Insulin receptor substrate-2 is expressed in kidney epithelium and up-regulated in diabetic nephropathy

FEBS Journal

Volumn 280, Issue 14, 2013, Pages 3232-3243

  Hookham, Michelle B ^a   O'Donovan, Helen C ^b   Church, Rachel H ^a   Mercier Zuber, Annie ^c   Luzi, Lucilla ^d   Curran, Simon P ^b   Carew, Rosemarie M ^b   Droguett, Alejandra ^e   Mezzano, Sergio ^e   Schubert, Markus ^f   White, Morris F ^g   Crean, John K ^b   Brazil, Derek P ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^e UNIVERSIDAD AUSTRAL DE CHILE   (Chile)

^f UNIVERSITY OF COLOGNE   (Germany)

^g BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

bone morphogenetic protein; diabetes; insulin receptor substrate; kidney; nephropathy

Indexed keywords

INSULIN RECEPTOR SUBSTRATE 2; MESSENGER RNA; OSTEOGENIC PROTEIN 1; PHOSPHATIDYLINOSITOL 3 KINASE; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; AGED; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DISEASE COURSE; DISEASE MARKER; DISEASE SEVERITY; ELECTROPHORETIC MOBILITY; ENZYME PHOSPHORYLATION; FEMALE; HELA CELL; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN SITU HYBRIDIZATION; INTRACELLULAR SIGNALING; KIDNEY TUBULE EPITHELIUM; MALE; MOUSE; NEPHRON; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEINURIA; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

BONE MORPHOGENETIC PROTEIN; DIABETES; INSULIN RECEPTOR SUBSTRATE; KIDNEY; NEPHROPATHY;

ADOLESCENT; ADULT; ANIMALS; BASE SEQUENCE; BINDING SITES; BONE MORPHOGENETIC PROTEIN 7; CASE-CONTROL STUDIES; CELL LINE; CHILD; DIABETIC NEPHROPATHIES; EPITHELIUM; FEMALE; GENE EXPRESSION; HUMANS; INSULIN RECEPTOR SUBSTRATE PROTEINS; KIDNEY TUBULES; MALE; MICE; MIDDLE AGED; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; SIGNAL TRANSDUCTION; SMAD4 PROTEIN; TRANSCRIPTIONAL ACTIVATION; YOUNG ADULT;

EID: 84879981170     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12305     Document Type: Article

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