Genomic responses in mouse models poorly mimic human inflammatory diseases

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 9, 2013, Pages 3507-3512

  Junhee Seok, ^a   H Shaw Warren, ^b   Alex G Cuenca, ^c   Michael N Mindrinos, ^a   Henry V Baker, ^c   Xu, Weihong ^a   Richards, Daniel R ^d   McDonald Smith, Grace P ^b   Gao, Hong ^a   Hennessy, Laura ^e   Finnerty, Celeste C ^f   López, Cecilia M ^c   Honari, Shari ^e   Moore, Ernest E ^g   Minei, Joseph P ^h   Cuschieri, Joseph ^e   Bankey, Paul E ⁱ   Johnson, Jeffrey L ^g   Sperry, Jason ^j   Nathens, Avery B ^k   Billiar, Timothy R ^j   West, Michael A ^l   Jeschke, Marc G ^m   Klein, Matthew B ^e   Gamelli, Richard L ⁿ   Gibran, Nicole S ^e   Brownstein, Bernard H ^o   Miller Graziano, Carol ⁱ   Calvano, Steve E ^p   Mason, Philip H ^b   Cobb, J Perren ^b   Rahme, Laurence G ^b   Lowry, Stephen F ^p   Maier, Ronald V ^e   Moldawer, Lyle L ^c   Herndon, David N ^f   Davis, Ronald W ^a   Xiao, Wenzhong ^a,b   Tompkins, Ronald G ^b   more..

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^d MAIngenuity Systems Inc   (United States)

^e UNIVERSITY OF WASHINGTON   (United States)

^f University of Texas Medical Branch School of Medicine   (United States)

^g UNIVERSITY OF COLORADO   (United States)

^h UNIVERSITY OF TEXAS AT DALLAS   (United States)

ⁱ UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^j PRESBYTERIAN UNIVERSITY HOSPITAL   (United States)

^k ST MICHAEL'S HOSPITAL   (Canada)

^l UNIVERSITY OF CALIFORNIA   (United States)

^m UNIVERSITY OF TORONTO   (Canada)

ⁿ LOYOLA UNIVERSITY CHICAGO   (United States)

^o WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^p ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

more..

Author keywords

Human disease; Immune response; Inflammation; Injury; Translational medicine

Indexed keywords

ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BURN; CONTROLLED STUDY; ENDOTOXEMIA; EXPERIMENTAL MODEL; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENOME; HUMAN; HUMAN VERSUS ANIMAL COMPARISON; INFECTION; INFLAMMATORY DISEASE; INJURY; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEPSIS; SIGNAL TRANSDUCTION; TRANSLATIONAL RESEARCH;

ACUTE DISEASE; ADOLESCENT; ADULT; ANIMALS; BURNS; DISEASE MODELS, ANIMAL; ENDOTOXEMIA; FEMALE; GENE EXPRESSION REGULATION; GENOMICS; HUMANS; INFLAMMATION; MALE; MICE; MICE, INBRED C57BL; SIGNAL TRANSDUCTION; TIME FACTORS; WOUNDS AND INJURIES; YOUNG ADULT;

EID: 84874457770     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1222878110     Document Type: Article

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