Fibroblast growth factor 2-induced cytoplasmic asparaginyl-tRNA synthetase promotes survival of osteoblasts by regulating anti-apoptotic PI3K/Akt signaling

Bone

Volumn 45, Issue 5, 2009, Pages 994-1003

  Park, Su Jin ^a   Kim, Seong Hwan ^c   Choi, Han Seok ^b   Rhee, Yumie ^b   Lim, Sung Kil ^a,b  

^a Yonsei University College of Medicine   (South Korea)

^b AdipoGen Inc   (South Korea)

^c Korea Research Institute of Chemical Technology   (South Korea)

Author keywords

FGF2; NARS; Osteoblasts; PI3K Akt pathway; Survival

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ALPHA GLUCOSIDASE; ALPHA GLUCOSIDASE 2ALPHA; ASPARAGINYL TRANSFER RIBONUCLEIC ACID SYNTHETASE; BETA TROPOMYOSIN; BIOLOGICAL FACTOR; CASPASE 3; EUKARYOTIC TRANSLATION TERMINATION FACTOR 2; FIBROBLAST GROWTH FACTOR 2; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 84; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; SMALL INTERFERING RNA; SORTING NEXIN 9; SUCCINYL COENZYME A SYNTHETASE; SYNTHETASE; TROPOMYOSIN; TROPOMYOSIN 2; UNCLASSIFIED DRUG; WORTMANNIN;

ANIMAL CELL; ANIMAL CELL CULTURE; APOPTOSIS; ARTICLE; CALVARIA; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; GENE OVEREXPRESSION; GENETIC TRANSFECTION; MOUSE; NONHUMAN; OSTEOBLAST; PROTEOMICS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TWO DIMENSIONAL GEL ELECTROPHORESIS; UPREGULATION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; ASPARTATE-TRNA LIGASE; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CYTOPLASM; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENZYME INDUCTION; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MICE; OSTEOBLASTS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; RNA, MESSENGER; RNA, SMALL INTERFERING; RNA, TRANSFER, AMINO ACYL; SIGNAL TRANSDUCTION; SKULL; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 70349414307     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2009.07.018     Document Type: Article

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