Targeting type 2 diabetes: lessons from a knockout model of insulin receptor substrate 2

Canadian Journal of Physiology and Pharmacology

Volumn 92, Issue 8, 2014, Pages 613-620

  Oliveira, Joana Moitinho ^a,b,d   Rebuffat, Sandra A ^a,b   Gasa, Rosa ^a,b   Gomis, Ramon ^a,b,c  

^a INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c HOSPITAL CLÍNIC   (Spain)

^d UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

Apoptosis; Beta cell; Insulin receptor substrate 2; Survival; Type 2 diabetes

Indexed keywords

INSULIN RECEPTOR SUBSTRATE; IRS1 PROTEIN, MOUSE; IRS2 PROTEIN, HUMAN; IRS2 PROTEIN, MOUSE;

ANIMAL; ANTIBODY SPECIFICITY; DIABETES MELLITUS, TYPE 2; DISEASE MODEL; GENETICS; HUMAN; INSULIN RESISTANCE; KNOCKOUT MOUSE; METABOLISM; MOUSE; PANCREAS; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; HUMANS; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; MICE; MICE, KNOCKOUT; ORGAN SPECIFICITY; PANCREAS; SIGNAL TRANSDUCTION;

EID: 84904984457     PISSN: 00084212     EISSN: 12057541     Source Type: Journal    
DOI: 10.1139/cjpp-2014-0114     Document Type: Review

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