Making sense of amino acid sensing

Science

Volumn 347, Issue 6218, 2015, Pages 128-129

  Abraham, Robert T ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; AMINO ACID; AMINO ACID MIXTURE; AMINO ACID TRANSPORTER; ARGININE; BREFELDIN A; GLUTAMINE; GROWTH FACTOR; GUANOSINE TRIPHOSPHATASE; HETERODIMER; LEUCINE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RAPAMYCIN; XENOBIOTIC AGENT; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MONOMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; MULTIPROTEIN COMPLEX; RAGA PROTEIN, MOUSE; RAGB PROTEIN, MOUSE; SLC38A9 PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

AMINO ACID; GROWTH RATE; MAMMAL; METABOLISM; NUTRIENT AVAILABILITY; SIGNALING;

AMINO ACID METABOLISM; AMINO ACID TRANSPORT; CELL CULTURE; CELL GROWTH; CELL MEMBRANE; CELL ORGANELLE; COLORECTAL CANCER; CYTOPLASM; ENDOPLASMIC RETICULUM; GOLGI COMPLEX; HUMAN; LYSOSOME; LYSOSOME MEMBRANE; MAMMAL CELL; MEMBRANE STRUCTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE; SHORT SURVEY; ANIMAL; ENZYMOLOGY; METABOLISM;

AMINO ACID TRANSPORT SYSTEMS; ANIMALS; ARGININE; GLUTAMINE; HUMANS; LEUCINE; LYSOSOMES; MONOMERIC GTP-BINDING PROTEINS; MULTIPROTEIN COMPLEXES; TOR SERINE-THREONINE KINASES;

EID: 84923277043     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aaa4570     Document Type: Short Survey

References (13)

1. R. Zoncu, A. Efeyan, D. M. Sabatini, Nat. Rev. Mol. Cell Biol. 12, 21 (2011).
2. J. L. Jewell, R. C. Russell, K. L. Guan, Nat. Rev. Mol. Cell Biol. 14, 133 (2013).
3. Y. Sancak et al., Science 320, 1496 (2008).
4. E. Kim, P. Goraksha-Hicks, L. Li, T. P. Neufeld, K. L. Guan, Nat. Cell Biol. 10, 935 (2008).
5. R. Zoncu et al., Science 334, 678 (2011).
6. S. Wang et al., Science 347, 188 (2015).
7. M. Rebsamen et al., Nature 10.1038/nature14107 (2015).
8. J. D. Thomas et al., Cancer Cell 26, 754 (2014).
9. J. L. Jewell, Science 347, 194 (2015).
10. C. C. Dibble, B. D. Manning, Nat. Cell Biol. 15, 555 (2013).
11. P. J. Höglund, K. J. Nordström, H. B. Schiöth, R. Fredriksson, Mol. Biol. Evol. 28, 1531 (2011).
12. Y. Sancak et al., Cell 141, 290 (2010).
13. J. Sanchez-Gurmaches, D. A. Guertin, Cancer Cell 26, 601 (2014).