Mol Cell Cardiol 42:271-279, 2007
11. Patel RS, Morris AA, Ahmed Y, et al: A genetic risk variant for myocardial infarction on chromosome 6p24 is associated with impaired central hemodynamic indexes. Am J Hypertens 25:797-803, 2012.
12. Helgadottir A, Thorleifsson G, Manolescu A, et al: A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science 316:1491-1493, 2007
13. McPherson R, Pertsemlidis A, Kavaslar N, et al: A common allele on chromosome 9 associated with coronary heart disease. Science 316:1488-1491, 2007
14. Samani NJ, Erdmann J, Hall AS, et al: Genomewide association analysis of coronary artery disease. N Engl J Med 357443-453, 2007
15. Wellcome Trust Case Control Consortium: Genome-wide association study of 14, 000 cases of seven common diseases and 3, 000 shared controls. Nature 447661-678, 2007
16. Matarin M, Brown WM, Singleton A, Hardy JA and Meschia JF; ISGS investigators: Whole genome analyses suggest ischemic stroke and heart disease share an association with polymorphisms on chromosome 9p21. Stroke 39:1586-1589, 2008.
17. Gschwendtner A, Bevan S, Cole JW, et al: Sequence variants on chromosome 9p21.3 confer risk for atherosclerotic stroke. Ann Neurol 65:531-539, 2009.
18. Helgadottir A, Thorleifsson G, Magnusson K P, et al: The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm. Nat Genet 40:217-224, 2008.
19. Musunuru K, Post WS, Herzog W, et al: Association of single nucleotide polymorphisms on chromosome 9p21.3 with platelet reactivity: a potential mechanism for increased vascular disease. Circ Cardiovasc Genet 3:445-453, 2010.
20. Jarinova O, Stewart AF, Roberts R, et al: Functional analysis of the chromosome 9p21.3 coronary artery disease risk locus. Arterioscler Thromb Vasc Biol 29:1671-1677, 2009.
21. Harismendy O, Notani D, Song X, et al:9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response. Nature 470:264-268, 2011.
22. Visel A, Zhu Y, May D, et al: Targeted deletion of the 9p21 noncoding coronary artery disease risk interval in mice. Nature 464:409-412, 2010.
23. Fisher RM, Humphries SE and Talmud PJ: Common variation in the lipoprotein lipase gene: effect on plasma lipids and risk of atherosclerosis. Atherosclerosis 135:145-159, 1997.
24. Eriksson JW, Buren J, Svensson M, Olivecrona T and Olivecrona G: Postprandial regulation of blood lipids and adipose tissue lipoprotein lipase in type 2 diabetes patients and healthy control subjects. Atherosclerosis 166:359-367, 2003.
25. Jansen P, Giehl K, Nyengaard JR, et al: Roles for the proneurotrophin receptor sortilin in neuronal development, aging and brain injury. Nat Neurosci 10:1449-1457, 2007.
26. Nielsen MS, Jacobsen C, Olivecrona G, Gliemann J and Petersen CM: Sortilin/neurotensin receptor-3 binds and mediates degradation of lipoprotein lipase. J Biol Chem 274:8832-8836, 1999.
27. Nilsson SK, Christensen S, Raarup MK, Ryan RO, Nielsen MS and Olivecrona G: Endocytosis of apolipoprotein A-V by members of the low density lipoprotein receptor and the VPS10p domain receptor families. J Biol Chem 283:25920-25927, 2008.
28. Stuiver M, Lainez S, Will C, et al: CNNM2, encoding a basolateral protein required for renal Mg2+ handling, is mutated in dominant hypomagnesemia. Am J Hum Genet 88:333-343, 2011.
29. De Baaij JHF, Stuiver M, Meij IC, et al: Membrane topology and intracellular processing of cyclin M2 (CNNM2). J Biol Chem 287:13644-13655, 2012.
30. Khurana R, Moons L, Shaf S, et al: Placental growth factor promotes atherosclerotic intimal thickening and macrophage accumulation. Circulation 111:2828-2836, 2005.
31. Pilarczyk K, Sattler KJ, Galili O, et al: Placenta growth factor expression in human atherosclerotic carotid plaques is related to plaque destabilization. Atherosclerosis 196:333-340, 2008.
32. Roncal C, Buysschaert I, Gerdes N, et al: Short-term delivery of anti-PlGF antibody delays progression of atherosclerotic plaques to vulnerable lesions. Cardiovasc Res 86:29-36, 2010.
33. Carmeliet P, Moons L, Luttun A, et al: Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions. Nat Med 7:575-583, 2001.