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Volumn 22, Issue 8, 2012, Pages 1717-1727

IRS-2 deficiency impairs NMDA receptor-dependent long-term potentiation

Author keywords

diabetes; insulin receptor signaling; long term potentiation; NMDA receptor; synaptic plasticity

Indexed keywords

INSULIN RECEPTOR SUBSTRATE 2; MITOGEN ACTIVATED PROTEIN KINASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; POSTSYNAPTIC DENSITY PROTEIN 95; POSTSYNAPTIC RECEPTOR; PROTEIN KINASE B; PROTEIN KINASE FYN;

EID: 84863700380     PISSN: 10473211     EISSN: 14602199     Source Type: Journal    
DOI: 10.1093/cercor/bhr216     Document Type: Article
Times cited : (67)

References (83)
  • 1
    • 0028032895 scopus 로고
    • Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene
    • DOI 10.1038/372186a0
    • Araki E, Lipes MA, Patti ME, Bruning JC, Haag B, Johnson RS, Kahn CR. 1994. Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene. Nature. 372:186-190. (Pubitemid 24347839)
    • (1994) Nature , vol.372 , Issue.6502 , pp. 186-190
    • Araki, E.1    Lipes, M.A.2    Patti, M.-E.3    Bruning, J.C.4    Haag III, B.5    Johnson, R.S.6    Kahn, C.R.7
  • 2
    • 23044482894 scopus 로고    scopus 로고
    • Diabetes mellitus concomitantly facilitates the induction of long-term depression and inhibits that of long-term potentiation in hippocampus
    • DOI 10.1111/j.1460-9568.2005.04205.x
    • Artola A, Kamal A, Ramakers GM, Biessels GJ, Gispen WH. 2005. Diabetes mellitus concomitantly facilitates the induction of longterm depression and inhibits that of long-term potentiation in hippocampus. Eur J Neurosci. 22:169-178. (Pubitemid 41059982)
    • (2005) European Journal of Neuroscience , vol.22 , Issue.1 , pp. 169-178
    • Artola, A.1    Kamal, A.2    Ramakers, G.M.J.3    Biessels, G.J.4    Gispen, W.H.5
  • 3
    • 0031919552 scopus 로고    scopus 로고
    • Insulin signal transduction through protein kinase cascades
    • DOI 10.1023/A:1006823109415
    • Avruch J. 1998. Insulin signal transduction through protein kinase cascades. Mol Cell Biochem. 182:31-48. (Pubitemid 28181646)
    • (1998) Molecular and Cellular Biochemistry , vol.182 , Issue.1-2 , pp. 31-48
    • Avruch, J.1
  • 4
    • 0027361094 scopus 로고
    • Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain
    • Baura GD, Foster DM, Porte D, Jr., Kahn SE, Bergman RN, Cobelli C, Schwartz MW. 1993. Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain. J Clin Invest. 92:1824-1830. (Pubitemid 23304549)
    • (1993) Journal of Clinical Investigation , vol.92 , Issue.4 , pp. 1824-1830
    • Baura, G.D.1    Foster, D.M.2    Porte Jr., D.3    Kahn, S.E.4    Bergman, R.N.5    Cobelli, C.6    Schwartz, M.W.7
  • 7
    • 0027476024 scopus 로고
    • A synaptic model of memory: Long-term potentiation in the hippocampus
    • DOI 10.1038/361031a0
    • Bliss TV, Collingridge GL. 1993. A synaptic model of memory: long-term potentiation in the hippocampus. Nature. 361:31-39. (Pubitemid 23020772)
    • (1993) Nature , vol.361 , Issue.6407 , pp. 31-39
    • Bliss, T.V.P.1    Collingridge, G.L.2
  • 9
    • 44649198605 scopus 로고    scopus 로고
    • Insulin Receptor Signaling Regulates Synapse Number, Dendritic Plasticity, and Circuit Function In Vivo
    • DOI 10.1016/j.neuron.2008.04.014, PII S0896627308003668
    • Chiu SL, Chen CM, Cline HT. 2008. Insulin receptor signaling regulates synapse number, dendritic plasticity, and circuit function in vivo. Neuron. 58:708-719. (Pubitemid 351778469)
    • (2008) Neuron , vol.58 , Issue.5 , pp. 708-719
    • Chiu, S.-L.1    Chen, C.-M.2    Cline, H.T.3
  • 11
    • 0022516633 scopus 로고
    • Insulin is released from rat brain neuronal cells in culture
    • Clarke DW, Mudd L, Boyd FT, Jr., Fields M, Raizada MK. 1986. Insulin is released from rat brain neuronal cells in culture. J Neurochem. 47:831-836. (Pubitemid 16029565)
    • (1986) Journal of Neurochemistry , vol.47 , Issue.3 , pp. 831-836
    • Clarke, D.W.1    Mudd, L.2    Boyd Jr., F.T.3
  • 12
    • 0020647470 scopus 로고
    • Excitatory amino acids in synaptic transmission in the Schaffer collateral-commissural pathway of the rat hippocampus
    • Collingridge GL, Kehl SJ, McLennan H. 1983. Excitatory amino acids in synaptic transmission in the Schaffer collateral-commissural pathway of the rat hippocampus. J Physiol. 334:33-46. (Pubitemid 13176081)
    • (1983) Journal of Physiology , vol.334 , pp. 33-46
    • Collingridge, G.L.1    Kehl, S.J.2    McLennan, H.3
  • 13
    • 34147173277 scopus 로고    scopus 로고
    • Insulin resistance and Alzheimer's disease pathogenesis: Potential mechanisms and implications for treatment
    • DOI 10.2174/156720507780362137
    • Craft S. 2007. Insulin resistance and Alzheimer's disease pathogenesis: potential mechanisms and implications for treatment. Curr Alzheimer Res. 4:147-152. (Pubitemid 46557503)
    • (2007) Current Alzheimer Research , vol.4 , Issue.2 , pp. 147-152
    • Craft, S.1
  • 14
    • 0028308407 scopus 로고
    • Unique catalytic properties dictate the enhanced function of p59fynT, the hemopoietic cellspecific isoform of the Fyn tyrosine protein kinase, in T cells
    • Davidson D, Viallet J, Veillette A. 1994. Unique catalytic properties dictate the enhanced function of p59fynT, the hemopoietic cellspecific isoform of the Fyn tyrosine protein kinase, in T cells. Mol Cell Biol. 14:4554-4564.
    • (1994) Mol Cell Biol , vol.14 , pp. 4554-4564
    • Davidson, D.1    Viallet, J.2    Veillette, A.3
  • 15
    • 1842507154 scopus 로고    scopus 로고
    • Neurocognitive Correlates of Type 1 Diabetes Mellitus in Childhood
    • DOI 10.1076/chin.10.1.36.26241
    • Desrocher M, Rovet J. 2004. Neurocognitive correlates of type 1 diabetes mellitus in childhood. Child Neuropsychol. 10:36-52. (Pubitemid 38418932)
    • (2004) Child Neuropsychology , vol.10 , Issue.1 , pp. 36-52
    • Desrocher, M.1    Rovet, J.2
  • 16
    • 28844495644 scopus 로고    scopus 로고
    • Insulin receptor signaling in long-term memory consolidation following spatial learning
    • DOI 10.1101/lm.88005
    • Dou JT, Chen M, Dufour F, Alkon DL, Zhao WQ. 2005. Insulin receptor signaling in long-term memory consolidation following spatial learning. Learn Mem. 12:646-655. (Pubitemid 41770090)
    • (2005) Learning and Memory , vol.12 , Issue.6 , pp. 646-655
    • Dou, J.-T.1    Chen, M.2    Dufour, F.3    Alkon, D.L.4    Zhao, W.-Q.5
  • 17
    • 0037327636 scopus 로고    scopus 로고
    • Lower cognitive function in the presence of obesity and hypertension: The Framingham heart study
    • DOI 10.1038/sj.ijo.802225
    • Elias MF, Elias PK, Sullivan LM, Wolf PA, D'Agostino RB. 2003. Lower cognitive function in the presence of obesity and hypertension: the Framingham heart study. Int J Obes Relat Metab Disord. 27: 260-268. (Pubitemid 36255810)
    • (2003) International Journal of Obesity , vol.27 , Issue.2 , pp. 260-268
    • Elias, M.F.1    Elias, P.K.2    Sullivan, L.M.3    Wolf, P.A.4    D'Agostino, R.B.5
  • 18
    • 0345579566 scopus 로고    scopus 로고
    • Activation of p42 mitogen-activated protein kinase in hippocampal long term potentiation
    • DOI 10.1074/jbc.271.40.24329
    • English JD, Sweatt JD. 1996. Activation of p42 mitogen-activated protein kinase in hippocampal long term potentiation. J Biol Chem. 271:24329-24332. (Pubitemid 26333160)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.40 , pp. 24329-24332
    • English, J.D.1    David Sweatt, J.2
  • 19
    • 58549092371 scopus 로고    scopus 로고
    • Organization and dynamics of PDZ-domainrelated supramodules in the postsynaptic density
    • Feng W, Zhang M. 2009. Organization and dynamics of PDZ-domainrelated supramodules in the postsynaptic density. Nat Rev Neurosci. 10:87-99.
    • (2009) Nat Rev Neurosci , vol.10 , pp. 87-99
    • Feng, W.1    Zhang, M.2
  • 20
    • 0028029856 scopus 로고
    • Insulin receptor substrate-1 (IRS-1) distribution in the rat central nervous system
    • Folli F, Bonfanti L, Renard E, Kahn CR, Merighi A. 1994. Insulin receptor substrate-1 (IRS-1) distribution in the rat central nervous system. J Neurosci. 14:6412-6422. (Pubitemid 24333063)
    • (1994) Journal of Neuroscience , vol.14 , Issue.11 , pp. 6412-6422
    • Folli, F.1    Bonfanti, L.2    Renard, E.3    Kahn, C.R.4    Merighi, A.5
  • 21
    • 0026700490 scopus 로고
    • Expression of insulin-like growth factor i by astrocytes in response to injury
    • Garcia-Estrada J, Garcia-Segura LM, Torres-Aleman I. 1992. Expression of insulin-like growth factor I by astrocytes in response to injury. Brain Res. 592:343-347.
    • (1992) Brain Res , vol.592 , pp. 343-347
    • Garcia-Estrada, J.1    Garcia-Segura, L.M.2    Torres-Aleman, I.3
  • 22
    • 0026010614 scopus 로고
    • Localization of insulin-like growth factor i (IGF-I)-like immunoreactivity in the developing and adult rat brain
    • Garcia-Segura LM, Perez J, Pons S, Rejas MT, Torres-Aleman I. 1991. Localization of insulin-like growth factor I (IGF-I)-like immunoreactivity in the developing and adult rat brain. Brain Res. 560:167-174.
    • (1991) Brain Res , vol.560 , pp. 167-174
    • Garcia-Segura, L.M.1    Perez, J.2    Pons, S.3    Rejas, M.T.4    Torres-Aleman, I.5
  • 23
    • 0027092647 scopus 로고
    • Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice
    • Grant SG, O'Dell TJ, Karl KA, Stein PL, Soriano P, Kandel ER. 1992. Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice. Science. 258:1903-1910. (Pubitemid 23026728)
    • (1992) Science , vol.258 , Issue.5090 , pp. 1903-1910
    • Grant, S.G.N.1    O'Dell, T.J.2    Karl, K.A.3    Stein, P.L.4    Soriano, P.5    Kandel, E.R.6
  • 25
    • 0025361209 scopus 로고
    • Analysis of excitatory synaptic action in pyramidal cells using whole-cell recording from rat hippocampal slices
    • Hestrin S, Nicoll RA, Perkel DJ, Sah P. 1990. Analysis of excitatory synaptic action in pyramidal cells using whole-cell recording from rat hippocampal slices. J Physiol. 422:203-225. (Pubitemid 20109856)
    • (1990) Journal of Physiology , vol.422 , pp. 203-225
    • Hestrin, S.1    Nicoll, R.A.2    Perkel, D.J.3    Sah, P.4
  • 26
    • 0036285710 scopus 로고    scopus 로고
    • DNA damage and the effect of antioxidants in streptozotocin-treated mice
    • DOI 10.1016/S0278-6915(02)00014-5, PII S0278691502000145
    • Imaeda A, Kaneko T, Aoki T, Kondo Y, Nagase H. 2002. DNA damage and the effect of antioxidants in streptozotocin-treated mice. Food Chem Toxicol. 40:979-987. (Pubitemid 34626706)
    • (2002) Food and Chemical Toxicology , vol.40 , Issue.7 , pp. 979-987
    • Imaeda, A.1    Kaneko, T.2    Aoki, T.3    Kondo, Y.4    Nagase, H.5
  • 27
    • 33644941776 scopus 로고    scopus 로고
    • Synaptic transmission changes in the pyramidal cells of the hippocampus in streptozotocin-induced diabetes mellitus in rats
    • Kamal A, Biessels GJ, Gispen WH, Ramakers GM. 2006. Synaptic transmission changes in the pyramidal cells of the hippocampus in streptozotocin-induced diabetes mellitus in rats. Brain Res. 1073-1074:276-280.
    • (2006) Brain Res , vol.1073-1074 , pp. 276-280
    • Kamal, A.1    Biessels, G.J.2    Gispen, W.H.3    Ramakers, G.M.4
  • 31
    • 0028242805 scopus 로고
    • Amplitude fluctuations of dual-component EPSCs in hippocampal pyramidal cells: Implications for long-term potentiation
    • DOI 10.1016/0896-6273(94)90318-2
    • Kullmann DM. 1994. Amplitude fluctuations of dual-component EPSCs in hippocampal pyramidal cells: implications for long-term potentiation. Neuron. 12:1111-1120. (Pubitemid 24178202)
    • (1994) Neuron , vol.12 , Issue.5 , pp. 1111-1120
    • Kullmann, D.M.1
  • 34
    • 0029000105 scopus 로고
    • Insulin potentiates N-methyl-D-aspartate receptor activity in Xenopus oocytes and rat hippocampus
    • Liu L, Brown JC, 3rd, Webster WW, Morrisett RA, Monaghan DT. 1995. Insulin potentiates N-methyl-D-aspartate receptor activity in Xenopus oocytes and rat hippocampus. Neurosci Lett. 192:5-8.
    • (1995) Neurosci Lett , vol.192 , pp. 5-8
    • Liu, L.1    Brown Iii., J.C.2    Webster, W.W.3    Morrisett, R.A.4    Monaghan, D.T.5
  • 35
    • 0033581023 scopus 로고    scopus 로고
    • Insulin receptor substrate 3 is not essential for growth or glucose homeostasis
    • Liu SC, Wang Q, Lienhard GE, Keller SR. 1999. Insulin receptor substrate 3 is not essential for growth or glucose homeostasis. J Biol Chem. 274:18093-18099.
    • (1999) J Biol Chem , vol.274 , pp. 18093-18099
    • Liu, S.C.1    Wang, Q.2    Lienhard, G.E.3    Keller, S.R.4
  • 36
    • 5344256250 scopus 로고    scopus 로고
    • Hyperinsulinemia and risk of Alzheimer disease
    • Luchsinger JA, Tang MX, Shea S, Mayeux R. 2004. Hyperinsulinemia and risk of Alzheimer disease. Neurology. 63:1187-1192. (Pubitemid 39350015)
    • (2004) Neurology , vol.63 , Issue.7 , pp. 1187-1192
    • Luchsinger, J.A.1    Tang, M.-X.2    Shea, S.3    Mayeux, R.4
  • 37
    • 0033578855 scopus 로고    scopus 로고
    • Long-term potentiation-a decade of progress?
    • Malenka RC, Nicoll RA. 1999. Long-term potentiation-a decade of progress? Science. 285:1870-1874.
    • (1999) Science , vol.285 , pp. 1870-1874
    • Malenka, R.C.1    Nicoll, R.A.2
  • 39
    • 18344415030 scopus 로고    scopus 로고
    • Caffeine-mediated presynaptic long-term potentiation in hippocampal CA1 pyramidal neurons
    • DOI 10.1152/jn.00601.2002
    • Martin ED, Buno W. 2003. Caffeine-mediated presynaptic long-term potentiation in hippocampal CA1 pyramidal neurons. J Neurophysiol. 89:3029-3038. (Pubitemid 36682655)
    • (2003) Journal of Neurophysiology , vol.89 , Issue.6 , pp. 3029-3038
    • Martin, E.D.1    Buno, W.2
  • 40
    • 1242351257 scopus 로고    scopus 로고
    • Valproate reduced excitatory postsynaptic currents in hippocampal CA1 pyramidal neurons
    • DOI 10.1016/j.neuropharm.2003.10.013
    • Martin ED, Pozo MA. 2004. Valproate reduced excitatory postsynaptic currents in hippocampal CA1 pyramidal neurons. Neuropharmacology. 46:555-561. (Pubitemid 38224441)
    • (2004) Neuropharmacology , vol.46 , Issue.4 , pp. 555-561
    • Martin, E.D.1    Pozo, M.A.2
  • 41
    • 0030744872 scopus 로고    scopus 로고
    • Insulin-stimulated tyrosine phosphorylation of caveolin is specific for the differentiated adipocyte phenotype in 3T3-L1 cells
    • DOI 10.1074/jbc.272.33.20706
    • Mastick CC, Saltiel AR. 1997. Insulin-stimulated tyrosine phosphorylation of caveolin is specific for the differentiated adipocyte phenotype in 3T3-L1 cells. J Biol Chem. 272:20706-20714. (Pubitemid 27355635)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.33 , pp. 20706-20714
    • Mastick, C.C.1    Saltiel, A.R.2
  • 42
    • 28444433338 scopus 로고    scopus 로고
    • Impact of impaired glucose tolerance and type 2 diabetes on cognitive aging
    • Messier C. 2005. Impact of impaired glucose tolerance and type 2 diabetes on cognitive aging. Neurobiol Aging. 26(Suppl 1):26-30.
    • (2005) Neurobiol Aging , vol.26 , Issue.SUPPL. 1 , pp. 26-30
    • Messier, C.1
  • 43
    • 71349085957 scopus 로고    scopus 로고
    • Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling
    • Moloney AM, Griffin RJ, Timmons S, O'Connor R, Ravid R, O'Neill C. 2010. Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling. Neurobiol Aging. 31:224-243.
    • (2010) Neurobiol Aging , vol.31 , pp. 224-243
    • Moloney, A.M.1    Griffin, R.J.2    Timmons, S.3    O'Connor, R.4    Ravid, R.5    O'Neill, C.6
  • 45
    • 0033047334 scopus 로고    scopus 로고
    • Expression mechanisms underlying NMDA receptor-dependent long-term potentiation
    • DOI 10.1111/j.1749-6632.1999.tb11320.x
    • Nicoll RA, Malenka RC. 1999. Expression mechanisms underlying NMDA receptor-dependent long-term potentiation. Ann N Y Acad Sci. 868:515-525. (Pubitemid 29281159)
    • (1999) Annals of the New York Academy of Sciences , vol.868 , pp. 515-525
    • Nicoll, R.A.1    Malenka, R.C.2
  • 48
    • 0034810063 scopus 로고    scopus 로고
    • Postsynaptic conversion of silent synapses during LTP affects synaptic gain and transmission dynamics
    • DOI 10.1038/nn719
    • Poncer JC, Malinow R. 2001. Postsynaptic conversion of silent synapses during LTP affects synaptic gain and transmission dynamics. Nat Neurosci. 4:989-996. (Pubitemid 32924138)
    • (2001) Nature Neuroscience , vol.4 , Issue.10 , pp. 989-996
    • Poncer, J.C.1    Malinow, R.2
  • 49
    • 0026040183 scopus 로고
    • Ontogeny of insulin-like growth factor I, its receptor, and its binding proteins in the rat hypothalamus
    • Pons S, Rejas MT, Torres-Aleman I. 1991. Ontogeny of insulin-like growth factor I, its receptor, and its binding proteins in the rat hypothalamus. Brain Res Dev Brain Res. 62:169-175.
    • (1991) Brain Res Dev Brain Res , vol.62 , pp. 169-175
    • Pons, S.1    Rejas, M.T.2    Torres-Aleman, I.3
  • 52
    • 0031889760 scopus 로고    scopus 로고
    • Doxorubicin, streptozocin, and 5-fluorouracil chemotherapy for patients with metastatic islet-cell carcinoma
    • DOI 10.1097/00000421-199802000-00008
    • Rivera E, Ajani JA. 1998. Doxorubicin, streptozocin, and 5-fluorouracil chemotherapy for patients with metastatic islet-cell carcinoma. Am J Clin Oncol. 21:36-38. (Pubitemid 28092969)
    • (1998) American Journal of Clinical Oncology: Cancer Clinical Trials , vol.21 , Issue.1 , pp. 36-38
    • Rivera, E.1    Ajani, J.A.2
  • 53
    • 33644591150 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: Link to brain reductions in acetylcholine
    • Rivera EJ, Goldin A, Fulmer N, Tavares R, Wands JR, de la Monte SM. 2005. Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: link to brain reductions in acetylcholine. J Alzheimers Dis. 8:247-268.
    • (2005) J Alzheimers Dis , vol.8 , pp. 247-268
    • Rivera, E.J.1    Goldin, A.2    Fulmer, N.3    Tavares, R.4    Wands, J.R.5    De La Monte, S.M.6
  • 55
    • 0029833009 scopus 로고    scopus 로고
    • Enhanced tyrosine phosphorylation of the 2B subunit of the Nmethyl-D-aspartate receptor in long-term potentiation
    • Rostas JA, Brent VA, Voss K, Errington ML, Bliss TV, Gurd JW. 1996. Enhanced tyrosine phosphorylation of the 2B subunit of the Nmethyl-D-aspartate receptor in long-term potentiation. Proc Natl Acad Sci USA. 93:10452-10456.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 10452-10456
    • Rostas, J.A.1    Brent, V.A.2    Voss, K.3    Errington, M.L.4    Bliss, T.V.5    Gurd, J.W.6
  • 56
    • 0037456565 scopus 로고    scopus 로고
    • Drugs of abuse and stress trigger a common synaptic adaptation in dopamine neurons
    • DOI 10.1016/S0896-6273(03)00021-7
    • Saal D, Dong Y, Bonci A, Malenka RC. 2003. Drugs of abuse and stress trigger a common synaptic adaptation in dopamine neurons. Neuron. 37:577-582. (Pubitemid 36262980)
    • (2003) Neuron , vol.37 , Issue.4 , pp. 577-582
    • Saal, D.1    Dong, Y.2    Bonci, A.3    Malenka, R.C.4
  • 60
    • 33646848241 scopus 로고    scopus 로고
    • Kinase Suppressor of Ras1 Compartmentalizes Hippocampal Signal Transduction and Subserves Synaptic Plasticity and Memory Formation
    • DOI 10.1016/j.neuron.2006.04.029, PII S0896627306003394
    • Shalin SC, Hernandez CM, Dougherty MK, Morrison DK, Sweatt JD. 2006. Kinase suppressor of Ras1 compartmentalizes hippocampal signal transduction and subserves synaptic plasticity and memory formation. Neuron. 50:765-779. (Pubitemid 43775734)
    • (2006) Neuron , vol.50 , Issue.5 , pp. 765-779
    • Shalin, S.C.1    Hernandez, C.M.2    Dougherty, M.K.3    Morrison, D.K.4    Sweatt, J.D.5
  • 61
    • 0035030492 scopus 로고    scopus 로고
    • The postsynaptic NMDA-receptor-PSD-95 signaling complex in excitatory synapses of the brain
    • Sheng M. 2001. The postsynaptic NMDA-receptor-PSD-95 signaling complex in excitatory synapses of the brain. J Cell Sci. 114:1251. (Pubitemid 32409461)
    • (2001) Journal of Cell Science , vol.114 , Issue.7 , pp. 1251
    • Sheng, M.1
  • 63
    • 39749137437 scopus 로고    scopus 로고
    • Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons
    • DOI 10.1038/nn2055, PII NN2055
    • Stranahan AM, Arumugam TV, Cutler RG, Lee K, Egan JM, Mattson MP. 2008. Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons. Nat Neurosci. 11:309-317. (Pubitemid 351311802)
    • (2008) Nature Neuroscience , vol.11 , Issue.3 , pp. 309-317
    • Stranahan, A.M.1    Arumugam, T.V.2    Cutler, R.G.3    Lee, K.4    Egan, J.M.5    Mattson, M.P.6
  • 64
    • 15844409347 scopus 로고    scopus 로고
    • The Fyn tyrosine kinase binds Irs-1 and forms a distinct signaling complex during insulin stimulation
    • DOI 10.1074/jbc.271.18.10583
    • Sun XJ, Pons S, Asano T, Myers MG, Jr., Glasheen E, White MF. 1996. The Fyn tyrosine kinase binds Irs-1 and forms a distinct signaling complex during insulin stimulation. J Biol Chem. 271:10583-10587. (Pubitemid 26149894)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.18 , pp. 10583-10587
    • Sun, X.J.1    Pons, S.2    Asano, T.3    Myers Jr., M.G.4    Glasheen, E.5    White, M.F.6
  • 66
    • 0024345665 scopus 로고
    • Distribution of insulin receptor-like immunoreactivity in the rat forebrain
    • DOI 10.1016/0306-4522(89)90036-5
    • Unger J, McNeill TH, Moxley RT, 3rd, White M, Moss A, Livingston JN. 1989. Distribution of insulin receptor-like immunoreactivity in the rat forebrain. Neuroscience. 31:143-157. (Pubitemid 19209704)
    • (1989) Neuroscience , vol.31 , Issue.1 , pp. 143-157
    • Unger, J.1    McNeill, T.H.2    Moxley III, R.T.3    White, M.4    Moss, A.5    Livingston, J.N.6
  • 67
    • 23844470857 scopus 로고    scopus 로고
    • Insulin modulates hippocampal activity-dependent synaptic plasticity in a N-methyl-D-aspartate receptor and phosphatidyl-inositol-3-kinase-dependent manner
    • DOI 10.1111/j.1471-4159.2005.03269.x
    • Van der Heide LP, Kamal A, Artola A, Gispen WH, Ramakers GM. 2005. Insulin modulates hippocampal activity-dependent synaptic plasticity in a N-methyl-d-aspartate receptor and phosphatidyl-inositol-3-kinase-dependent manner. J Neurochem. 94:1158-1166. (Pubitemid 41170602)
    • (2005) Journal of Neurochemistry , vol.94 , Issue.4 , pp. 1158-1166
    • Van Der Heide, L.P.1    Kamal, A.2    Artola, A.3    Gispen, W.H.4    Ramakers, G.M.J.5
  • 69
    • 33846020076 scopus 로고    scopus 로고
    • A receptors
    • DOI 10.1016/j.neuropharm.2006.06.023, PII S0028390806002000
    • Vetiska SM, Ahmadian G, Ju W, Liu L, Wymann MP, Wang YT. 2007. GABAA receptor-associated phosphoinositide 3-kinase is required for insulin-induced recruitment of postsynaptic GABAA receptors. Neuropharmacology. 52:146-155. (Pubitemid 46039779)
    • (2007) Neuropharmacology , vol.52 , Issue.1 , pp. 146-155
    • Vetiska, S.M.1    Ahmadian, G.2    Ju, W.3    Liu, L.4    Wymann, M.P.5    Wang, Y.T.6
  • 70
    • 33749531024 scopus 로고    scopus 로고
    • Rapid isolation of synaptoneurosomes and postsynaptic densities from adult mouse hippocampus
    • DOI 10.1016/j.jneumeth.2006.05.008, PII S016502700600238X
    • Villasana LE, Klann E, Tejada-Simon MV. 2006. Rapid isolation of synaptoneurosomes and postsynaptic densities from adult mouse hippocampus. J Neurosci Methods. 158:30-36. (Pubitemid 44528760)
    • (2006) Journal of Neuroscience Methods , vol.158 , Issue.1 , pp. 30-36
    • Villasana, L.E.1    Klann, E.2    Tejada-Simon, M.V.3
  • 72
    • 0037523369 scopus 로고    scopus 로고
    • Control of synaptic strength, a novel function of Akt
    • DOI 10.1016/S0896-6273(03)00356-8
    • Wang Q, Liu L, Pei L, Ju W, Ahmadian G, Lu J, Wang Y, Liu F, Wang YT. 2003. Control of synaptic strength, a novel function of Akt. Neuron. 38:915-928. (Pubitemid 36782383)
    • (2003) Neuron , vol.38 , Issue.6 , pp. 915-928
    • Wang, Q.1    Liu, L.2    Pei, L.3    Ju, W.4    Ahmadian, G.5    Lu, J.6    Wang, Y.7    Liu, F.8    Wang, Y.T.9
  • 73
    • 0030748457 scopus 로고    scopus 로고
    • The insulin signalling system and the IRS proteins
    • DOI 10.1007/s001250051387
    • White MF. 1997. The insulin signalling system and the IRS proteins. Diabetologia. 40(Suppl 2):S2-S17. (Pubitemid 27306917)
    • (1997) Diabetologia , vol.40 , Issue.SUPPL. 2
    • White, M.F.1
  • 74
    • 20544462061 scopus 로고    scopus 로고
    • Obesity in middle age and future risk of dementia: A 27 year longitudinal population based study
    • Whitmer RA, Gunderson EP, Barrett-Connor E, Quesenberry CP, Jr., Yaffe K. 2005. Obesity in middle age and future risk of dementia: a 27 year longitudinal population based study. BMJ. 330:1360.
    • (2005) BMJ , vol.330 , pp. 1360
    • Whitmer, R.A.1    Gunderson, E.P.2    Barrett-Connor, E.3    Quesenberry Jr., C.P.4    Yaffe, K.5
  • 75
    • 0033230165 scopus 로고    scopus 로고
    • ERK plays a regulatory role in induction of LTP by theta frequency stimulation and its modulation by beta-adrenergic receptors
    • Winder DG, Martin KC, Muzzio IA, Rohrer D, Chruscinski A, Kobilka B, Kandel ER. 1999. ERK plays a regulatory role in induction of LTP by theta frequency stimulation and its modulation by beta-adrenergic receptors. Neuron. 24:715-726.
    • (1999) Neuron , vol.24 , pp. 715-726
    • Winder, D.G.1    Martin, K.C.2    Muzzio, I.A.3    Rohrer, D.4    Chruscinski, A.5    Kobilka, B.6    Kandel, E.R.7
  • 76
    • 0032841435 scopus 로고    scopus 로고
    • Irs-2 coordinates Igf-1 receptor-mediated β-cell development and peripheral insulin signalling
    • DOI 10.1038/12631
    • Withers DJ, Burks DJ, Towery HH, Altamuro SL, Flint CL, White MF. 1999. Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling. Nat Genet. 23:32-40. (Pubitemid 29418784)
    • (1999) Nature Genetics , vol.23 , Issue.1 , pp. 32-40
    • Withers, D.J.1    Burks, D.J.2    Towery, H.H.3    Altamuro, S.L.4    Flint, C.L.5    White, M.F.6
  • 78
    • 33750682363 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor rapidly increases NMDA receptor channel activity through Fyn-mediated phosphorylation
    • DOI 10.1016/j.brainres.2006.08.129, PII S0006899306026345
    • Xu F, Plummer MR, Len GW, Nakazawa T, Yamamoto T, Black IB, Wu K. 2006. Brain-derived neurotrophic factor rapidly increases NMDA receptor channel activity through Fyn-mediated phosphorylation. Brain Res. 1121:22-34. (Pubitemid 44708893)
    • (2006) Brain Research , vol.1121 , Issue.1 , pp. 22-34
    • Xu, F.1    Plummer, M.R.2    Len, G.-W.3    Nakazawa, T.4    Yamamoto, T.5    Black, I.B.6    Wu, K.7
  • 80
    • 0037199092 scopus 로고    scopus 로고
    • Deficient expression of insulin receptor substrate-1 (IRS-1) fails to block insulin-like growth factor-I (IGF-I) stimulation of brain growth and myelination
    • DOI 10.1016/S0165-3806(02)00355-3, PII S0165380602003553
    • Ye P, Li L, Lund PK, D'Ercole AJ. 2002. Deficient expression of insulin receptor substrate-1 (IRS-1) fails to block insulin-like growth factor-I (IGF-I) stimulation of brain growth and myelination. Brain Res Dev Brain Res. 136:111-121. (Pubitemid 34718117)
    • (2002) Developmental Brain Research , vol.136 , Issue.2 , pp. 111-121
    • Ye, P.1    Li, L.2    Lund, P.K.3    D'Ercole, A.J.4
  • 81
    • 0031053363 scopus 로고    scopus 로고
    • NMDA channel regulation by channel-associated protein tyrosine kinase Src
    • DOI 10.1126/science.275.5300.674
    • Yu XM, Askalan R, Keil GJ, Salter MW. 1997. NMDA channel regulation by channel-associated protein tyrosine kinase Src. Science. 275:674-678. (Pubitemid 27061336)
    • (1997) Science , vol.275 , Issue.5300 , pp. 674-678
    • Yu, X.-M.1    Askalan, R.2    Keil II, G.J.3    Salter, M.W.4
  • 82
    • 0033521130 scopus 로고    scopus 로고
    • Brain insulin receptors and spatial memory: Correlated changes in gene expression, tyrosine phosphorylation, and signaling molecules in the hippocampus of water maze trained rats
    • Zhao W, Chen H, Xu H, Moore E, Meiri N, Quon MJ, Alkon DL. 1999. Brain insulin receptors and spatial memory. Correlated changes in gene expression, tyrosine phosphorylation, and signaling molecules in the hippocampus of water maze trained rats. J Biol Chem. 274:34893-34902. (Pubitemid 129509536)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.49 , pp. 34893-34902
    • Zhao, W.1    Chen, H.2    Xu, H.3    Moore, E.4    Meiri, N.5    Quon, M.J.6    Alkon, D.L.7
  • 83


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