메뉴 건너뛰기




Volumn 26, Issue 2, 2015, Pages 69-74

Effects of the gut microbiota on bone mass

Author keywords

Gut microbiota; Osteoimmunology; Osteoporosis

Indexed keywords

ANTIBIOTIC AGENT; CARBOXY TERMINAL TELOPEPTIDE; CYTOKINE; GALACTOSE OLIGOSACCHARIDE; INULIN; LEUPRORELIN; PENICILLIN DERIVATIVE; PREBIOTIC AGENT; PROBIOTIC AGENT; SEROTONIN; SEX HORMONE;

EID: 84923071266     PISSN: 10432760     EISSN: 18793061     Source Type: Journal    
DOI: 10.1016/j.tem.2014.11.004     Document Type: Review
Times cited : (182)

References (56)
  • 1
    • 33744992495 scopus 로고    scopus 로고
    • Osteoporosis
    • Sambrook P., Cooper C. Osteoporosis. Lancet 2006, 367:2010-2018.
    • (2006) Lancet , vol.367 , pp. 2010-2018
    • Sambrook, P.1    Cooper, C.2
  • 2
    • 0035055418 scopus 로고    scopus 로고
    • Classification of osteoporosis based on bone mineral densities
    • Lu Y., et al. Classification of osteoporosis based on bone mineral densities. J. Bone Miner. Res. 2001, 16:901-910.
    • (2001) J. Bone Miner. Res. , vol.16 , pp. 901-910
    • Lu, Y.1
  • 4
    • 77950251400 scopus 로고    scopus 로고
    • A human gut microbial gene catalogue established by metagenomic sequencing
    • Qin J., et al. A human gut microbial gene catalogue established by metagenomic sequencing. Nature 2010, 464:59-65.
    • (2010) Nature , vol.464 , pp. 59-65
    • Qin, J.1
  • 5
    • 66549102207 scopus 로고    scopus 로고
    • Reproducible community dynamics of the gastrointestinal microbiota following antibiotic perturbation
    • Antonopoulos D.A., et al. Reproducible community dynamics of the gastrointestinal microbiota following antibiotic perturbation. Infect. Immun. 2009, 77:2367-2375.
    • (2009) Infect. Immun. , vol.77 , pp. 2367-2375
    • Antonopoulos, D.A.1
  • 6
    • 79952756960 scopus 로고    scopus 로고
    • Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation
    • Dethlefsen L., Relman D.A. Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation. Proc. Natl. Acad. Sci. U.S.A. 2011, 108(Suppl. 1):4554-4561.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 4554-4561
    • Dethlefsen, L.1    Relman, D.A.2
  • 7
    • 79959201412 scopus 로고    scopus 로고
    • Human nutrition, the gut microbiome and the immune system
    • Kau A.L., et al. Human nutrition, the gut microbiome and the immune system. Nature 2011, 474:327-336.
    • (2011) Nature , vol.474 , pp. 327-336
    • Kau, A.L.1
  • 8
    • 84861988021 scopus 로고    scopus 로고
    • Microbiota, disease, and back to health: a metastable journey
    • Published online June 6, 2012
    • Blumberg R., Powrie F. Microbiota, disease, and back to health: a metastable journey. Sci. Transl. Med. 2012, 4. Published online June 6, 2012. 10.1126/scitranslmed.3004184.
    • (2012) Sci. Transl. Med. , vol.4
    • Blumberg, R.1    Powrie, F.2
  • 9
    • 84866168894 scopus 로고    scopus 로고
    • Functional interactions between the gut microbiota and host metabolism
    • Tremaroli V., Backhed F. Functional interactions between the gut microbiota and host metabolism. Nature 2012, 489:242-249.
    • (2012) Nature , vol.489 , pp. 242-249
    • Tremaroli, V.1    Backhed, F.2
  • 10
    • 84866167497 scopus 로고    scopus 로고
    • Reciprocal interactions of the intestinal microbiota and immune system
    • Maynard C.L., et al. Reciprocal interactions of the intestinal microbiota and immune system. Nature 2012, 489:231-241.
    • (2012) Nature , vol.489 , pp. 231-241
    • Maynard, C.L.1
  • 11
    • 44649118583 scopus 로고    scopus 로고
    • Metagenomic approaches for defining the pathogenesis of inflammatory bowel diseases
    • Peterson D.A., et al. Metagenomic approaches for defining the pathogenesis of inflammatory bowel diseases. Cell Host Microbe 2008, 3:417-427.
    • (2008) Cell Host Microbe , vol.3 , pp. 417-427
    • Peterson, D.A.1
  • 12
    • 78649686679 scopus 로고    scopus 로고
    • A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes
    • Willing B.P., et al. A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes. Gastroenterology 2010, 139:1844-1854.
    • (2010) Gastroenterology , vol.139 , pp. 1844-1854
    • Willing, B.P.1
  • 13
    • 79959961092 scopus 로고    scopus 로고
    • Twin study indicates loss of interaction between microbiota and mucosa of patients with ulcerative colitis
    • Lepage P., et al. Twin study indicates loss of interaction between microbiota and mucosa of patients with ulcerative colitis. Gastroenterology 2011, 141:227-236.
    • (2011) Gastroenterology , vol.141 , pp. 227-236
    • Lepage, P.1
  • 14
    • 66249129571 scopus 로고    scopus 로고
    • Twin studies reveal specific imbalances in the mucosa-associated microbiota of patients with ileal Crohn's disease
    • Willing B., et al. Twin studies reveal specific imbalances in the mucosa-associated microbiota of patients with ileal Crohn's disease. Inflamm. Bowel Dis. 2009, 15:653-660.
    • (2009) Inflamm. Bowel Dis. , vol.15 , pp. 653-660
    • Willing, B.1
  • 15
    • 55949124035 scopus 로고    scopus 로고
    • Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
    • Sokol H., et al. Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:16731-16736.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 16731-16736
    • Sokol, H.1
  • 16
    • 84875717908 scopus 로고    scopus 로고
    • Multicenter analysis of fecal microbiota profiles in Japanese patients with Crohn's disease
    • Andoh A., et al. Multicenter analysis of fecal microbiota profiles in Japanese patients with Crohn's disease. J. Gastroenterol. 2012, 47:1298-1307.
    • (2012) J. Gastroenterol. , vol.47 , pp. 1298-1307
    • Andoh, A.1
  • 17
    • 84912102518 scopus 로고    scopus 로고
    • Intestinal microbiota in health and disease: role of bifidobacteria in gut homeostasis
    • Tojo R., et al. Intestinal microbiota in health and disease: role of bifidobacteria in gut homeostasis. World J. Gastroenterol. 2014, 20:15163-15176.
    • (2014) World J. Gastroenterol. , vol.20 , pp. 15163-15176
    • Tojo, R.1
  • 18
    • 84871241731 scopus 로고    scopus 로고
    • Bariatric surgery, bone loss, obesity and possible mechanisms
    • Brzozowska M.M., et al. Bariatric surgery, bone loss, obesity and possible mechanisms. Obes. Rev. 2013, 14:52-67.
    • (2013) Obes. Rev. , vol.14 , pp. 52-67
    • Brzozowska, M.M.1
  • 19
    • 84869073570 scopus 로고    scopus 로고
    • Longitudinal assessment of bone mineral density in children and adolescents with inflammatory bowel disease
    • Schmidt S., et al. Longitudinal assessment of bone mineral density in children and adolescents with inflammatory bowel disease. J. Pediatr. Gastroenterol. Nutr. 2012, 55:511-518.
    • (2012) J. Pediatr. Gastroenterol. Nutr. , vol.55 , pp. 511-518
    • Schmidt, S.1
  • 20
    • 42049110350 scopus 로고    scopus 로고
    • Receptor activator of nuclear factor kappaB ligand and osteoprotegerin regulation of bone remodeling in health and disease
    • Kearns A.E., et al. Receptor activator of nuclear factor kappaB ligand and osteoprotegerin regulation of bone remodeling in health and disease. Endocr. Rev. 2008, 29:155-192.
    • (2008) Endocr. Rev. , vol.29 , pp. 155-192
    • Kearns, A.E.1
  • 21
    • 45149127782 scopus 로고    scopus 로고
    • Osteoimmunology: interactions of the bone and immune system
    • Lorenzo J., et al. Osteoimmunology: interactions of the bone and immune system. Endocr. Rev. 2008, 29:403-440.
    • (2008) Endocr. Rev. , vol.29 , pp. 403-440
    • Lorenzo, J.1
  • 22
    • 0033581952 scopus 로고    scopus 로고
    • Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand
    • Kong Y.Y., et al. Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand. Nature 1999, 402:304-309.
    • (1999) Nature , vol.402 , pp. 304-309
    • Kong, Y.Y.1
  • 23
    • 75149165271 scopus 로고    scopus 로고
    • The estrogen receptor-alpha in osteoclasts mediates the protective effects of estrogens on cancellous but not cortical bone
    • Martin-Millan M., et al. The estrogen receptor-alpha in osteoclasts mediates the protective effects of estrogens on cancellous but not cortical bone. Mol. Endocrinol. 2010, 24:323-334.
    • (2010) Mol. Endocrinol. , vol.24 , pp. 323-334
    • Martin-Millan, M.1
  • 24
    • 34548274444 scopus 로고    scopus 로고
    • Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts
    • Nakamura T., et al. Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts. Cell 2007, 130:811-823.
    • (2007) Cell , vol.130 , pp. 811-823
    • Nakamura, T.1
  • 25
    • 33748906063 scopus 로고    scopus 로고
    • High-sensitivity C-reactive protein and fracture risk in elderly women
    • Pasco J.A., et al. High-sensitivity C-reactive protein and fracture risk in elderly women. JAMA 2006, 296:1353-1355.
    • (2006) JAMA , vol.296 , pp. 1353-1355
    • Pasco, J.A.1
  • 26
    • 43249118596 scopus 로고    scopus 로고
    • Circulating levels of inflammatory markers predict change in bone mineral density and resorption in older adults: a longitudinal study
    • Ding C., et al. Circulating levels of inflammatory markers predict change in bone mineral density and resorption in older adults: a longitudinal study. J. Clin. Endocrinol. Metab. 2008, 93:1952-1958.
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , pp. 1952-1958
    • Ding, C.1
  • 27
    • 33845474273 scopus 로고    scopus 로고
    • High-sensitivity C-reactive protein and risk of nontraumatic fractures in the Bruneck study
    • Schett G., et al. High-sensitivity C-reactive protein and risk of nontraumatic fractures in the Bruneck study. Arch. Intern. Med. 2006, 166:2495-2501.
    • (2006) Arch. Intern. Med. , vol.166 , pp. 2495-2501
    • Schett, G.1
  • 28
    • 84892756562 scopus 로고    scopus 로고
    • High-sensitivity CRP is an independent risk factor for all fractures and vertebral fractures in elderly men: the MrOS Sweden study
    • Eriksson A.L., et al. High-sensitivity CRP is an independent risk factor for all fractures and vertebral fractures in elderly men: the MrOS Sweden study. J. Bone Miner. Res. 2014, 29:418-423.
    • (2014) J. Bone Miner. Res. , vol.29 , pp. 418-423
    • Eriksson, A.L.1
  • 29
    • 34447303828 scopus 로고    scopus 로고
    • Effect of blockade of TNF-alpha and interleukin-1 action on bone resorption in early postmenopausal women
    • Charatcharoenwitthaya N., et al. Effect of blockade of TNF-alpha and interleukin-1 action on bone resorption in early postmenopausal women. J. Bone Miner. Res. 2007, 22:724-729.
    • (2007) J. Bone Miner. Res. , vol.22 , pp. 724-729
    • Charatcharoenwitthaya, N.1
  • 30
    • 79551676415 scopus 로고    scopus 로고
    • Ovariectomy disregulates osteoblast and osteoclast formation through the T-cell receptor CD40 ligand
    • Li J.Y., et al. Ovariectomy disregulates osteoblast and osteoclast formation through the T-cell receptor CD40 ligand. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:768-773.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 768-773
    • Li, J.Y.1
  • 31
    • 0035923727 scopus 로고    scopus 로고
    • Up-regulation of TNF-producing T cells in the bone marrow: a key mechanism by which estrogen deficiency induces bone loss in vivo
    • Roggia C., et al. Up-regulation of TNF-producing T cells in the bone marrow: a key mechanism by which estrogen deficiency induces bone loss in vivo. Proc. Natl. Acad. Sci. U.S.A. 2001, 98:13960-13965.
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 13960-13965
    • Roggia, C.1
  • 32
    • 79952763661 scopus 로고    scopus 로고
    • Succession of microbial consortia in the developing infant gut microbiome
    • Koenig J.E., et al. Succession of microbial consortia in the developing infant gut microbiome. Proc. Natl. Acad. Sci. U.S.A. 2011, 108(Suppl. 1):4578-4585.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 4578-4585
    • Koenig, J.E.1
  • 33
    • 84862141704 scopus 로고    scopus 로고
    • Human gut microbiome viewed across age and geography
    • Yatsunenko T., et al. Human gut microbiome viewed across age and geography. Nature 2012, 486:222-227.
    • (2012) Nature , vol.486 , pp. 222-227
    • Yatsunenko, T.1
  • 34
    • 84904014790 scopus 로고    scopus 로고
    • Tipping elements in the human intestinal ecosystem
    • Published online July 8, 2014
    • Lahti L., et al. Tipping elements in the human intestinal ecosystem. Nat. Commun. 2014, 5. Published online July 8, 2014. 10.1038/ncomms5344.
    • (2014) Nat. Commun. , vol.5
    • Lahti, L.1
  • 35
    • 77955602581 scopus 로고    scopus 로고
    • Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians
    • Published online May 17, 2010
    • Biagi E., et al. Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians. PLoS ONE 2010, Published online May 17, 2010. 10.1371/journal.pone.0010667.
    • (2010) PLoS ONE
    • Biagi, E.1
  • 36
    • 79952757721 scopus 로고    scopus 로고
    • Composition, variability, and temporal stability of the intestinal microbiota of the elderly
    • Claesson M.J., et al. Composition, variability, and temporal stability of the intestinal microbiota of the elderly. Proc. Natl. Acad. Sci. U.S.A. 2011, 108(Suppl. 1):4586-4591.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 4586-4591
    • Claesson, M.J.1
  • 37
    • 84865477413 scopus 로고    scopus 로고
    • Antibiotics in early life alter the murine colonic microbiome and adiposity
    • Cho I., et al. Antibiotics in early life alter the murine colonic microbiome and adiposity. Nature 2012, 488:621-626.
    • (2012) Nature , vol.488 , pp. 621-626
    • Cho, I.1
  • 38
    • 84907563983 scopus 로고    scopus 로고
    • Altering the intestinal microbiota during a critical developmental window has lasting metabolic consequences
    • Cox L.M., et al. Altering the intestinal microbiota during a critical developmental window has lasting metabolic consequences. Cell 2014, 158:705-721.
    • (2014) Cell , vol.158 , pp. 705-721
    • Cox, L.M.1
  • 39
    • 2942625911 scopus 로고    scopus 로고
    • Interactions between commensal intestinal bacteria and the immune system
    • Macpherson A.J., Harris N.L. Interactions between commensal intestinal bacteria and the immune system. Nat. Rev. Immunol. 2004, 4:478-485.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 478-485
    • Macpherson, A.J.1    Harris, N.L.2
  • 40
    • 84861316694 scopus 로고    scopus 로고
    • The gut microbiota regulates bone mass in mice
    • Sjogren K., et al. The gut microbiota regulates bone mass in mice. J. Bone Miner. Res. 2012, 27:1357-1367.
    • (2012) J. Bone Miner. Res. , vol.27 , pp. 1357-1367
    • Sjogren, K.1
  • 41
    • 84923093026 scopus 로고    scopus 로고
    • Gut microbiota plays a pivotal role in the bone loss induced by sex steroid deficiency
    • Li J-Y., et al. Gut microbiota plays a pivotal role in the bone loss induced by sex steroid deficiency. J. Bone Miner. Res. 2014, 29(Suppl. 1):1029.
    • (2014) J. Bone Miner. Res. , vol.29 , pp. 1029
    • Li, J.-Y.1
  • 42
    • 56349162283 scopus 로고    scopus 로고
    • Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum
    • Yadav V.K., et al. Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum. Cell 2008, 135:825-837.
    • (2008) Cell , vol.135 , pp. 825-837
    • Yadav, V.K.1
  • 43
    • 0030446143 scopus 로고    scopus 로고
    • Minocycline prevents the decrease in bone mineral density and trabecular bone in ovariectomized aged rats
    • Williams S., et al. Minocycline prevents the decrease in bone mineral density and trabecular bone in ovariectomized aged rats. Bone 1996, 19:637-644.
    • (1996) Bone , vol.19 , pp. 637-644
    • Williams, S.1
  • 44
    • 4944229454 scopus 로고    scopus 로고
    • Effects of doxycycline on mechanical properties of bones in rats with ovariectomy-induced osteopenia
    • Pytlik M., et al. Effects of doxycycline on mechanical properties of bones in rats with ovariectomy-induced osteopenia. Calcif. Tissue Int. 2004, 75:225-230.
    • (2004) Calcif. Tissue Int. , vol.75 , pp. 225-230
    • Pytlik, M.1
  • 45
    • 0036557819 scopus 로고    scopus 로고
    • Why and how antibiotics are used in swine production
    • Cromwell G.L. Why and how antibiotics are used in swine production. Anim. Biotechnol. 2002, 13:7-27.
    • (2002) Anim. Biotechnol. , vol.13 , pp. 7-27
    • Cromwell, G.L.1
  • 46
    • 84875863443 scopus 로고    scopus 로고
    • An update on the use and investigation of probiotics in health and disease
    • Sanders M.E., et al. An update on the use and investigation of probiotics in health and disease. Gut 2013, 62:787-796.
    • (2013) Gut , vol.62 , pp. 787-796
    • Sanders, M.E.1
  • 47
    • 0029013322 scopus 로고
    • Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics
    • Gibson G.R., Roberfroid M.B. Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J. Nutr. 1995, 125:1401-1412.
    • (1995) J. Nutr. , vol.125 , pp. 1401-1412
    • Gibson, G.R.1    Roberfroid, M.B.2
  • 48
    • 83855165652 scopus 로고    scopus 로고
    • Emerging molecular insights into the interaction between probiotics and the host intestinal mucosa
    • Bron P.A., et al. Emerging molecular insights into the interaction between probiotics and the host intestinal mucosa. Nat. Rev. Microbiol. 2012, 10:66-78.
    • (2012) Nat. Rev. Microbiol. , vol.10 , pp. 66-78
    • Bron, P.A.1
  • 49
    • 33748591579 scopus 로고    scopus 로고
    • The effect of dietary probiotic supplementation on tibial bone characteristics and strength in broilers
    • Mutus R., et al. The effect of dietary probiotic supplementation on tibial bone characteristics and strength in broilers. Poult. Sci. 2006, 85:1621-1625.
    • (2006) Poult. Sci. , vol.85 , pp. 1621-1625
    • Mutus, R.1
  • 50
    • 77749322389 scopus 로고    scopus 로고
    • A novel probiotic mixture exerts a therapeutic effect on experimental autoimmune encephalomyelitis mediated by IL-10 producing regulatory T cells
    • Published online February 2, 2010
    • Lavasani S., et al. A novel probiotic mixture exerts a therapeutic effect on experimental autoimmune encephalomyelitis mediated by IL-10 producing regulatory T cells. PLoS ONE 2010, Published online February 2, 2010. 10.1371/journal.pone.0009009.
    • (2010) PLoS ONE
    • Lavasani, S.1
  • 51
    • 84898612135 scopus 로고    scopus 로고
    • Probiotics protect mice from ovariectomy-induced cortical bone loss
    • Published online March 17, 2014
    • Ohlsson C., et al. Probiotics protect mice from ovariectomy-induced cortical bone loss. PLoS ONE 2014, Published online March 17, 2014. 10.1371/journal.pone.0092368.
    • (2014) PLoS ONE
    • Ohlsson, C.1
  • 52
    • 84904893893 scopus 로고    scopus 로고
    • Probiotic L. reuteri treatment prevents bone loss in a menopausal ovariectomized mouse model
    • Britton R.A., et al. Probiotic L. reuteri treatment prevents bone loss in a menopausal ovariectomized mouse model. J. Cell. Physiol. 2014, 229:1822-1830.
    • (2014) J. Cell. Physiol. , vol.229 , pp. 1822-1830
    • Britton, R.A.1
  • 53
    • 84876717358 scopus 로고    scopus 로고
    • Probiotic use decreases intestinal inflammation and increases bone density in healthy male but not female mice
    • McCabe L.R., et al. Probiotic use decreases intestinal inflammation and increases bone density in healthy male but not female mice. J. Cell. Physiol. 2013, 228:1793-1798.
    • (2013) J. Cell. Physiol. , vol.228 , pp. 1793-1798
    • McCabe, L.R.1
  • 54
    • 79959256073 scopus 로고    scopus 로고
    • Galactooligosaccharides improve mineral absorption and bone properties in growing rats through gut fermentation
    • Weaver C.M., et al. Galactooligosaccharides improve mineral absorption and bone properties in growing rats through gut fermentation. J. Agric. Food Chem. 2011, 59:6501-6510.
    • (2011) J. Agric. Food Chem. , vol.59 , pp. 6501-6510
    • Weaver, C.M.1
  • 55
    • 84884675439 scopus 로고    scopus 로고
    • Galacto-oligosaccharides increase calcium absorption and gut bifidobacteria in young girls: a double-blind cross-over trial
    • Whisner C.M., et al. Galacto-oligosaccharides increase calcium absorption and gut bifidobacteria in young girls: a double-blind cross-over trial. Br. J. Nutr. 2013, 110:1292-1303.
    • (2013) Br. J. Nutr. , vol.110 , pp. 1292-1303
    • Whisner, C.M.1
  • 56
    • 24044541066 scopus 로고    scopus 로고
    • A combination of prebiotic short- and long-chain inulin-type fructans enhances calcium absorption and bone mineralization in young adolescents
    • Abrams S.A., et al. A combination of prebiotic short- and long-chain inulin-type fructans enhances calcium absorption and bone mineralization in young adolescents. Am. J. Clin. Nutr. 2005, 82:471-476.
    • (2005) Am. J. Clin. Nutr. , vol.82 , pp. 471-476
    • Abrams, S.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.